new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs
Prota, Andrea E., Bargsten, Katja, Diaz, J. Fernando, Marsh, May, Cuevas, Carmen, Liniger, Marc, Neuhaus, Christian, Andreu, Jose M., Altmann, Karl-Heinz, Steinmetz, Michel O.
Published in Proceedings of the National Academy of Sciences - PNAS (23.09.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (23.09.2014)
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Stathmin and Interfacial Microtubule Inhibitors Recognize a Naturally Curved Conformation of Tubulin Dimers
Barbier, Pascale, Dorléans, Audrey, Devred, Francois, Sanz, Laura, Allegro, Diane, Alfonso, Carlos, Knossow, Marcel, Peyrot, Vincent, Andreu, Jose M.
Published in The Journal of biological chemistry (08.10.2010)
Published in The Journal of biological chemistry (08.10.2010)
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Journal Article
Tocilizumab in COVID-19: Factors Associated With Mortality Before and After Treatment
Sarabia De Ardanaz, Luis, Andreu-Ubero, Jose M., Navidad-Fuentes, Miriam, Ferrer-González, Miguel Ángel, Ruíz del Valle, Victor, Salcedo-Bellido, Inmaculada, Barrios-Rodríguez, Rocío, Cáliz-Cáliz, Rafael, Requena, Pilar
Published in Frontiers in pharmacology (01.07.2021)
Published in Frontiers in pharmacology (01.07.2021)
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Journal Article
Biosafety and biosecurity in Synthetic Biology: A review
Gómez-Tatay, Lucía, Hernández-Andreu, José M.
Published in Critical reviews in environmental science and technology (02.09.2019)
Published in Critical reviews in environmental science and technology (02.09.2019)
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Journal Article
Conserved GTPase mechanism in bacterial FtsZ and archaeal tubulin filaments
Andreu, José M., Ruiz, Federico M., Fernández‐Tornero, Carlos
Published in The FEBS journal (01.07.2023)
Published in The FEBS journal (01.07.2023)
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Journal Article
Bacterial cell division proteins as antibiotic targets
den Blaauwen, Tanneke, Andreu, José M., Monasterio, Octavio
Published in Bioorganic chemistry (01.08.2014)
Published in Bioorganic chemistry (01.08.2014)
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Journal Article
Beta-Trace Protein and Cystatin C as Predictors of Major Bleeding in Non-ST-Segment Elevation Acute Coronary Syndrome
López-Cuenca, Ángel, Manzano-Fernández, Sergio, Marín, Francisco, Parra-Pallares, Soledad, Navarro-Peñalver, Marina, Montalban-Larrea, Salvador, Andreu-Cayuelas, Jose M., Romero-Aniorte, Ana I., Avilés-Plaza, Francisco, Valdés-Chavarri, Mariano, Januzzi, James L., Jr
Published in Circulation Journal (2013)
Published in Circulation Journal (2013)
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Journal Article
The Antibacterial Cell Division Inhibitor PC190723 Is an FtsZ Polymer-stabilizing Agent That Induces Filament Assembly and Condensation
Andreu, José M., Schaffner-Barbero, Claudia, Huecas, Sonia, Alonso, Dulce, Lopez-Rodriguez, María L., Ruiz-Avila, Laura B., Núñez-Ramírez, Rafael, Llorca, Oscar, Martín-Galiano, Antonio J.
Published in The Journal of biological chemistry (07.05.2010)
Published in The Journal of biological chemistry (07.05.2010)
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Journal Article
Targeting the FtsZ Allosteric Binding Site with a Novel Fluorescence Polarization Screen, Cytological and Structural Approaches for Antibacterial Discovery
Huecas, Sonia, Araújo-Bazán, Lidia, Ruiz, Federico M, Ruiz-Ávila, Laura B, Martínez, R. Fernando, Escobar-Peña, Andrea, Artola, Marta, Vázquez-Villa, Henar, Martín-Fontecha, Mar, Fernández-Tornero, Carlos, López-Rodríguez, María L, Andreu, José M
Published in Journal of medicinal chemistry (13.05.2021)
Published in Journal of medicinal chemistry (13.05.2021)
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Journal Article
Targeting the Assembly of Bacterial Cell Division Protein FtsZ with Small Molecules
Schaffner-Barbero, Claudia, Martín-Fontecha, Mar, Chacón, Pablo, Andreu, José M
Published in ACS chemical biology (17.02.2012)
Published in ACS chemical biology (17.02.2012)
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Journal Article
Self-Organization of FtsZ Polymers in Solution Reveals Spacer Role of the Disordered C-Terminal Tail
Huecas, Sonia, Ramírez-Aportela, Erney, Vergoñós, Albert, Núñez-Ramírez, Rafael, Llorca, Oscar, Díaz, J. Fernando, Juan-Rodríguez, David, Oliva, María A., Castellen, Patricia, Andreu, José M.
Published in Biophysical journal (17.10.2017)
Published in Biophysical journal (17.10.2017)
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Journal Article
Synthesis and Antimitotic and Tubulin Interaction Profiles of Novel Pinacol Derivatives of Podophyllotoxins
Abad, Andrés, López-Pérez, José L, del Olmo, Esther, García-Fernández, Luis F, Francesch, Andrés, Trigili, Chiara, Barasoain, Isabel, Andreu, José M, Díaz, J. Fernando, San Feliciano, Arturo
Published in Journal of medicinal chemistry (09.08.2012)
Published in Journal of medicinal chemistry (09.08.2012)
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Journal Article
Tubulin homolog TubZ in a phage-encoded partition system
Oliva, María A, Martin-Galiano, Antonio J, Sakaguchi, Yoshihiko, Andreu, José M
Published in Proceedings of the National Academy of Sciences - PNAS (15.05.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (15.05.2012)
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Journal Article
The structural assembly switch of cell division protein FtsZ probed with fluorescent allosteric inhibitors
Artola, Marta, Ruiz-Avila, Laura B., Ramirez-Aportela, Erney, Fernando Martinez, R., Araujo-Bazan, Lidia, Vazquez-Villa, Henar, Martin-Fontecha, Mar, Oliva, Maria A., Javier Martin-Galiano, A., Chacon, Pablo, Lopez-Rodriguez, Maria L., Andreu, Jose M., Huecas, Sonia
Published in Chemical science (Cambridge) (01.02.2017)
Published in Chemical science (Cambridge) (01.02.2017)
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Journal Article
PM060184, a new tubulin binding agent with potent antitumor activity including P-glycoprotein over-expressing tumors
Martínez-Díez, Marta, Guillén-Navarro, María José, Pera, Benet, Bouchet, Benjamin Pierre, Martínez-Leal, Juan Fernando, Barasoain, Isabel, Cuevas, Carmen, Andreu, Jose M., García-Fernández, Luis Francisco, Díaz, J. Fernando, Avilés, Pablo, Galmarini, Carlos M.
Published in Biochemical pharmacology (01.04.2014)
Published in Biochemical pharmacology (01.04.2014)
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