Impaired macroglial development and axonal conductivity contributes to the neuropathology of DYRK1A-related intellectual disability syndrome
Pijuan, Isabel, Balducci, Elisa, Soto-Sánchez, Cristina, Fernández, Eduardo, Barallobre, María José, Arbonés, Maria L.
Published in Scientific reports (19.11.2022)
Published in Scientific reports (19.11.2022)
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Journal Article
Impaired development of neocortical circuits contributes to the neurological alterations in DYRK1A haploinsufficiency syndrome
Arranz, Juan, Balducci, Elisa, Arató, Krisztina, Sánchez-Elexpuru, Gentzane, Najas, Sònia, Parras, Alberto, Rebollo, Elena, Pijuan, Isabel, Erb, Ionas, Verde, Gaetano, Sahun, Ignasi, Barallobre, Maria J., Lucas, José J., Sánchez, Marina P., de la Luna, Susana, Arbonés, Maria L.
Published in Neurobiology of disease (01.07.2019)
Published in Neurobiology of disease (01.07.2019)
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Journal Article
Dyrk1a haploinsufficiency induces diabetes in mice through decreased pancreatic beta cell mass
Rachdi, Latif, Kariyawasam, Dulanjalee, Guez, Fanny, Aïello, Virginie, Arbonés, Maria L., Janel, Nathalie, Delabar, Jean-Maurice, Polak, Michel, Scharfmann, Raphaël
Published in Diabetologia (01.05.2014)
Published in Diabetologia (01.05.2014)
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Journal Article
Impaired spatial learning strategies and novel object recognition in mice haploinsufficient for the dual specificity tyrosine-regulated kinase-1A (Dyrk1A)
Arqué, Glòria, Fotaki, Vassiliki, Fernández, David, Martínez de Lagrán, María, Arbonés, Maria L, Dierssen, Mara
Published in PloS one (02.07.2008)
Published in PloS one (02.07.2008)
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Journal Article
Over-expression of RCAN1 causes Down syndrome-like hippocampal deficits that alter learning and memory
MARTIN, Katherine R, CORLETT, Alicia, FINKELSTEIN, David I, PRITCHARD, Melanie A, DUBACH, Daphne, MUSTAFA, Tomris, COLEMAN, Harold A, PARKINGTON, Helena C, MERSON, Tobias D, BOURNE, James A, PORTA, Sílvia, ARBONES, Maria L
Published in Human molecular genetics (01.07.2012)
Published in Human molecular genetics (01.07.2012)
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Journal Article
Triplication of DYRK1A causes retinal structural and functional alterations in Down syndrome
Laguna, Ariadna, Barallobre, María-José, Marchena, Miguel-Ángel, Mateus, Catarina, Ramírez, Erika, Martínez-Cue, Carmen, Delabar, Jean M, Castelo-Branco, Miguel, de la Villa, Pedro, Arbonés, Maria L
Published in Human molecular genetics (15.07.2013)
Published in Human molecular genetics (15.07.2013)
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Journal Article
Gene expression analysis of the embryonic subplate
Oeschger, Franziska M, Wang, Wei-Zhi, Lee, Sheena, García-Moreno, Fernando, Goffinet, André M, Arbonés, Maria L, Rakic, Sonja, Molnár, Zoltán
Published in Cerebral cortex (New York, N.Y. 1991) (01.06.2012)
Published in Cerebral cortex (New York, N.Y. 1991) (01.06.2012)
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Journal Article
DYRK1A Kinase Positively Regulates Angiogenic Responses in Endothelial Cells
Rozen, Esteban J., Roewenstrunk, Julia, Barallobre, María José, Di Vona, Chiara, Jung, Carole, Figueiredo, Ana F., Luna, Jeroni, Fillat, Cristina, Arbonés, Maria L., Graupera, Mariona, Valverde, Miguel A., de la Luna, Susana
Published in Cell reports (Cambridge) (08.05.2018)
Published in Cell reports (Cambridge) (08.05.2018)
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Journal Article
The Protein Kinase DYRK1A Regulates Caspase-9-Mediated Apoptosis during Retina Development
Laguna, Ariadna, Aranda, Sergi, Barallobre, María José, Barhoum, Rima, Fernández, Eduardo, Fotaki, Vassiliki, Delabar, Jean Maurice, de la Luna, Susana, de la Villa, Pedro, Arbonés, Maria L.
