Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein
Oyen, David, Torres, Jonathan L, Aoto, Phillip C, Flores-Garcia, Yevel, Binter, Špela, Pholcharee, Tossapol, Carroll, Sean, Reponen, Sini, Wash, Rachael, Liang, Qi, Lemiale, Franck, Locke, Emily, Bradley, Allan, King, C Richter, Emerling, Daniel, Kellam, Paul, Zavala, Fidel, Ward, Andrew B, Wilson, Ian A
Published in PLoS pathogens (09.03.2020)
Published in PLoS pathogens (09.03.2020)
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Journal Article
Structural analyses of the PKA RIIβ holoenzyme containing the oncogenic DnaJB1-PKAc fusion protein reveal protomer asymmetry and fusion-induced allosteric perturbations in fibrolamellar hepatocellular carcinoma
Lu, Tsan-Wen, Aoto, Phillip C, Weng, Jui-Hung, Nielsen, Cole, Cash, Jennifer N, Hall, James, Zhang, Ping, Simon, Sanford M, Cianfrocco, Michael A, Taylor, Susan S
Published in PLoS biology (01.12.2020)
Published in PLoS biology (01.12.2020)
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Journal Article
LRRK2 dynamics analysis identifies allosteric control of the crosstalk between its catalytic domains
Weng, Jui-Hung, Aoto, Phillip C, Lorenz, Robin, Wu, Jian, Schmidt, Sven H, Manschwetus, Jascha T, Kaila-Sharma, Pallavi, Silletti, Steve, Mathea, Sebastian, Chatterjee, Deep, Knapp, Stefan, Herberg, Friedrich W, Taylor, Susan S
Published in PLoS biology (22.02.2022)
Published in PLoS biology (22.02.2022)
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Journal Article
Defining the Structural Basis for Allosteric Product Release from E. coli Dihydrofolate Reductase Using NMR Relaxation Dispersion
Oyen, David, Fenwick, R. Bryn, Aoto, Phillip C, Stanfield, Robyn L, Wilson, Ian A, Dyson, H. Jane, Wright, Peter E
Published in Journal of the American Chemical Society (16.08.2017)
Published in Journal of the American Chemical Society (16.08.2017)
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Journal Article
Probing the Non-Native H Helix Translocation in Apomyoglobin Folding Intermediates
Aoto, Phillip C, Nishimura, Chiaki, Dyson, H. Jane, Wright, Peter E
Published in Biochemistry (Easton) (17.06.2014)
Published in Biochemistry (Easton) (17.06.2014)
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Journal Article
Calculation of centralities in protein kinase A
Kornev, Alexandr P, Aoto, Phillip C, Taylor, Susan S
Published in Proceedings of the National Academy of Sciences - PNAS (22.11.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (22.11.2022)
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Journal Article
Conformation and dynamics of the kinase domain drive subcellular location and activation of LRRK2
Schmidt, Sven H., Weng, Jui-Hung, Aoto, Phillip C., Boassa, Daniela, Mathea, Sebastian, Silletti, Steve, Hu, Junru, Wallbott, Maximilian, Komives, Elizabeth A., Knapp, Stefan, Herberg, Friedrich W., Taylor, Susan S.
Published in Proceedings of the National Academy of Sciences - PNAS (08.06.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (08.06.2021)
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Journal Article
Molecular‐dynamics simulation methods for macromolecular crystallography
Wych, David C., Aoto, Phillip C., Vu, Lily, Wolff, Alexander M., Mobley, David L., Fraser, James S., Taylor, Susan S., Wall, Michael E.
Published in Acta crystallographica. Section D, Biological crystallography. (01.01.2023)
Published in Acta crystallographica. Section D, Biological crystallography. (01.01.2023)
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Journal Article
Two PKA RIα holoenzyme states define ATP as an isoform-specific orthosteric inhibitor that competes with the allosteric activator, cAMP
Lu, Tsan-Wen, Wu, Jian, Aoto, Phillip C., Weng, Jui-Hung, Ahuja, Lalima G., Sun, Nicholas, Cheng, Cecilia Y., Zhang, Ping, Taylor, Susan S.
