Updating and further expanding GSK's solvent sustainability guide
Alder, Catherine M, Hayler, John D, Henderson, Richard K, Redman, Aniko M, Shukla, Lena, Shuster, Leanna E, Sneddon, Helen F
Published in Green chemistry : an international journal and green chemistry resource : GC (01.01.2016)
Published in Green chemistry : an international journal and green chemistry resource : GC (01.01.2016)
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Discovery of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidines : Potent inhibitors of the IGF-1R receptor tyrosine kinase
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Published in Bioorganic & medicinal chemistry letters (15.01.2009)
Published in Bioorganic & medicinal chemistry letters (15.01.2009)
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Optimization of a series of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine inhibitors of IGF-1R : Elimination of an acid-mediated decomposition pathway
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Published in Bioorganic & medicinal chemistry letters (15.01.2009)
Published in Bioorganic & medicinal chemistry letters (15.01.2009)
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Discovery and SAR of Novel 2,3-Dihydroimidazo[1,2-c]quinazoline PI3K Inhibitors: Identification of Copanlisib (BAY 80-6946)
Scott, William J., Hentemann, Martin F., Rowley, R. Bruce, Bull, Cathy O., Jenkins, Susan, Bullion, Ann M., Johnson, Jeffrey, Redman, Anikó, Robbins, Arthur H., Esler, William, Fracasso, R. Paul, Garrison, Timothy, Hamilton, Mark, Michels, Martin, Wood, Jill E., Wilkie, Dean P., Xiao, Hong, Levy, Joan, Stasik, Enrico, Liu, Ningshu, Schaefer, Martina, Brands, Michael, Lefranc, Julien
Published in ChemMedChem (19.07.2016)
Published in ChemMedChem (19.07.2016)
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4,5-Disubstituted cis-pyrrolidinones as inhibitors of type II 17β-hydroxysteroid dehydrogenase. Part 3. Identification of lead candidate
Wood, Jill, Bagi, Cedo M., Akuche, Christiana, Bacchiocchi, Antonietta, Baryza, Jeremy, Blue, Marie-Luise, Brennan, Catherine, Campbell, Ann-Marie, Choi, Soongyu, Cook, James H., Conrad, Patricia, Dixon, Brian R., Ehrlich, Paul P., Gane, Todd, Gunn, David, Joe, Ted, Johnson, Jeffrey S., Jordan, Jerold, Kramss, Richard, Liu, Peiying, Levy, Joan, Lowe, Derek B., McAlexander, Ian, Natero, Reina, Redman, Anikó M., Scott, William J., Town, Christopher, Wang, Ming, Wang, Yamin, Zhang, Zhonghua
Published in Bioorganic & medicinal chemistry letters (15.09.2006)
Published in Bioorganic & medicinal chemistry letters (15.09.2006)
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Discovery of a new class of p38 kinase inhibitors
Dumas, Jacques, Sibley, Robert, Riedl, Bernd, Monahan, Mary Katherine, Lee, Wendy, Lowinger, Timothy B, Redman, Anikó M, Johnson, Jeffrey S, Kingery-Wood, Jill, Scott, William J, Smith, Roger A, Bobko, Mark, Schoenleber, Robert, Ranges, Gerald E, Housley, Timothy J, Bhargava, Ajay, Wilhelm, Scott M, Shrikhande, Alka
Published in Bioorganic & medicinal chemistry letters (18.09.2000)
Published in Bioorganic & medicinal chemistry letters (18.09.2000)
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p38 Kinase inhibitors for the treatment of arthritis and osteoporosis: thienyl, furyl, and pyrrolyl ureas
