Comparing the preclinical risk profile of inhalable candidate and potential candidate modified risk tobacco products: A bridging use case
Schlage, Walter K., Titz, Bjoern, Iskandar, Anita, Poussin, Carine, Van der Toorn, Marco, Wong, Ee Tsin, Pratte, Pascal, Maeder, Serge, Schaller, Jean-Pierre, Pospisil, Pavel, Boue, Stephanie, Vuillaume, Grégory, Leroy, Patrice, Martin, Florian, Ivanov, Nikolai V., Peitsch, Manuel C., Hoeng, Julia
Published in Toxicology reports (01.01.2020)
Published in Toxicology reports (01.01.2020)
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On Crowd-verification of Biological Networks
Ansari, Sam, Binder, Jean, Boue, Stephanie, Di Fabio, Anselmo, Hayes, William, Hoeng, Julia, Iskandar, Anita, Kleiman, Robin, Norel, Raquel, O'neel, Bruce, Peitsch, Manuel C., Poussin, Carine, Pratt, Dexter, Rhrissorrakrai, Kahn, Schlage, Walter K., Stolovitzky, Gustavo, Talikka, Marja
Published in Bioinformatics and Biology Insights (01.01.2013)
Published in Bioinformatics and Biology Insights (01.01.2013)
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A meta-analysis of microRNAs expressed in human aerodigestive epithelial cultures and their role as potential biomarkers of exposure response to nicotine-containing products
Sewer, Alain, Zanetti, Filippo, Iskandar, Anita R., Guedj, Emmanuel, Dulize, Remi, Peric, Dariusz, Bornand, David, Mathis, Carole, Martin, Florian, Ivanov, Nikolai V., Peitsch, Manuel C., Hoeng, Julia
Published in Toxicology reports (01.01.2020)
Published in Toxicology reports (01.01.2020)
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Journal Article
Biology-inspired microphysiological systems to advance patient benefit and animal welfare in drug development
Marx, Uwe, Akabane, Takafumi, Andersson, Tommy B, Baker, Elizabeth, Beilmann, Mario, Beken, Sonja, Brendler-Schwaab, Susanne, Cirit, Murat, David, Rhiannon, Dehne, Eva-Maria, Durieux, Isabell, Ewart, Lorna, Fitzpatrick, Suzanne C, Frey, Olivier, Fuchs, Florian, Griffith, Linda G, Hamilton, Geraldine A, Hartung, Thomas, Hoeng, Julia, Hogberg, Helena, Hughes, David J, Ingber, Donald E, Iskandar, Anita, Kanamori, Toshiyuki, Kojima, Hajime, Kuehnl, Jochen, Leist, Marcel, Li, Bo, Loskill, Peter, Mendrick, Donna L, Neumann, Thomas, Pallocca, Giorgia, Rusyn, Ivan, Smirnova, Lena, Steger-Hartmann, Thomas, Tagle, Danilo A, Tonevitsky, Alexander, Tsyb, Sergej, Trapecar, Martin, Van de Water, Bob, Van den Eijnden-van Raaij, Janny, Vulto, Paul, Watanabe, Kengo, Wolf, Armin, Zhou, Xiaobing, Roth, Adrian
Published in ALTEX, alternatives to animal experimentation (01.01.2020)
Published in ALTEX, alternatives to animal experimentation (01.01.2020)
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Journal Article
Case study: the role of mechanistic network models in systems toxicology
Hoeng, Julia, Talikka, Marja, Martin, Florian, Sewer, Alain, Yang, Xiang, Iskandar, Anita, Schlage, Walter K., Peitsch, Manuel C.
Published in Drug discovery today (01.02.2014)
Published in Drug discovery today (01.02.2014)
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Journal Article
Impact of aerosols on liver xenobiotic metabolism: A comparison of two methods of exposure
Bovard, David, Renggli, Kasper, Marescotti, Diego, Sandoz, Antonin, Majeed, Shoaib, Pinard, Lucile, Ferreira, Sandra, Pak, Claudius, Barbier, Anaïs, Beguin, Alexandre, Iskandar, Anita, Frentzel, Stefan, Hoeng, Julia, Peitsch, Manuel C.
