Targeting the CXCR4 pathway using a novel anti-CXCR4 IgG1 antibody (PF-06747143) in chronic lymphocytic leukemia
Kashyap, Manoj K, Amaya-Chanaga, Carlos I, Kumar, Deepak, Simmons, Brett, Huser, Nanni, Gu, Yin, Hallin, Max, Lindquist, Kevin, Yafawi, Rolla, Choi, Michael Y, Amine, Ale-Ali, Rassenti, Laura Z, Zhang, Cathy, Liu, Shu-Hui, Smeal, Tod, Fantin, Valeria R, Kipps, Thomas J, Pernasetti, Flavia, Castro, Januario E
Published in Journal of hematology and oncology (19.05.2017)
Published in Journal of hematology and oncology (19.05.2017)
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Ibrutinib plus Obinutuzumab as Frontline Therapy for Chronic Lymphocytic Leukemia Is Associated with a Lower Rate of Infusion-Related Reactions and with Sustained Remissions after Ibrutinib Discontinuation: A Single-Arm, Open-Label, Phase 1b/2 Clinical Trial NCT0231576
Castro, Januario E., Lengerke-Diaz, Paula A., Velez Lujan, Juliana, Choi, Michael Y., Moreno-Cortes, Eider F., Forero, Jose V., Garcia-Robledo, Juan Esteban, Jacobs, Chaja, McCarthy, Colin, Heinen, Alaina, Amaya-Chanaga, Carlos I., Kipps, Thomas J.
Published in Advances in Hematology (22.01.2022)
Published in Advances in Hematology (22.01.2022)
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Ulocuplumab (BMS-936564 / MDX1338): a fully human anti-CXCR4 antibody induces cell death in chronic lymphocytic leukemia mediated through a reactive oxygen species-dependent pathway
Kashyap, Manoj K, Kumar, Deepak, Jones, Harrison, Amaya-Chanaga, Carlos I, Choi, Michael Y, Melo-Cardenas, Johanna, Ale-Ali, Amine, Kuhne, Michelle R, Sabbatini, Peter, Cohen, Lewis J, Shelat, Suresh G, Rassenti, Laura Z, Kipps, Thomas J, Cardarelli, Pina M, Castro, Januario E
Published in Oncotarget (19.01.2016)
Published in Oncotarget (19.01.2016)
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Prognostic Testing and Treatment Patterns in Chronic Lymphocytic Leukemia in the Era of Novel Targeted Therapies: Results From the informCLL Registry
Mato, Anthony R., Barrientos, Jacqueline C., Ghosh, Nilanjan, Pagel, John M., Brander, Danielle M., Gutierrez, Meghan, Kadish, Karen, Tomlinson, Brian, Iyengar, Reethi, Ipe, David, Upasani, Sandhya, Amaya-Chanaga, Carlos I., Sundaram, Murali, Han, Jennifer, Giafis, Nick, Sharman, Jeff P.
Published in Clinical lymphoma, myeloma and leukemia (01.03.2020)
Published in Clinical lymphoma, myeloma and leukemia (01.03.2020)
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Using ibrutinib in earlier lines of treatment results in better outcomes for patients with chronic lymphocytic leukemia/small lymphocytic lymphoma
Woyach, Jennifer, Tedeschi, Alessandra, Munir, Talha, Siddiqi, Tanya, Hillmen, Peter, Byrd, John C., Ghia, Paolo, Mulligan, Stephen P., Dai, Sandra, Amaya-Chanaga, Carlos I., Dean, James P., O'Brien, Susan M., Barr, Paul M.
Published in Leukemia & lymphoma (10.11.2021)
Published in Leukemia & lymphoma (10.11.2021)
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Long-Term Sustained Responses Following Ibrutinib Discontinuation after Frontline Therapy with Obinutuzumab Plus Ibrutinib in Patients with Chronic Lymphocytic Leukemia
Lengerke Diaz, Paula A., Choi, Michael Y., Moreno Cortes, Eider F., Forero, Jose V., Velez-Lujan, Juliana, Amaya-Chanaga, Carlos I., Kipps, Thomas, Castro, Januario E.
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
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Obinutuzumab (Gazyva) and High-Dose Methylprednisolone (HDMP) Combination for Patients with Chronic Lymphocytic Leukemia (CLL) - a Phase Ib/II Study
Castro, Januario E, Amaya-Chanaga, Carlos I., Velez Lujan, Juliana, Choi, Michael, McCarthy, Colin, Kipps, Thomas J.
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
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A Phase Ib/II Study of Combined Obinutuzumab (Gazyva) and High-Dose Methylprednisolone (HDMP) As Treatment for Patients with Chronic Lymphocytic Leukemia (CLL)
Castro, Januario E., Choi, Michael Y., Amaya-Chanaga, Carlos I., Nguyen, Natalie, MacCarthy, Colin, Kipps, Thomas J.
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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Journal Article
A Phase Ib/II Study of Combined Obinutuzumab and High-Dose Methylprednisolone (HDMP) As Treatment for Patients with Chronic Lymphocytic Leukemia (CLL)
Castro, Januario E., Choi, Michael Y., Amaya-Chanaga, Carlos I., Nguyen, Natalie, Ale-Ali, Amine, Kipps, Thomas J.
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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A Phase Ib/II Study of Ibrutinib in Combination with Obinutuzumab-Gazyva As First-Line Treatment for Patients with Chronic Lymphocytic Leukemia > 65 Years Old or with Coexisting Conditions
Amaya-Chanaga, Carlos I., Choi, Michael Y., Nguyen, Natalie, DeVore, Elizabeth, MacCarthy, Colin, Hilger-Rolfe, Jacqueline, Kipps, Thomas J., Castro, Januario E.
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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Journal Article
Targeting the CXCR4-CXCL12 Pathway Using an Anti-CXCR4 IgG1 Antibody (PF-06747143) in Chronic Lymphocytic Leukemia
Kashyap, Manoj K., Amaya-Chanaga, Carlos I., Kumar, Deepak, Choi, Michael Y., Rassenti, Laura Z., Ale-Ali, Amine, Liu, Shu-Hui, Smeal, Tod, Fantin, Valeria, Kipps, Thomas J., Pernasetti, Flavia, Castro, Januario E.
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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Journal Article
BMS-936564 (Anti-CXCR4 Antibody) Induces Specific Leukemia Cell Mobilization and Objective Clinical Responses In CLL Patients Treated Under a Phase I Clinical Trial
Kashyap, Manoj Kumar, Amaya-Chanaga, Carlos I., Jones, Harrison, AlMahasnah, Eiman A., Choi, Michael Y., Kuhne, Michelle R., Cohen, Lewis, Sabbatini, Peter, Kipps, Thomas J., Cardarelli, Pina M., Castro, Januario E.
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
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