Redman, Anikó M, Johnson, Jeffrey S, Dally, Robert, Swartz, Steve, Wild, Hanno, Paulsen, Holger, Caringal, Yolanda, Gunn, David, Renick, Joel, Osterhout, Martin, Kingery-Wood, Jill, Smith, Roger A, Lee, Wendy, Dumas, Jacques, Wilhelm, Scott M, Housley, Timothy J, Bhargava, Ajay, Ranges, Gerald E, Shrikhande, Alka, Young, Deborah, Bombara, Michael, Scott, William J
Published in Bioorganic & medicinal chemistry letters (08.01.2001)
Published in Bioorganic & medicinal chemistry letters (08.01.2001)
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Journal Article
4,5-Disubstituted cis-pyrrolidinones as inhibitors of type II 17β-hydroxysteroid dehydrogenase. Part 2. SAR
Gunn, David, Akuche, Christiana, Baryza, Jeremy, Blue, Marie-Louise, Brennan, Catherine, Campbell, Ann-Marie, Choi, Soongyu, Cook, James, Conrad, Patricia, Dixon, Brian, Dumas, Jacques, Ehrlich, Paul, Gane, Todd, Joe, Ted, Johnson, Jeffrey, Jordan, Jerold, Kramss, Richard, Liu, Peying, Levy, Joan, Lowe, Derek, McAlexander, Ian, Natero, Reina, Redman, Anikó M., Scott, William, Seng, Thomas, Sibley, Robert, Wang, Ming, Wang, Yamin, Wood, Jill, Zhang, Zhonghua
Published in Bioorganic & medicinal chemistry letters (15.06.2005)
Published in Bioorganic & medicinal chemistry letters (15.06.2005)
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Journal Article
Optimization of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine IGF-1R tyrosine kinase inhibitors towards JNK selectivity
Chamberlain, Stanley D, Redman, Anikó M, Wilson, Joseph W, Deanda, Felix, Shotwell, J Brad, Gerding, Roseanne, Lei, Huangshu, Yang, Bin, Stevens, Kirk L, Hassell, Anne M, Shewchuk, Lisa M, Leesnitzer, M Anthony, Smith, Jeffery L, Sabbatini, Peter, Atkins, Charity, Groy, Arthur, Rowand, Jason L, Kumar, Rakesh, Mook, Jr, Robert A, Moorthy, Ganesh, Patnaik, Samarjit
Published in Bioorganic & medicinal chemistry letters (15.01.2009)
Published in Bioorganic & medicinal chemistry letters (15.01.2009)
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Journal Article
Reversible Carboxamide-Mediated Internal Activation at C(6) of 2-Chloro-4-anilino-1H-pyrrolo[2,3-d]pyrimidines
Chamberlain, Stanley D, Gerding, Roseanne M, Lei, Huangshu, Moorthy, Ganesh, Patnaik, Samarjit, Redman, Anikó M, Stevens, Kirk L, Wilson, Joseph W, Yang, Bin, Shotwell, J. Brad
Published in Journal of organic chemistry (05.12.2008)
Published in Journal of organic chemistry (05.12.2008)
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Synthesis and pharmacological characterization of a potent, orally active p38 kinase inhibitor
Dumas, Jacques, Hatoum-Mokdad, Holia, Sibley, Robert N, Smith, Roger A, Scott, William J, Khire, Uday, Lee, Wendy, Wood, Jill, Wolanin, Donald, Cooley, Jeffrey, Bankston, Donald, Redman, Aniko M, Schoenleber, Robert, Caringal, Yolanda, Gunn, David, Romero, Romulo, Osterhout, Martin, Paulsen, Holger, Housley, Timothy J, Wilhelm, Scott M, Pirro, John, Chien, Du-Shieng, Ranges, Gerald E, Shrikhande, Alka, Muzsi, Andrew, Bortolon, Elizabeth, Wakefield, Jean, Gianpaolo Ostravage, Cynthia, Bhargava, Ajay, Chau, Thuy
Published in Bioorganic & medicinal chemistry letters (17.06.2002)
Published in Bioorganic & medicinal chemistry letters (17.06.2002)
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SAR of a novel ‘Anthranilamide Like’ series of VEGFR-2, multi protein kinase inhibitors for the treatment of cancer
