CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities
Han, Kyuho, Pierce, Sarah E., Li, Amy, Spees, Kaitlyn, Anderson, Gray R., Seoane, Jose A., Lo, Yuan-Hung, Dubreuil, Michael, Olivas, Micah, Kamber, Roarke A., Wainberg, Michael, Kostyrko, Kaja, Kelly, Marcus R., Yousefi, Maryam, Simpkins, Scott W., Yao, David, Lee, Keonil, Kuo, Calvin J., Jackson, Peter K., Sweet-Cordero, Alejandro, Kundaje, Anshul, Gentles, Andrew J., Curtis, Christina, Winslow, Monte M., Bassik, Michael C.
Published in Nature (London) (01.04.2020)
Published in Nature (London) (01.04.2020)
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Systematic mapping of BCL-2 gene dependencies in cancer reveals molecular determinants of BH3 mimetic sensitivity
Soderquist, Ryan S., Crawford, Lorin, Liu, Esther, Lu, Min, Agarwal, Anika, Anderson, Gray R., Lin, Kevin H., Winter, Peter S., Cakir, Merve, Wood, Kris C.
Published in Nature communications (29.08.2018)
Published in Nature communications (29.08.2018)
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Dysregulation of mitochondrial dynamics proteins are a targetable feature of human tumors
Anderson, Gray R., Wardell, Suzanne E., Cakir, Merve, Yip, Catherine, Ahn, Yeong-ran, Ali, Moiez, Yllanes, Alexander P., Chao, Christina A., McDonnell, Donald P., Wood, Kris C.
Published in Nature communications (26.04.2018)
Published in Nature communications (26.04.2018)
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Codon bias imposes a targetable limitation on KRAS-driven therapeutic resistance
Ali, Moiez, Kaltenbrun, Erin, Anderson, Gray R., Stephens, Sarah Jo, Arena, Sabrina, Bardelli, Alberto, Counter, Christopher M., Wood, Kris C.
Published in Nature communications (08.06.2017)
Published in Nature communications (08.06.2017)
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Targeting MCL-1/BCL-XL Forestalls the Acquisition of Resistance to ABT-199 in Acute Myeloid Leukemia
Lin, Kevin H., Winter, Peter S., Xie, Abigail, Roth, Cullen, Martz, Colin A., Stein, Elizabeth M., Anderson, Gray R., Tingley, Jennifer P., Wood, Kris C.
Published in Scientific reports (10.06.2016)
Published in Scientific reports (10.06.2016)
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Using antagonistic pleiotropy to design a chemotherapy-induced evolutionary trap to target drug resistance in cancer
Lin, Kevin H., Rutter, Justine C., Xie, Abigail, Pardieu, Bryann, Winn, Emily T., Bello, Reinaldo Dal, Forget, Antoine, Itzykson, Raphael, Ahn, Yeong-Ran, Dai, Ziwei, Sobhan, Raiyan T., Anderson, Gray R., Singleton, Katherine R., Decker, Amy E., Winter, Peter S., Locasale, Jason W., Crawford, Lorin, Puissant, Alexandre, Wood, Kris C.
