PD-1 derived CA-170 is an oral immune checkpoint inhibitor that exhibits preclinical anti-tumor efficacy
Sasikumar, Pottayil G., Sudarshan, Naremaddepalli S., Adurthi, Srinivas, Ramachandra, Raghuveer K., Samiulla, Dodderi S., Lakshminarasimhan, Anirudha, Ramanathan, Anuradha, Chandrasekhar, Talapaneni, Dhudashiya, Amit A., Talapati, Sumalatha R., Gowda, Nagesh, Palakolanu, Sreenivasulareddy, Mani, Jiju, Srinivasrao, Bandi, Joseph, David, Kumar, Nigam, Nair, Rashmi, Atreya, Hanudatta S., Gowda, Nagaraj, Ramachandra, Murali
Published in Communications biology (08.06.2021)
Published in Communications biology (08.06.2021)
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Discovery of MAP855, an Efficacious and Selective MEK1/2 Inhibitor with an ATP-Competitive Mode of Action
Poddutoori, Ramulu, Aardalen, Kimberly, Aithal, Kiran, Barahagar, Sanjeev Surendranath, Belliappa, Charamanna, Bock, Mark, Chelur, Shekar, Gerken, Andrea, Gopinath, Sreevalsam, Gruenenfelder, Bjoern, Kiffe, Michael, Krishnaswami, Maithreyi, Langowski, John, Madapa, Sudharshan, Narayanan, Kishore, Pandit, Chetan, Panigrahi, Sunil Kumar, Perrone, Mark, Potakamuri, Ravi Kumar, Ramachandra, Murali, Ramanathan, Anuradha, Ramos, Rita, Sager, Emine, Samajdar, Susanta, Subramanya, Hosahalli S, Thimmasandra, Devaraja Seethappa, Venetsanakos, Eleni, Möbitz, Henrik
Published in Journal of medicinal chemistry (10.03.2022)
Published in Journal of medicinal chemistry (10.03.2022)
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Journal Article
3‑Alkoxy-pyrrolo[1,2‑b]pyrazolines as Selective Androgen Receptor Modulators with Ideal Physicochemical Properties for Transdermal Administration
Ullrich, Thomas, Sasmal, Sanjita, Boorgu, Venkatesham, Pasagadi, Srinivasu, Cheera, Srisailam, Rajagopalan, Sujatha, Bhumireddy, Archana, Shashikumar, Dhanya, Chelur, Shekar, Belliappa, Charamanna, Pandit, Chetan, Krishnamurthy, Narasimharao, Mukherjee, Subhendu, Ramanathan, Anuradha, Ghadiyaram, Chakshusmathi, Ramachandra, Murali, Santos, Paulo G, Lagu, Bharat, Bock, Mark G, Perrone, Mark H, Weiler, Sven, Keller, Hansjoerg
Published in Journal of medicinal chemistry (11.09.2014)
Published in Journal of medicinal chemistry (11.09.2014)
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Abstract A72: Novel NAMPT inhibitors for the treatment of Pancreatic cancer
Chikanna, Dinesh, Lakshminarasimhan, Anirudha, Khairnar, Vinayak, Panigrahi, Sunil, Ramanathan, Anuradha, Rao, Narasimha, Narayanan, Kishore, Gopinath, Sreevalsam, Ramachandra, Raghuveer, Chelur, Shekar, Pandit, Chetan, Ramachandra, Murali
Published in Molecular cancer research (01.01.2016)
Published in Molecular cancer research (01.01.2016)
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Abstract 5367: Discovery of dihydro-isoxazole derivatives as novel inhibitors of NAMPT for the treatment of multiple myeloma
Chikkanna, Dinesh, Lakshminarasimhan, Anirudha, Khairnar, Vinayak, panigrahi, Sunil, Ramanathan, Anuradha, Rani, Sumalatha, Rao, Narasimha, S, Karthikeyan, Narayanan, Kishore, Gopinath, Sreevalsam, Ramachandra, Raghuveer, K B, Charamanna, Chelur, Shekar, Pandit, Chetan, Ramachandra, Murali
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Abstract 339: Identification of novel covalent inhibitors of K-Ras G12C that are efficacious in a xenograft model of NSCLC
Satyam, Leena Khare, Chikkanna, Dinesh, G, Aswani K., Khairnar, Vinayak V., Reddy, Sreekanth, Durgaprasad, Vakkapatla, Radhakrishna, Kowju, Panigrahi, Sunil K., Ramanathan, Anuradha, Mahasweta, Kumari, Lakshminarasimhan, Anirudha, K, Narasimha R., R, Vinutha, Gopinath, Sreevalsam, Kumar, Suryakant, Shah, Mubarak H., Ramachandra, Raghuveer, B, Kiran A., Pandit, Chetan, Ramachandra, Murali
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
Discovery of 7-azaindole based anaplastic lymphoma kinase (ALK) inhibitors: Wild type and mutant (L1196M) active compounds with unique binding mode
