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Efficacy and Safety of Firibastat, A First-in-Class Brain Aminopeptidase A Inhibitor, in Hypertensive Overweight Patients of Multiple Ethnic Origins: A Phase 2, Open-Label, Multicenter, Dose-Titrating Study
Ferdinand, Keith C., Balavoine, Fabrice, Besse, Bruno, Black, Henry R., Desbrandes, Stephanie, Dittrich, Howard C., Nesbitt, Shawna D.
Published in Circulation (New York, N.Y.) (09.07.2019)
Published in Circulation (New York, N.Y.) (09.07.2019)
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Endoplasmic reticulum aminopeptidase 2 regulates CD4+ T cells pyroptosis in rheumatoid arthritis
Zhang, Jianhua, Cai, Hao, Sun, Weiwei, Wu, Weijie, Nan, Yunyi, Ni, Yingchen, Wu, Xinyuan, Chen, Minhao, Xu, Hua, Wang, Youhua
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Published in Arthritis research & therapy (25.01.2024)
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Randomised, Double-Blind, Placebo-Controlled, Dose-Escalating Phase I Study of QGC001, a Centrally Acting Aminopeptidase A Inhibitor Prodrug
Balavoine, Fabrice, Azizi, Michel, Bergerot, Damien, De Mota, Nadia, Patouret, Rémi, Roques, Bernard P., Llorens-Cortes, Catherine
Published in Clinical pharmacokinetics (01.04.2014)
Published in Clinical pharmacokinetics (01.04.2014)
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Changes in soil enzymatic activity in a P-limited Mediterranean shrubland subject to experimental nitrogen deposition
Zuccarini, Paolo, Asensio, Dolores, Sardans, Jordi, Ogaya, Romà, Peñuelas, Josep
Published in Applied soil ecology : a section of Agriculture, ecosystems & environment (01.12.2021)
Published in Applied soil ecology : a section of Agriculture, ecosystems & environment (01.12.2021)
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A functional XPNPEP2 promoter haplotype leads to reduced plasma aminopeptidase P and increased risk of ACE inhibitor-induced angioedema
Cilia La Corte, Amy L., Carter, Angela M., Rice, Gillian I., Duan, Qing Ling, Rouleau, Guy A, Adam, Albert, Grant, Peter J., Hooper, Nigel M.
Published in Human mutation (01.11.2011)
Published in Human mutation (01.11.2011)
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Endoplasmic Reticulum Associated Aminopeptidase 2 (ERAP2) Is Released in the Secretome of Activated MDMs and Reduces in vitro HIV-1 Infection
Saulle, Irma, Ibba, Salomè Valentina, Torretta, Enrica, Vittori, Cecilia, Fenizia, Claudio, Piancone, Federica, Minisci, Davide, Lori, Elisa Maria, Trabattoni, Daria, Gelfi, Cecilia, Clerici, Mario, Biasin, Mara
Published in Frontiers in immunology (16.07.2019)
Published in Frontiers in immunology (16.07.2019)
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Root hairs and protein addition to soil promote leucine aminopeptidase activity of Hordeum vulgare L
Greenfield, Lucy M., Razavi, Bahar S., Bilyera, Nataliya, Zhang, Xuechen, Jones, Davey L.
Published in Rhizosphere (01.06.2021)
Published in Rhizosphere (01.06.2021)
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EMITT-1: Proof-of-mechanism immunopeptidome (ImPD) effects at target PK exposure, in a phase 1 study of GRWD5769 (a first-in-class inhibitor of Endoplasmic Reticulum Aminopeptidase 1 [ERAP1]) in patients with solid malignancies
Kichenadasse, Ganessan, Liu, Jia (Jenny), Hernandez Guerrero, Tatiana, Calvo, Emiliano, Jakobsson, Haakan, Moreno, Victor, Gan, Hui Kong, Joyce, Peter, Hyland, Natalie, Giovannetti, Mara, Palmer, Tanya, McAlpine, Cheryl, Green, Daniel, Symeonides, Stefan N.
Published in Journal of clinical oncology (01.06.2024)
Published in Journal of clinical oncology (01.06.2024)
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Endoplasmic reticulum aminopeptidase 2 gene single nucleotide polymorphisms in association with susceptibility to ankylosing spondylitis in an Iranian population
Ebrazeh, Mehrdad, Nojavan, Mohammad, Abdi-Shayan, Shiva, Salimifard, Sevda, Dolatshahi, Elahe, Aslani, Saeed, Hemmatzadeh, Maryam, Babaie, Farhad, Ghanavatinejad, Alireza, Azizi, Gholamreza, Jadidi-Niaragh, Farhad, Zamani, Neda, Mohammadi, Hamed
Published in Immunology letters (01.07.2020)
Published in Immunology letters (01.07.2020)
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Plasma renin–angiotensin system-regulating aminopeptidase activities are modified in early stage Alzheimer's disease and show gender differences but are not related to apolipoprotein E genotype
Puertas, María del Carmen, Martínez-Martos, José Manuel, Cobo, Manuela, Lorite, Pedro, Sandalio, Rosa María, Palomeque, Teresa, Torres, María Isabel, Carrera-González, María Pilar, Mayas, María Dolores, Ramírez-Expósito, María Jesús
Published in Experimental gerontology (01.06.2013)
Published in Experimental gerontology (01.06.2013)
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Role of glutamine-169 in the substrate recognition of human aminopeptidase B
Ogawa, Yuko, Ohnishi, Atsushi, Goto, Yoshikuni, Sakuma, Yoshiki, Watanabe, Jobu, Hattori, Akira, Tsujimoto, Masafumi
Published in Biochimica et biophysica acta (01.06.2014)
Published in Biochimica et biophysica acta (01.06.2014)
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Efficacy and Safety of Firibastat, A First-in-Class Brain Aminopeptidase A Inhibitor, in Hypertensive Overweight Patients of Multiple Ethnic Origins
Ferdinand, Keith C, Balavoine, Fabrice, Besse, Bruno, Black, Henry R, Desbrandes, Stephanie, Dittrich, Howard C, Nesbitt, Shawna D
Published in Circulation (New York, N.Y.) (09.07.2019)
Published in Circulation (New York, N.Y.) (09.07.2019)
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Altered Serum Oxytocinase and Enkephalin-Degrading Aminopeptidase Activities in Patients With Fibromyalgia
Martínez-Martos, José Manuel, Correa-Rodríguez, María, Rus, Alma, Molina, Francisco, Ramírez-Expósito, María Jesús, Aguilar-Ferrandiz, María Encarnación
Published in Biological research for nursing (01.07.2019)
Published in Biological research for nursing (01.07.2019)
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