Translational findings for odronextamab: From preclinical research to a first‐in‐human study in patients with CD20+ B‐cell malignancies
Zhu, Min, Olson, Kara, Kirshner, Jessica R., Khaksar Toroghi, Masood, Yan, Hong, Haber, Lauric, Meagher, Craig, Flink, Dina M., Ambati, Srikanth R., Davis, John D., DiCioccio, A. Thomas, Smith, Eric J., Retter, Marc W.
Published in Clinical and translational science (01.04.2022)
Published in Clinical and translational science (01.04.2022)
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Journal Article
Molecular assessment of intratumoral immune cell subsets and potential mechanisms of resistance to odronextamab, a CD20×CD3 bispecific antibody, in patients with relapsed/refractory B-cell non-Hodgkin lymphoma
Brouwer-Visser, Jurriaan, Fiaschi, Nathalie, Deering, Raquel P, Cygan, Kamil J, Scott, Darius, Jeong, Se, Boucher, Lauren, Gupta, Namita T, Gupta, Suraj, Adler, Christina, Topp, Max S, Bannerji, Rajat, Duell, Johannes, Advani, Ranjana H, Flink, Dina M, Chaudhry, Aafia, Thurston, Gavin, Ambati, Srikanth R, Jankovic, Vladimir
Published in Journal for immunotherapy of cancer (21.03.2024)
Published in Journal for immunotherapy of cancer (21.03.2024)
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Journal Article
Odronextamab, a human CD20×CD3 bispecific antibody in patients with CD20-positive B-cell malignancies (ELM-1): results from the relapsed or refractory non-Hodgkin lymphoma cohort in a single-arm, multicentre, phase 1 trial
Bannerji, Rajat, Arnason, Jon E, Advani, Ranjana H, Brown, Jennifer R, Allan, John N, Ansell, Stephen M, Barnes, Jeffrey A, O'Brien, Susan M, Chávez, Julio C, Duell, Johannes, Rosenwald, Andreas, Crombie, Jennifer L, Ufkin, Melanie, Li, Jingjin, Zhu, Min, Ambati, Srikanth R, Chaudhry, Aafia, Lowy, Israel, Topp, Max S
Published in The Lancet. Haematology (01.05.2022)
Published in The Lancet. Haematology (01.05.2022)
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Journal Article
Complete responses to odronextamab in two patients with diffuse large B‐cell lymphoma refractory to chimeric antigen receptor T‐cell therapy
Weinstock, Matt, Elavalakanar, Pavania, Bright, Susan, Ambati, Srikanth R., Brouwer‐Visser, Jurriaan, Pourpe, Stephane, Fiaschi, Nathalie, Jankovic, Vladimir, Thurston, Gavin, Deering, Raquel P., Chaudhry, Aafia, Joyce, Robin, Arnason, Jon
Published in British journal of haematology (01.11.2022)
Published in British journal of haematology (01.11.2022)
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Journal Article
Recapitulating the Size and Cargo of Tumor Exosomes in a Tissue-Engineered Model
Villasante, Aranzazu, Marturano-Kruik, Alessandro, Ambati, Srikanth R, Liu, Zen, Godier-Furnemont, Amandine, Parsa, Hesam, Lee, Benjamin W, Moore, Malcolm A S, Vunjak-Novakovic, Gordana
Published in Theranostics (01.01.2016)
Published in Theranostics (01.01.2016)
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Pre-clinical efficacy of PU-H71, a novel HSP90 inhibitor, alone and in combination with bortezomib in Ewing sarcoma
Ambati, Srikanth R., Lopes, Eloisi Caldas, Kosugi, Kohji, Mony, Ullas, Zehir, Ahmet, Shah, Smit K., Taldone, Tony, Moreira, Andre L., Meyers, Paul A., Chiosis, Gabriela, Moore, Malcolm A.S.
