Characterization of In Vitro Resistance to Linezolid in Mycobacterium abscessus
Negatu, Dereje A, Aragaw, Wassihun Wedajo, Dartois, Véronique, Dick, Thomas
Published in Microbiology spectrum (17.08.2023)
Published in Microbiology spectrum (17.08.2023)
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Journal Article
In Vitro Resistance against DNA Gyrase Inhibitor SPR719 in Mycobacterium avium and Mycobacterium abscessus
Aragaw, Wassihun Wedajo, Cotroneo, Nicole, Stokes, Suzanne, Pucci, Michael, Critchley, Ian, Gengenbacher, Martin, Dick, Thomas
Published in Microbiology spectrum (23.02.2022)
Published in Microbiology spectrum (23.02.2022)
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Journal Article
Multidrug tolerance conferred by loss-of-function mutations in anti-sigma factor RshA of Mycobacterium abscessus
Aragaw, Wassihun Wedajo, Gebresilase, Tewodros T, Negatu, Dereje A, Dartois, Véronique, Dick, Thomas
Published in Antimicrobial agents and chemotherapy (29.10.2024)
Published in Antimicrobial agents and chemotherapy (29.10.2024)
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Journal Article
Side-by-Side Profiling of Oxazolidinones to Estimate the Therapeutic Window against Mycobacterial Infections
Negatu, Dereje A, Aragaw, Wassihun Wedajo, Cangialosi, Julianna, Dartois, Véronique, Dick, Thomas
Published in Antimicrobial agents and chemotherapy (18.04.2023)
Published in Antimicrobial agents and chemotherapy (18.04.2023)
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Journal Article
A pairwise approach to revitalize β-lactams for the treatment of TB
Negatu, Dereje A, Aragaw, Wassihun Wedajo, Dartois, Véronique, Dick, Thomas
Published in Antimicrobial agents and chemotherapy (01.05.2024)
Published in Antimicrobial agents and chemotherapy (01.05.2024)
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Journal Article
Cyclohexyl-griselimycin Is Active against Mycobacterium abscessus in Mice
Aragaw, Wassihun Wedajo, Roubert, Christine, Fontaine, Evelyne, Lagrange, Sophie, Zimmerman, Matthew D, Dartois, Véronique, Gengenbacher, Martin, Dick, Thomas
Published in Antimicrobial agents and chemotherapy (18.01.2022)
Published in Antimicrobial agents and chemotherapy (18.01.2022)
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Journal Article
Piperidine-4-Carboxamides Target DNA Gyrase in Mycobacterium abscessus
Negatu, Dereje Abate, Beuchel, Andreas, Madani, Abdeldjalil, Alvarez, Nadine, Chen, Chao, Aragaw, Wassihun Wedajo, Zimmerman, Matthew D, Laleu, Benoît, Gengenbacher, Martin, Dartois, Véronique, Imming, Peter, Dick, Thomas
Published in Antimicrobial agents and chemotherapy (16.07.2021)
Published in Antimicrobial agents and chemotherapy (16.07.2021)
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Journal Article
Synthesis and Characterization of Phenylalanine Amides Active against Mycobacterium abscessus and Other Mycobacteria
Lang, Markus, Ganapathy, Uday S., Mann, Lea, Abdelaziz, Rana, Seidel, Rüdiger W., Goddard, Richard, Sequenzia, Ilaria, Hoenke, Sophie, Schulze, Philipp, Aragaw, Wassihun Wedajo, Csuk, René, Dick, Thomas, Richter, Adrian
Published in Journal of medicinal chemistry (13.04.2023)
Published in Journal of medicinal chemistry (13.04.2023)
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Journal Article
Potency boost of a Mycobacterium tuberculosis dihydrofolate reductase inhibitor by multienzyme F420H₂-dependent reduction
