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Published in Biochimica et biophysica acta (01.11.2013)
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Genetic Variability Overrides the Impact of Parental Cell Type and Determines iPSC Differentiation Potential
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Induced Pluripotent Stem Cells Derived from a CLN5 Patient Manifest Phenotypic Characteristics of Neuronal Ceroid Lipofuscinoses
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Published in International journal of molecular sciences (01.05.2017)
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Published in Proceedings of the National Academy of Sciences - PNAS (06.12.2005)
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Laurila, Pirkka-Pekka, Soronen, Jarkko, Kooijman, Sander, Forsström, Saara, Boon, Mariëtte R, Surakka, Ida, Kaiharju, Essi, Coomans, Claudia P, Van Den Berg, Sjoerd A A, Autio, Anu, Sarin, Antti-Pekka, Kettunen, Johannes, Tikkanen, Emmi, Manninen, Tuula, Metso, Jari, Silvennoinen, Reija, Merikanto, Krista, Ruuth, Maija, Perttilä, Julia, Mäkelä, Anne, Isomi, Ayaka, Tuomainen, Anita M, Tikka, Anna, Ramadan, Usama Abo, Seppälä, Ilkka, Lehtimäki, Terho, Eriksson, Johan, Havulinna, Aki, Jula, Antti, Karhunen, Pekka J, Salomaa, Veikko, Perola, Markus, Ehnholm, Christian, Lee-Rueckert, Miriam, Van Eck, Miranda, Roivainen, Anne, Taskinen, Marja-Riitta, Peltonen, Leena, Mervaala, Eero, Jalanko, Anu, Hohtola, Esa, Olkkonen, Vesa M, Ripatti, Samuli, Kovanen, Petri T, Rensen, Patrick C N, Suomalainen, Anu, Jauhiainen, Matti
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Published in Science translational medicine (27.01.2016)
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Roadmap for a precision-medicine initiative in the Nordic region
Njølstad, Pål Rasmus, Andreassen, Ole Andreas, Brunak, Søren, Børglum, Anders D., Dillner, Joakim, Esko, Tõnu, Franks, Paul W., Freimer, Nelson, Groop, Leif, Heimer, Hakon, Hougaard, David M., Hovig, Eivind, Hveem, Kristian, Jalanko, Anu, Kaprio, Jaakko, Knudsen, Gun Peggy, Melbye, Mads, Metspalu, Andres, Mortensen, Preben Bo, Palmgren, Juni, Palotie, Aarno, Reed, Wenche, Stefánsson, Hreinn, Stitziel, Nathan O., Sullivan, Patrick F., Thorsteinsdóttir, Unnur, Vaudel, Marc, Vuorio, Eero, Werge, Thomas, Stoltenberg, Camilla, Stefánsson, Kári
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Proteomic analysis of the palmitoyl protein thioesterase 1 interactome in SH-SY5Y human neuroblastoma cells
Scifo, Enzo, Szwajda, Agnieszka, Soliymani, Rabah, Pezzini, Francesco, Bianchi, Marzia, Dapkunas, Arvydas, Dębski, Janusz, Uusi-Rauva, Kristiina, Dadlez, Michał, Gingras, Anne-Claude, Tyynelä, Jaana, Simonati, Alessandro, Jalanko, Anu, Baumann, Marc H., Lalowski, Maciej
Published in Journal of proteomics (18.06.2015)
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Advanced Feeder‐Free Generation of Induced Pluripotent Stem Cells Directly From Blood Cells
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Cln5 -deficiency in mice leads to microglial activation, defective myelination and changes in lipid metabolism
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Published in Neurobiology of disease (01.04.2012)
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Selective spatiotemporal patterns of glial activation and neuron loss in the sensory thalamocortical pathways of neuronal ceroid lipofuscinosis 8 mice
Kuronen, Mervi, Lehesjoki, Anna-Elina, Jalanko, Anu, Cooper, Jonathan D, Kopra, Outi
Published in Neurobiology of disease (01.09.2012)
Published in Neurobiology of disease (01.09.2012)
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Deficiency of the INCL protein Ppt1 results in changes in ectopic F1-ATP synthase and altered cholesterol metabolism
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Published in Human molecular genetics (15.05.2008)
Published in Human molecular genetics (15.05.2008)
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Brain gene expression profiles of Cln1 and Cln5 deficient mice unravels common molecular pathways underlying neuronal degeneration in NCL diseases
von Schantz, Carina, Saharinen, Juha, Kopra, Outi, Cooper, Jonathan D, Gentile, Massimiliano, Hovatta, Iiris, Peltonen, Leena, Jalanko, Anu
Published in BMC genomics (28.03.2008)
Published in BMC genomics (28.03.2008)
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Progressive thalamocortical neuron loss in Cln5 deficient mice: Distinct effects in Finnish variant late infantile NCL
von Schantz, Carina, Kielar, Catherine, Hansen, Stine N, Pontikis, Charlie C, Alexander, Noreen A, Kopra, Outi, Jalanko, Anu, Cooper, Jonathan D
Published in Neurobiology of disease (01.05.2009)
Published in Neurobiology of disease (01.05.2009)
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Exacerbated neuronal ceroid lipofuscinosis phenotype in Cln1/5 double-knockout mice
Blom, Tea, Schmiedt, Mia-Lisa, Wong, Andrew M, Kyttälä, Aija, Soronen, Jarkko, Jauhiainen, Matti, Tyynelä, Jaana, Cooper, Jonathan D, Jalanko, Anu
Published in Disease models & mechanisms (01.03.2013)
Published in Disease models & mechanisms (01.03.2013)
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Trim37-deficient mice recapitulate several features of the multi-organ disorder Mulibrey nanism
Kettunen, Kaisa M, Karikoski, Riitta, Hämäläinen, Riikka H, Toivonen, Teija T, Antonenkov, Vasily D, Kulesskaya, Natalia, Voikar, Vootele, Hölttä-Vuori, Maarit, Ikonen, Elina, Sainio, Kirsi, Jalanko, Anu, Karlberg, Susann, Karlberg, Niklas, Lipsanen-Nyman, Marita, Toppari, Jorma, Jauhiainen, Matti, Hiltunen, J Kalervo, Jalanko, Hannu, Lehesjoki, Anna-Elina
Published in Biology open (15.05.2016)
Published in Biology open (15.05.2016)
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Palmitoyl protein thioesterase 1 (Ppt1)-deficient mouse neurons show alterations in cholesterol metabolism and calcium homeostasis prior to synaptic dysfunction
Ahtiainen, Laura, Kolikova, Julia, Mutka, Aino-Liisa, Luiro, Kaisu, Gentile, Massimiliano, Ikonen, Elina, Khiroug, Leonard, Jalanko, Anu, Kopra, Outi
Published in Neurobiology of disease (01.10.2007)
Published in Neurobiology of disease (01.10.2007)
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Quantitative analysis of PPT1 interactome in human neuroblastoma cells
Scifo, Enzo, Szwajda, Agnieszka, Soliymani, Rabah, Pezzini, Francesco, Bianchi, Marzia, Dapkunas, Arvydas, Dębski, Janusz, Uusi-Rauva, Kristiina, Dadlez, Michał, Gingras, Anne-Claude, Tyynelä, Jaana, Simonati, Alessandro, Jalanko, Anu, Baumann, Marc H., Lalowski, Maciej
Published in Data in brief (01.09.2015)
Published in Data in brief (01.09.2015)
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