Recent Advances in the Discovery of Nicotinic Acetylcholine Receptor Allosteric Modulators
Manetti, Dina, Dei, Silvia, Arias, Hugo R, Braconi, Laura, Gabellini, Alessio, Teodori, Elisabetta, Romanelli, Maria Novella
Published in Molecules (Basel, Switzerland) (28.01.2023)
Published in Molecules (Basel, Switzerland) (28.01.2023)
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Journal Article
The role of inflammation in Alzheimer's disease
Tuppo, Ehab E., Arias, Hugo R.
Published in The international journal of biochemistry & cell biology (01.02.2005)
Published in The international journal of biochemistry & cell biology (01.02.2005)
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Journal Article
Role of Nicotinic and Muscarinic Receptors on Synaptic Plasticity and Neurological Diseases
Fuenzalida, Marco, Pérez, Miguel Ángel, Arias, Hugo R
Published in Current pharmaceutical design (01.04.2016)
Published in Current pharmaceutical design (01.04.2016)
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Journal Article
Exploring the positive allosteric modulation of human α7 nicotinic receptors from a single-channel perspective
Andersen, Natalia D., Nielsen, Beatriz E., Corradi, Jeremías, Tolosa, María F., Feuerbach, Dominik, Arias, Hugo R., Bouzat, Cecilia
Published in Neuropharmacology (01.08.2016)
Published in Neuropharmacology (01.08.2016)
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Journal Article
Modulation of the mammalian GABAA receptor by type I and type II positive allosteric modulators of the α7 nicotinic acetylcholine receptor
Arias, Hugo R., Germann, Allison L., Pierce, Spencer R., Sakamoto, Seiji, Ortells, Marcelo O., Hamachi, Itaru, Akk, Gustav
Published in British journal of pharmacology (01.12.2022)
Published in British journal of pharmacology (01.12.2022)
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Journal Article
3-Furan-2-yl-N-p-tolyl-acrylamide, a positive allosteric modulator of the α7 nicotinic receptor, reverses schizophrenia-like cognitive and social deficits in rats
Potasiewicz, Agnieszka, Hołuj, Małgorzata, Kos, Tomasz, Popik, Piotr, Arias, Hugo R., Nikiforuk, Agnieszka
Published in Neuropharmacology (01.02.2017)
Published in Neuropharmacology (01.02.2017)
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Journal Article
Non-hallucinogenic compounds derived from iboga alkaloids alleviate neuropathic and visceral pain in mice through a mechanism involving 5-HT2A receptor activation
Arias, Hugo R., Micheli, Laura, Rudin, Deborah, Bento, Ophelie, Borsdorf, Saskia, Ciampi, Clara, Marin, Philippe, Ponimaskin, Evgeni, Manetti, Dina, Romanelli, Maria Novella, Ghelardini, Carla, Liechti, Matthias E., Di Cesare Mannelli, Lorenzo
Published in Biomedicine & pharmacotherapy (01.08.2024)
Published in Biomedicine & pharmacotherapy (01.08.2024)
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Journal Article
(E)‑3-Furan-2-yl‑N‑p‑tolyl-acrylamide and its Derivative DM489 Decrease Neuropathic Pain in Mice Predominantly by α7 Nicotinic Acetylcholine Receptor Potentiation
Arias, Hugo R, Ghelardini, Carla, Lucarini, Elena, Tae, Han-Shen, Yousuf, Arsalan, Marcovich, Irina, Manetti, Dina, Romanelli, Maria Novella, Elgoyhen, Ana Belén, Adams, David J, Di Cesare Mannelli, Lorenzo
Published in ACS chemical neuroscience (04.11.2020)
Published in ACS chemical neuroscience (04.11.2020)
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Journal Article
Mutational Analysis of Anesthetic Binding Sites and Their Effects on GABAA Receptor Activation and Modulation by Positive Allosteric Modulators of the α7 Nicotinic Receptor
Pierce, Spencer R., Germann, Allison L., Xu, Sophia Q., Menon, Saumith L., Ortells, Marcelo O., Arias, Hugo R., Akk, Gustav
Published in Biomolecules (Basel, Switzerland) (20.04.2023)
Published in Biomolecules (Basel, Switzerland) (20.04.2023)
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Journal Article
3-Furan-2-yl-N-p-tolyl-acrylamide, a highly selective positive allosteric modulator of α7 nicotinic receptors, produces anxiolytic-like activity in mice
Targowska-Duda, Katarzyna M, Budzynska, Barbara, Michalak, Agnieszka, Jozwiak, Krzysztof, Biala, Grazyna, Arias, Hugo R
Published in Journal of psychopharmacology (Oxford) (01.05.2019)
Published in Journal of psychopharmacology (Oxford) (01.05.2019)
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Journal Article
Similarities between the Binding Sites of SB-206553 at Serotonin Type 2 and Alpha7 Acetylcholine Nicotinic Receptors: Rationale for Its Polypharmacological Profile
Möller-Acuña, Patricia, Contreras-Riquelme, J Sebastián, Rojas-Fuentes, Cecilia, Nuñez-Vivanco, Gabriel, Alzate-Morales, Jans, Iturriaga-Vásquez, Patricio, Arias, Hugo R, Reyes-Parada, Miguel
Published in PloS one (05.08.2015)
Published in PloS one (05.08.2015)
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Journal Article
Novel Positive Allosteric Modulators of the Human α7 Nicotinic Acetylcholine Receptor
Arias, Hugo R, Gu, Ruo-Xu, Feuerbach, Dominik, Guo, Bao-Bao, Ye, Yong, Wei, Dong-Qing
Published in Biochemistry (Easton) (14.06.2011)
Published in Biochemistry (Easton) (14.06.2011)
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Journal Article
Inhibitory mechanisms and binding site location for serotonin selective reuptake inhibitors on nicotinic acetylcholine receptors
Arias, Hugo R., Feuerbach, Dominik, Bhumireddy, Pankaj, Ortells, Marcelo O.
Published in The international journal of biochemistry & cell biology (01.05.2010)
Published in The international journal of biochemistry & cell biology (01.05.2010)
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Journal Article
To what extent may aminochrome increase the vulnerability of dopaminergic neurons in the context of Parkinson's disease
Chagraoui, Abdeslam, Anouar, Youssef, De Deurwaerdere, Philippe, Arias, Hugo R.
Published in The international journal of biochemistry & cell biology (01.03.2024)
Published in The international journal of biochemistry & cell biology (01.03.2024)
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Journal Article
Theoretical studies of Alzheimer’s disease drug candidate 3-[(2,4-dimethoxy)benzylidene]-anabaseine (GTS-21) and its derivatives
Wei, Dong-Qing, Sirois, Suzane, Du, Qi-Shi, Arias, Hugo R., Chou, Kuo-Chen
Published in Biochemical and biophysical research communications (16.12.2005)
Published in Biochemical and biophysical research communications (16.12.2005)
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Journal Article