Allosteric Activation of Functionally Asymmetric RAF Kinase Dimers
Hu, Jiancheng, Stites, Edward C., Yu, Haiyang, Germino, Elizabeth A., Meharena, Hiruy S., Stork, Philip J.S., Kornev, Alexandr P., Taylor, Susan S., Shaw, Andrey S.
Published in Cell (29.08.2013)
Published in Cell (29.08.2013)
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Single-Cell Transcriptome Profiling of the Kidney Glomerulus Identifies Key Cell Types and Reactions to Injury
Chung, Jun-Jae, Goldstein, Leonard, Chen, Ying-Jiun J, Lee, Jiyeon, Webster, Joshua D, Roose-Girma, Merone, Paudyal, Sharad C, Modrusan, Zora, Dey, Anwesha, Shaw, Andrey S
Published in Journal of the American Society of Nephrology (01.10.2020)
Published in Journal of the American Society of Nephrology (01.10.2020)
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Podocyte Aging: Why and How Getting Old Matters
Shankland, Stuart J, Wang, Yuliang, Shaw, Andrey S, Vaughan, Joshua C, Pippin, Jeffrey W, Wessely, Oliver
Published in Journal of the American Society of Nephrology (01.11.2021)
Published in Journal of the American Society of Nephrology (01.11.2021)
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Disruption of XIAP-RIP2 Association Blocks NOD2-Mediated Inflammatory Signaling
Goncharov, Tatiana, Hedayati, Stefanie, Mulvihill, Melinda M., Izrael-Tomasevic, Anita, Zobel, Kerry, Jeet, Surinder, Fedorova, Anna V., Eidenschenk, Celine, deVoss, Jason, Yu, Kebing, Shaw, Andrey S., Kirkpatrick, Donald S., Fairbrother, Wayne J., Deshayes, Kurt, Vucic, Domagoj
Published in Molecular cell (15.02.2018)
Published in Molecular cell (15.02.2018)
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Activation Mechanism of Oncogenic Deletion Mutations in BRAF, EGFR, and HER2
Foster, Scott A., Whalen, Daniel M., Özen, Ayşegül, Wongchenko, Matthew J., Yin, JianPing, Yen, Ivana, Schaefer, Gabriele, Mayfield, John D., Chmielecki, Juliann, Stephens, Philip J., Albacker, Lee A., Yan, Yibing, Song, Kyung, Hatzivassiliou, Georgia, Eigenbrot, Charles, Yu, Christine, Shaw, Andrey S., Manning, Gerard, Skelton, Nicholas J., Hymowitz, Sarah G., Malek, Shiva
Published in Cancer cell (11.04.2016)
Published in Cancer cell (11.04.2016)
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An Nfil3–Zeb2–Id2 pathway imposes Irf8 enhancer switching during cDC1 development
Bagadia, Prachi, Huang, Xiao, Liu, Tian-Tian, Durai, Vivek, Grajales-Reyes, Gary E., Nitschké, Maximilian, Modrusan, Zora, Granja, Jeffrey M., Satpathy, Ansuman T., Briseño, Carlos G., Gargaro, Marco, Iwata, Arifumi, Kim, Sunkyung, Chang, Howard Y., Shaw, Andrey S., Murphy, Theresa L., Murphy, Kenneth M.
Published in Nature immunology (01.09.2019)
Published in Nature immunology (01.09.2019)
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Bone Marrow Stromal Cell Antigen 2 Is a Specific Marker of Type I IFN-Producing Cells in the Naive Mouse, but a Promiscuous Cell Surface Antigen following IFN Stimulation
Blasius, Amanda L, Giurisato, Emanuele, Cella, Marina, Schreiber, Robert D, Shaw, Andrey S, Colonna, Marco
Published in Journal of Immunology (01.09.2006)
Published in Journal of Immunology (01.09.2006)
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Intravital and Kidney Slice Imaging of Podocyte Membrane Dynamics
Brähler, Sebastian, Yu, Haiyang, Suleiman, Hani, Krishnan, Gokul M, Saunders, Brian T, Kopp, Jeffrey B, Miner, Jeffrey H, Zinselmeyer, Bernd H, Shaw, Andrey S
Published in Journal of the American Society of Nephrology (01.11.2016)
Published in Journal of the American Society of Nephrology (01.11.2016)
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Nanoscale protein architecture of the kidney glomerular basement membrane
Suleiman, Hani, Zhang, Lei, Roth, Robyn, Heuser, John E, Miner, Jeffrey H, Shaw, Andrey S, Dani, Adish
Published in eLife (08.10.2013)
Published in eLife (08.10.2013)
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i-shaped antibody engineering enables conformational tuning of biotherapeutic receptor agonists
Romei, Matthew G., Leonard, Brandon, Katz, Zachary B., Le, Daniel, Yang, Yanli, Day, Eric S., Koo, Christopher W., Sharma, Preeti, Bevers III, Jack, Kim, Ingrid, Dai, Huiguang, Farahi, Farzam, Lin, May, Shaw, Andrey S., Nakamura, Gerald, Sockolosky, Jonathan T., Lazar, Greg A.
