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Donanemab in Early Alzheimer’s Disease
Mintun, Mark A, Lo, Albert C, Duggan Evans, Cynthia, Wessels, Alette M, Ardayfio, Paul A, Andersen, Scott W, Shcherbinin, Sergey, Sparks, JonDavid, Sims, John R, Brys, Miroslaw, Apostolova, Liana G, Salloway, Stephen P, Skovronsky, Daniel M
Published in The New England journal of medicine (06.05.2021)
Published in The New England journal of medicine (06.05.2021)
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Drug-Induced Steatosis and Steatohepatitis: The Search for Novel Serum Biomarkers Among Potential Biomarkers for Non-Alcoholic Fatty Liver Disease and Non-Alcoholic Steatohepatitis
Pavlik, Lauren, Regev, Arie, Ardayfio, Paul A., Chalasani, Naga P.
Published in Drug safety (01.06.2019)
Published in Drug safety (01.06.2019)
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Donanemab (LY3002813) dose‐escalation study in Alzheimer's disease
Lowe, Stephen Loucian, Willis, Brian A., Hawdon, Anne, Natanegara, Fanni, Chua, Laiyi, Foster, Joanne, Shcherbinin, Sergey, Ardayfio, Paul, Sims, John R.
Published in Alzheimer's & dementia : translational research & clinical interventions (2021)
Published in Alzheimer's & dementia : translational research & clinical interventions (2021)
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TRAILBLAZER‐ALZ 4: A phase 3 trial comparing donanemab with aducanumab on amyloid plaque clearance in early, symptomatic Alzheimer's disease
Salloway, Stephen, Pain, Andrew, Lee, Elly, Papka, Michelle, Ferguson, Margaret B., Wang, Hong, Hu, Haoyan, Lu, Ming, Oru, Ena, Ardayfio, Paul A., Hoban, Deirdre B., Collins, Emily C., Brooks, Dawn A., Sims, John R.
Published in Alzheimer's & dementia (01.05.2025)
Published in Alzheimer's & dementia (01.05.2025)
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Pitx3 deficient mice as a genetic animal model of co-morbid depressive disorder and parkinsonism
Kim, Kyoung-Shim, Kang, Young-Mi, Kang, Young, Park, Tae-Shin, Park, Hye-Yeon, Kim, Yoon-Jung, Han, Baek-Soo, Kim, Chun-Hyung, Lee, Chul-Ho, Ardayfio, Paul A., Han, Pyung-Lim, Jung, Bong-Hyun, Kim, Kwang-Soo
Published in Brain research (13.03.2014)
Published in Brain research (13.03.2014)
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Using Clinical Scales and Digital Measures to Explore Falls in Patients with Lewy Body Dementia
Battioui, Chakib, Man, Albert, Pugh, Melissa, Wang, Jian, Dang, Xiangnan, Zhang, Hui, Ardayfio, Paul, Munsie, Leanne, Hake, Ann Marie, Biglan, Kevin M
Published in Digital biomarkers (21.06.2023)
Published in Digital biomarkers (21.06.2023)
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Consequences of constitutive deletion of melanin-concentrating hormone-1 receptors for feeding and foraging behaviors of mice
Eiler, William J.A., Chen, Yanyun, Slieker, Lawrence J., Ardayfio, Paul A., Statnick, Michael A., Witkin, Jeffrey M.
Published in Behavioural brain research (01.01.2017)
Published in Behavioural brain research (01.01.2017)
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Preclinical Evaluation of Melanin-Concentrating Hormone Receptor 1 Antagonism for the Treatment of Obesity and Depression
Gehlert, Donald R., Rasmussen, Kurt, Shaw, Janice, Li, Xia, Ardayfio, Paul, Craft, Libbey, Coskun, Tamer, Zhang, Hong Y., Chen, Yanyun, Witkin, Jeffrey M.
Published in The Journal of pharmacology and experimental therapeutics (01.05.2009)
Published in The Journal of pharmacology and experimental therapeutics (01.05.2009)
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Impaired learning and memory in Pitx3 deficient aphakia mice: A genetic model for striatum-dependent cognitive symptoms in Parkinson's disease
Ardayfio, Paul, Moon, JiSook, Leung, Ka Ka Amanda, Youn-Hwang, Dong, Kim, Kwang-Soo
Published in Neurobiology of disease (01.09.2008)
Published in Neurobiology of disease (01.09.2008)
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The 5-Hydroxytryptamine2A Receptor Antagonist R-(+)-α-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl-4-piperidinemethanol (M100907) Attenuates Impulsivity after Both Drug-Induced Disruption (Dizocilpine) and Enhancement (Antidepressant Drugs) of Differential-Reinforcement-of-Low-Rate 72-s Behavior in the Rat
Ardayfio, Paul A., Benvenga, Mark J., Chaney, Stephen F., Love, Patrick L., Catlow, John, Swanson, Steven P., Marek, Gerard J.