Published in Toxicology in vitro (01.03.2022)
Published in Toxicology in vitro (01.03.2022)
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Journal Article
Pathway-based predictive approaches for non-animal assessment of acute inhalation toxicity
Clippinger, Amy J., Allen, David, Behrsing, Holger, BéruBé, Kelly A., Bolger, Michael B., Casey, Warren, DeLorme, Michael, Gaça, Marianna, Gehen, Sean C., Glover, Kyle, Hayden, Patrick, Hinderliter, Paul, Hotchkiss, Jon A., Iskandar, Anita, Keyser, Brian, Luettich, Karsta, Ma-Hock, Lan, Maione, Anna G., Makena, Patrudu, Melbourne, Jodie, Milchak, Lawrence, Ng, Sheung P., Paini, Alicia, Page, Kathryn, Patlewicz, Grace, Prieto, Pilar, Raabe, Hans, Reinke, Emily N., Roper, Clive, Rose, Jane, Sharma, Monita, Spoo, Wayne, Thorne, Peter S., Wilson, Daniel M., Jarabek, Annie M.
Published in Toxicology in vitro (01.10.2018)
Published in Toxicology in vitro (01.10.2018)
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Journal Article
A lung/liver-on-a-chip platform for acute and chronic toxicity studiesElectronic supplementary information (ESI) available. See DOI: 10.1039/c8lc01029c
Bovard, David, Sandoz, Antonin, Luettich, Karsta, Frentzel, Stefan, Iskandar, Anita, Marescotti, Diego, Trivedi, Keyur, Guedj, Emmanuel, Dutertre, Quentin, Peitsch, Manuel C, Hoeng, Julia
Year of Publication 04.12.2018
Year of Publication 04.12.2018
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Journal Article
Alternatives to Animal Use in Risk Assessment of Mixtures
Wallace Hayes, A, Muriana, Arantza, Alzualde, Ainhoa, Fernandez, Dania Bacardi, Iskandar, Anita, Peitsch, Manuel C, Kuczaj, Arkadiusz, Hoeng, Julia
Published in International journal of toxicology (01.03.2020)
Published in International journal of toxicology (01.03.2020)
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Journal Article
β-Cryptoxanthin reduced lung tumor multiplicity and inhibited lung cancer cell motility by down-regulating nicotinic acetylcholine receptor α7 signaling
Iskandar, Anita R., Miao, Benchun, Li, Xinli, Hu, Kang-Quan, Liu, Chun, Wang, Xiang-Dong
Published in Cancer prevention research (Philadelphia, Pa.) (13.09.2016)
Published in Cancer prevention research (Philadelphia, Pa.) (13.09.2016)
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Journal Article
Toxicity of aerosols of nicotine and pyruvic acid (separate and combined) in Sprague-Dawley rats in a 28-day OECD 412 inhalation study and assessment of systems toxicology
Phillips, Blaine, Esposito, Marco, Verbeeck, Jan, Boué, Stéphanie, Iskandar, Anita, Vuillaume, Gregory, Leroy, Patrice, Krishnan, Subash, Kogel, Ulrike, Utan, Aneli, Schlage, Walter K., Bera, Monali, Veljkovic, Emilija, Hoeng, Julia, Peitsch, Manuel C., Vanscheeuwijck, Patrick
Published in Inhalation toxicology (29.07.2015)
Published in Inhalation toxicology (29.07.2015)
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Journal Article
Systems Toxicology meta-analysis: Impact of a candidate modified-risk tobacco product aerosol compared with cigarette smoke on organotypic aerodigestive tract cultures
Iskandar, Anita R., Titz, Bjoern, Sewer, Alain, Leroy, Patrice, Schneider, Thomas, Zanetti, Filippo, Mathis, Carole, Elamin, Ashraf, Frentzel, Stefan, Schlage, Walter, Martin, Florian, Nikolai, Ivanov, Peitsch, Manuel, Hoeng, Julia
