Unified classification and risk-stratification in Acute Myeloid Leukemia
Tazi, Yanis, Arango-Ossa, Juan E., Zhou, Yangyu, Bernard, Elsa, Thomas, Ian, Gilkes, Amanda, Freeman, Sylvie, Pradat, Yoann, Johnson, Sean J., Hills, Robert, Dillon, Richard, Levine, Max F., Leongamornlert, Daniel, Butler, Adam, Ganser, Arnold, Bullinger, Lars, Döhner, Konstanze, Ottmann, Oliver, Adams, Richard, Döhner, Hartmut, Campbell, Peter J., Burnett, Alan K., Dennis, Michael, Russell, Nigel H., Devlin, Sean M., Huntly, Brian J. P., Papaemmanuil, Elli
Published in Nature communications (08.08.2022)
Published in Nature communications (08.08.2022)
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A randomized phase 3 trial of interferon-α vs hydroxyurea in polycythemia vera and essential thrombocythemia
Mascarenhas, John, Kosiorek, Heidi E., Prchal, Josef T., Rambaldi, Alessandro, Berenzon, Dmitriy, Yacoub, Abdulraheem, Harrison, Claire N., McMullin, Mary Frances, Vannucchi, Alessandro M., Ewing, Joanne, O'Connell, Casey L., Kiladjian, Jean-Jacques, Mead, Adam J., Winton, Elliott F., Leibowitz, David S., De Stefano, Valerio, Arcasoy, Murat O., Kessler, Craig M., Catchatourian, Rosalind, Rondelli, Damiano, Silver, Richard T., Bacigalupo, Andrea, Nagler, Arnon, Kremyanskaya, Marina, Levine, Max F., Arango Ossa, Juan E., McGovern, Erin, Sandy, Lonette, Salama, Mohamad E., Najfeld, Vesna, Tripodi, Joseph, Farnoud, Noushin, Penson, Alexander V., Weinberg, Rona Singer, Price, Leah, Goldberg, Judith D., Barbui, Tiziano, Marchioli, Roberto, Tognoni, Gianni, Rampal, Raajit K., Mesa, Ruben A., Dueck, Amylou C., Hoffman, Ronald
Published in Blood (12.05.2022)
Published in Blood (12.05.2022)
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Journal Article
Isabl Platform, a digital biobank for processing multimodal patient data
Medina-Martínez, Juan S, Arango-Ossa, Juan E, Levine, Max F, Zhou, Yangyu, Gundem, Gunes, Kung, Andrew L, Papaemmanuil, Elli
Published in BMC bioinformatics (30.11.2020)
Published in BMC bioinformatics (30.11.2020)
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Journal Article
Clonal evolution during metastatic spread in high-risk neuroblastoma
Gundem, Gunes, Levine, Max F., Roberts, Stephen S., Cheung, Irene Y., Medina-Martínez, Juan S., Feng, Yi, Arango-Ossa, Juan E., Chadoutaud, Loic, Rita, Mathieu, Asimomitis, Georgios, Zhou, Joe, You, Daoqi, Bouvier, Nancy, Spitzer, Barbara, Solit, David B., Dela Cruz, Filemon, LaQuaglia, Michael P., Kushner, Brian H., Modak, Shakeel, Shukla, Neerav, Iacobuzio-Donahue, Christine A., Kung, Andrew L., Cheung, Nai-Kong V., Papaemmanuil, Elli
Published in Nature genetics (01.06.2023)
Published in Nature genetics (01.06.2023)
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Phase 2 study of ruxolitinib and decitabine in patients with myeloproliferative neoplasm in accelerated and blast phase
Mascarenhas, John O., Rampal, Raajit K., Kosiorek, Heidi E., Bhave, Rupali, Hexner, Elizabeth, Wang, Eunice S., Gerds, Aaron, Abboud, Camille N., Kremyanskaya, Marina, Berenzon, Dimitry, Odenike, Olatoyosi, Farnoud, Noushin, Krishnan, Aishwarya, Weinberg, Rona Singer, McGovern, Erin, Salama, Mohamed E., Najfeld, Vesna, Medina-Martinez, Juan S., Arango Ossa, Juan E., Levine, Max F., Zhou, Yangyu, Sandy, Lonette, Heaney, Mark L., Levine, Ross L., Mesa, Ruben A., Dueck, Amylou C., Hoffman, Ronald
Published in Blood advances (27.10.2020)
Published in Blood advances (27.10.2020)
