Host factor SAMHD1 restricts DNA viruses in non-dividing myeloid cells
Hollenbaugh, Joseph A, Gee, Peter, Baker, Jonathon, Daly, Michele B, Amie, Sarah M, Tate, Jessica, Kasai, Natsumi, Kanemura, Yuka, Kim, Dong-Hyun, Ward, Brian M, Koyanagi, Yoshio, Kim, Baek
Published in PLoS pathogens (01.06.2013)
Published in PLoS pathogens (01.06.2013)
Get full text
Journal Article
SAMHD1 restricts HIV-1 infection in dendritic cells (DCs) by dNTP depletion, but its expression in DCs and primary CD4+ T-lymphocytes cannot be upregulated by interferons
St Gelais, Corine, de Silva, Suresh, Amie, Sarah M, Coleman, Christopher M, Hoy, Heather, Hollenbaugh, Joseph A, Kim, Baek, Wu, Li
Published in Retrovirology (11.12.2012)
Published in Retrovirology (11.12.2012)
Get full text
Journal Article
GTP Is the Primary Activator of the Anti-HIV Restriction Factor SAMHD1
Amie, Sarah M., Bambara, Robert A., Kim, Baek
Published in The Journal of biological chemistry (30.08.2013)
Published in The Journal of biological chemistry (30.08.2013)
Get full text
Journal Article
p21-mediated RNR2 repression restricts HIV-1 replication in macrophages by inhibiting dNTP biosynthesis pathway
Allouch, Awatef, David, Annie, Amie, Sarah M, Lahouassa, Hichem, Chartier, Loïc, Margottin-Goguet, Florence, Barré-Sinoussi, Françoise, Kim, Baek, Sáez-Cirión, Asier, Pancino, Gianfranco
Published in Proceedings of the National Academy of Sciences - PNAS (15.10.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (15.10.2013)
Get full text
Journal Article
Contribution of SAM and HD domains to retroviral restriction mediated by human SAMHD1
White, Tommy E, Brandariz-Nuñez, Alberto, Valle-Casuso, Jose Carlos, Amie, Sarah, Nguyen, Laura, Kim, Baek, Brojatsch, Jurgen, Diaz-Griffero, Felipe
Published in Virology (New York, N.Y.) (05.02.2013)
Published in Virology (New York, N.Y.) (05.02.2013)
Get full text
Journal Article
Anti-HIV Host Factor SAMHD1 Regulates Viral Sensitivity to Nucleoside Reverse Transcriptase Inhibitors via Modulation of Cellular Deoxyribonucleoside Triphosphate (dNTP) Levels
Amie, Sarah M., Daly, Michele B., Noble, Erin, Schinazi, Raymond F., Bambara, Robert A., Kim, Baek
Published in The Journal of biological chemistry (12.07.2013)
Published in The Journal of biological chemistry (12.07.2013)
Get full text
Journal Article
Evidence for IFNα-induced, SAMHD1-independent inhibitors of early HIV-1 infection
Goujon, Caroline, Schaller, Torsten, Galão, Rui Pedro, Amie, Sarah M, Kim, Baek, Olivieri, Kevin, Neil, Stuart J D, Malim, Michael H
Published in Retrovirology (25.02.2013)
Published in Retrovirology (25.02.2013)
Get full text
Journal Article
Reply to Pauls et al.: p21 is a master regulator of HIV replication in macrophages through dNTP synthesis block
Allouch, Awatef, David, Annie, Amie, Sarah M, Lahouassa, Hichem, Chartier, Loïc, Margottin-Goguet, Florence, Barré-Sinoussi, Françoise, Kim, Baek, Sáez-Cirión, Asier, Pancino, Gianfranco
Published in Proceedings of the National Academy of Sciences - PNAS (08.04.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (08.04.2014)
Get full text
Journal Article
GRK2 Activation by Receptors: Role of the Kinase Large Lobe and Carboxyl-Terminal Tail
Sterne-Marr, Rachel, Leahey, P. Alex, Bresee, Jamee E, Dickson, Heather M, Ho, Wesley, Ragusa, Michael J, Donnelly, Ryan M, Amie, Sarah M, Krywy, Janet A, Brookins-Danz, Elizabeth D, Orakwue, Somtochukwu C, Carr, Michael J, Yoshino-Koh, Kae, Li, Qianzhi, Tesmer, John J. G
Published in Biochemistry (Easton) (26.05.2009)
Published in Biochemistry (Easton) (26.05.2009)
