Correction to “Discovery of Nanomolar Melanocortin‑3 Receptor (MC3R)-Selective Small Molecule Pyrrolidine Bis-Cyclic Guanidine Agonist Compounds Via a High Throughput ‘Unbiased’ Screening Campaign”
Doering, Skye R., Freeman, Katie, Debevec, Ginamarie, Geer, Phaedra, Santos, Radleigh G., Lavoi, Travis M., Giulianotti, Marc A., Pinilla, Clemencia, Appel, Jon R., Houghten, Richard A., Ericson, Mark D., Haskell-Luevano, Carrie
Published in Journal of medicinal chemistry (25.05.2023)
Published in Journal of medicinal chemistry (25.05.2023)
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Journal Article
Discovery of Nanomolar Melanocortin‑3 Receptor (MC3R)-Selective Small Molecule Pyrrolidine Bis-Cyclic Guanidine Agonist Compounds Via a High-Throughput “Unbiased” Screening Campaign
Doering, Skye R, Freeman, Katie, Debevec, Ginamarie, Geer, Phaedra, Santos, Radleigh G, Lavoi, Travis M, Giulianotti, Marc A, Pinilla, Clemencia, Appel, Jon R, Houghten, Richard A, Ericson, Mark D, Haskell-Luevano, Carrie
Published in Journal of medicinal chemistry (13.05.2021)
Published in Journal of medicinal chemistry (13.05.2021)
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Journal Article
The Multi-Leu Peptide Inhibitor Discriminates Between PACE4 and Furin And Exhibits Antiproliferative Effects On Prostate Cancer Cells
Levesque, Christine, Fugère, Martin, Kwiatkowska, Anna, Couture, Frédéric, Desjardins, Roxane, Routhier, Sophie, Moussette, Philippe, Prahl, Adam, Lammek, Bernard, Appel, Jon R., Houghten, Richard A., D’Anjou, François, Dory, Yves L., Neugebauer, Witold, Day, Robert
Published in Journal of medicinal chemistry (13.12.2012)
Published in Journal of medicinal chemistry (13.12.2012)
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Occurrence of Viruses and Associated Grain Yields of Paired Symptomatic and Nonsymptomatic Tillers in Kansas Winter Wheat Fields
Rotenberg, Dorith, Bockus, William W, Whitfield, Anna E, Hervey, Kaylee, Baker, Kara D, Ou, Zhining, Laney, Alma G, De Wolf, Erick D, Appel, Jon A
Published in Phytopathology (01.02.2016)
Published in Phytopathology (01.02.2016)
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The mathematics of a successful deconvolution: a quantitative assessment of mixture-based combinatorial libraries screened against two formylpeptide receptors
Santos, Radleigh G, Appel, Jon R, Giulianotti, Marc A, Edwards, Bruce S, Sklar, Larry A, Houghten, Richard A, Pinilla, Clemencia
Published in Molecules (Basel, Switzerland) (30.05.2013)
Published in Molecules (Basel, Switzerland) (30.05.2013)
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Identification of a small molecule that selectively inhibits mouse PC2 over mouse PC1/3: a computational and experimental study
Yongye, Austin B, Vivoli, Mirella, Lindberg, Iris, Appel, Jon R, Houghten, Richard A, Martinez-Mayorga, Karina
Published in PloS one (22.02.2013)
Published in PloS one (22.02.2013)
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Journal Article
Identification of Tetrapeptides from a Mixture Based Positional Scanning Library That Can Restore nM Full Agonist Function of the L106P, I69T, I102S, A219V, C271Y, and C271R Human Melanocortin‑4 Polymorphic Receptors (hMC4Rs)
Haslach, Erica M, Huang, Huisuo, Dirain, Marvin, Debevec, Ginamarie, Geer, Phaedra, Santos, Radleigh G, Giulianotti, Marc A, Pinilla, Clemencia, Appel, Jon R, Doering, Skye R, Walters, Michael A, Houghten, Richard A, Haskell-Luevano, Carrie
Published in Journal of medicinal chemistry (12.06.2014)
Published in Journal of medicinal chemistry (12.06.2014)
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Journal Article
Selective agonists and antagonists of formylpeptide receptors: duplex flow cytometry and mixture-based positional scanning libraries
Pinilla, Clemencia, Edwards, Bruce S, Appel, Jon R, Yates-Gibbins, Tina, Giulianotti, Marc A, Medina-Franco, Jose L, Young, Susan M, Santos, Radleigh G, Sklar, Larry A, Houghten, Richard A
Published in Molecular pharmacology (01.09.2013)
Published in Molecular pharmacology (01.09.2013)
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Journal Article
Discovery of Mixed Pharmacology Melanocortin-3 Agonists and Melanocortin-4 Receptor Tetrapeptide Antagonist Compounds (TACOs) Based on the Sequence Ac-Xaa 1 -Arg-(pI)DPhe-Xaa 4 -NH 2
Doering, Skye R, Freeman, Katie T, Schnell, Sathya M, Haslach, Erica M, Dirain, Marvin, Debevec, Ginamarie, Geer, Phaedra, Santos, Radleigh G, Giulianotti, Marc A, Pinilla, Clemencia, Appel, Jon R, Speth, Robert C, Houghten, Richard A, Haskell-Luevano, Carrie
Published in Journal of medicinal chemistry (25.05.2017)
Published in Journal of medicinal chemistry (25.05.2017)
