Genome-wide chromatin contacts of super-enhancer-associated lncRNA identify LINC01013 as a regulator of fibrosis in the aortic valve
Chignon, Arnaud, Argaud, Déborah, Boulanger, Marie-Chloé, Mkannez, Ghada, Bon-Baret, Valentin, Li, Zhonglin, Thériault, Sébastien, Bossé, Yohan, Mathieu, Patrick
Published in PLoS genetics (18.01.2022)
Published in PLoS genetics (18.01.2022)
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Enhancer promoter interactome and Mendelian randomization identify network of druggable vascular genes in coronary artery disease
Chignon, Arnaud, Mathieu, Samuel, Rufiange, Anne, Argaud, Déborah, Voisine, Pierre, Bossé, Yohan, Arsenault, Benoit J, Thériault, Sébastien, Mathieu, Patrick
Published in Human genomics (04.03.2022)
Published in Human genomics (04.03.2022)
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Enhancer-associated aortic valve stenosis risk locus 1p21.2 alters NFATC2 binding site and promotes fibrogenesis
Chignon, Arnaud, Rosa, Mickael, Boulanger, Marie-Chloé, Argaud, Déborah, Devillers, Romain, Bon-Baret, Valentin, Mkannez, Ghada, Li, Zhonglin, Rufiange, Anne, Gaudreault, Nathalie, Gosselin, David, Thériault, Sébastien, Bossé, Yohan, Mathieu, Patrick
Published in iScience (19.03.2021)
Published in iScience (19.03.2021)
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Integrative genomic analyses identify candidate causal genes for calcific aortic valve stenosis involving tissue-specific regulation
Thériault, Sébastien, Li, Zhonglin, Abner, Erik, Luan, Jian’an, Manikpurage, Hasanga D., Houessou, Ursula, Zamani, Pardis, Briend, Mewen, Boudreau, Dominique K., Gaudreault, Nathalie, Frenette, Lily, Argaud, Déborah, Dahmene, Manel, Dagenais, François, Clavel, Marie-Annick, Pibarot, Philippe, Arsenault, Benoit J., Boekholdt, S. Matthijs, Wareham, Nicholas J., Esko, Tõnu, Mathieu, Patrick, Bossé, Yohan
Published in Nature communications (18.03.2024)
Published in Nature communications (18.03.2024)
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OxLDL-derived lysophosphatidic acid promotes the progression of aortic valve stenosis through a LPAR1-RhoA-NF-κB pathway
Nsaibia, Mohamed Jalloul, Boulanger, Marie-Chloé, Bouchareb, Rihab, Mkannez, Ghada, Le Quang, Khai, Hadji, Fayez, Argaud, Deborah, Dahou, Abdellaziz, Bossé, Yohan, Koschinsky, Marlys L, Pibarot, Philippe, Arsenault, Benoit J, Marette, André, Mathieu, Patrick
Published in Cardiovascular research (01.09.2017)
Published in Cardiovascular research (01.09.2017)
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DNA methylation of a PLPP3 MIR transposon-based enhancer promotes an osteogenic programme in calcific aortic valve disease
Mkannez, Ghada, Gagné-Ouellet, Valérie, Jalloul Nsaibia, Mohamed, Boulanger, Marie-Chloé, Rosa, Mickael, Argaud, Deborah, Hadji, Fayez, Gaudreault, Nathalie, Rhéaume, Gabrielle, Bouchard, Luigi, Bossé, Yohan, Mathieu, Patrick
Published in Cardiovascular research (01.09.2018)
Published in Cardiovascular research (01.09.2018)
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System Genetics Including Causal Inference Identify Immune Targets for Coronary Artery Disease and the Lifespan
Bon-Baret, Valentin, Chignon, Arnaud, Boulanger, Marie-Chloé, Li, Zhonglin, Argaud, Deborah, Arsenault, Benoit J, Thériault, Sébastien, Bossé, Yohan, Mathieu, Patrick
Published in Circulation. Genomic and precision medicine (01.04.2021)
Published in Circulation. Genomic and precision medicine (01.04.2021)
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Single-cell expression and Mendelian randomization analyses identify blood genes associated with lifespan and chronic diseases
Chignon, Arnaud, Bon-Baret, Valentin, Boulanger, Marie-Chloé, Li, Zhonglin, Argaud, Deborah, Bossé, Yohan, Thériault, Sébastien, Arsenault, Benoit J., Mathieu, Patrick
Published in Communications biology (01.05.2020)
Published in Communications biology (01.05.2020)
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