Aragaw, Wassihun Wedajo, Lee, Brendon M., Yang, Xuan, Zimmerman, Matthew D., Gengenbacher, Martin, Dartois, Véronique, Chui, Wai-Keung, Jackson, Colin J., Dick, Thomas
Published in Proceedings of the National Academy of Sciences - PNAS (22.06.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (22.06.2021)
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Journal Article
A Mycobacterium tuberculosis NBTI DNA Gyrase Inhibitor Is Active against Mycobacterium abscessus
Ganapathy, Uday S, Del Río, Rubén González, Cacho-Izquierdo, Mónica, Ortega, Fátima, Lelièvre, Joël, Barros-Aguirre, David, Aragaw, Wassihun Wedajo, Zimmerman, Matthew D, Lindman, Marissa, Dartois, Véronique, Gengenbacher, Martin, Dick, Thomas
Published in Antimicrobial agents and chemotherapy (17.11.2021)
Published in Antimicrobial agents and chemotherapy (17.11.2021)
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Journal Article
Pharmacological validation of dihydrofolate reductase as a drug target in Mycobacterium abscessus
Aragaw, Wassihun Wedajo, Negatu, Dereje A, Bungard, Christopher J, Dartois, Véronique A, Marrouni, Abdellatif El, Nickbarg, Elliott B, Olsen, David B, Warrass, Ralf, Dick, Thomas
Published in Antimicrobial agents and chemotherapy (10.01.2024)
Published in Antimicrobial agents and chemotherapy (10.01.2024)
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Journal Article
A Rabbit Model to Study Antibiotic Penetration at the Site of Infection for Nontuberculous Mycobacterial Lung Disease: Macrolide Case Study
Kaya, Firat, Ernest, Jacqueline P, LoMauro, Katherine, Gengenbacher, Martin, Madani, Abdeldjalil, Aragaw, Wassihun Wedajo, Zimmerman, Matthew D, Sarathy, Jansy P, Alvarez, Nadine, Daudelin, Isaac, Wang, Han, Lanni, Faye, Weiner, Danielle M, Via, Laura E, Barry, 3rd, Clifton E, Olivier, Kenneth N, Dick, Thomas, Podell, Brendan K, Savic, Radojka M, Dartois, Véronique
Published in Antimicrobial agents and chemotherapy (15.03.2022)
Published in Antimicrobial agents and chemotherapy (15.03.2022)
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Journal Article
Potency boost of a Mycobacterium tuberculosis dihydrofolate reductase inhibitor by multienzyme F 420 H 2 -dependent reduction
Aragaw, Wassihun Wedajo, Lee, Brendon M, Yang, Xuan, Zimmerman, Matthew D, Gengenbacher, Martin, Dartois, Véronique, Chui, Wai-Keung, Jackson, Colin J, Dick, Thomas
Published in Proceedings of the National Academy of Sciences - PNAS (22.06.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (22.06.2021)
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Journal Article
Mycobacterium tuberculosis PanD Structure–Function Analysis and Identification of a Potent Pyrazinoic Acid-Derived Enzyme Inhibitor
Ragunathan, Priya, Cole, Malcolm, Latka, Chitra, Aragaw, Wassihun Wedajo, Hegde, Pooja, Shin, Joon, Subramanian Manimekalai, Malathy Sony, Rishikesan, Sankaranarayanan, Aldrich, Courtney C, Dick, Thomas, Grüber, Gerhard
Published in ACS chemical biology (18.06.2021)
Published in ACS chemical biology (18.06.2021)
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Journal Article
Structural and Mechanistic Insights into Mycobacterium abscessus Aspartate Decarboxylase PanD and a Pyrazinoic Acid-Derived Inhibitor
Saw, Wuan-Geok, Leow, Chen Yen, Harikishore, Amaravadhi, Shin, Joon, Cole, Malcolm S., Aragaw, Wassihun Wedajo, Ragunathan, Priya, Hegde, Pooja, Aldrich, Courtney C., Dick, Thomas, Grüber, Gerhard
Published in ACS infectious diseases (08.07.2022)
Published in ACS infectious diseases (08.07.2022)
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