An oncolytic virus expressing a full-length antibody enhances antitumor innate immune response to glioblastoma
Xu, Bo, Tian, Lei, Chen, Jing, Wang, Jing, Ma, Rui, Dong, Wenjuan, Li, Aimin, Zhang, Jianying, Antonio Chiocca, E., Kaur, Balveen, Feng, Mingye, Caligiuri, Michael A., Yu, Jianhua
Published in Nature communications (08.10.2021)
Published in Nature communications (08.10.2021)
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Advances in local therapy for glioblastoma — taking the fight to the tumour
van Solinge, Thomas S., Nieland, Lisa, Chiocca, E. Antonio, Broekman, Marike L. D.
Published in Nature reviews. Neurology (01.04.2022)
Published in Nature reviews. Neurology (01.04.2022)
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Glial and myeloid heterogeneity in the brain tumour microenvironment
Andersen, Brian M., Faust Akl, Camilo, Wheeler, Michael A., Chiocca, E. Antonio, Reardon, David A., Quintana, Francisco J.
Published in Nature reviews. Cancer (01.12.2021)
Published in Nature reviews. Cancer (01.12.2021)
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Radiation-Induced Targeted Nanoparticle-Based Gene Delivery for Brain Tumor Therapy
Erel-Akbaba, Gulsah, Carvalho, Litia A, Tian, Tian, Zinter, Max, Akbaba, Hasan, Obeid, Pierre J, Chiocca, E. Antonio, Weissleder, Ralph, Kantarci, Ayse Gulten, Tannous, Bakhos A
Published in ACS nano (23.04.2019)
Published in ACS nano (23.04.2019)
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Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions
Wen, Patrick Y, Weller, Michael, Lee, Eudocia Quant, Alexander, Brian M, Barnholtz-Sloan, Jill S, Barthel, Floris P, Batchelor, Tracy T, Bindra, Ranjit S, Chang, Susan M, Chiocca, E Antonio, Cloughesy, Timothy F, DeGroot, John F, Galanis, Evanthia, Gilbert, Mark R, Hegi, Monika E, Horbinski, Craig, Huang, Raymond Y, Lassman, Andrew B, Le Rhun, Emilie, Lim, Michael, Mehta, Minesh P, Mellinghoff, Ingo K, Minniti, Giuseppe, Nathanson, David, Platten, Michael, Preusser, Matthias, Roth, Patrick, Sanson, Marc, Schiff, David, Short, Susan C, Taphoorn, Martin J B, Tonn, Joerg-Christian, Tsang, Jonathan, Verhaak, Roel G W, von Deimling, Andreas, Wick, Wolfgang, Zadeh, Gelareh, Reardon, David A, Aldape, Kenneth D, van den Bent, Martin J
Published in Neuro-oncology (Charlottesville, Va.) (17.08.2020)
Published in Neuro-oncology (Charlottesville, Va.) (17.08.2020)
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Blood-brain-barrier spheroids as an in vitro screening platform for brain-penetrating agents
Cho, Choi-Fong, Wolfe, Justin M., Fadzen, Colin M., Calligaris, David, Hornburg, Kalvis, Chiocca, E. Antonio, Agar, Nathalie Y. R., Pentelute, Bradley L., Lawler, Sean E.
Published in Nature communications (06.06.2017)
Published in Nature communications (06.06.2017)
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The Long Non-coding RNA HIF1A-AS2 Facilitates the Maintenance of Mesenchymal Glioblastoma Stem-like Cells in Hypoxic Niches
Mineo, Marco, Ricklefs, Franz, Rooj, Arun K., Lyons, Shawn M., Ivanov, Pavel, Ansari, Khairul I., Nakano, Ichiro, Chiocca, E. Antonio, Godlewski, Jakub, Bronisz, Agnieszka
Published in Cell reports (Cambridge) (14.06.2016)
Published in Cell reports (Cambridge) (14.06.2016)
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Arming an Oncolytic Herpes Simplex Virus Type 1 with a Single-chain Fragment Variable Antibody against PD-1 for Experimental Glioblastoma Therapy
Passaro, Carmela, Alayo, Quazim, De Laura, Isabella, McNulty, John, Grauwet, Korneel, Ito, Hirotaka, Bhaskaran, Vivek, Mineo, Marco, Lawler, Sean E, Shah, Khalid, Speranza, Maria C, Goins, William, McLaughlin, Eric, Fernandez, Soledad, Reardon, David A, Freeman, Gordon J, Chiocca, E Antonio, Nakashima, Hiroshi
Published in Clinical cancer research (01.01.2019)
Published in Clinical cancer research (01.01.2019)
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The functional synergism of microRNA clustering provides therapeutically relevant epigenetic interference in glioblastoma
Bhaskaran, Vivek, Nowicki, Michal O., Idriss, Mahmoud, Jimenez, Miguel A., Lugli, Gianmarco, Hayes, Josie L., Mahmoud, Ahmad Bakur, Zane, Rachel E., Passaro, Carmela, Ligon, Keith L., Haas-Kogan, Daphne, Bronisz, Agnieszka, Godlewski, Jakub, Lawler, Sean E., Chiocca, E. Antonio, Peruzzi, Pierpaolo
Published in Nature communications (25.01.2019)
Published in Nature communications (25.01.2019)
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Toxicity and Efficacy of a Novel GADD34-expressing Oncolytic HSV-1 for the Treatment of Experimental Glioblastoma
