Trial in progress: A phase 2 study of sotorasib as first-line treatment in patients with stage IV non–small cell lung cancer (NSCLC) whose tumors harbor a KRAS p.G12C mutation (CodeBreaK 201)
Arbour, Kathryn Cecilia, Khurana, Monica, Dai, Tian, Skoulidis, Ferdinandos
Published in Journal of clinical oncology (01.06.2022)
Published in Journal of clinical oncology (01.06.2022)
Get full text
Journal Article
Validation of broad panel clinical sequencing-based genomic risk stratification in patients with advanced lung adenocarcinomas
Whipple, Sam, Martin, Axel, Martinec, Michael, Arbour, Kathryn Cecilia, Seshan, Venkatraman E., Riely, Gregory J., Crane, Gracy, Shen, Ronglai
Published in Journal of clinical oncology (20.05.2019)
Published in Journal of clinical oncology (20.05.2019)
Get full text
Journal Article
Chemo-immunotherapy outcomes of KRAS-G12C mutant lung cancer compared to other molecular subtypes of KRAS-mutant lung cancer
Arbour, Kathryn Cecilia, Ricciuti, Biagio, Rizvi, Hira, Hellmann, Matthew D., Yu, Helena Alexandra, Ladanyi, Marc, Kris, Mark G., Arcila, Maria E., Rudin, Charles M., Lito, Piro, Awad, Mark M., Riely, Gregory J.
Published in Journal of clinical oncology (20.05.2021)
Published in Journal of clinical oncology (20.05.2021)
Get full text
Journal Article
Clinical characteristics and anti-PD-(L)1 treatment outcomes of KRAS-G12C mutant lung cancer compared to other molecular subtypes of KRAS-mutant lung cancer
Arbour, Kathryn Cecilia, Rizvi, Hira, Plodkowski, Andrew J., Halpenny, Darragh, Hellmann, Matthew David, Heller, Glenn, Knezevic, Andrea, Yu, Helena Alexandra, Ladanyi, Marc, Kris, Mark G., Arcila, Maria E., Rudin, Charles M., Lito, Piro, Riely, Gregory J.
Published in Journal of clinical oncology (20.05.2020)
Published in Journal of clinical oncology (20.05.2020)
Get full text
Journal Article
Association of a very high tumor mutational load with increased CD8+ and PD-1+ T-cell infiltration and improved clinical outcomes to PD-(L)1 blockade across different PD-L1 expression levels in non-small cell lung cancer
Ricciuti, Biagio, Arbour, Kathryn Cecilia, Alessi, Joao Victor Machado, Mahadevan, Navin, Lindsay, James, Sinha, Rileen, Vokes, Natalie I., Recondo, Gonzalo, Lamberti, Giuseppe, Rizvi, Hira, Leonardi, Giulia Costanza, Plodkowski, Andrew J., Felt, Kristen, Tolstorukov, Michael, Janne, Pasi A., Van Allen, Eliezer Mendel, Sholl, Lynette M., Rodig, Scott J., Hellmann, Matthew D., Awad, Mark M.
Published in Journal of clinical oncology (20.05.2021)
Published in Journal of clinical oncology (20.05.2021)
Get full text
Journal Article
Molecular correlates of PD-L1 expression in patients with non-small cell lung cancer
Rizvi, Hira, Bandlamudi, Chaitanya, Schoenfeld, Adam Jacob, Sauter, Jennifer L., Arbour, Kathryn Cecilia, Beras, Amanda, Egger, Jacklynn V., Ladanyi, Marc, Donoghue, Mark, Rudin, Charles M., Taylor, Barry S., Hellmann, Matthew David
Published in Journal of clinical oncology (20.05.2019)
Published in Journal of clinical oncology (20.05.2019)
Get full text
Journal Article
Effect of STK11 mutations on efficacy of PD-1 inhibition in non-small cell lung cancer (NSCLC) and dependence on KRAS mutation status
Ricciuti, Biagio, Arbour, Kathryn Cecilia, Lin, Jessica Jiyeong, Vokes, Natalie, Vajdi Hoojghan, Amir, Li, Yvonne Y., Cherniack, Andrew D., Recondo, Gonzalo, Lamberti, Giuseppe, Venkatraman, Deepti, Rizvi, Hira, Egger, Jacklynn V., Plodkowski, Andrew J., Khosrowjerdi, Sara, Digumarthy, Subba R, Nishino, Mizuki, Sholl, Lynette M., Gainor, Justin F., Hellmann, Matthew David, Awad, Mark M.