Published in Developmental cell (01.12.2008)
Published in Developmental cell (01.12.2008)
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Regulated Segregation of Kinase Dyrk1A during Asymmetric Neural Stem Cell Division Is Critical for EGFR-Mediated Biased Signaling
Ferron, Sacri R., Pozo, Natividad, Laguna, Ariadna, Aranda, Sergi, Porlan, Eva, Moreno, Mireia, Fillat, Cristina, de la Luna, Susana, Sánchez, Pilar, Arbonés, María L., Fariñas, Isabel
Published in Cell stem cell (03.09.2010)
Published in Cell stem cell (03.09.2010)
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Journal Article
RCAN1 (DSCR1) increases neuronal susceptibility to oxidative stress: a potential pathogenic process in neurodegeneration
Porta, Sílvia, Serra, Selma A., Huch, Meritxell, Valverde, Miguel A., Llorens, Franc, Estivill, Xavier, Arbonés, Maria L., Martí, Eulàlia
Published in Human molecular genetics (01.05.2007)
Published in Human molecular genetics (01.05.2007)
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Journal Article
Dyrk1A Haploinsufficiency Affects Viability and Causes Developmental Delay and Abnormal Brain Morphology in Mice
Fotaki, Vassiliki, Dierssen, Mara, Alcántara, Soledad, Martínez, Salvador, Martí, Eulàlia, Casas, Caty, Visa, Joana, Soriano, Eduardo, Estivill, Xavier, Arbonés, Maria L.
Published in Molecular and Cellular Biology (01.09.2002)
Published in Molecular and Cellular Biology (01.09.2002)
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Journal Article
DYRK1A-mediated Cyclin D1 Degradation in Neural Stem Cells Contributes to the Neurogenic Cortical Defects in Down Syndrome
Najas, Sònia, Arranz, Juan, Lochhead, Pamela A., Ashford, Anne L., Oxley, David, Delabar, Jean M., Cook, Simon J., Barallobre, María José, Arbonés, Maria L.
Published in EBioMedicine (01.02.2015)
Published in EBioMedicine (01.02.2015)
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Journal Article
Upregulation of RCAN1 causes Down syndrome-like immune dysfunction
Martin, Katherine R, Layton, Daniel, Seach, Natalie, Corlett, Alicia, Barallobre, Maria Jose, Arbonés, Maria L, Boyd, Richard L, Scott, Bernadette, Pritchard, Melanie A
Published in Journal of medical genetics (01.07.2013)
Published in Journal of medical genetics (01.07.2013)
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Journal Article
DSCR1/RCAN1 regulates vesicle exocytosis and fusion pore kinetics: implications for Down syndrome and Alzheimer's disease
Keating, Damien J., Dubach, Daphne, Zanin, Mark P., Yu, Yong, Martin, Katherine, Zhao, Yu-Feng, Chen, Chen, Porta, Sílvia, Arbonés, Maria L., Mittaz, Laureane, Pritchard, Melanie A.
Published in Human molecular genetics (01.04.2008)
Published in Human molecular genetics (01.04.2008)
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Journal Article
Age-associated motor and visuo-spatial learning phenotype in Dyrk1A heterozygous mutant mice
Arqué, Glòria, de Lagrán, María Martínez, Arbonés, Maria L, Dierssen, Mara
Published in Neurobiology of disease (01.11.2009)
Published in Neurobiology of disease (01.11.2009)
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Journal Article
DYRK1A and cognition: A lifelong relationship
Arbones, Maria L., Thomazeau, Aurore, Nakano-Kobayashi, Akiko, Hagiwara, Masatoshi, Delabar, Jean M.
Published in Pharmacology & therapeutics (Oxford) (01.02.2019)
Published in Pharmacology & therapeutics (Oxford) (01.02.2019)
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Journal Article
Differential expression of members of the RCAN family of calcineurin regulators suggests selective functions for these proteins in the brain
Porta, Sílvia, Martí, Eulàlia, De La Luna, Susana, Arbonés, Maria L.
Published in The European journal of neuroscience (01.09.2007)
Published in The European journal of neuroscience (01.09.2007)
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Journal Article
DYRK1A modulates c-MET in pancreatic ductal adenocarcinoma to drive tumour growth
Luna, Jeroni, Boni, Jacopo, Cuatrecasas, Miriam, Bofill-De Ros, Xavier, Núñez-Manchón, Estela, Gironella, Meritxell, Vaquero, Eva C, Arbones, Maria L, de la Luna, Susana, Fillat, Cristina
Published in Gut (01.08.2019)
Published in Gut (01.08.2019)
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