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High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies
Youn, Ji-Young, Dunham, Wade H., Hong, Seo Jung, Knight, James D.R., Bashkurov, Mikhail, Chen, Ginny I., Bagci, Halil, Rathod, Bhavisha, MacLeod, Graham, Eng, Simon W.M., Angers, Stéphane, Morris, Quaid, Fabian, Marc, Côté, Jean-François, Gingras, Anne-Claude
Published in Molecular cell (01.02.2018)
Published in Molecular cell (01.02.2018)
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Gli proteins in development and disease
Hui, Chi-Chung, Angers, Stephane
Published in Annual review of cell and developmental biology (01.01.2011)
Published in Annual review of cell and developmental biology (01.01.2011)
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Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer
Aubert, Léo, Nandagopal, Neethi, Steinhart, Zachary, Lavoie, Geneviève, Nourreddine, Sami, Berman, Jacob, Saba-El-Leil, Marc K., Papadopoli, David, Lin, Sichun, Hart, Traver, Macleod, Graham, Topisirovic, Ivan, Gaboury, Louis, Fahrni, Christoph J., Schramek, Daniel, Meloche, Sylvain, Angers, Stephane, Roux, Philippe P.
Published in Nature communications (24.07.2020)
Published in Nature communications (24.07.2020)
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High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities
Hart, Traver, Chandrashekhar, Megha, Aregger, Michael, Steinhart, Zachary, Brown, Kevin R., MacLeod, Graham, Mis, Monika, Zimmermann, Michal, Fradet-Turcotte, Amelie, Sun, Song, Mero, Patricia, Dirks, Peter, Sidhu, Sachdev, Roth, Frederick P., Rissland, Olivia S., Durocher, Daniel, Angers, Stephane, Moffat, Jason
Published in Cell (03.12.2015)
Published in Cell (03.12.2015)
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Genome-wide CRISPR screens reveal a Wnt–FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors
Steinhart, Zachary, Pavlovic, Zvezdan, Chandrashekhar, Megha, Hart, Traver, Wang, Xiaowei, Zhang, Xiaoyu, Robitaille, Mélanie, Brown, Kevin R, Jaksani, Sridevi, Overmeer, René, Boj, Sylvia F, Adams, Jarrett, Pan, James, Clevers, Hans, Sidhu, Sachdev, Moffat, Jason, Angers, Stéphane
Published in Nature medicine (01.01.2017)
Published in Nature medicine (01.01.2017)
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Visualization of a short-range Wnt gradient in the intestinal stem-cell niche
Farin, Henner F., Jordens, Ingrid, Mosa, Mohammed H., Basak, Onur, Korving, Jeroen, Tauriello, Daniele V. F., de Punder, Karin, Angers, Stephane, Peters, Peter J., Maurice, Madelon M., Clevers, Hans
Published in Nature (London) (18.02.2016)
Published in Nature (London) (18.02.2016)
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Functional Enhancers Shape Extrachromosomal Oncogene Amplifications
Morton, Andrew R., Dogan-Artun, Nergiz, Faber, Zachary J., MacLeod, Graham, Bartels, Cynthia F., Piazza, Megan S., Allan, Kevin C., Mack, Stephen C., Wang, Xiuxing, Gimple, Ryan C., Wu, Qiulian, Rubin, Brian P., Shetty, Shashirekha, Angers, Stephane, Dirks, Peter B., Sallari, Richard C., Lupien, Mathieu, Rich, Jeremy N., Scacheri, Peter C.