Published in Molecular oncology (01.03.2014)
Published in Molecular oncology (01.03.2014)
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Journal Article
Plasma DNA-based molecular diagnosis, prognostication, and monitoring of patients with EWSR1 fusion-positive sarcomas
Shukla, Neerav N, Patel, Juber A, Magnan, Heather, Zehir, Ahmet, You, Daoqi, Tang, Jiabin, Meng, Fanli, Samoila, Aliaksandra, Slotkin, Emily K, Ambati, Srikanth R, Chou, Alexander J, Wexler, Leonard H, Meyers, Paul A, Peerschke, Ellinor I, Viale, Agnes, Berger, Michael F, Ladanyi, Marc
Published in JCO precision oncology (01.01.2017)
Published in JCO precision oncology (01.01.2017)
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Journal Article
BO-1055, a novel DNA cross-linking agent with remarkable low myelotoxicity shows potent activity in sarcoma models
Ambati, Srikanth R, Shieh, Jae-Hung, Pera, Benet, Lopes, Eloisi Caldas, Chaudhry, Anisha, Wong, Elissa W P, Saxena, Ashish, Su, Tsann-Long, Moore, Malcolm A S
Published in Oncotarget (12.07.2016)
Published in Oncotarget (12.07.2016)
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Journal Article
Intracardiac Low-grade Sarcoma Following Treatment for Ewing Sarcoma
Ortiz, Michael V, Magnan, Heather, Slotkin, Emily K, Ambati, Srikanth R, Chou, Alexander J, Wexler, Leonard H, Meyers, Paul A, Walsh, Michael F, Heaton, Todd, Girardi, Leonard N, Wolden, Suzanne L, Price, Anita P, Kennedy, Jennifer A, Zehir, Ahmet, Hameed, Meera, Berger, Michael F, Kentsis, Alex, Shukla, Neerav
Published in Journal of pediatric hematology/oncology (01.11.2017)
Published in Journal of pediatric hematology/oncology (01.11.2017)
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Journal Article
Longitudinal monitoring of cardiac siderosis using cardiovascular magnetic resonance T2 in patients with thalassemia major on various chelation regimens: A 6‐year study
Ambati, Srikanth R., Randolph, Rachel E., Mennitt, Kevin, Kleinert, Dorothy A., Weinsaft, Jonathan W., Giardina, Patricia J.
Published in American journal of hematology (01.08.2013)
Published in American journal of hematology (01.08.2013)
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Journal Article
Superior vena cava syndrome in children
Gupta, Vineeta, Ambati, Srikanth R., Pant, P., Bhatia, Baldev
Published in Indian journal of hematology & blood transfusion (01.03.2008)
Published in Indian journal of hematology & blood transfusion (01.03.2008)
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Journal Article
Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers
Kim, Han Sang, Bojmar, Linda, Gyan, Kofi Ennu, Cioffi, Michele, Hernandez, Jonathan, Rodrigues, Gonçalo, Molina, Henrik, Heissel, Søren, Mark, Milica Tesic, Benito-Martin, Alberto, Lucotti, Serena, Di Giannatale, Angela, Offer, Katharine, Williams, Caitlin, Nogués, Laura, Davies, Alexander E., Kenific, Candia M., Buehring, Weston, Lauritzen, Pernille, Ogitani, Yusuke, Sugiura, Kei, Takahashi, Naoko, Alečković, Maša, Bailey, Kayleen A., Jolissant, Joshua S., Harris, Ashton, Schaeffer, L. Miles, García-Santos, Guillermo, Posner, Zoe, Balachandran, Vinod P., Raju, G. Praveen, Scherz, Avigdor, Sagi, Irit, Scherz-Shouval, Ruth, Yarden, Yosef, Oren, Moshe, Malladi, Mahathi, Petriccione, Mary, De Braganca, Kevin C., Donzelli, Maria, Fischer, Cheryl, Vitolano, Stephanie, Wright, Geraldine P., Ganshaw, Lee, Ahmed, Amina, DeStefano, Joe, Roehrl, Michael H.A., Lacayo, Norman