The Impact of Hypoxia on Neutrophil Degranulation and Consequences for the Host
Lodge, Katharine M, Cowburn, Andrew S, Li, Wei, Condliffe, Alison M
Published in International journal of molecular sciences (11.02.2020)
Published in International journal of molecular sciences (11.02.2020)
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HIF-1α-PDK1 axis-induced active glycolysis plays an essential role in macrophage migratory capacity
Semba, Hiroaki, Takeda, Norihiko, Isagawa, Takayuki, Sugiura, Yuki, Honda, Kurara, Wake, Masaki, Miyazawa, Hidenobu, Yamaguchi, Yoshifumi, Miura, Masayuki, Jenkins, Dana M R, Choi, Hyunsung, Kim, Jung-Whan, Asagiri, Masataka, Cowburn, Andrew S, Abe, Hajime, Soma, Katsura, Koyama, Katsuhiro, Katoh, Manami, Sayama, Keimon, Goda, Nobuhito, Johnson, Randall S, Manabe, Ichiro, Nagai, Ryozo, Komuro, Issei
Published in Nature communications (18.05.2016)
Published in Nature communications (18.05.2016)
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Caveolae protect endothelial cells from membrane rupture during increased cardiac output
Cheng, Jade P X, Mendoza-Topaz, Carolina, Howard, Gillian, Chadwick, Jessica, Shvets, Elena, Cowburn, Andrew S, Dunmore, Benjamin J, Crosby, Alexi, Morrell, Nicholas W, Nichols, Benjamin J
Published in The Journal of cell biology (12.10.2015)
Published in The Journal of cell biology (12.10.2015)
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HIF-2α is essential for carotid body development and function
Macias, David, Cowburn, Andrew S, Torres-Torrelo, Hortensia, Ortega-Sáenz, Patricia, López-Barneo, José, Johnson, Randall S
Published in eLife (19.04.2018)
Published in eLife (19.04.2018)
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Hypoxia selectively inhibits respiratory burst activity and killing of Staphylococcus aureus in human neutrophils
McGovern, Naomi N, Cowburn, Andrew S, Porter, Linsey, Walmsley, Sarah R, Summers, Charlotte, Thompson, Alfred A R, Anwar, Sadia, Willcocks, Lisa C, Whyte, Moira K B, Condliffe, Alison M, Chilvers, Edwin R
Published in The Journal of immunology (1950) (01.01.2011)
Published in The Journal of immunology (1950) (01.01.2011)
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Cardiovascular adaptation to hypoxia and the role of peripheral resistance
Cowburn, Andrew S, Macias, David, Summers, Charlotte, Chilvers, Edwin R, Johnson, Randall S
Published in eLife (19.10.2017)
Published in eLife (19.10.2017)
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HIF isoforms in the skin differentially regulate systemic arterial pressure
Cowburn, Andrew S., Takeda, Norihiko, Boutin, Adam T., Kim, Jung-Whan, Sterling, Jane C., Nakasaki, Manando, Southwood, Mark, Goldrath, Ananda W., Jamora, Colin, Nizet, Victor, Chilvers, Edwin R., Johnson, Randall S.
Published in Proceedings of the National Academy of Sciences - PNAS (22.10.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (22.10.2013)
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Functional redundancy of class I phosphoinositide 3-kinase (PI3K) isoforms in signaling growth factor-mediated human neutrophil survival
Juss, Jatinder K, Hayhoe, Richard P, Owen, Charles E, Bruce, Ian, Walmsley, Sarah R, Cowburn, Andrew S, Kulkarni, Suhasini, Boyle, Keith B, Stephens, Len, Hawkins, Phillip T, Chilvers, Edwin R, Condliffe, Alison M
Published in PloS one (24.09.2012)
Published in PloS one (24.09.2012)
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Human Cytomegalovirus Delays Neutrophil Apoptosis and Stimulates the Release of a Prosurvival Secretome
Pocock, Joanna M, Storisteanu, Daniel M L, Reeves, Matthew B, Juss, Jatinder K, Wills, Mark R, Cowburn, Andrew S, Chilvers, Edwin R
Published in Frontiers in immunology (25.09.2017)
Published in Frontiers in immunology (25.09.2017)
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Endothelial cell regulation of systemic haemodynamics and metabolism acts through the HIF transcription factors
Lambden, Simon, Cowburn, Andrew S., Macias, David, Garrud, Tessa A. C., Krause, Bernardo J., Giussani, Dino A., Summers, Charlotte, Johnson, Randall S.