Get full text
Journal Article
The Retroviral Restriction Ability of SAMHD1, but Not Its Deoxynucleotide Triphosphohydrolase Activity, Is Regulated by Phosphorylation
White, Tommy E., Brandariz-Nuñez, Alberto, Valle-Casuso, Jose Carlos, Amie, Sarah, Nguyen, Laura Anh, Kim, Baek, Tuzova, Marina, Diaz-Griffero, Felipe
Published in Cell host & microbe (17.04.2013)
Published in Cell host & microbe (17.04.2013)
Get full text
Journal Article
GTP is the primary activator of the anti-HIV restriction factor SAMHD1
Amie, Sarah M., Bambara, Robert A., Kim, Baek
Published in The Journal of biological chemistry (13.06.2014)
Published in The Journal of biological chemistry (13.06.2014)
Get full text
Journal Article
Anti-HIV host factor SAMHD1 regulates viral sensitivity to nucleoside reverse transcriptase inhibitors via modulation of cellular deoxyribonucleoside triphosphate (dNTP) levels
Amie, Sarah M., Daly, Michele B., Noble, Erin, Schinazi, Raymond F., Bambara, Robert A., Kim, Baek
Published in The Journal of biological chemistry (13.06.2014)
Published in The Journal of biological chemistry (13.06.2014)
Get full text
Journal Article
Contribution of oligomerization to the anti-HIV-1 properties of SAMHD1
Brandariz-Nuñez, Alberto, Valle-Casuso, Jose Carlos, White, Tommy E, Nguyen, Laura, Bhattacharya, Akash, Wang, Zhonghua, Demeler, Borries, Amie, Sarah, Knowlton, Caitlin, Kim, Baek, Ivanov, Dmitri N, Diaz-Griffero, Felipe
Published in Retrovirology (12.11.2013)
Published in Retrovirology (12.11.2013)
Get full text
Journal Article
p21-mediated RNR2 repression restricts HIV-1 replication in macrophages by inhibiting dNTP biosynthesis pathway
Allouch, Awatef, David, Annie, Amie, Sarah M., Lahouassa, Hichem, Chartier, Loïc, Margottin-Goguet, Florence, Barré-Sinoussi, Françoise, Kim, Baek, Sáez-Cirión, Asier, Pancino, Gianfranco
Published in Proceedings of the National Academy of Sciences - PNAS (15.10.2013)
Get full text
Published in Proceedings of the National Academy of Sciences - PNAS (15.10.2013)
Journal Article
Host Factor SAMHD1 Restricts DNA Viruses in Non-Dividing Myeloid Cells: e1003481
Hollenbaugh, Joseph A, Gee, Peter, Baker, Jonathon, Daly, Michele B, Amie, Sarah M, Tate, Jessica, Kasai, Natsumi, Kanemura, Yuka, Kim, Dong-Hyun, Ward, Brian M, Koyanagi, Yoshio, Kim, Baek
Published in PLoS pathogens (01.06.2013)
Published in PLoS pathogens (01.06.2013)
Get full text
Journal Article
RNR2 repression by p21 restricts reverse transcription of HIV-1 and related-lentiviruses in macrophages
Allouch, Awatef, David, Annie, Amie, Sarah, Lahouassa, Hichem, Chartier, Loic, Margottin-Goguet, Florence, Barré-Sinoussi, Françoise, Kim, Baek, Saez-Cirion, Asier, Pancino, Gianfranco
Published in Retrovirology (19.09.2013)
Published in Retrovirology (19.09.2013)
Get full text
Journal Article
Evidence for IFN[alpha]-induced, SAMHD1-independent inhibitors of early HIV-1 infection
Goujon, Caroline, Schaller, Torsten, Galão, Rui Pedro, Amie, Sarah M, Kim, Baek, Olivieri, Kevin, Neil, Stuart JD, Malim, Michael H
Published in Retrovirology (25.02.2013)
Published in Retrovirology (25.02.2013)
Get full text
Journal Article
SAMHD1 restricts HIV-1 infection in dendritic cells (DCs) by dNTP depletion, but its expression in DCs and primary CD4 super(+) T-lymphocytes cannot be upregulated by interferons
St Gelais, Corine, de Silva, Suresh, Amie, Sarah M, Coleman, Christopher M, Hoy, Heather, Hollenbaugh, Joseph A, Kim, Baek, Wu, Li
Published in Retrovirology (01.01.2012)
Published in Retrovirology (01.01.2012)
Get full text
Journal Article