Botulinum neurotoxin serotype A specific cell-based potency assay to replace the mouse bioassay
Fernández-Salas, Ester, Wang, Joanne, Molina, Yanira, Nelson, Jeremy B, Jacky, Birgitte P S, Aoki, K Roger
Published in PloS one (21.11.2012)
Published in PloS one (21.11.2012)
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Drug Insight: biological effects of botulinum toxin A in the lower urinary tract
Chancellor, Michael B, Fowler, Clare J, Apostolidis, Apostolos, de Groat, William C, Smith, Christopher P, Somogyi, George T, Roger Aoki, K
Published in Nature clinical practice urology (01.06.2008)
Published in Nature clinical practice urology (01.06.2008)
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The C-terminal heavy-chain domain of botulinum neurotoxin a is not the only site that binds neurons, as the N-terminal heavy-chain domain also plays a very active role in toxin-cell binding and interactions
Ayyar, B Vijayalakshmi, Aoki, K Roger, Atassi, M Zouhair
Published in Infection and immunity (01.04.2015)
Published in Infection and immunity (01.04.2015)
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Identification of fibroblast growth factor receptor 3 (FGFR3) as a protein receptor for botulinum neurotoxin serotype A (BoNT/A)
Jacky, Birgitte P S, Garay, Patton E, Dupuy, Jérôme, Nelson, Jeremy B, Cai, Brian, Molina, Yanira, Wang, Joanne, Steward, Lance E, Broide, Ron S, Francis, Joseph, Aoki, K Roger, Stevens, Raymond C, Fernández-Salas, Ester
Published in PLoS pathogens (2013)
Published in PLoS pathogens (2013)
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A Highly Specific Monoclonal Antibody for Botulinum Neurotoxin Type A-Cleaved SNAP25
Rhéaume, Catherine, Cai, Brian B, Wang, Joanne, Fernández-Salas, Ester, Aoki, K Roger, Francis, Joseph, Broide, Ron S
Published in Toxins (24.06.2015)
Published in Toxins (24.06.2015)
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Evaluation of the therapeutic usefulness of botulinum neurotoxin B, C1, E, and F compared with the long lasting type A. Basis for distinct durations of inhibition of exocytosis in central neurons
Foran, Patrick G, Mohammed, Nadiem, Lisk, Godfrey O, Nagwaney, Sharuna, Lawrence, Gary W, Johnson, Eric, Smith, Leonard, Aoki, K Roger, Dolly, J Oliver
Published in The Journal of biological chemistry (10.01.2003)
Published in The Journal of biological chemistry (10.01.2003)
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Novel Chimeras of Botulinum Neurotoxins A and E Unveil Contributions from the Binding, Translocation, and Protease Domains to Their Functional Characteristics
Wang, Jiafu, Meng, Jianghui, Lawrence, Gary W., Zurawski, Tomas H., Sasse, Astrid, Bodeker, MacDara O., Gilmore, Marcella A., Fernández-Salas, Ester, Francis, Joseph, Steward, Lance E., Aoki, K. Roger, Dolly, J. Oliver
Published in The Journal of biological chemistry (20.06.2008)
Published in The Journal of biological chemistry (20.06.2008)
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Longer-acting and highly potent chimaeric inhibitors of excessive exocytosis created with domains from botulinum neurotoxin A and B
Wang, Jiafu, Zurawski, Tomas H, Bodeker, MacDara O, Meng, Jianghui, Boddul, Sanjay, Aoki, K Roger, Dolly, J Oliver
Published in Biochemical journal (15.05.2012)
Published in Biochemical journal (15.05.2012)
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Depolarization after resonance energy transfer (DARET): A sensitive fluorescence-based assay for botulinum neurotoxin protease activity
Gilmore, Marcella A., Williams, Dudley, Okawa, Yumiko, Holguin, Bret, James, Nicholas G., Ross, Justin A., Roger Aoki, K., Jameson, David M., Steward, Lance E.
Published in Analytical biochemistry (01.06.2011)
Published in Analytical biochemistry (01.06.2011)
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Functional Repair of Motor Endplates after Botulinum Neurotoxin Type A Poisoning: Biphasic Switch of Synaptic Activity between Nerve Sprouts and their Parent Terminals
de Paiva, Anton, Meunier, Frédéric A., Molgó, Jordi, Aoki, K. Roger, Dolly, J. Oliver
Published in Proceedings of the National Academy of Sciences - PNAS (16.03.1999)
Published in Proceedings of the National Academy of Sciences - PNAS (16.03.1999)
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Plasma Membrane Localization Signals in the Light Chain of Botulinum Neurotoxin
Fernández-Salas, Ester, Steward, Lance E., Ho, Helen, Garay, Patton E., Sun, Sarah W., Gilmore, Marcella A., Ordas, Joseph V., Wang, Joanne, Francis, Joseph, Aoki, K. Roger, Boyer, Herbert W.
Published in Proceedings of the National Academy of Sciences - PNAS (02.03.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (02.03.2004)
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