Nakashima, Hiroshi, Nguyen, Tran, Kasai, Kazue, Passaro, Carmela, Ito, Hirotaka, Goins, William F, Shaikh, Imran, Erdelyi, Ronald, Nishihara, Reiko, Nakano, Ichiro, Reardon, David A, Anderson, Ana C, Kuchroo, Vijay, Chiocca, E Antonio
Published in Clinical cancer research (01.06.2018)
Published in Clinical cancer research (01.06.2018)
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NOTCH-Induced MDSC Recruitment after oHSV Virotherapy in CNS Cancer Models Modulates Antitumor Immunotherapy
Otani, Yoshihiro, Yoo, Ji Young, Lewis, Cole T, Chao, Samantha, Swanner, Jessica, Shimizu, Toshihiko, Kang, Jin Muk, Murphy, Sara A, Rivera-Caraballo, Kimberly, Hong, Bangxing, Glorioso, Joseph C, Nakashima, Hiroshi, Lawler, Sean E, Banasavadi-Siddegowda, Yeshavanth, Heiss, John D, Yan, Yuanqing, Pei, Guangsheng, Caligiuri, Michael A, Zhao, Zhongming, Chiocca, E Antonio, Yu, Jianhua, Kaur, Balveen
Published in Clinical cancer research (01.04.2022)
Published in Clinical cancer research (01.04.2022)
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CAR-Engineered NK Cells Targeting Wild-Type EGFR and EGFRvIII Enhance Killing of Glioblastoma and Patient-Derived Glioblastoma Stem Cells
Han, Jianfeng, Chu, Jianhong, Keung Chan, Wing, Zhang, Jianying, Wang, Youwei, Cohen, Justus B., Victor, Aaron, Meisen, Walter H., Kim, Sung-hak, Grandi, Paola, Wang, Qi-En, He, Xiaoming, Nakano, Ichiro, Chiocca, E. Antonio, Glorioso III, Joseph C., Kaur, Balveen, Caligiuri, Michael A., Yu, Jianhua
Published in Scientific reports (09.07.2015)
Published in Scientific reports (09.07.2015)
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Concurrent Dexamethasone Limits the Clinical Benefit of Immune Checkpoint Blockade in Glioblastoma
Iorgulescu, J Bryan, Gokhale, Prafulla C, Speranza, Maria C, Eschle, Benjamin K, Poitras, Michael J, Wilkens, Margaret K, Soroko, Kara M, Chhoeu, Chhayheng, Knott, Aine, Gao, Yan, Lim-Fat, Mary Jane, Baker, Gregory J, Bonal, Dennis M, Nguyen, Quang-Dé, Grant, Gareth R L, Ligon, Keith L, Sorger, Peter K, Chiocca, E Antonio, Anderson, Ana C, Kirschmeier, Paul T, Sharpe, Arlene H, Freeman, Gordon J, Reardon, David A
Published in Clinical cancer research (01.01.2021)
Published in Clinical cancer research (01.01.2021)
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Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal
Godlewski, Jakub, Nowicki, Michal O, Bronisz, Agnieszka, Williams, Shanté, Otsuki, Akihiro, Nuovo, Gerard, Raychaudhury, Abhik, Newton, Herbert B, Chiocca, E Antonio, Lawler, Sean
Published in Cancer research (Chicago, Ill.) (15.11.2008)
Published in Cancer research (Chicago, Ill.) (15.11.2008)
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National Institute of Neurological Disorders and Stroke: current funding status, opportunities, challenges, emerging scientific advances, and recommendations for neurosurgery
Lonser, Russell R, Zipfel, Gregory J, Chiocca, E Antonio
Published in Journal of neurosurgery (01.10.2020)
Published in Journal of neurosurgery (01.10.2020)
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A combinational therapy of EGFR-CAR NK cells and oncolytic herpes simplex virus 1 for breast cancer brain metastases
Chen, Xilin, Han, Jianfeng, Chu, Jianhong, Zhang, Lingling, Zhang, Jianying, Chen, Charlie, Chen, Luxi, Wang, Youwei, Wang, Hongwei, Yi, Long, Elder, J Bradley, Wang, Qi-En, He, Xiaoming, Kaur, Balveen, Chiocca, E Antonio, Yu, Jianhua
Published in Oncotarget (10.05.2016)
Published in Oncotarget (10.05.2016)
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microRNA-7 inhibits the epidermal growth factor receptor and the Akt pathway and is down-regulated in glioblastoma
Kefas, Benjamin, Godlewski, Jakub, Comeau, Laurey, Li, Yunqing, Abounader, Roger, Hawkinson, Michael, Lee, Jeongwu, Fine, Howard, Chiocca, E Antonio, Lawler, Sean, Purow, Benjamin
Published in Cancer research (Chicago, Ill.) (15.05.2008)
Published in Cancer research (Chicago, Ill.) (15.05.2008)
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Extracellular Vesicles Modulate the Glioblastoma Microenvironment via a Tumor Suppression Signaling Network Directed by miR-1
BRONISZ, Agnieszka, YAN WANG, OSTROWSKI, Michael C, HOCHBERG, Fred, WEISSLEDER, Ralph, LAWLER, Sean E, CHIOCCA, E. Antonio, GODLEWSKI, Jakub, NOWICKI, Michal O, PERUZZI, Pierpaolo, ANSARI, Khairul I, OGAWA, Daisuke, BALAJ, Leonora, DE RIENZO, Gianluca, MINEO, Marco, NAKANO, Ichiro
Published in Cancer research (Chicago, Ill.) (01.02.2014)
Published in Cancer research (Chicago, Ill.) (01.02.2014)
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