MYC and MCL1 Cooperatively Promote Chemotherapy-Resistant Breast Cancer Stem Cells via Regulation of Mitochondrial Oxidative Phosphorylation
Lee, Kyung-min, Giltnane, Jennifer M., Balko, Justin M., Schwarz, Luis J., Guerrero-Zotano, Angel L., Hutchinson, Katherine E., Nixon, Mellissa J., Estrada, Mónica V., Sánchez, Violeta, Sanders, Melinda E., Lee, Taekyu, Gómez, Henry, Lluch, Ana, Pérez-Fidalgo, J. Alejandro, Wolf, Melissa Magdalene, Andrejeva, Gabriela, Rathmell, Jeffrey C., Fesik, Stephen W., Arteaga, Carlos L.
Published in Cell metabolism (03.10.2017)
Published in Cell metabolism (03.10.2017)
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Journal Article
Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism
Johnson, Marc O., Wolf, Melissa M., Madden, Matthew Z., Andrejeva, Gabriela, Sugiura, Ayaka, Contreras, Diana C., Maseda, Damian, Liberti, Maria V., Paz, Katelyn, Kishton, Rigel J., Johnson, Matthew E., de Cubas, Aguirre A., Wu, Pingsheng, Li, Gongbo, Zhang, Yongliang, Newcomb, Dawn C., Wells, Andrew D., Restifo, Nicholas P., Rathmell, W. Kimryn, Locasale, Jason W., Davila, Marco L., Blazar, Bruce R., Rathmell, Jeffrey C.
Published in Cell (13.12.2018)
Published in Cell (13.12.2018)
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Journal Article
De novo phosphatidylcholine synthesis is required for autophagosome membrane formation and maintenance during autophagy
Andrejeva, Gabriela, Gowan, Sharon, Lin, Gigin, Wong Te Fong, Anne-Christine LF, Shamsaei, Elham, Parkes, Harry G., Mui, James, Raynaud, Florence I., Asad, Yasmin, Vizcay-Barrena, Gema, Nikitorowicz-Buniak, Joanna, Valenti, Melanie, Howell, Louise, Fleck, Roland A., Martin, Lesley-Ann, Kirkin, Vladimir, Leach, Martin O., Chung, Yuen-Li
Published in Autophagy (02.06.2020)
Published in Autophagy (02.06.2020)
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Journal Article
260 CD47 antibody, AO-176 demonstrates potent anti-tumor activity in pre-clinical solid tumor xenografts as a single agent and in combination with multiple classes of therapeutics
Andrejeva, Gabriela, Capoccia, Benjamin, Delston, Rachel, Donio, Michael, Hiebsch, Ronald, Puro, Robyn, Wilson, Casey, Kashyap, Arun, Pereira, Daniel
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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Journal Article
Mutant KRAS Exosomes Alter the Metabolic State of Recipient Colonic Epithelial Cells
Zhang, Qin, Jeppesen, Dennis K, Higginbotham, James N, Demory Beckler, Michelle, Poulin, Emily J, Walsh, Alex J, Skala, Melissa C, McKinley, Eliot T, Manning, H. Charles, Hight, Matthew R, Schulte, Michael L, Watt, Kimberly R, Ayers, G. Daniel, Wolf, Melissa M, Andrejeva, Gabriela, Rathmell, Jeffrey C, Franklin, Jeffrey L, Coffey, Robert J
Published in Cellular and molecular gastroenterology and hepatology (01.01.2018)
Published in Cellular and molecular gastroenterology and hepatology (01.01.2018)
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Journal Article
Reduced Warburg effect in cancer cells undergoing autophagy: steady- state 1H-MRS and real-time hyperpolarized 13C-MRS studies
Lin, Gigin, Andrejeva, Gabriela, Wong Te Fong, Anne-Christine, Hill, Deborah K, Orton, Matthew R, Parkes, Harry G, Koh, Dow-Mu, Robinson, Simon P, Leach, Martin O, Eykyn, Thomas R, Chung, Yuen-Li
Published in PloS one (2014)
Published in PloS one (2014)
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Journal Article
MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function
Sugiura, Ayaka, Andrejeva, Gabriela, Voss, Kelsey, Heintzman, Darren R., Xu, Xincheng, Madden, Matthew Z., Ye, Xiang, Beier, Katherine L., Chowdhury, Nowrin U., Wolf, Melissa M., Young, Arissa C., Greenwood, Dalton L., Sewell, Allison E., Shahi, Shailesh K., Freedman, Samantha N., Cameron, Alanna M., Foerch, Patrik, Bourne, Tim, Garcia-Canaveras, Juan C., Karijolich, John, Newcomb, Dawn C., Mangalam, Ashutosh K., Rabinowitz, Joshua D., Rathmell, Jeffrey C.