Published in Nature communications (20.01.2024)
Published in Nature communications (20.01.2024)
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Albumin-associated free fatty acids induce macropinocytosis in podocytes
Chung, Jun-Jae, Huber, Tobias B, Gödel, Markus, Jarad, George, Hartleben, Björn, Kwoh, Christopher, Keil, Alexander, Karpitskiy, Aleksey, Hu, Jiancheng, Huh, Christine J, Cella, Marina, Gross, Richard W, Miner, Jeffrey H, Shaw, Andrey S
Published in The Journal of clinical investigation (01.06.2015)
Published in The Journal of clinical investigation (01.06.2015)
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Induction of a distinct macrophage population and protection from lung injury and fibrosis by Notch2 blockade
Cruz Tleugabulova, Mayra, Melo, Sandra P., Wong, Aaron, Arlantico, Alexander, Liu, Meizi, Webster, Joshua D., Lau, Julia, Lechner, Antonie, Corak, Basak, Hodgins, Jonathan J., Garlapati, Venkata S., De Simone, Marco, Korin, Ben, Avraham, Shimrit, Lund, Jessica, Jeet, Surinder, Reiss, Alexander, Bender, Hannah, Austin, Cary D., Darmanis, Spyros, Modrusan, Zora, Brightbill, Hans, Durinck, Steffen, Diamond, Michael S., Schneider, Christoph, Shaw, Andrey S., Nitschké, Maximilian
Published in Nature communications (06.11.2024)
Published in Nature communications (06.11.2024)
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The FERM protein EPB41L5 regulates actomyosin contractility and focal adhesion formation to maintain the kidney filtration barrier
Schell, Christoph, Rogg, Manuel, Suhm, Martina, Helmstädter, Martin, Sellung, Dominik, Yasuda-Yamahara, Mako, Kretz, Oliver, Küttner, Victoria, Suleiman, Hani, Kollipara, Laxmikanth, Zahedi, René P., Sickmann, Albert, Eimer, Stefan, Shaw, Andrey S., Kramer-Zucker, Albrecht, Hirano-Kobayashi, Mariko, Abe, Takaya, Aizawa, Shinichi, Grahammer, Florian, Hartleben, Björn, Dengjel, Jörn, Huber, Tobias B.
Published in Proceedings of the National Academy of Sciences - PNAS (06.06.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (06.06.2017)
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Mutation that blocks ATP binding creates a pseudokinase stabilizing the scaffolding function of kinase suppressor of Ras, CRAF and BRAF
Hu, Jiancheng, Yu, Haiyang, Kornev, Alexandr P, Zhao, Jianping, Filbert, Erin L, Taylor, Susan S, Shaw, Andrey S
Published in Proceedings of the National Academy of Sciences - PNAS (12.04.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (12.04.2011)
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Podocytes use FcRn to clear IgG from the glomerular basement membrane
Akilesh, Shreeram, Huber, Tobias B, Wu, Hui, Wang, Gary, Hartleben, Björn, Kopp, Jeffrey B, Miner, Jeffrey H, Roopenian, Derry C, Unanue, Emil R, Shaw, Andrey S
Published in Proceedings of the National Academy of Sciences - PNAS (22.01.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (22.01.2008)
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Antibody toolkit reveals N-terminally ubiquitinated substrates of UBE2W
Davies, Christopher W., Vidal, Simon E., Phu, Lilian, Sudhamsu, Jawahar, Hinkle, Trent B., Chan Rosenberg, Scott, Schumacher, Frances-Rose, Zeng, Yi Jimmy, Schwerdtfeger, Carsten, Peterson, Andrew S., Lill, Jennie R., Rose, Christopher M., Shaw, Andrey S., Wertz, Ingrid E., Kirkpatrick, Donald S., Koerber, James T.
Published in Nature communications (29.07.2021)
Published in Nature communications (29.07.2021)
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