Unraveling the Gentamicin Drug Product Complexity Reveals Variation in Microbiological Activities and Nephrotoxicity
Bulman, Zackery P, Cirz, Ryan, Hildebrandt, Darin, Kane, Tim, Rosario, Zuelay, Wlasichuk, Ken, Park, Minjong, Andrews, Logan D
Published in Antimicrobial agents and chemotherapy (20.08.2020)
Published in Antimicrobial agents and chemotherapy (20.08.2020)
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Journal Article
Probing the Origins of Catalytic Discrimination between Phosphate and Sulfate Monoester Hydrolysis: Comparative Analysis of Alkaline Phosphatase and Protein Tyrosine Phosphatases
Andrews, Logan D, Zalatan, Jesse G, Herschlag, Daniel
Published in Biochemistry (Easton) (04.11.2014)
Published in Biochemistry (Easton) (04.11.2014)
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Journal Article
Tungstate as a Transition State Analog for Catalysis by Alkaline Phosphatase
Peck, Ariana, Sunden, Fanny, Andrews, Logan D., Pande, Vijay S., Herschlag, Daniel
Published in Journal of molecular biology (03.07.2016)
Published in Journal of molecular biology (03.07.2016)
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Journal Article
Potent LpxC Inhibitors with In Vitro Activity against Multidrug-Resistant Pseudomonas aeruginosa
Krause, Kevin M, Haglund, Cat M, Hebner, Christy, Serio, Alisa W, Lee, Grace, Nieto, Vincent, Cohen, Frederick, Kane, Timothy R, Machajewski, Timothy D, Hildebrandt, Darrin, Pillar, Chris, Thwaites, Mary, Hall, Danielle, Miesel, Lynn, Hackel, Meredith, Burek, Amanda, Andrews, Logan D, Armstrong, Eliana, Swem, Lee, Jubb, Adrian, Cirz, Ryan T
Published in Antimicrobial agents and chemotherapy (01.11.2019)
Published in Antimicrobial agents and chemotherapy (01.11.2019)
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Journal Article
Optimization and Mechanistic Characterization of Pyridopyrimidine Inhibitors of Bacterial Biotin Carboxylase
Andrews, Logan D, Kane, Timothy R, Dozzo, Paola, Haglund, Cat M, Hilderbrandt, Darin J, Linsell, Martin S, Machajewski, Timothy, McEnroe, Glen, Serio, Alisa W, Wlasichuk, Kenneth B, Neau, David B, Pakhomova, Svetlana, Waldrop, Grover L, Sharp, Marc, Pogliano, Joe, Cirz, Ryan T, Cohen, Frederick
Published in Journal of medicinal chemistry (22.08.2019)
Published in Journal of medicinal chemistry (22.08.2019)
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Journal Article
Influence of the α-Methoxy Group on the Reaction of Temocillin with Pseudomonas aeruginosa PBP3 and CTX-M-14 β-Lactamase
Sacco, Michael D, Kroeck, Kyle G, Kemp, M Trent, Zhang, Xiujun, Andrews, Logan D, Chen, Yu
Published in Antimicrobial agents and chemotherapy (20.12.2019)
Published in Antimicrobial agents and chemotherapy (20.12.2019)
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Journal Article
Discovery of dual-activity small-molecule ligands of Pseudomonas aeruginosa LpxA and LpxD using SPR and X-ray crystallography
Kroeck, Kyle G., Sacco, Michael D., Smith, Emmanuel W., Zhang, Xiujun, Shoun, Daniel, Akhtar, Afroza, Darch, Sophie E., Cohen, Frederick, Andrews, Logan D., Knox, John E., Chen, Yu
Published in Scientific reports (29.10.2019)
Published in Scientific reports (29.10.2019)
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Journal Article
Optimization of LpxC Inhibitors for Antibacterial Activity and Cardiovascular Safety
Cohen, Frederick, Aggen, James B., Andrews, Logan D., Assar, Zahra, Boggs, Jen, Choi, Taylor, Dozzo, Paola, Easterday, Ashton N., Haglund, Cat M., Hildebrandt, Darin J., Holt, Melissa C., Joly, Kristin, Jubb, Adrian, Kamal, Zeeshan, Kane, Timothy R., Konradi, Andrei W., Krause, Kevin M., Linsell, Martin S., Machajewski, Timothy D., Miroshnikova, Olga, Moser, Heinz E., Nieto, Vincent, Phan, Thu, Plato, Craig, Serio, Alisa W., Seroogy, Julie, Shakhmin, Anton, Stein, Adam J., Sun, Alex D., Sviridov, Serguei, Wang, Zhan, Wlasichuk, Kenneth, Yang, Wen, Zhou, Xiaoming, Zhu, Hai, Cirz, Ryan T.
Published in ChemMedChem (20.08.2019)
Published in ChemMedChem (20.08.2019)
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Journal Article
Structures of Pseudomonas aeruginosa LpxA Reveal the Basis for Its Substrate Selectivity
Smith, Emmanuel W, Zhang, XiuJun, Behzadi, Cyrus, Andrews, Logan D, Cohen, Frederick, Chen, Yu
Published in Biochemistry (Easton) (29.09.2015)
Published in Biochemistry (Easton) (29.09.2015)
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Journal Article