Published in Journal of clinical oncology (20.05.2020)
Published in Journal of clinical oncology (20.05.2020)
Get full text
Journal Article
Response to osimertinib following treatment with EGF816 in patients with T790M EGFR mutant NSLCLC
Arbour, Kathryn Cecilia, Sequist, Lecia V., Piotrowska, Zofia, Kris, Mark G., Paik, Paul K., Ni, Ai, Plodkowski, Andrew, Riely, Gregory J., Yu, Helena Alexandra
Published in Journal of clinical oncology (20.05.2017)
Published in Journal of clinical oncology (20.05.2017)
Get full text
Journal Article
Clinical and molecular features predicting long-term response (LTR) to anti-PD-(L)1 based therapy in patients with NSCLC
Rizvi, Hira, Plodkowski, Andrew J., Tenet, Megan, Halpenny, Darragh, Long, Niamh, Sauter, Jennifer L., Sanchez-Vega, Francisco, Chatila, Walid K, Schultz, Nikolaus, Ladanyi, Marc, Arbour, Kathryn Cecilia, Chaft, Jamie E., Hellmann, Matthew David
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
Get full text
Journal Article
Analysis of outcomes in metastatic pancreatic cancer: Real-world experience in academic cancer centers
Popa, Elizabeta C., Rabinovich, Emma, Sohal, Davendra, Arbour, Kathryn Cecilia, Kim, Timothy Suyong, Lu, Yao, Christos, Paul J., Khorana, Alok A., Shah, Manish A.
Published in Journal of clinical oncology (01.02.2017)
Published in Journal of clinical oncology (01.02.2017)
Get full text
Journal Article
Outcomes to first-line pembrolizumab in patients with non-small cell lung cancer and a PD-L1 tumor proportion score ≥90
Jimenez Aguilar, Elizabeth, Ricciuti, Biagio, Gainor, Justin F., Nishino, Mizuki, Adeni, Anika E., Subegdjo, Safiya, Khosrowjerdi, Sara, Peterson, Rachel, Digumarthy, Subba, Liu, Corinne, Sauter, Jennifer L., Rizvi, Hira, Arbour, Kathryn Cecilia, Carter, Brett W., Heymach, John, Altan, Mehmet, Hellmann, Matthew David, Awad, Mark M.
Published in Journal of clinical oncology (20.05.2019)
Published in Journal of clinical oncology (20.05.2019)
Get full text
Journal Article
Association of STK11/LKB1 genomic alterations with lack of benefit from the addition of pembrolizumab to platinum doublet chemotherapy in non-squamous non-small cell lung cancer
Skoulidis, Ferdinandos, Arbour, Kathryn Cecilia, Hellmann, Matthew David, Patil, Pradnya Dinkar, Marmarelis, Melina Elpi, Awad, Mark M., Murray, Joseph Christopher, Hellyer, Jessica, Gainor, Justin F., Dimou, Anastasios, Bestvina, Christine M., Shu, Catherine A., Riess, Jonathan W., Blakely, Collin Michael, Pecot, Chad Victor, Mezquita, Laura, Tabbò, Fabrizio, Scheffler, Matthias, Papadimitrakopoulou, Vassiliki, Heymach, John
Published in Journal of clinical oncology (20.05.2019)
Published in Journal of clinical oncology (20.05.2019)
Get full text
Journal Article
PD-L1 expression and response to immunotherapy in patients with MET exon 14-altered non-small cell lung cancers (NSCLC)
Sabari, Joshua K., Montecalvo, Joseph, Chen, Ruqin, Dienstag, Jordan A., Mrad, Chebli, Bergagnini, Isabella, Lai, Wei-Chu Victoria, Arbour, Kathryn Cecilia, Shu, Catherine A., Hellmann, Matthew David, Riely, Gregory J., Kris, Mark G., Rudin, Charles M., Rekhtman, Natasha, Drilon, Alexander E.