J., Weiser, Martin R., Brady, Mary S., Meyers, Paul A., Ambati, Srikanth R., Chou, Alexander J., Slotkin, Emily K., Modak, Shakeel, Roberts, Stephen S., Basu, Ellen M., Diolaiti, Daniel, Krantz, Benjamin A., Cardoso, Fatima, Simpson, Amber L., Berger, Michael, Rudin, Charles M., Simeone, Diane M., Jain, Maneesh, Ghajar, Cyrus M., Batra, Surinder K., Stanger, Ben Z., Brown, Kristy A., Rajasekhar, Vinagolu K., Healey, John H., de Sousa, Maria, Kramer, Kim, Sheth, Sujit, Baisch, Jeanine, Pascual, Virginia, Heaton, Todd E., La Quaglia, Michael P., Pisapia, David J., Schwartz, Robert, Liu, Yuan, Shukla, Arti, Blavier, Laurence, DeClerck, Yves A., Bissell, Mina J., Caffrey, Thomas C., Grandgenett, Paul M., Hollingsworth, Michael A., Bromberg, Jacqueline, Costa-Silva, Bruno, Peinado, Hector, Kang, Yibin, Garcia, Benjamin A., O’Reilly, Eileen M., Kelsen, David, Trippett, Tanya M., Jones, David R., Matei, Irina R., Jarnagin, William R., Lyden, David
Published in Cell (20.08.2020)
Published in Cell (20.08.2020)
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Journal Article
Evaluate Dynamics of IL-6 Release during Step-up Dosing of Subcutaneous Administration of Odronextamab Via a Quantitative Systems Pharmacology Modeling Approach
Khaksar Toroghi, Masood, Zhu, Min, Ambati, Srikanth R., Mohamed, Hesham, Chaudhry, Aafia, Yan, Hong, Davis, John D., DiCioccio, A. Thomas
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
Selection of Odronextamab Pediatric Dosing Regimens for Aggressive Non-Hodgkin Lymphoma Via a Modeling and Simulation Approach
Zhu, Min, Dodds, Michael, Ambati, Srikanth R., Mohamed, Hesham, Chittenden, Jason, Yan, Hong, Chaudhry, Aafia, Davis, John D.
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
Modeling and Simulation in Support of Odronextamab Subcutaneous Dose Selection for Adult Patients with Indolent or Aggressive Non-Hodgkin Lymphoma
Zhu, Min, Ambati, Srikanth R., Mohamed, Hesham, Khaksar Toroghi, Masood, Yan, Hong, Chaudhry, Aafia, Davis, John D.
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
Incidence of any infections and SARS-CoV-2 infections in patients receiving treatment for follicular lymphoma and diffuse large B-cell lymphoma: Real-world evidence from a large US national claims database
Omofuma, Omonefe O., Breskin, Alexander, Shao, Ping, Asubonteng, Julius, Archambault, Alexi N., Hampp, Christian, Shariff, Saleem, Hearnden, Claire, Ambati, Srikanth R., Mohamed, Hesham
Published in Journal of clinical oncology (01.06.2024)
Published in Journal of clinical oncology (01.06.2024)
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Journal Article
A Quantitative Systems Pharmacology Modeling Framework for Evaluation of Cytokine Release Mediated By Intravenous Odronextamab Monotherapy in Patients with B-Cell Non-Hodgkin Lymphoma
Khaksar Toroghi, Masood, Zhu, Min, Brouwer-Visser, Jurriaan, Ambati, Srikanth R., Mohamed, Hesham, Chaudhry, Aafia, Davis, John D., DiCioccio, A. Thomas
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
Real-world treatment patterns among patients with diffuse large B-cell lymphoma (DLBCL) treated with CD19-directed chimeric antigen receptor T-cell therapy (CAR T)
Jalbert, Jessica J., Arnason, Jon E., Ge, Wenzhen, Chen, Chieh-I, Ambati, Srikanth R., Wu, Ning, Chaudhry, Aafia
Published in Journal of clinical oncology (20.05.2020)
Published in Journal of clinical oncology (20.05.2020)
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Journal Article