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Interplay between chromosomal alterations and gene mutations shapes the evolutionary trajectory of clonal hematopoiesis
Gao, Teng, Ptashkin, Ryan, Bolton, Kelly L., Sirenko, Maria, Fong, Christopher, Spitzer, Barbara, Menghrajani, Kamal, Ossa, Juan E. Arango, Zhou, Yangyu, Bernard, Elsa, Levine, Max, Martinez, Juan S. Medina, Zhang, Yanming, Franch-Expósito, Sebastià, Patel, Minal, Braunstein, Lior Z., Kelly, Daniel, Yabe, Mariko, Benayed, Ryma, Caltabellotta, Nicole M., Philip, John, Paraiso, Ederlinda, Mantha, Simon, Solit, David B., Diaz, Luis A., Berger, Michael F., Klimek, Virginia, Levine, Ross L., Zehir, Ahmet, Devlin, Sean M., Papaemmanuil, Elli
Published in Nature communications (12.01.2021)
Published in Nature communications (12.01.2021)
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De Novo myelodysplastic syndromes in patients 20–50 years old are enriched for adverse risk features
Epstein-Peterson, Zachary D., Spitzer, Barbara, Derkach, Andriy, Arango, Juan E., McCarter, Joseph G.W., Medina-Martínez, Juan S., McGovern, Erin, Farnoud, Noushin Rahnamay, Levine, Ross L., Tallman, Martin S.
Published in Leukemia research (01.06.2022)
Published in Leukemia research (01.06.2022)
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Journal Article
Molecular taxonomy of myelodysplastic syndromes and its clinical implications
Bernard, Elsa, Hasserjian, Robert P., Greenberg, Peter L., Arango Ossa, Juan E., Creignou, Maria, Tuechler, Heinz, Gutierrez-Abril, Jesus, Domenico, Dylan, Medina-Martinez, Juan S., Levine, Max, Liosis, Konstantinos, Farnoud, Noushin, Sirenko, Maria, Jädersten, Martin, Germing, Ulrich, Sanz, Guillermo, van de Loosdrecht, Arjan A., Nannya, Yasuhito, Kosmider, Olivier, Follo, Matilde Y., Thol, Felicitas, Zamora, Lurdes, Pinheiro, Ronald F., Pellagatti, Andrea, Elias, Harold K., Haase, Detlef, Ganster, Christina, Ades, Lionel, Tobiasson, Magnus, Palomo, Laura, Della Porta, Matteo Giovanni, Fenaux, Pierre, Belickova, Monika, Savona, Michael R., Klimek, Virginia M., Santos, Fabio P. S., Boultwood, Jacqueline, Kotsianidis, Ioannis, Santini, Valeria, Solé, Francesc, Platzbecker, Uwe, Heuser, Michael, Valent, Peter, Finelli, Carlo, Voso, Maria Teresa, Shih, Lee-Yung, Fontenay, Michaela, Jansen, Joop H., Cervera, José, Gattermann, Norbert, Ebert, Benjamin L., Bejar, Rafael, Malcovati, Luca, Ogawa, Seishi, Cazzola, Mario, Hellström-Lindberg, Eva, Papaemmanuil, Elli
Published in Blood (10.10.2024)
Published in Blood (10.10.2024)
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Journal Article
Subclonal Somatic Copy-Number Alterations Emerge and Dominate in Recurrent Osteosarcoma
Kinnaman, Michael D, Zaccaria, Simone, Makohon-Moore, Alvin, Arnold, Brian, Levine, Max F, Gundem, Gunes, Arango Ossa, Juan E, Glodzik, Dominik, Rodríguez-Sánchez, M Irene, Bouvier, Nancy, Li, Shanita, Stockfisch, Emily, Dunigan, Marisa, Cobbs, Cassidy, Bhanot, Umesh K, You, Daoqi, Mullen, Katelyn, Melchor, Jerry P, Ortiz, Michael V, O'Donohue, Tara J, Slotkin, Emily K, Wexler, Leonard H, Dela Cruz, Filemon S, Hameed, Meera R, Glade Bender, Julia L, Tap, William D, Meyers, Paul A, Papaemmanuil, Elli, Kung, Andrew L, Iacobuzio-Donahue, Christine A
Published in Cancer research (Chicago, Ill.) (15.11.2023)
Published in Cancer research (Chicago, Ill.) (15.11.2023)
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Bone Marrow Surveillance of Pediatric Cancer Survivors Identifies Clones that Predict Therapy-Related Leukemia
