A transcriptional switch governs fibroblast activation in heart disease
Alexanian, Michael, Przytycki, Pawel F., Micheletti, Rudi, Padmanabhan, Arun, Ye, Lin, Travers, Joshua G., Gonzalez-Teran, Barbara, Silva, Ana Catarina, Duan, Qiming, Ranade, Sanjeev S., Felix, Franco, Linares-Saldana, Ricardo, Li, Li, Lee, Clara Youngna, Sadagopan, Nandhini, Pelonero, Angelo, Huang, Yu, Andreoletti, Gaia, Jain, Rajan, McKinsey, Timothy A., Rosenfeld, Michael G., Gifford, Casey A., Pollard, Katherine S., Haldar, Saptarsi M., Srivastava, Deepak
Published in Nature (London) (15.07.2021)
Published in Nature (London) (15.07.2021)
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Journal Article
Transcriptomics-based drug repositioning pipeline identifies therapeutic candidates for COVID-19
Le, Brian L., Andreoletti, Gaia, Oskotsky, Tomiko, Vallejo-Gracia, Albert, Rosales, Romel, Yu, Katharine, Kosti, Idit, Leon, Kristoffer E., Bunis, Daniel G., Li, Christine, Kumar, G. Renuka, White, Kris M., García-Sastre, Adolfo, Ott, Melanie, Sirota, Marina
Published in Scientific reports (10.06.2021)
Published in Scientific reports (10.06.2021)
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Journal Article
Loss of Mtm1 causes cholestatic liver disease in a model of X-linked myotubular myopathy
Karolczak, Sophie, Deshwar, Ashish R, Aristegui, Evangelina, Kamath, Binita M, Lawlor, Michael W, Andreoletti, Gaia, Volpatti, Jonathan R, Ellis, Jillian L, Yin, Chunyue, Dowling, James J
Published in The Journal of clinical investigation (15.09.2023)
Published in The Journal of clinical investigation (15.09.2023)
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Journal Article
Transcriptomic analysis of immune cells in a multi-ethnic cohort of systemic lupus erythematosus patients identifies ethnicity- and disease-specific expression signatures
Andreoletti, Gaia, Lanata, Cristina M., Trupin, Laura, Paranjpe, Ishan, Jain, Tia S., Nititham, Joanne, Taylor, Kimberly E., Combes, Alexis J., Maliskova, Lenka, Ye, Chun Jimmie, Katz, Patricia, Dall’Era, Maria, Yazdany, Jinoos, Criswell, Lindsey A., Sirota, Marina
Published in Communications biology (21.04.2021)
Published in Communications biology (21.04.2021)
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Journal Article
Crowdsourcing assessment of maternal blood multi-omics for predicting gestational age and preterm birth
Tarca, Adi L., Pataki, Bálint Ármin, Romero, Roberto, Sirota, Marina, Guan, Yuanfang, Kutum, Rintu, Gomez-Lopez, Nardhy, Done, Bogdan, Bhatti, Gaurav, Yu, Thomas, Andreoletti, Gaia, Chaiworapongsa, Tinnakorn, Hassan, Sonia S., Hsu, Chaur-Dong, Aghaeepour, Nima, Stolovitzky, Gustavo, Csabai, Istvan, Costello, James C.
Published in Cell reports. Medicine (15.06.2021)
Published in Cell reports. Medicine (15.06.2021)
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Journal Article
Functional screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair
Perez-Bermejo, Juan A., Efagene, Oghene, Matern, William M., Holden, Jeffrey K., Kabir, Shaheen, Chew, Glen M., Andreoletti, Gaia, Catton, Eniola, Ennis, Craig L., Garcia, Angelica, Gerstenberg, Trevor L., Hill, Kaisle A., Jain, Aayami, Krassovsky, Kristina, Lalisan, Cassandra D., Lord, Daniel, Quejarro, B. Joy, Sales-Lee, Jade, Shah, Meet, Silva, Brian J., Skowronski, Jason, Strukov, Yuri G., Thomas, Joshua, Veraz, Michael, Vijay, Twaritha, Wallace, Kirby A., Yuan, Yue, Grogan, Jane L., Wienert, Beeke, Lahiri, Premanjali, Treusch, Sebastian, Dever, Daniel P., Soros, Vanessa B., Partridge, James R., Seim, Kristen L.
Published in Nature communications (23.03.2024)
Published in Nature communications (23.03.2024)
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Journal Article
Exome Analysis of Rare and Common Variants within the NOD Signaling Pathway
Andreoletti, Gaia, Shakhnovich, Valentina, Christenson, Kathy, Coelho, Tracy, Haggarty, Rachel, Afzal, Nadeem A, Batra, Akshay, Petersen, Britt-Sabina, Mort, Matthew, Beattie, R. Mark, Ennis, Sarah
Published in Scientific reports (19.04.2017)
Published in Scientific reports (19.04.2017)
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Journal Article
Unexpected Findings in a Child with Atypical Hemolytic Uremic Syndrome: An Example of How Genomics Is Changing the Clinical Diagnostic Paradigm
Seaby, Eleanor G, Gilbert, Rodney D, Andreoletti, Gaia, Pengelly, Reuben J, Mercer, Catherine, Hunt, David, Ennis, Sarah
Published in Frontiers in pediatrics (22.05.2017)
Published in Frontiers in pediatrics (22.05.2017)
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Journal Article
Progressive myoclonic epilepsy with Fanconi syndrome
Seaby, Eleanor G, Gilbert, Rodney D, Pengelly, Reuben J, Andreoletti, Gaia, Clarke, Antonia, Ennis, Sarah
Published in JRSM open (01.06.2016)
Published in JRSM open (01.06.2016)
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Journal Article
Reports from the fifth edition of CAGI: The Critical Assessment of Genome Interpretation
Andreoletti, Gaia, Pal, Lipika R., Moult, John, Brenner, Steven E.