Published in Intensive care medicine experimental (11.06.2021)
Published in Intensive care medicine experimental (11.06.2021)
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Evasion of Neutrophil Extracellular Traps by Respiratory Pathogens
Storisteanu, Daniel M L, Pocock, Joanna M, Cowburn, Andrew S, Juss, Jatinder K, Nadesalingam, Angalee, Nizet, Victor, Chilvers, Edwin R
Published in American journal of respiratory cell and molecular biology (01.04.2017)
Published in American journal of respiratory cell and molecular biology (01.04.2017)
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Changes in helper lymphocyte chemokine receptor expression and elevation of IP-10 during acute respiratory syncytial virus infection in infants
Roe, Michael F. E., Bloxham, David M., Cowburn, Andrew S., O'Donnell, Diarmuid R.
Published in Pediatric allergy and immunology (01.03.2011)
Published in Pediatric allergy and immunology (01.03.2011)
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Eotaxin-1/CC Chemokine Ligand 11: A Novel Eosinophil Survival Factor Secreted by Human Pulmonary Artery Endothelial Cells
Farahi, Neda, Cowburn, Andrew S, Upton, Paul D, Deighton, John, Sobolewski, Anastasia, Gherardi, Ermanno, Morrell, Nicholas W, Chilvers, Edwin R
Published in Journal of Immunology (15.07.2007)
Published in Journal of Immunology (15.07.2007)
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HIF2α–arginase axis is essential for the development of pulmonary hypertension
Cowburn, Andrew S., Crosby, Alexi, Macias, David, Branco, Cristina, Colaço, Renato D. D. R., Southwood, Mark, Toshner, Mark, Alexander, Laura E. Crotty, Morrell, Nicholas W., Chilvers, Edwin R., Johnson, Randall S.
Published in Proceedings of the National Academy of Sciences - PNAS (02.08.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (02.08.2016)
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Involvement of a ferroprotein sensor in hypoxia-mediated inhibition of neutrophil apoptosis
Mecklenburgh, Katy I., Walmsley, Sarah R., Cowburn, Andrew S., Wiesener, Michael, Reed, Benjamin J., Upton, Paul D., Deighton, John, Greening, Andrew P., Chilvers, Edwin R.
Published in Blood (15.10.2002)
Published in Blood (15.10.2002)
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Targeting HIF2α-ARNT hetero-dimerisation as a novel therapeutic strategy for pulmonary arterial hypertension
Macias, David, Moore, Stephen, Crosby, Alexi, Southwood, Mark, Du, Xinlin, Tan, Huiling, Xie, Shanhai, Vassallo, Arlette, Wood, Alexander J T, Wallace, Eli M, Cowburn, Andrew S
Published in The European respiratory journal (01.03.2021)
Published in The European respiratory journal (01.03.2021)
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Journal Article
Hypoxia Increases the Potential for Neutrophil-mediated Endothelial Damage in Chronic Obstructive Pulmonary Disease
Lodge, Katharine M, Vassallo, Arlette, Liu, Bin, Long, Merete, Tong, Zhen, Newby, Paul R, Agha-Jaffar, Danya, Paschalaki, Koralia, Green, Clara E, Belchamber, Kylie B R, Ridger, Victoria C, Stockley, Robert A, Sapey, Elizabeth, Summers, Charlotte, Cowburn, Andrew S, Chilvers, Edwin R, Li, Wei, Condliffe, Alison M
Published in American journal of respiratory and critical care medicine (15.04.2022)
Published in American journal of respiratory and critical care medicine (15.04.2022)
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Journal Article
Advances in neutrophil biology: clinical implications
Cowburn, Andrew S, Condliffe, Alison M, Farahi, Neda, Summers, Charlotte, Chilvers, Edwin R
Published in Chest (01.09.2008)
Published in Chest (01.09.2008)
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