Spitzer, Barbara, Rutherford, Kayleigh D, Gundem, Gunes, McGovern, Erin M, Millard, Nathan E, Arango Ossa, Juan E, Cheung, Irene Y, Gao, Teng, Levine, Max F, Zhang, Yanming, Medina-Martínez, Juan S, Feng, Yi, Ptashkin, Ryan N, Bolton, Kelly L, Farnoud, Noushin, Zhou, Yangyu, Patel, Minal A, Asimomitis, Georgios, Cobbs, Cassidy C, Mohibullah, Neeman, Huberman, Kety H, Arcilla, Maria E, Kushner, Brian H, Modak, Shakeel, Kung, Andrew L, Zehir, Ahmet, Levine, Ross L, Armstrong, Scott A, Cheung, Nai Kong V, Papaemmanuil, Elli
Published in Clinical cancer research (14.04.2022)
Published in Clinical cancer research (14.04.2022)
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Journal Article
Subclonal somatic copy number alterations emerge and dominate in recurrent osteosarcoma
Kinnaman, Michael D, Zaccaria, Simone, Makohon-Moore, Alvin, Arnold, Brian, Levine, Max, Gundem, Gunes, Ossa, Juan E Arango, Glodzik, Dominik, Rodríguez-Sánchez, M Irene, Bouvier, Nancy, Li, Shanita, Stockfisch, Emily, Dunigan, Marisa, Cobbs, Cassidy, Bhanot, Umesh, You, Daoqi, Mullen, Katelyn, Melchor, Jerry, Ortiz, Michael V, O'Donohue, Tara, Slotkin, Emily, Wexler, Leonard H, Dela Cruz, Filemon S, Hameed, Meera, Glade Bender, Julia L, Tap, William D, Meyers, Paul A, Papaemmanuil, Elli, Kung, Andrew L, Iacobuzio-Donahue, Christine A
Published in bioRxiv (24.01.2023)
Published in bioRxiv (24.01.2023)
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Paper
Diagnostic utility of whole genome sequencing in adults with B-other acute lymphoblastic leukemia
Leongamornlert, Daniel, Gutiérrez-Abril, Jesús, Lee, SooWah, Barretta, Emilio, Creasey, Thomas, Gundem, Gunes, Levine, Max F., Arango-Ossa, Juan E., Liosis, Konstantinos, Medina-Martinez, Juan S., Zuborne Alapi, Krisztina, Kirkwood, Amy A., Clifton-Hadley, Laura, Patrick, Pip, Jones, David, O’Neill, Laura, Butler, Adam P., Harrison, Christine J., Campbell, Peter, Patel, Bela, Moorman, Anthony V., Fielding, Adele K., Papaemmanuil, Elli
Published in Blood advances (08.08.2023)
Published in Blood advances (08.08.2023)
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Journal Article
Cancer therapy shapes the fitness landscape of clonal hematopoiesis
Bolton, Kelly L., Ptashkin, Ryan N., Gao, Teng, Braunstein, Lior, Devlin, Sean M., Kelly, Daniel, Patel, Minal, Berthon, Antonin, Syed, Aijazuddin, Yabe, Mariko, Coombs, Catherine C., Caltabellotta, Nicole M., Walsh, Mike, Offit, Kenneth, Stadler, Zsofia, Mandelker, Diana, Schulman, Jessica, Patel, Akshar, Philip, John, Bernard, Elsa, Gundem, Gunes, Ossa, Juan E. Arango, Levine, Max, Martinez, Juan S. Medina, Farnoud, Noushin, Glodzik, Dominik, Li, Sonya, Robson, Mark E., Lee, Choonsik, Pharoah, Paul D. P., Stopsack, Konrad H., Spitzer, Barbara, Mantha, Simon, Fagin, James, Boucai, Laura, Gibson, Christopher J., Ebert, Benjamin L., Young, Andrew L., Druley, Todd, Takahashi, Koichi, Gillis, Nancy, Ball, Markus, Padron, Eric, Hyman, David M., Baselga, Jose, Norton, Larry, Gardos, Stuart, Klimek, Virginia M., Scher, Howard, Bajorin, Dean, Paraiso, Eder, Benayed, Ryma, Arcila, Maria E., Ladanyi, Marc, Solit, David B., Berger, Michael F., Tallman, Martin, Garcia-Closas, Montserrat, Chatterjee, Nilanjan, Diaz, Luis A., Levine, Ross L., Morton, Lindsay M., Zehir, Ahmet, Papaemmanuil, Elli
Published in Nature genetics (01.11.2020)
Published in Nature genetics (01.11.2020)
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Journal Article
Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes (vol 26, pg 1549, 2020)
