Resistance of melanoma to immune checkpoint inhibitors is overcome by targeting the sphingosine kinase-1
Imbert, Caroline, Montfort, Anne, Fraisse, Marine, Marcheteau, Elie, Gilhodes, Julia, Martin, Elodie, Bertrand, Florie, Marcellin, Marlène, Burlet-Schiltz, Odile, Peredo, Anne Gonzalez de, Garcia, Virginie, Carpentier, Stéphane, Tartare-Deckert, Sophie, Brousset, Pierre, Rochaix, Philippe, Puisset, Florent, Filleron, Thomas, Meyer, Nicolas, Lamant, Laurence, Levade, Thierry, Ségui, Bruno, Andrieu-Abadie, Nathalie, Colacios, Céline
Published in Nature communications (23.01.2020)
Published in Nature communications (23.01.2020)
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The TNF Paradox in Cancer Progression and Immunotherapy
Montfort, Anne, Colacios, Céline, Levade, Thierry, Andrieu-Abadie, Nathalie, Meyer, Nicolas, Ségui, Bruno
Published in Frontiers in immunology (31.07.2019)
Published in Frontiers in immunology (31.07.2019)
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TNFα blockade overcomes resistance to anti-PD-1 in experimental melanoma
Bertrand, Florie, Montfort, Anne, Marcheteau, Elie, Imbert, Caroline, Gilhodes, Julia, Filleron, Thomas, Rochaix, Philippe, Andrieu-Abadie, Nathalie, Levade, Thierry, Meyer, Nicolas, Colacios, Céline, Ségui, Bruno
Published in Nature communications (22.12.2017)
Published in Nature communications (22.12.2017)
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A fluorogenic substrate for the detection of lipid amidases in intact cells
Casasampere, Mireia, Ung, Johnson, Iñáñez, Alejandro, Dufau, Carine, Tsuboi, Kazuhito, Casas, Josefina, Tan, Su-Fern, Feith, David J., Andrieu-Abadie, Nathalie, Segui, Bruno, Loughran, Thomas P., Abad, José Luis, Fabrias, Gemma
Published in Journal of lipid research (01.03.2024)
Published in Journal of lipid research (01.03.2024)
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Sphingolipid paracrine signaling impairs keratinocyte adhesion to promote melanoma invasion
Noujarède, Justine, Carrié, Lorry, Garcia, Virginie, Grimont, Maxime, Eberhardt, Anaïs, Mucher, Elodie, Genais, Matthieu, Schreuder, Anne, Carpentier, Stéphane, Ségui, Bruno, Nieto, Laurence, Levade, Thierry, Puig, Susana, Torres, Teresa, Malvehy, Josep, Harou, Olivier, Lopez, Jonathan, Dalle, Stéphane, Caramel, Julie, Gibot, Laure, Riond, Joëlle, Andrieu-Abadie, Nathalie
Published in Cell reports (Cambridge) (26.12.2023)
Published in Cell reports (Cambridge) (26.12.2023)
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Ceramide metabolism alterations contribute to Tumor Necrosis Factor-induced melanoma dedifferentiation and predict resistance to immune checkpoint inhibitors in advanced melanoma patients
Dufau, Carine, Genais, Matthieu, Mucher, Elodie, Jung, Benjamin, Garcia, Virginie, Montfort, Anne, Tosolini, Marie, Clarke, Christopher J, Medin, Jeffrey A, Levade, Thierry, Delord, Jean-Pierre, Meyer, Nicolas, Pancaldi, Vera, Andrieu-Abadie, Nathalie, Ségui, Bruno
Published in Frontiers in immunology (29.07.2024)
Published in Frontiers in immunology (29.07.2024)
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Neutral Sphingomyelinase 2 Heightens Anti-Melanoma Immune Responses and Anti-PD-1 Therapy Efficacy
Montfort, Anne, Bertrand, Florie, Rochotte, Julia, Gilhodes, Julia, Filleron, Thomas, Milhès, Jean, Dufau, Carine, Imbert, Caroline, Riond, Joëlle, Tosolini, Marie, Clarke, Christopher J, Dufour, Florent, Constantinescu, Andrei A, Junior, Nilton De França, Garcia, Virginie, Record, Michel, Cordelier, Pierre, Brousset, Pierre, Rochaix, Philippe, Silvente-Poirot, Sandrine, Therville, Nicole, Andrieu-Abadie, Nathalie, Levade, Thierry, Hannun, Yusuf A, Benoist, Hervé, Meyer, Nicolas, Micheau, Olivier, Colacios, Céline, Ségui, Bruno
Published in Cancer immunology research (01.05.2021)
Published in Cancer immunology research (01.05.2021)
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Disruption of sphingosine 1-phosphate lyase confers resistance to chemotherapy and promotes oncogenesis through Bcl-2/Bcl-xL upregulation