Published in Nature genetics (01.04.2020)
Published in Nature genetics (01.04.2020)
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Systematic identification of signaling pathways with potential to confer anticancer drug resistance
Martz, Colin A, Ottina, Kathleen A, Singleton, Katherine R, Jasper, Jeff S, Wardell, Suzanne E, Peraza-Penton, Ashley, Anderson, Grace R, Winter, Peter S, Wang, Tim, Alley, Holly M, Kwong, Lawrence N, Cooper, Zachary A, Tetzlaff, Michael, Chen, Pei-Ling, Rathmell, Jeffrey C, Flaherty, Keith T, Wargo, Jennifer A, McDonnell, Donald P, Sabatini, David M, Wood, Kris C
Published in Science signaling (23.12.2014)
Published in Science signaling (23.12.2014)
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PIK3CA mutations enable targeting of a breast tumor dependency through mTOR-mediated MCL-1 translation
Anderson, Gray R, Wardell, Suzanne E, Cakir, Merve, Crawford, Lorin, Leeds, Jim C, Nussbaum, Daniel P, Shankar, Pallavi S, Soderquist, Ryan S, Stein, Elizabeth M, Tingley, Jennifer P, Winter, Peter S, Zieser-Misenheimer, Elizabeth K, Alley, Holly M, Yllanes, Alexander, Haney, Victoria, Blackwell, Kimberly L, McCall, Shannon J, McDonnell, Donald P, Wood, Kris C
Published in Science translational medicine (14.12.2016)
Published in Science translational medicine (14.12.2016)
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Cellphone enabled point-of-care assessment of breast tumor cytology and molecular HER2 expression from fine-needle aspirates
Joh, Daniel Y., Heggestad, Jacob T., Zhang, Shengwei, Anderson, Gray R., Bhattacharyya, Jayanta, Wardell, Suzanne E., Wall, Simone A., Cheng, Amy B., Albarghouthi, Faris, Liu, Jason, Oshima, Sachi, Hucknall, Angus M., Hyslop, Terry, Hall, Allison H. S., Wood, Kris C., Shelley Hwang, E., Strickland, Kyle C., Wei, Qingshan, Chilkoti, Ashutosh
Published in NPJ breast cancer (02.07.2021)
Published in NPJ breast cancer (02.07.2021)
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Genomically informed small-molecule drugs overcome resistance to a sustained-release formulation of an engineered death receptor agonist in patient-derived tumor models
Manzari, Mandana T, Anderson, Gray R, Lin, Kevin H, Soderquist, Ryan S, Çakir, Merve, Zhang, Mitchell, Moore, Chandler E, Skelton, Rachel N, Fèvre, Maréva, Li, Xinghai, Bellucci, Joseph J, Wardell, Suzanne E, Costa, Simone A, Wood, Kris C, Chilkoti, Ashutosh
Published in Science advances (01.09.2019)
Published in Science advances (01.09.2019)
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Author Correction: Cellphone enabled point-of-care assessment of breast tumor cytology and molecular HER2 expression from fine-needle aspirates
Joh, Daniel Y., Heggestad, Jacob T., Zhang, Shengwei, Anderson, Gray R., Bhattacharyya, Jayanta, Wardell, Suzanne E., Wall, Simone A., Cheng, Amy B., Albarghouthi, Faris, Liu, Jason, Oshima, Sachi, Hucknall, Angus M., Hyslop, Terry, Hall, Allison H. S., Wood, Kris C., Shelley Hwang, E., Strickland, Kyle C., Wei, Qingshan, Chilkoti, Ashutosh
Published in NPJ breast cancer (17.09.2021)
Published in NPJ breast cancer (17.09.2021)
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MCB-613 exploits a collateral sensitivity in drug-resistant EGFR-mutant non-small cell lung cancer through covalent inhibition of KEAP1
Bassil, Christopher F, Anderson, Gray R, Mayro, Benjamin, Askin, Kayleigh N, Winter, Peter S, Gruber, Samuel, Hall, Tierney M, Hoj, Jacob P, Cerda-Smith, Christian, Hutchinson, Haley M, Killarney, Shane T, Singleton, Katherine R, Li, Qin, Jubien-Girard, Kévin, Favreau, Cécile, Martin, Anthony R, Guillaume, Robert, Benhida, Rachid, Auberger, Patrick, Pendergast, Ann Marie, Lonard, David M, Puissant, Alexandre, Wood, Kris C
Published in bioRxiv (19.01.2023)
Published in bioRxiv (19.01.2023)
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MCB-613 exploits a collateral sensitivity in drug resistant EGFR -mutant non-small cell lung cancer through covalent inhibition of KEAP1
Bassil, Christopher F, Anderson, Gray R, Mayro, Benjamin, Askin, Kayleigh N, Winter, Peter S, Gruber, Samuel, Hall, Tierney M, Hoj, Jacob P, Cerda-Smith, Christian, Hutchinson, Haley M, Killarney, Shane T, Singleton, Katherine R, Qin, Li, Jubien-Girard, Kévin, Favreau, Cécile, Martin, Anthony R, Robert, Guillaume, Benhida, Rachid, Auberger, Patrick, Pendergast, Ann Marie, Lonard, David M, Puissant, Alexandre, Wood, Kris C
Published in bioRxiv : the preprint server for biology (19.01.2023)
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Published in bioRxiv : the preprint server for biology (19.01.2023)
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