Published in Human mutation (01.09.2019)
Published in Human mutation (01.09.2019)
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Journal Article
Back Cover, Volume 40, Issue 9
Andreoletti, Gaia, Pal, Lipika R., Moult, John, Brenner, Steven E.
Published in Human mutation (01.09.2019)
Published in Human mutation (01.09.2019)
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Journal Article
Abstract LB-250: The Critical Assessment of Genome Interpretation: A community experiment that informs use of methods for germline cancer variant impact prediction
Bakolitsa, Constantina, Andreoletti, Gaia, Hoskins, Roger, Radivojac, Predrag, Moult, John, Brenner, Steven
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Reports from CAGI: The Critical Assessment of Genome Interpretation
Hoskins, Roger A, Repo, Susanna, Barsky, Daniel, Andreoletti, Gaia, Moult, John, Brenner, Steven E.
Published in Human mutation (01.09.2017)
Published in Human mutation (01.09.2017)
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Journal Article
VIPdb, a genetic Variant Impact Predictor Database
Hu, Zhiqiang, Yu, Changhua, Furutsuki, Mabel, Andreoletti, Gaia, Ly, Melissa, Hoskins, Roger, Adhikari, Aashish N., Brenner, Steven E.
Published in Human mutation (01.09.2019)
Published in Human mutation (01.09.2019)
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Journal Article
High-throughput transcriptome analyses from ASPIRO, a phase 1/2/3 study of gene replacement therapy for X-linked myotubular myopathy
Andreoletti, Gaia, Romano, Oriana, Chou, Hsin-Jung, Sefid-Dashti, Mahjoubeh J., Grilli, Andrea, Chen, Clarice, Lakshman, Neema, Purushothaman, Pravin, Varfaj, Fatbardha, Mavilio, Fulvio, Bicciato, Silvio, Urbinati, Fabrizia
Published in American journal of human genetics (05.10.2023)
Published in American journal of human genetics (05.10.2023)
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Journal Article
BRD4 (Bromodomain-Containing Protein 4) Interacts with GATA4 (GATA Binding Protein 4) to Govern Mitochondrial Homeostasis in Adult Cardiomyocytes
Padmanabhan, Arun, Alexanian, Michael, Linares-Saldana, Ricardo, González-Terán, Bárbara, Andreoletti, Gaia, Huang, Yu, Connolly, Andrew J., Kim, Wonho, Hsu, Austin, Duan, Qiming, Winchester, Sarah A.B., Felix, Franco, Perez-Bermejo, Juan A., Wang, Qiaohong, Li, Li, Shah, Parisha P., Haldar, Saptarsi M., Jain, Rajan, Srivastava, Deepak
Published in Circulation (New York, N.Y.) (15.12.2020)
Published in Circulation (New York, N.Y.) (15.12.2020)
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Journal Article
Development of a β-Globin Gene Replacement Strategy As a β-Thalassemia Therapy
Wallace, Kirby, Wienert, Beeke, Bandoro, Christopher, Partridge, James, Ennis, Craig L., Lalisan, Casey D., Krassovsky, Kristina, Andreoletti, Gaia, Sharma, Rajiv, Churi, Aishwarya, Matern, William M., Treusch, Sebastian, Grogan, Jane, Dever, Daniel P.
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
Identification of Variants in Genes Associated with Single-gene Inflammatory Bowel Disease by Whole-exome Sequencing
Ashton, James J, Andreoletti, Gaia, Coelho, Tracy, Haggarty, Rachel, Batra, Akshay, Afzal, Nadeem A, Beattie, R Mark, Ennis, Sarah
Published in Inflammatory bowel diseases (01.10.2016)
Published in Inflammatory bowel diseases (01.10.2016)
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Journal Article
Abstract 3295: CAGI: The Critical Assessment of Genome Interpretation, a community experiment to evaluate phenotype prediction: implications for predicting impact of variants in cancer
Andreoletti, Gaia, Hoskins, Roger A., Repo, Susanna, Barsky, Daniel, Brenner, Steven E., Mult, John, participants, Cagi
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Genes implicated in thiopurine-induced toxicity: Comparing TPMT enzyme activity with clinical phenotype and exome data in a paediatric IBD cohort
Coelho, Tracy, Andreoletti, Gaia, Ashton, James J., Batra, Akshay, Afzal, Nadeem Ahmad, Gao, Yifang, Williams, Anthony P., Beattie, Robert M., Ennis, Sarah
Published in Scientific reports (05.10.2016)
Published in Scientific reports (05.10.2016)
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Journal Article