Published in Cell (27.11.2019)
Published in Cell (27.11.2019)
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Three-Dimensional Nanostructured Architectures Enable Efficient Neural Differentiation of Mesenchymal Stem Cells via Mechanotransduction
Poudineh, Mahla, Wang, Zongjie, Labib, Mahmoud, Ahmadi, Moloud, Zhang, Libing, Das, Jagotamoy, Ahmed, Sharif, Angers, Stephane, Kelley, Shana O
Published in Nano letters (14.11.2018)
Published in Nano letters (14.11.2018)
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Identifying chemogenetic interactions from CRISPR screens with drugZ
Colic, Medina, Wang, Gang, Zimmermann, Michal, Mascall, Keith, McLaughlin, Megan, Bertolet, Lori, Lenoir, W. Frank, Moffat, Jason, Angers, Stephane, Durocher, Daniel, Hart, Traver
Published in Genome medicine (22.08.2019)
Published in Genome medicine (22.08.2019)
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Inhibition of Tankyrases Induces Axin Stabilization and Blocks Wnt Signalling in Breast Cancer Cells
Bao, Renyue, Christova, Tania, Song, Siyuan, Angers, Stephane, Yan, Xiaojun, Attisano, Liliana
Published in PloS one (07.11.2012)
Published in PloS one (07.11.2012)
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Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells
MacLeod, Graham, Bozek, Danielle A., Rajakulendran, Nishani, Monteiro, Vernon, Ahmadi, Moloud, Steinhart, Zachary, Kushida, Michelle M., Yu, Helen, Coutinho, Fiona J., Cavalli, Florence M.G., Restall, Ian, Hao, Xiaoguang, Hart, Traver, Luchman, H. Artee, Weiss, Samuel, Dirks, Peter B., Angers, Stephane
Published in Cell reports (Cambridge) (16.04.2019)
Published in Cell reports (Cambridge) (16.04.2019)
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ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells
Park, Nicole I., Guilhamon, Paul, Desai, Kinjal, McAdam, Rochelle F., Langille, Ellen, O’Connor, Madlen, Lan, Xiaoyang, Whetstone, Heather, Coutinho, Fiona J., Vanner, Robert J., Ling, Erick, Prinos, Panagiotis, Lee, Lilian, Selvadurai, Hayden, Atwal, Gurnit, Kushida, Michelle, Clarke, Ian D., Voisin, Veronique, Cusimano, Michael D., Bernstein, Mark, Das, Sunit, Bader, Gary, Arrowsmith, Cheryl H., Angers, Stephane, Huang, Xi, Lupien, Mathieu, Dirks, Peter B.
Published in Cell stem cell (03.08.2017)
Published in Cell stem cell (03.08.2017)
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PRICKLE1 Contributes to Cancer Cell Dissemination through Its Interaction with mTORC2
Daulat, Avais M., Bertucci, François, Audebert, Stéphane, Sergé, Arnauld, Finetti, Pascal, Josselin, Emmanuelle, Castellano, Rémy, Birnbaum, Daniel, Angers, Stéphane, Borg, Jean-Paul
Published in Developmental cell (23.05.2016)
Published in Developmental cell (23.05.2016)
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Molecular architecture and assembly of the DDB1–CUL4A ubiquitin ligase machinery
Angers, Stephane, Li, Ti, Yi, Xianhua, MacCoss, Michael J., Moon, Randall T., Zheng, Ning
Published in Nature (05.10.2006)
Published in Nature (05.10.2006)
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YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation
Fernandez-L, Africa, Northcott, Paul A., Dalton, James, Fraga, Charles, Ellison, David, Angers, Stephane, Taylor, Michael D., Kenney, Anna Marie
Published in Genes & development (01.12.2009)
Published in Genes & development (01.12.2009)
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High-throughput genome-wide phenotypic screening via immunomagnetic cell sorting
Mair, Barbara, Aldridge, Peter M., Atwal, Randy S., Philpott, David, Zhang, Meng, Masud, Sanna N., Labib, Mahmoud, Tong, Amy H. Y., Sargent, Edward H., Angers, Stéphane, Moffat, Jason, Kelley, Shana O.
Published in Nature biomedical engineering (01.10.2019)
Published in Nature biomedical engineering (01.10.2019)
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Tailored tetravalent antibodies potently and specifically activate Wnt/Frizzled pathways in cells, organoids and mice
Tao, Yuyong, Mis, Monika, Blazer, Levi, Ustav, Mart, Steinhart, Zachary, Chidiac, Rony, Kubarakos, Elli, O'Brien, Siobhan, Wang, Xiaomei, Jarvik, Nick, Patel, Nish, Adams, Jarrett, Moffat, Jason, Angers, Stephane, Sidhu, Sachdev S
Published in eLife (27.08.2019)
Published in eLife (27.08.2019)
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ZO-1 interacts with YB-1 in endothelial cells to regulate stress granule formation during angiogenesis
El Bakkouri, Yassine, Chidiac, Rony, Delisle, Chantal, Corriveau, Jeanne, Cagnone, Gael, Gaonac’h-Lovejoy, Vanda, Chin, Ashley, Lécuyer, Éric, Angers, Stephane, Joyal, Jean-Sébastien, Topisirovic, Ivan, Hulea, Laura, Dubrac, Alexandre, Gratton, Jean-Philippe
Published in Nature communications (23.05.2024)
Published in Nature communications (23.05.2024)
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