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Journal Article
Discovery of Mixed Pharmacology Melanocortin‑3 Agonists and Melanocortin‑4 Receptor Tetrapeptide Antagonist Compounds (TACOs) Based on the Sequence Ac-Xaa1‑Arg-(pI)DPhe-Xaa4‑NH2
Doering, Skye R, Freeman, Katie T, Schnell, Sathya M, Haslach, Erica M, Dirain, Marvin, Debevec, Ginamarie, Geer, Phaedra, Santos, Radleigh G, Giulianotti, Marc A, Pinilla, Clemencia, Appel, Jon R, Speth, Robert C, Houghten, Richard A, Haskell-Luevano, Carrie
Published in Journal of medicinal chemistry (25.05.2017)
Published in Journal of medicinal chemistry (25.05.2017)
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Journal Article
GM-CSF production allows the identification of immunoprevalent antigens recognized by human CD4+ T cells following smallpox vaccination
Judkowski, Valeria, Bunying, Alcinette, Ge, Feng, Appel, Jon R, Law, Kingyee, Sharma, Atima, Raja-Gabaglia, Claudia, Norori, Patricia, Santos, Radleigh G, Giulianotti, Marc A, Slifka, Mark K, Douek, Daniel C, Graham, Barney S, Pinilla, Clemencia
Published in PloS one (09.09.2011)
Published in PloS one (09.09.2011)
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Journal Article
Short Polybasic Peptide Sequences Are Potent Inhibitors of PC5/6 and PC7: Use of Positional Scanning-Synthetic Peptide Combinatorial Libraries as a Tool for the Optimization of Inhibitory Sequences
Fugere, Martin, Appel, Jon, Houghten, Richard A, Lindberg, Iris, Day, Robert
Published in Molecular pharmacology (01.01.2007)
Published in Molecular pharmacology (01.01.2007)
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Journal Article
Rapid Scanning Structure–Activity Relationships in Combinatorial Data Sets: Identification of Activity Switches
Medina-Franco, José L, Edwards, Bruce S, Pinilla, Clemencia, Appel, Jon R, Giulianotti, Marc A, Santos, Radleigh G, Yongye, Austin B, Sklar, Larry A, Houghten, Richard A
Published in Journal of chemical information and modeling (24.06.2013)
Published in Journal of chemical information and modeling (24.06.2013)
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Hospital-based comprehensive cardiac rehabilitation versus usual care among patients with congestive heart failure, ischemic heart disease, or high risk of ischemic heart disease: 12-Month results of a randomized clinical trial
Zwisler, Ann-Dorthe Olsen, PhD, Soja, Anne Merete Boas, PhD, Rasmussen, Søren, PhD, Frederiksen, Marianne, MD, Abadini, Sadollah, MD, Appel, Jon, MD, Rasmussen, Hanne, PhD, Gluud, Christian, DMSc, Iversen, Lars, DMSc, Sigurd, Bjarne, MD, Madsen, Mette, MSc, Fischer-Hansen, Jørgen, DMSc
Published in The American heart journal (01.06.2008)
Published in The American heart journal (01.06.2008)
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Journal Article
Polyarginines Are Potent Furin Inhibitors
Cameron, Angus, Appel, Jon, Houghten, Richard A., Lindberg, Iris
Published in The Journal of biological chemistry (24.11.2000)
Published in The Journal of biological chemistry (24.11.2000)
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Journal Article
Tissue-Doppler Assessment of Cardiac Left Ventricular Function during Short-Term Adjuvant Epirubicin Therapy for Breast Cancer
Appel, Jon M., MD, PhD, Sogaard, Peter, MD, DmSc, Mortensen, Christiane E., MD, Skagen, Knud, MD, DmSc, Nielsen, Dorte L., MD, DmSc
Published in Journal of the American Society of Echocardiography (01.02.2011)
Published in Journal of the American Society of Echocardiography (01.02.2011)
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Journal Article
Advances in the use of synthetic combinatorial chemistry: Mixture-based libraries
Houghten, Richard A, Pinilla, Clemencia, Appel, Jon R, Borràs, Eva
Published in Nature medicine (01.01.2003)
Published in Nature medicine (01.01.2003)
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Journal Article
Mixture-Based Synthetic Combinatorial Libraries
Houghten, Richard A, Pinilla, Clemencia, Appel, Jon R, Blondelle, Sylvie E, Dooley, Colette T, Eichler, Jutta, Nefzi, Adel, Ostresh, John M
Published in Journal of medicinal chemistry (23.09.1999)
Published in Journal of medicinal chemistry (23.09.1999)
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Journal Article
Long-term heart function after adjuvant epirubicin chemotherapy for breast cancer
Appel, Jon M., Zerahn, Bo, Møller, Susanne, Christensen, Heidi M., Søgaard, Peter, Ejlertsen, Bent, Fogh-Andersen, Niels, Jensen, Benny V., Nielsen, Dorte L.
Published in Acta oncologica (01.11.2012)
Published in Acta oncologica (01.11.2012)
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