Published in Proceedings of the National Academy of Sciences - PNAS (13.08.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (13.08.2019)
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Journal Article
Germline and Mosaic Variants in PRKACA and PRKACB Cause a Multiple Congenital Malformation Syndrome
Palencia-Campos, Adrian, Aoto, Phillip C., Machal, Erik M.F., Rivera-Barahona, Ana, Soto-Bielicka, Patricia, Bertinetti, Daniela, Baker, Blaine, Vu, Lily, Piceci-Sparascio, Francesca, Torrente, Isabella, Boudin, Eveline, Peeters, Silke, Van Hul, Wim, Huber, Celine, Bonneau, Dominique, Hildebrand, Michael S., Coleman, Matthew, Bahlo, Melanie, Bennett, Mark F., Schneider, Amy L., Scheffer, Ingrid E., Kibæk, Maria, Kristiansen, Britta S., Issa, Mahmoud Y., Mehrez, Mennat I., Ismail, Samira, Tenorio, Jair, Li, Gaoyang, Skålhegg, Bjørn Steen, Otaify, Ghada A., Temtamy, Samia, Aglan, Mona, Jønch, Aia E., De Luca, Alessandro, Mortier, Geert, Cormier-Daire, Valérie, Ziegler, Alban, Wallis, Mathew, Lapunzina, Pablo, Herberg, Friedrich W., Taylor, Susan S., Ruiz-Perez, Victor L.
Published in American journal of human genetics (05.11.2020)
Published in American journal of human genetics (05.11.2020)
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Journal Article
A Dynamic Switch in Inactive p38γ Leads to an Excited State on the Pathway to an Active Kinase
Aoto, Phillip C, Stanfield, Robyn L, Wilson, Ian A, Dyson, H. Jane, Wright, Peter E
Published in Biochemistry (Easton) (24.12.2019)
Published in Biochemistry (Easton) (24.12.2019)
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Journal Article
Accurate scoring of non-uniform sampling schemes for quantitative NMR
Aoto, Phillip C., Fenwick, R. Bryn, Kroon, Gerard J.A., Wright, Peter E.
Published in Journal of magnetic resonance (1997) (01.09.2014)
Published in Journal of magnetic resonance (1997) (01.09.2014)
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Journal Article
Broadening cell selection criteria with micropallet arrays of adherent cells
Wang, Yuli, Young, Grace, Aoto, Phillip C, Pai, Jeng-Hao, Bachman, Mark, Li, G.P, Sims, Christopher E, Allbritton, Nancy L
Published in Cytometry. Part A (01.10.2007)
Published in Cytometry. Part A (01.10.2007)
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Journal Article
Structural and Dynamic Effects of Phosphorylation of Protein Kinase a Catalytic Subunit
Vu, Lily, Taylor, Susan S., Aoto, Phillip C., Weng, Jui-Hung
Published in Biophysical journal (07.02.2020)
Published in Biophysical journal (07.02.2020)
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Journal Article
Structural analyses of the PKA RII[beta] holoenzyme containing the oncogenic DnaJB1-PKAc fusion protein reveal protomer asymmetry and fusion-induced allosteric perturbations in fibrolamellar hepatocellular carcinoma
Lu, Tsan-Wen, Aoto, Phillip C, Weng, Jui-Hung, Nielsen, Cole, Cash, Jennifer N, Hall, James, Zhang, Ping, Simon, Sanford M, Cianfrocco, Michael A, Taylor, Susan S, Wijayatilake, Hashi, Alvarez-Garcia, Ines
Published in PLoS biology (28.12.2020)
Published in PLoS biology (28.12.2020)
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Journal Article