Gummadi, Venkateshwar Rao, Rajagopalan, Sujatha, Looi, Chung-Yeng, Paydar, Mohammadjavad, Renukappa, Girish Aggunda, Ainan, Bharathi Raja, Krishnamurthy, Narasimha Rao, Panigrahi, Sunil Kumar, Mahasweta, Kumari, Raghuramachandran, Sangeetha, Rajappa, Manoj, Ramanathan, Anuradha, Lakshminarasimhan, Anirudha, Ramachandra, Murali, Wong, Pooi-Fong, Mustafa, Mohammad Rais, Nanduri, Srinivas, Hosahalli, Subramanya
Published in Bioorganic & medicinal chemistry letters (01.09.2013)
Published in Bioorganic & medicinal chemistry letters (01.09.2013)
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Journal Article
Discovery of selective RORγ inverse agonists and demonstration of efficacy in inflammatory disease models
Damarla, Ravi Krishna Babu, Ujjinamatada, Ravi K, Nellore, Kavitha, Dodheri, Samiulla S, Chelur, Shekar, Charamanna, K.B, Mukherjee, Subhendu, Reddy, CH Sandeep, Balasubramanian, Wesley Roy, Rathod, Sanjay B, Lakshminarasimhan, Anirudha, Rao, K Narasimha, Ramanathan, Anuradha, Mahalingam, Natarajan, Girish, AR, Samajdar, Susanta, Pandit, Chetan, Ramachandra, Murali
Published in The Journal of immunology (1950) (01.05.2016)
Published in The Journal of immunology (1950) (01.05.2016)
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Abstract B210: Novel inhibitors of nicotinamide phosphoribosyl transferase and their evaluation in combination with bortezomib
Chikkanna, Dinesh, Lakshminarasimhan, Anirudha, Khairnar, Vinayak, Panigrahi, Sunil, Ramanathan, Anuradha, Satyanandan, Aparna, Rao, Narasimha, Karthikeyan, S, Narayanan, Kishore, Gopinath, Sreevalsam, Ramachandra, Raghuveer, Subramanya, Hosahalli, Pandit, Chetan, Ramachandra, Murali
Published in Molecular cancer therapeutics (01.11.2013)
Published in Molecular cancer therapeutics (01.11.2013)
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Journal Article
Novel inhibitors of nicotinamide phosphoribosyl transferase and their evaluation in combination with bortezomib
Ramachandra, Murali, Lakshminarasimhan, Anirudha, Chikkanna, Dinesh, Khairnar, Vinayak, Panigrahi, Sunil, Ramanathan, Anuradha, Rani, Sumalatha, K, Narasimha Rao, S, Karthikeyan, Narayanan, Kishore, Gopinath, Sreevalsam, Ramachandra, Raghuveer, Hosahalli, Subramanya, Pandit, Chetan
Published in Journal of clinical oncology (20.05.2014)
Published in Journal of clinical oncology (20.05.2014)
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Journal Article
Abstract 5389: Novel inhibitors of nicotinamide phosphoribosyl transferase (NAMPT)
Ramachandra, Murali, Pandit, Chetan, Subramanya, Hosahalli, Chikkanna, Dinesh, Lakshminarasimhan, Anirudha, Khairnar, Vinayak, Panigrahi, Sunil, Ramanathan, Anuradha, Satyanandan, Aparna, Rao, Narasimha, Bera, Arnab, Narayanan, Kishore, Gopinath, Sreevalsam, Ramachandra, Raghuveer
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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Journal Article
Efficacy of selective RAR-related orphan receptor gamma (RORγ) inverse agonists in psoriasis and asthma models (CCR6P.278)
Nellore, Kavitha, Bejugam, Mallesham, Damarla, Ravi Krishna Babu, Hegde, Pragathi, Dodheri, Samiulla, Mukherjee, Subhendu, Rao, Narasimha, Lakshminarasimhan, Anirudha, Ramanathan, Anuradha, Balasubramanian, Wesley, Mattegunta, Suresh Babu, Mahalingam, Natarajan, Samajdar, Susanta, Subramanya, Hosahalli
Published in The Journal of immunology (1950) (01.05.2014)
Published in The Journal of immunology (1950) (01.05.2014)
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Journal Article
Discovery of potent and selective retinoid related orphan receptor gamma (ROR?) inverse agonists for the treatment of Th17 mediated diseases
Kavitha, Nellore, Mallesham, Bejugam, Anuradha, Ramanathan, Subhendu, Mukherjee, Anirudha, Lakshminarasimhan, Samiulla, Dodheri, Narasimha, Rao, Ravi Krishna Babu, Damarla, Susanta, Samajdar, Hosahalli, Subramanya
Published in Frontiers in immunology (2013)
Published in Frontiers in immunology (2013)
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