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An interspecies analysis reveals a key role for unmethylated CpG dinucleotides in vertebrate Polycomb complex recruitment
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Intrinsic factors and the embryonic environment influence the formation of extragonadal teratomas during gestation
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Impaired B and T Cell Antigen Receptor Signaling in p110δ PI 3-Kinase Mutant Mice
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Published in Science (American Association for the Advancement of Science) (09.08.2002)
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Chromosome looping at the human α-globin locus is mediated via the major upstream regulatory element (HS −40)
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Association between active genes occurs at nuclear speckles and is modulated by chromatin environment
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Polycomb eviction as a new distant enhancer function
Vernimmen, Douglas, Lynch, Magnus D, De Gobbi, Marco, Garrick, David, Sharpe, Jacqueline A, Sloane-Stanley, Jacqueline A, Smith, Andrew J H, Higgs, Douglas R
Published in Genes & development (01.08.2011)
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Expression of Butyrophilin (Btn1a1) in Lactating Mammary Gland Is Essential for the Regulated Secretion of Milk-Lipid Droplets
Ogg, Sherry L., Weldon, Anne K., Dobbie, Lorraine, Andrew J. H. Smith, Mather, Ian H., Baldwin, Ransom L.
Published in Proceedings of the National Academy of Sciences - PNAS (06.07.2004)
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Hes1 Desynchronizes Differentiation of Pluripotent Cells by Modulating STAT3 Activity
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Experimental acute pancreatitis in PAP/HIP knock-out mice
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Altered nociception, analgesia and aggression in mice lacking the receptor for substance P
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Published in Nature (London) (26.03.1998)
Published in Nature (London) (26.03.1998)
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DNA methylation of intragenic CpG islands depends on their transcriptional activity during differentiation and disease
Jeziorska, Danuta M., Murray, Robert J. S., De Gobbi, Marco, Gaentzsch, Ricarda, Garrick, David, Ayyub, Helena, Chen, Taiping, Li, En, Telenius, Jelena, Lynch, Magnus, Graham, Bryony, Smith, Andrew J. H., Lund, Jonathan N., Hughes, Jim R., Higgs, Douglas R., Tufarelli, Cristina
Published in Proceedings of the National Academy of Sciences - PNAS (05.09.2017)
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Genetic dissection of the α-globin super-enhancer in vivo
Hay, Deborah, Hughes, Jim R, Babbs, Christian, Davies, James O J, Graham, Bryony J, Hanssen, Lars, Kassouf, Mira T, Marieke Oudelaar, A Marieke, Sharpe, Jacqueline A, Suciu, Maria C, Telenius, Jelena, Williams, Ruth, Rode, Christina, Li, Pik-Shan, Pennacchio, Len A, Sloane-Stanley, Jacqueline A, Ayyub, Helena, Butler, Sue, Sauka-Spengler, Tatjana, Gibbons, Richard J, Smith, Andrew J H, Wood, William G, Higgs, Douglas R
Published in Nature genetics (01.08.2016)
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Reg2 inactivation increases sensitivity to Fas hepatotoxicity and delays liver regeneration post‐hepatectomy in mice
Lieu, Hanh‐Tu, Simon, Marie‐Thérèse, Nguyen‐Khoa, Thao, Kebede, Messeret, Cortes, Alexandre, Tebar, Luis, Smith, Andrew J. H., Bayne, Rosemary, Hunt, Stephen P., Bréchot, Christian, Christa, Laurence
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Two Genetically Separable Steps in the Differentiation of Thymic Epithelium
Nehls, Michael, Kyewski, Bruno, Messerle, Martin, Waldschütz, Ralph, Schüddekopf, Kerstin, Andrew J. H. Smith, Boehm, Thomas
Published in Science (American Association for the Advancement of Science) (10.05.1996)
Published in Science (American Association for the Advancement of Science) (10.05.1996)
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A Human IPS Model Implicates Embryonic B-Myeloid Fate Restriction as Developmental Susceptibility to B Acute Lymphoblastic Leukemia-Associated ETV6-RUNX1
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Published in Developmental cell (05.02.2018)
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