Published in Journal of clinical oncology (20.05.2017)
Published in Journal of clinical oncology (20.05.2017)
Get full text
Journal Article
Pulse-continuous dose erlotinib as initial targeted therapy for patients with EGFR -mutant lung cancers with untreated brain metastases
Kris, Mark G., Arbour, Kathryn Cecilia, Riely, Gregory J., Ni, Ai, Beal, Kathryn, Daras, Mariza, Hayes, Sara A., Young, Robert J., Rodriguez, Christopher R, Pao, William, Yu, Helena Alexandra
Published in Journal of clinical oncology (20.05.2017)
Published in Journal of clinical oncology (20.05.2017)
Get full text
Journal Article
Lung cancers with mutations in EGFR exon 18: Molecular characterization and clinical outcomes in response to tyrosine kinase inhibitors
Lai, Wei-Chu Victoria, Ni, Ai, Arcila, Maria E., Huang, James, Sabari, Joshua K., Arbour, Kathryn Cecilia, Rudin, Charles M., Kris, Mark G., Riely, Gregory J., Yu, Helena Alexandra
Published in Journal of clinical oncology (20.05.2017)
Published in Journal of clinical oncology (20.05.2017)
Get full text
Journal Article
Frequency of brain metastases and outcomes in patients with HER2-, KRAS-, and EGFR -mutant lung cancers
Kris, Mark G., Offin, Michael David, Feldman, Daniel L., Ni, Ai, Lai, Wei-Chu Victoria, Arbour, Kathryn Cecilia, Daras, Mariza, Pentsova, Elena, DeAngelis, Lisa Marie, Beal, Kathryn, Young, Robert J., Jordan, Emmet, Arcila, Maria E., Jones, David Randolph, Isbell, James M., Riely, Gregory J., Drilon, Alexander E., Yu, Helena Alexandra, Li, Bob T.
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
Get full text
Journal Article
Deleterious effect of baseline steroids on efficacy of PD-(L)1 blockade in patients with NSCLC
Arbour, Kathryn Cecilia, Mezquita, Laura, Long, Niamh, Rizvi, Hira, Auclin, Edouard, Ni, Ai, Martinez Bernal, Gala, Chaft, Jamie E., Ferrara, Roberto, Lai, Wei-Chu Victoria, Hendriks, Lizza, Sabari, Joshua K., Caramella, Caroline, Plodkowski, Andrew J., Halpenny, Darragh, Planchard, David, Riely, Gregory J., Besse, Benjamin, Hellmann, Matthew David
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
Get full text
Journal Article
Outcomes of EGFR-mutant lung adenocarcinomas (AC) that transform to small cell lung cancer (SCLC)
Marcoux, Nicolas, Gettinger, Scott N., O'Kane, Grainne M., Arbour, Kathryn Cecilia, Neal, Joel W., Husain, Hatim, Evans, Tracey L., Brahmer, Julie R., Muzikansky, Alona, Bonomi, Philip, Del Prete, Salvatore A., Wurtz, Anna, Farago, Anna F., Dias-Santagata, Dora, Mino-Kenudson, Mari, Yu, Helena Alexandra, Wakelee, Heather A., Shepherd, Frances A., Piotrowska, Zofia, Sequist, Lecia V.
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
Get full text
Journal Article
RET -rearranged lung cancers: Immunophenotype and response to immunotherapy
Sabari, Joshua K., Offin, Michael David, Wu, Stephanie L, Ni, Ai, Halpenny, Darragh, Montecalvo, Joseph, Liu, Dazhi, Pak, Terry K., Arbour, Kathryn Cecilia, Lai, Wei-Chu Victoria, Hellmann, Matthew David, Riely, Gregory J., Kris, Mark G., Rudin, Charles M., Rekhtman, Natasha, Li, Bob T., Land, Josiah David, Drilon, Alexander E.
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
Get full text
Journal Article