Two novel atypical PKC inhibitors; ACPD and DNDA effectively mitigate cell proliferation and epithelial to mesenchymal transition of metastatic melanoma while inducing apoptosis
Ratnayake, Wishrawana S, Apostolatos, André H, Ostrov, David A, Acevedo-Duncan, Mildred
Published in International journal of oncology (01.11.2017)
Published in International journal of oncology (01.11.2017)
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Journal Article
Preclinical testing of 5-amino-1-((1R,2S,3S,4R)-2,3-dihydroxy-4-methylcyclopentyl)-1H-imidazole-4-carboxamide: a potent protein kinase C-ι inhibitor as a potential prostate carcinoma therapeutic
Apostolatos, André H, Apostolatos, Christopher A, Ratnayake, Wishrawana S, Neuger, Anthony, Sansil, Samer, Bourgeois, Marie, Acevedo-Duncan, Mildred
Published in Anti-cancer drugs (01.01.2019)
Published in Anti-cancer drugs (01.01.2019)
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Journal Article
Insulin Promotes Neuronal Survival via the Alternatively Spliced Protein Kinase CδII Isoform
Apostolatos, André, Song, Shijie, Acosta, Sandra, Peart, Mishka, Watson, James E., Bickford, Paula, Cooper, Denise R., Patel, Niketa A.
Published in The Journal of biological chemistry (16.03.2012)
Published in The Journal of biological chemistry (16.03.2012)
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Journal Article
Cannabis Use: An Uncommon Cause of Hypokalemia-Induced Acute Paralysis
Singh, Angad, Apostolatos, Andre, Iyer, Ajay, Bescobedo, Benny, Middlemas, Melissa
Published in Curēus (Palo Alto, CA) (30.08.2023)
Published in Curēus (Palo Alto, CA) (30.08.2023)
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Journal Article
Control of β-Site Amyloid Precursor Protein-Cleaving Enzyme-1 Expression by Protein Kinase C-λ/ι and Nuclear Factor κ-B
Sajan, Mini P, Leitges, Michael, Park, Colin, Diamond, David M, Wu, Jin, Hansen, Barbara C, Duncan, Mildred A, Apostolatos, Christopher A, Apostolatos, Andre H, Kindy, Mark, Farese, Robert V
Published in Current Alzheimer research (01.01.2021)
Published in Current Alzheimer research (01.01.2021)
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Journal Article
Protein kinase C δ (PKCδ) splice variants modulate apoptosis pathway in 3T3L1 cells during adipogenesis: identification of PKCδII inhibitor
Patel, Rekha, Apostolatos, André, Carter, Gay, Ajmo, Joanne, Gali, Meghanath, Cooper, Denise R, You, Min, Bisht, Kirpal S, Patel, Niketa A
Published in The Journal of biological chemistry (13.09.2013)
Published in The Journal of biological chemistry (13.09.2013)
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Journal Article
Vitamin A Metabolite, All-trans-retinoic Acid, Mediates Alternative Splicing of Protein Kinase C δVIII (PKCδVIII) Isoform via Splicing Factor SC35
Apostolatos, Hercules, Apostolatos, André, Vickers, Timothy, Watson, James E., Song, Shijie, Vale, Fernando, Cooper, Denise R., Sanchez-Ramos, Juan, Patel, Niketa A.