Published in Immunity (Cambridge, Mass.) (11.01.2022)
Published in Immunity (Cambridge, Mass.) (11.01.2022)
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Journal Article
Novel SIRPα Antibodies That Induce Single-Agent Phagocytosis of Tumor Cells while Preserving T Cells
Andrejeva, Gabriela, Capoccia, Benjamin J, Hiebsch, Ronald R, Donio, Michael J, Darwech, Isra M, Puro, Robyn J, Pereira, Daniel S
Published in The Journal of immunology (1950) (15.02.2021)
Published in The Journal of immunology (1950) (15.02.2021)
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Journal Article
AO-176, a Differentiated Clinical-Stage Anti-CD47 Antibody, Demonstrates Potent Anti-Tumor Activity across Multiple Preclinical Models of B Cell Neoplasms
Wilson, William Casey, Richards, John O, Andrejeva, Gabriela, Capoccia, Benjamin J, Puro, Robyn J, Donio, Mike J, Hiebsch, Ronald R, Kashyap, Arun K, Pereira, Daniel S
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Journal Article
Targeting PIM Kinase with PD1 Inhibition Improves Immunotherapeutic Antitumor T-cell Response
Chatterjee, Shilpak, Chakraborty, Paramita, Daenthanasanmak, Anusara, Iamsawat, Supinya, Andrejeva, Gabriela, Luevano, Libia A, Wolf, Melissa, Baliga, Uday, Krieg, Carsten, Beeson, Craig C, Mehrotra, Meenal, Hill, Elizabeth G, Rathmell, Jeffery C, Yu, Xue-Zhong, Kraft, Andrew S, Mehrotra, Shikhar
Published in Clinical cancer research (01.02.2019)
Published in Clinical cancer research (01.02.2019)
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Journal Article
Mitochondrial dysregulation and glycolytic insufficiency functionally impair CD8 T cells infiltrating human renal cell carcinoma
Siska, Peter J, Beckermann, Kathryn E, Mason, Frank M, Andrejeva, Gabriela, Greenplate, Allison R, Sendor, Adam B, Chiang, Yun-Chen J, Corona, Armando L, Gemta, Lelisa F, Vincent, Benjamin G, Wang, Richard C, Kim, Bumki, Hong, Jiyong, Chen, Chiu-Lan, Bullock, Timothy N, Irish, Jonathan M, Rathmell, W Kimryn, Rathmell, Jeffrey C
Published in JCI insight (15.06.2017)
Published in JCI insight (15.06.2017)
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Journal Article
Pre-Clinical Combination of AO-176, a Highly Differentiated Clinical Stage CD47 Antibody, with Either Azacitidine or Venetoclax Significantly Enhances DAMP Induction and Phagocytosis of Acute Myeloid Leukemia
Donio, Mike J, Wilson, W. Casey, Darwech, Isra, Andrejeva, Gabriela, Capoccia, Benjamin J, Puro, Robyn J, Kashyap, Arun K, Pereira, Daniel S
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
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Journal Article
AO-176, a Highly Differentiated Clinical Stage Anti-CD47 Antibody, Exerts Potent Anti-Tumor Activity in Preclinical Models of Multiple Myeloma As a Single Agent and in Combination with Approved Therapeutics
Wilson, William Casey, Richards, John, Puro, Robyn J, Andrejeva, Gabriela, Capoccia, Ben J, Donio, Mike J, Hiebsch, Ronald R, Chakraborty, Prabir, Sung, Victoria, Pereira, Daniel S
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