Published in Toxicology letters (20.10.2017)
Published in Toxicology letters (20.10.2017)
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Journal Article
Abstract B1-19: Computable cancer hallmarks - The construction of novel computable biological network models reflecting causal mechanisms of cancer hallmarks
Luettich, Karsta, Talikka, Marja, Iskandar, Anita, Szostak, Justyna, Kogel, Ulrike, Schlage, Walter, Xiang, Yang, Ben-Yair, Vered Katz, Rotkopf, Shay, Fields, Brett, Park, Jennifer, Hoeng, Julia, Peitsch, Manuel
Published in Cancer research (Chicago, Ill.) (15.11.2015)
Published in Cancer research (Chicago, Ill.) (15.11.2015)
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Journal Article
Construction of biological networks from unstructured information based on a semi-automated curation workflow
Szostak, Justyna, Ansari, Sam, Madan, Sumit, Fluck, Juliane, Talikka, Marja, Iskandar, Anita, De Leon, Hector, Hofmann-Apitius, Martin, Peitsch, Manuel C, Hoeng, Julia
Published in Database : the journal of biological databases and curation (17.06.2015)
Published in Database : the journal of biological databases and curation (17.06.2015)
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Journal Article
Impact assessment of repeated exposure of organotypic 3D bronchial and nasal tissue culture models to whole cigarette smoke
Kuehn, Diana, Majeed, Shoaib, Guedj, Emmanuel, Dulize, Remi, Baumer, Karine, Iskandar, Anita, Boue, Stephanie, Martin, Florian, Kostadinova, Radina, Mathis, Carole, Ivanov, Nikolai V, Frentzel, Stefan, Hoeng, Julia, Peitsch, Manuel C
Published in Journal of visualized experiments (12.02.2015)
Published in Journal of visualized experiments (12.02.2015)
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Journal Article
A crowd-sourcing approach for the construction of species-specific cell signaling networks
Bilal, Erhan, Sakellaropoulos, Theodore, Melas, Ioannis N, Messinis, Dimitris E, Belcastro, Vincenzo, Rhrissorrakrai, Kahn, Meyer, Pablo, Norel, Raquel, Iskandar, Anita, Blaese, Elise, Rice, John J, Peitsch, Manuel C, Hoeng, Julia, Stolovitzky, Gustavo, Alexopoulos, Leonidas G, Poussin, Carine
Published in Bioinformatics (Oxford, England) (15.02.2015)
Published in Bioinformatics (Oxford, England) (15.02.2015)
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Journal Article
Abstract 1605: α-cryptoxanthin supplementation inhibits the carcinogen-initiated and nicotine-promoted lung carcinogenesis in AJ mice by suppression of AKT activation
Iskandar, Anita R., Liu, Chun, Ernst, Hansgeorg, Choi, Sang-Woon, Ausman, Lynne, Wang, Xiang-Dong
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Journal Article
Transcriptional profiling and targeted proteomics reveals common molecular changes associated with cigarette smoke-induced lung emphysema development in five susceptible mouse strains
Cabanski, Maciej, Fields, Brett, Boue, Stephanie, Boukharov, Natalia, DeLeon, Hector, Dror, Natalie, Geertz, Marcel, Guedj, Emmanuel, Iskandar, Anita, Kogel, Ulrike, Merg, Celine, Peck, Michael J., Poussin, Carine, Schlage, Walter K., Talikka, Marja, Ivanov, Nikolai V., Hoeng, Julia, Peitsch, Manuel C.
Published in Inflammation research (01.07.2015)
Published in Inflammation research (01.07.2015)
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