The Janus kinase inhibitor JTE-052 improves skin barrier function through suppressing signal transducer and activator of transcription 3 signaling
Amano, Wataru, DVM, Nakajima, Saeko, MD, PhD, Kunugi, Hayato, PhD, Numata, Yasuharu, MS, Kitoh, Akihiko, MD, PhD, Egawa, Gyohei, MD, PhD, Dainichi, Teruki, MD, PhD, Honda, Tetsuya, MD, PhD, Otsuka, Atsushi, MD, PhD, Kimoto, Yukari, MS, Yamamoto, Yasuo, MS, Tanimoto, Atsuo, MS, Matsushita, Mutsuyoshi, PhD, Miyachi, Yoshiki, MD, PhD, Kabashima, Kenji, MD, PhD
Published in Journal of allergy and clinical immunology (01.09.2015)
Published in Journal of allergy and clinical immunology (01.09.2015)
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Journal Article
Macrophage polarization toward M1 phenotype in T cell transfer colitis model
Ebihara, Shin, Urashima, Toshiki, Amano, Wataru, Yamamura, Hideto, Konishi, Noriko
Published in BMC gastroenterology (27.11.2023)
Published in BMC gastroenterology (27.11.2023)
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Journal Article
IL-17A as an Inducer for Th2 Immune Responses in Murine Atopic Dermatitis Models
Nakajima, Saeko, Kitoh, Akihiko, Egawa, Gyohei, Natsuaki, Yohei, Nakamizo, Satoshi, Moniaga, Catharina Sagita, Otsuka, Atsushi, Honda, Tetsuya, Hanakawa, Sho, Amano, Wataru, Iwakura, Yoichiro, Nakae, Susumu, Kubo, Masato, Miyachi, Yoshiki, Kabashima, Kenji
Published in Journal of investigative dermatology (01.08.2014)
Published in Journal of investigative dermatology (01.08.2014)
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Journal Article
Resolvin E1 inhibits dendritic cell migration in the skin and attenuates contact hypersensitivity responses
Sawada, Yu, Honda, Tetsuya, Hanakawa, Sho, Nakamizo, Satoshi, Murata, Teruasa, Ueharaguchi-Tanada, Yuri, Ono, Sachiko, Amano, Wataru, Nakajima, Saeko, Egawa, Gyohei, Tanizaki, Hideaki, Otsuka, Atsushi, Kitoh, Akihiko, Dainichi, Teruki, Ogawa, Narihito, Kobayashi, Yuichi, Yokomizo, Takehiko, Arita, Makoto, Nakamura, Motonobu, Miyachi, Yoshiki, Kabashima, Kenji
Published in The Journal of experimental medicine (19.10.2015)
Published in The Journal of experimental medicine (19.10.2015)
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Journal Article
Pituitary adenylate cyclase-activating polypeptide promotes cutaneous dendritic cell functions in contact hypersensitivity
Yamamoto, Yasuo, Otsuka, Atsushi, Ishida, Yoshihiro, Wong, Lai San, Seidel, Judith A., Nonomura, Yumi, Nakashima, Chisa, Nakajima, Saeko, Kitoh, Akihiko, Nomura, Takashi, Dainichi, Teruki, Honda, Tetsuya, Amano, Wataru, Konishi, Noriko, Hayashi, Mikio, Matsushita, Mutsuyoshi, Kabashima, Kenji
Published in Journal of allergy and clinical immunology (01.09.2021)
Published in Journal of allergy and clinical immunology (01.09.2021)
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Journal Article
The Active Site Cysteine of the Proapoptotic Protein Glyceraldehyde-3-phosphate Dehydrogenase Is Essential in Oxidative Stress-induced Aggregation and Cell Death
Nakajima, Hidemitsu, Amano, Wataru, Fujita, Akikazu, Fukuhara, Ayano, Azuma, Yasu-Taka, Hata, Fumiaki, Inui, Takashi, Takeuchi, Tadayoshi
Published in The Journal of biological chemistry (07.09.2007)
Published in The Journal of biological chemistry (07.09.2007)
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Journal Article
Glyceraldehyde-3-phosphate Dehydrogenase Aggregate Formation Participates in Oxidative Stress-induced Cell Death