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Journal Article
Divergent roles of retinoic acid signaling in T regulatory cell function
Thangavelu, Govindarajan, Andrejeva, Gabriela, Loschi, Michael, Aguilar, Ethan G, Lee, Yu-Chi, Furlan, Scott N, McDonald-Hyman, Cameron, Zaiken, Michael C, Feser, Colby J, Panoskaltsis-Mortari, Angela, Kean, Leslie S, Rathmell, Jeffrey C, Chi, Hongbo, Noelle, Randolph J, Blazar, Bruce R
Published in The Journal of immunology (1950) (01.05.2020)
Published in The Journal of immunology (1950) (01.05.2020)
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Journal Article
Basis of the Intrinsic Flexibility of the Cε3 Domain of IgE
Borthakur, Susmita, Andrejeva, Gabriela, McDonnell, James M
Published in Biochemistry (Easton) (31.05.2011)
Published in Biochemistry (Easton) (31.05.2011)
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Journal Article
Linking Microenvironmental Signals to Metabolic Switches and Drug Responses in Chronic Lymphocytic Leukemia
Chen, Zhenghao, Cretenet, Gaspard, ter Burg, Hanneke, Andrejeva, Gabriela, Rathmell, Jeffrey C, Forconi, Francesco, van der Windt, Gerritje J.W., Kater, Arnon P., Eldering, Eric
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Journal Article
Targeting PIM Kinase with PD1 inhibition Improves Immunotherapeutic Anti-Tumor T Cell Response
Chatterjee, Shilpak, Chakraborty, Paramita, Daenthanasanmak, Anusara, Iamsawat, Supinya, Andrejeva, Gabriela, Luevano, Libia A, Wolf, Melissa, Baliga, Uday, Krieg, Carsten, Beeson, Craig C., Mehrotra, Meenal, Hill, Elizabeth G., Rathmell, Jeffery C., Yu, Xue-Zhong, Kraft, Andrew S., Mehrotra, Shikhar
Published in Clinical cancer research (16.10.2018)
Published in Clinical cancer research (16.10.2018)
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Journal Article
Retinoic acid signaling acts as a rheostat to balance Treg function
Thangavelu, Govindarajan, Andrejeva, Gabriela, Bolivar-Wagers, Sara, Jin, Sujeong, Zaiken, Michael C., Loschi, Michael, Aguilar, Ethan G., Furlan, Scott N., Brown, Chrysothemis C., Lee, Yu-Chi, Hyman, Cameron McDonald, Feser, Colby J., Panoskaltsis-Mortari, Angela, Hippen, Keli L., MacDonald, Kelli P., Murphy, William J., Maillard, Ivan, Hill, Geoffrey R., Munn, David H., Zeiser, Robert, Kean, Leslie S., Rathmell, Jeffrey C., Chi, Hongbo, Noelle, Randolph J., Blazar, Bruce R.
Published in Cellular & molecular immunology (01.07.2022)
Published in Cellular & molecular immunology (01.07.2022)
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Journal Article
Metabolomics analysis reveals differential T cell serine metabolism as a target in autoimmunity
Andrejeva, Gabriela, Wolf, Melissa M., Johnson, Marc O., Rutledge, Alexandra C., Codreanu, Gabriela S., Sherrod, Stacy D., Gutierrez, Danielle, Rose, Kristie L., Norris, Jeremy L., Schey, Kevin L., McLean, John A., Rathmell, Jeffrey C.
Published in The Journal of immunology (1950) (01.05.2018)
Published in The Journal of immunology (1950) (01.05.2018)
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Journal Article