Published in The Journal of biological chemistry (20.08.2010)
Published in The Journal of biological chemistry (20.08.2010)
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Journal Article
Identification of a Novel Antiapoptotic Human Protein Kinase C δ Isoform, PKCδVIII in NT2 Cells
Jiang, Kun, Apostolatos, André H, Ghansah, Tomar, Watson, James E, Vickers, Timothy, Cooper, Denise R, Epling-Burnette, P. K, Patel, Niketa A
Published in Biochemistry (Easton) (15.01.2008)
Published in Biochemistry (Easton) (15.01.2008)
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Journal Article
Inhibition of atypical protein kinase C‑ι effectively reduces the malignancy of prostate cancer cells by downregulating the NF-κB signaling cascade
Apostolatos, André H, Ratnayake, Wishrawana S, Win-Piazza, Hla, Apostolatos, Christopher A, Smalley, Tracess, Kang, Loveleen, Salup, Raoul, Hill, Robert, Acevedo-Duncan, Mildred
Published in International journal of oncology (01.11.2018)
Published in International journal of oncology (01.11.2018)
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Journal Article
Oncogenic PKC-ι activates Vimentin during epithelial-mesenchymal transition in melanoma; a study based on PKC-ι and PKC-ζ specific inhibitors
Ratnayake, Wishrawana S., Apostolatos, Christopher A., Apostolatos, André H., Schutte, Ryan J., Huynh, Monica A., Ostrov, David A., Acevedo-Duncan, Mildred
Published in Cell adhesion & migration (03.09.2018)
Published in Cell adhesion & migration (03.09.2018)
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Journal Article
Abstract 2542: c-Jun and FOXO1 play key roles in the overexpression of oncogenic PKC-ι in human prostate and melanoma cell lines
Apostolatos, Andre H., Ratnayake, Wishrawana S., Islam, Anisul, Apostolatos, Christopher, Smalley, Tracess, Acevedo-Duncan, Mildred
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Abstract 5868: Preclinical testing of 5-amino-1-((1R,2S,3S,4R)-2,3-dihydroxy-4-methylcyclopentyl)-1H-imidazole-4-carboxamide (ICA-1): A potent protein kinase C-ι inhibitor as a potential anticancer drug
Apostolatos, Christopher, Apostolatos, Andre H., Ratnayake, Wishrawana S., Bourgeois, Marie, Acevedo-Duncan, Mildred
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Abstract 2369: Transcription activators that regulate PKC-iota expression and are downstream targets of PKC-iota
Apostolatos, Andre H., Ratnayake, Wishrawana S., Smalley, Tracess, Islam, Anisul, Acevedo-Duncan, Mildred
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Atypical PKC controls β-secretase expression and thereby regulates production of Alzheimer plaque precursor Aβ in brain and insulin receptor degradation in liver
Sajan, Mini P., Braun, Ursula, Leitges, Michael, Park, Colin, Diamond, David M., Wu, Jin, Hansen, Barbara C., Duncan, Mildred Acevedo, Apostolatos, Christopher A., Apostolatos, Andre H., Kindy, Mark, Farese, Robert V.
Published in Metabolism, clinical and experimental (01.03.2020)
Published in Metabolism, clinical and experimental (01.03.2020)
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Journal Article
Analysis of PKC- protein levels in normal and malignant breast tissue subtypes
Smalley, Tracess, Islam, S.M. Anisul, Apostolatos, Christopher, Apostoeatos, Andre, Acevedo-Duncan, Miedred
Published in Oncology letters (01.02.2019)
Published in Oncology letters (01.02.2019)
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Journal Article
The Effect of Cinnamon on Adipogenesis: 2171
Andrade, Christian, Patel, Rekha, Apostolatos, Andre, Amodeo, Donald, Patel, Niketa, Vidyarthi, Gitanjali
Published in The American journal of gastroenterology (01.10.2014)
Published in The American journal of gastroenterology (01.10.2014)
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Journal Article
FOXO1 regulates oncogenic PKC-[iota] expression in melanoma inversely to c-Jun in an autocrine manner via IL-17E and ICAM-1 activation
Ratnayake, Wishrawana S, Apostolatos, Christopher A, Breedy, Sloan, Apostolatos, Andre H, Acevedo-Duncan, Mildred
Published in World Academy of Sciences Journal (01.01.2019)
Published in World Academy of Sciences Journal (01.01.2019)
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Journal Article
Identification of a novel antiapoptotic human protein kinase C delta isoform, PKCdeltaVIII in NT2 cells
Jiang, Kun, Apostolatos, André H, Ghansah, Tomar, Watson, James E, Vickers, Timothy, Cooper, Denise R, Epling-Burnette, P K, Patel, Niketa A
Published in Biochemistry (Easton) (15.01.2008)
Published in Biochemistry (Easton) (15.01.2008)
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