Wickens, Philip, Kluender, Harold, Dixon, Julie, Brennan, Catherine, Achebe, Furahi, Bacchiocchi, Antonella, Bankston, Don, Bierer, Donald, Brands, Michael, Braun, Debbie, Brown, Melissa S., Chuang, Chih-Yuan, Dumas, Jacques, Enyedy, Istvan, Hofilena, Gloria, Hong, Zhenqiu, Housley, Tim, Jones, Benjamin, Khire, Uday, Kreiman, Charles, Kumarasinghe, Ellalahewage, Lowinger, Timothy, Ott-Morgan, Ronda, Perkins, Louise, Phillips, Barton, Schoenleber, Robert, Scott, William J., Sheeler, Ryan, Redman, Anikó, Sun, Xiuying, Taylor, Ian, Wang, Lei, Wilhelm, Scott, Zhang, Xiaomei, Zhang, Mingbao, Sullivan, Elizabeth, Carter, Christopher, Miglarese, Mark, Levy, Joan
Published in Bioorganic & medicinal chemistry letters (01.08.2007)
Published in Bioorganic & medicinal chemistry letters (01.08.2007)
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Journal Article
Optimization of 4,6-bis-anilmo-1H-pyrrolo[2,3-d]pyrimidme IGF-1R tyrosine kinase inhibitors towards JNK selectivity
CHAMBERLAIN, Stanley D, REDMAN, Aniko M, SHEWCHUK, Lisa M, LEESNITZER, M. Anthony, SMITH, Jeffery L, SABBATINI, Peter, ATKINS, Charity, GROY, Arthur, ROWAND, Jason L, KUMAR, Rakesh, MOOK, Robert A, MOORTHY, Ganesh, WILSON, Joseph W, PATNAIK, Samarjit, DEANDA, Felix, SHOTWELL, J. Brad, GERDING, Roseanne, HUANGSHU LEI, BIN YANG, STEVENS, Kirk L, HASSELL, Anne M
Published in Bioorganic & medicinal chemistry letters (2009)
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Published in Bioorganic & medicinal chemistry letters (2009)
Journal Article
Updating and further expanding GSK's solvent sustainability guideElectronic supplementary information (ESI) available. See DOI: 10.1039/c6gc00611f
Alder, Catherine M, Hayler, John D, Henderson, Richard K, Redman, Anikó M, Shukla, Lena, Shuster, Leanna E, Sneddon, Helen F
Year of Publication 27.06.2016
Year of Publication 27.06.2016
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Journal Article
Development of GSK's acid and base selection guidesElectronic supplementary information (ESI) available. See DOI: 10.1039/c4gc01481b
Henderson, Richard K, Hill, Alan P, Redman, Anikó M, Sneddon, Helen F
Year of Publication 09.02.2015
Year of Publication 09.02.2015
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Journal Article
Substituted 2,3-dihydroimidazo[1,2-c]quinazoline derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis
Rowley, Bruce R, Redman, Aniko, Wood, Jill, Campbell, Ann-Marie, Hentemann, Martin, Scott, William, Bullion, Ann-Marie, Michels, Martin
Year of Publication 22.05.2018
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Year of Publication 22.05.2018
Patent
SULFONE SUBSTITUTED 2,3-DIHYDROIMIDAZO Ý1,2-C¨QUINAZOLINE DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS AND DISEASES WITH ANGIOGENESIS
HENTEMANN, Martin, F, SCOTT, William, REDMAN, Aniko, JOHNSON, Jeffrey, WOOD, Jill, GUERNON, Leatte, BULLION, Ann-marie
Year of Publication 18.01.2017
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Year of Publication 18.01.2017
Patent
SUBSTITUTED 2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLINE DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS AND DISEASES ASSOCIATED WITH ANGIOGENESIS
ROWLEY, R., BRUCE, CAMPBELL, ANN-MARIE, BULLION, ANN-MARIE, REDMAN, ANIKO, HENTEMANN, MARTIN, MICHELS, MARTIN, SCOTT, WILLIAM, WOOD, JILL
Year of Publication 29.09.2017
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Year of Publication 29.09.2017
Patent