Colié, Sandra, Van Veldhoven, Paul P, Kedjouar, Blandine, Bedia, Carmen, Albinet, Virginie, Sorli, Sonia-Caroline, Garcia, Virginie, Djavaheri-Mergny, Mojgan, Bauvy, Chantal, Codogno, Patrice, Levade, Thierry, Andrieu-Abadie, Nathalie
Published in Cancer research (Chicago, Ill.) (15.12.2009)
Published in Cancer research (Chicago, Ill.) (15.12.2009)
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The nonlysosomal β-glucosidase GBA2 promotes endoplasmic reticulum stress and impairs tumorigenicity of human melanoma cells
Sorli, Sonia-Caroline, Colié, Sandra, Albinet, Virginie, Dubrac, Alexandre, Touriol, Christian, Guilbaud, Nicolas, Bedia, Carmen, Fabriàs, Gemma, Casas, Josefina, Ségui, Bruno, Levade, Thierry, Andrieu-Abadie, Nathalie
Published in The FASEB journal (01.02.2013)
Published in The FASEB journal (01.02.2013)
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Sphingomyelin Synthase 1 (SMS1) Downregulation Is Associated With Sphingolipid Reprogramming and a Worse Prognosis in Melanoma
Bilal, Fatima, Montfort, Anne, Gilhodes, Julia, Garcia, Virginie, Riond, Joëlle, Carpentier, Stéphane, Filleron, Thomas, Colacios, Céline, Levade, Thierry, Daher, Ahmad, Meyer, Nicolas, Andrieu-Abadie, Nathalie, Ségui, Bruno
Published in Frontiers in pharmacology (30.04.2019)
Published in Frontiers in pharmacology (30.04.2019)
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Corrigendum: The TNF Paradox in Cancer Progression and Immunotherapy
Montfort, Anne, Colacios, Céline, Levade, Thierry, Andrieu-Abadie, Nathalie, Meyer, Nicolas, Ségui, Bruno
Published in Frontiers in immunology (22.10.2019)
Published in Frontiers in immunology (22.10.2019)
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New Insights into the Role of Sphingolipid Metabolism in Melanoma
Carrié, Lorry, Virazels, Mathieu, Dufau, Carine, Montfort, Anne, Levade, Thierry, Ségui, Bruno, Andrieu-Abadie, Nathalie
Published in Cells (Basel, Switzerland) (26.08.2020)
Published in Cells (Basel, Switzerland) (26.08.2020)
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Sphingolipids as modulators of cancer cell death: Potential therapeutic targets
Ségui, Bruno, Andrieu-Abadie, Nathalie, Jaffrézou, Jean-Pierre, Benoist, Hervé, Levade, Thierry
Published in Biochimica et biophysica acta (01.12.2006)
Published in Biochimica et biophysica acta (01.12.2006)
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Anti-TNF, a magic bullet in cancer immunotherapy?
Montfort, Anne, Dufau, Carine, Colacios, Céline, Andrieu-Abadie, Nathalie, Levade, Thierry, Filleron, Thomas, Delord, Jean-Pierre, Ayyoub, Maha, Meyer, Nicolas, Ségui, Bruno
Published in Journal for immunotherapy of cancer (14.11.2019)
Published in Journal for immunotherapy of cancer (14.11.2019)
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Neutral sphingomyelinase inhibition participates to the benefits of N -acetylcysteine treatment in post-myocardial infarction failing heart rats
Adamy, Christophe, Mulder, Paul, Khouzami, Lara, Andrieu-abadie, Nathalie, Defer, Nicole, Candiani, Gabriele, Pavoine, Catherine, Caramelle, Philippe, Souktani, Richard, Le Corvoisier, Philippe, Perier, Magali, Kirsch, Matthias, Damy, Thibaud, Berdeaux, Alain, Levade, Thierry, Thuillez, Christian, Hittinger, Luc, Pecker, Françoise
Published in Journal of molecular and cellular cardiology (01.09.2007)
Published in Journal of molecular and cellular cardiology (01.09.2007)
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The tricyclodecan-9-yl-xanthogenate D609 triggers ceramide increase and enhances FasL-induced caspase-dependent and -independent cell death in T lymphocytes
Milhas, Delphine, Andrieu-Abadie, Nathalie, Levade, Thierry, Benoist, Hervé, Ségui, Bruno
Published in International journal of molecular sciences (01.07.2012)
Published in International journal of molecular sciences (01.07.2012)
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