Bernard, E, Nannya, Y, Hasserjian, RP, Devlin, SM, Tuechler, H, Medina-Martinez, JS, Yoshizato, T, Shiozawa, Y, Saiki, R, Malcovati, L
Published in NATURE MEDICINE (01.05.2021)
Published in NATURE MEDICINE (01.05.2021)
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Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes (vol 26, pg 1549, 2020)
Bernard, E, Nannya, Y, Hasserjian, RP, Devlin, SM, Tuechler, H, Medina-Martinez, JS, Yoshizato, T, Shiozawa, Y, Saiki, R, Malcovati, L
Published in NATURE MEDICINE (01.03.2021)
Published in NATURE MEDICINE (01.03.2021)
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Abstract 3556: Assessing patterns of genomic instability in recurrent osteosarcoma
Kinnaman, Michael David, Zaccaria, Simone, Makohon-Moore, Alvin, Gundem, Gunes, Ossa, Juan E. Arango, Dela Cruz, Filemon S., Meyers, Paul A., Hameed, Meera, Tap, William D., Bender, Julia Lynne Glade, Papaemmanuil, Elli, Kung, Andrew, Donahue, Christine Iacobuzio
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
Abstract B022: Subclonal somatic copy number alterations emerge and dominate in relapsed/refractory osteosarcoma
Kinnaman, Michael D., Zaccaria, Simone, Makohon-Moore, Alvin, Gundem, Gunes, Ossa, Juan E. Arango, Bouvier, Nancy, Dela Cruz, Filemon S., Hameed, Meera, Bender, Julia Lynne Glade, Tap, William D., Meyers, Paul, Papaemmanuil, Elli, Kung, Andrew, Iacobuzio-Donahue, Christine A.
Published in Clinical cancer research (15.09.2022)
Published in Clinical cancer research (15.09.2022)
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Journal Article
Long-Term Outcome of Patients with Follicular Lymphoma Is Not Fundamentally Affected By KMT2D, EZH2, and Crebbp Mutational Status
Bantilan, Kurt S., Rutherford, Kayleigh, McCarter, Joseph, Farnoud, Noushin, Arango-Ossa, Juan E., Papaemmanuil, Elli, Zelenetz, Andrew D.
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
Abstract 6168: Implementation and adoption of a web tool to support precision diagnostic and treatment decisions for patient with myelodysplastic syndromes
Bernard, Elsa, Ossa, Juan E. Arango, Tuechler, Heinz, Greenberg, Peter L., Hasserjian, Robert P., Nannya, Yasuhito, Devlin, Sean M., Creignou, Maria, Pinel, Philippe, Monier, Lily, Medina-Martinez, Juan S., Domenico, Dylan, Jädersten, Martin, Germing, Ulrich, Sanz, Guillermo, van de Loosdrecht, Arjan A., Kosmider, Olivier, Follo, Matilde Y., Thol, Felicitas, Zamora, Lurdes, Pinheiro, Ronald F., Pellagatti, Andrea, Haase, Detlef, Fenaux, Pierre, Belickova, Monika, Savona, Michael R., Klimek, Virginia M., Santos, Fabio P., Boultwood, Jacqueline, Kotsianidis, Ioannis, Santini, Valeria, Solé, Francesc, Platzbecker, Uwe, Heuser, Michael, Valent, Peter, Ohyashiki, Kazuma, Finelli, Carlo, Voso, Maria Teresa, Shih, Lee-Yung, Fontenay, Michaela, Jansen, Joop H., Cervera, José, Gattermann, Norbert, Ebert, Benjamin L., Bejar, Rafael, Malcovati, Luca, Cazzola, Mario, Ogawa, Seishi, Hellström-Lindberg, Eva, Papaemmanuil, Elli
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
Diagnostic Utility of Comprehensive RNA-Seq Analysis in Adult B-ALL
Farnoud, Noushin, Liosis, Konstantinos, Leongamornlert, Daniel, Gutiérrez-Abril, Jesús, Arango Ossa, Juan E., Gundem, Gunes, Amallraja, Anu, Domenico, Dylan, McCarter, Joseph, Kirkwood, Amy A, Clifton-Hadley, Laura, Patel Wrench, Bela, Moorman, Anthony, Fielding, Adele Kay, Papaemmanuil, Elli
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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