Published in The Journal of pharmacology and experimental therapeutics (01.12.2008)
Published in The Journal of pharmacology and experimental therapeutics (01.12.2008)
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Donanemab in Early Symptomatic Alzheimer Disease: The TRAILBLAZER-ALZ 2 Randomized Clinical Trial
Sims, John R, Zimmer, Jennifer A, Evans, Cynthia D, Lu, Ming, Ardayfio, Paul, Sparks, JonDavid, Wessels, Alette M, Shcherbinin, Sergey, Wang, Hong, Monkul Nery, Emel Serap, Collins, Emily C, Solomon, Paul, Salloway, Stephen, Apostolova, Liana G, Hansson, Oskar, Ritchie, Craig, Brooks, Dawn A, Mintun, Mark, Skovronsky, Daniel M
Published in JAMA : the journal of the American Medical Association (08.08.2023)
Published in JAMA : the journal of the American Medical Association (08.08.2023)
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Donanemab Population Pharmacokinetics, Amyloid Plaque Reduction, and Safety in Participants with Alzheimer's Disease
Gueorguieva, Ivelina, Willis, Brian A., Chua, Laiyi, Chow, Kay, Ernest, C. Steven, Shcherbinin, Sergey, Ardayfio, Paul, Mullins, Garrett R., Sims, John R.
Published in Clinical pharmacology and therapeutics (01.06.2023)
Published in Clinical pharmacology and therapeutics (01.06.2023)
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Drug-Induced Steatosis and Steatohepatitis: The Search for Novel Serum Biomarkers Among Potential Biomarkers for Non-Alcoholic Fatty Liver Disease and Non.Alcoholic Steatohepatitis
Pavlik, Lauren, Regev, Arie, Ardayfio, Paul A, Chalasani, Naga P
Published in Drug safety (01.06.2019)
Published in Drug safety (01.06.2019)
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Effects of Lasmiditan on Cardiovascular Parameters and Pharmacokinetics in Healthy Subjects Receiving Oral Doses of Propranolol
Tsai, Max, Case, Michael, Ardayfio, Paul, Hochstetler, Helen, Wilbraham, Darren
Published in Clinical pharmacology in drug development (01.07.2020)
Published in Clinical pharmacology in drug development (01.07.2020)
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Amyloid-Related Imaging Abnormalities With Donanemab in Early Symptomatic Alzheimer Disease: Secondary Analysis of the TRAILBLAZER-ALZ and ALZ 2 Randomized Clinical Trials
Zimmer, Jennifer A, Ardayfio, Paul, Wang, Hong, Khanna, Rashna, Evans, Cynthia D, Lu, Ming, Sparks, JonDavid, Andersen, Scott, Lauzon, Steve, Nery, Emel Serap Monkul, Battioui, Chakib, Engle, Staci E, Biffi, Alessandro, Svaldi, Diana, Salloway, Stephen, Greenberg, Steven M, Sperling, Reisa A, Mintun, Mark, Brooks, Dawn A, Sims, John R
Published in Archives of neurology (Chicago) (01.05.2025)
Published in Archives of neurology (Chicago) (01.05.2025)
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ARIA Insights from the Donanemab Trials (P1-9.001)
Greenberg, Steven, Battioui, Chakib, Lu, Ming, Biffi, Alessandro, Ardayfio, Paul, Zimmer, Jennifer, Evans, Cynthia, Wang, Hong, Nery, Emel Serap Monkul, Sparks, JonDavid, Andersen, Scott, Collins, Emily, Brooks, Dawn, Sims, John
Published in Neurology (09.04.2024)
Published in Neurology (09.04.2024)
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Modified titration of donanemab reduces ARIA risk and maintains amyloid reduction
Wang, Hong, Serap Monkul Nery, Emel, Ardayfio, Paul, Khanna, Rashna, Otero Svaldi, Diana, Gueorguieva, Ivelina, Shcherbinin, Sergey, Andersen, Scott W., Hauck, Paula M., Engle, Staci E., Brooks, Dawn A., Collins, Emily C., Fox, Nick C., Greenberg, Steven M., Salloway, Stephen, Mintun, Mark A., Sims, John R.
Published in Alzheimer's & dementia (01.04.2025)
Published in Alzheimer's & dementia (01.04.2025)
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