Nakajima, Hidemitsu, Amano, Wataru, Kubo, Takeya, Fukuhara, Ayano, Ihara, Hideshi, Azuma, Yasu-Taka, Tajima, Hisao, Inui, Takashi, Sawa, Akira, Takeuchi, Tadayoshi
Published in The Journal of biological chemistry (04.12.2009)
Published in The Journal of biological chemistry (04.12.2009)
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Journal Article
JAK inhibitor JTE-052 regulates contact hypersensitivity by downmodulating T cell activation and differentiation
Amano, Wataru, Nakajima, Saeko, Yamamoto, Yasuo, Tanimoto, Atsuo, Matsushita, Mutsuyoshi, Miyachi, Yoshiki, Kabashima, Kenji, MD, PhD
Published in Journal of dermatological science (01.12.2016)
Published in Journal of dermatological science (01.12.2016)
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Journal Article
Decreased Filaggrin Level May Lead to Sweat Duct Obstruction in Filaggrin Mutant Mice
Rerknimitr, Pawinee, Tanizaki, Hideaki, Yamamoto, Yasuo, Amano, Wataru, Nakajima, Saeko, Nakashima, Chisa, Nonomura, Yumi, Wititsuwannakul, Jade, Miyachi, Yoshiki, Otsuka, Atsushi, Kabashima, Kenji
Published in Journal of investigative dermatology (01.01.2017)
Published in Journal of investigative dermatology (01.01.2017)
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Journal Article
Application of Piezoelectric PLLA Braided Cord as Wearable Sensor to Realize Monitoring System for Indoor Dogs with Less Physical or Mental Stress
Tajitsu, Yoshiro, Takarada, Jun, Hikichi, Tokiya, Sugii, Ryoji, Takatani, Kohei, Yanagimoto, Hiroki, Nakanishi, Riku, Shiomi, Seita, Kitamoto, Daiki, Nakiri, Takuo, Takeuchi, Osamu, Deguchi, Miki, Muto, Takanori, Kuroki, Kazuaki, Amano, Wataru, Misumi, Ayaka, Takahashi, Mitsuru, Sugiyama, Kazuki, Tanabe, Akira, Kamohara, Shiro, Nisho, Rei, Takeshita, Koji
Published in Micromachines (Basel) (05.01.2023)
Published in Micromachines (Basel) (05.01.2023)
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Journal Article
An aggregate-prone mutant of human glyceraldehyde-3-phosphate dehydrogenase augments oxidative stress-induced cell death in SH-SY5Y cells
Nakajima, Hidemitsu, Amano, Wataru, Fukuhara, Ayano, Kubo, Takeya, Misaki, Shouhei, Azuma, Yasu-Taka, Inui, Takashi, Takeuchi, Tadayoshi
Published in Biochemical and biophysical research communications (18.12.2009)
Published in Biochemical and biophysical research communications (18.12.2009)
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Journal Article
Janus kinase inhibitor delgocitinib suppresses pruritus and nerve elongation in an atopic dermatitis murine model
Yamamoto, Yasuo, Otsuka, Atsushi, Nakashima, Chisa, Ishida, Yoshihiro, Honda, Tetsuya, Egawa, Gyohei, Amano, Wataru, Usui, Kenji, Hamada, Yuji, Wada, Masashi, Tanimoto, Atsuo, Konishi, Noriko, Hayashi, Mikio, Matsushita, Mutsuyoshi, Kabashima, Kenji
Published in Journal of dermatological science (01.02.2020)
Published in Journal of dermatological science (01.02.2020)
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Journal Article
A novel JAK inhibitor JTE‐052 reduces skin inflammation and ameliorates chronic dermatitis in rodent models: Comparison with conventional therapeutic agents
Tanimoto, Atsuo, Shinozaki, Yuichi, Yamamoto, Yasuo, Katsuda, Yoshiaki, Taniai‐Riya, Eriko, Toyoda, Kaoru, Kakimoto, Kochi, Kimoto, Yukari, Amano, Wataru, Konishi, Noriko, Hayashi, Mikio
Published in Experimental dermatology (01.01.2018)
Published in Experimental dermatology (01.01.2018)
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Journal Article
DATA PROCESSING DEVICE, PROGRAM, DATA PROCESSING SYSTEM, AND DATA PROCESSING METHOD
AMANO WATARU, DEGUCHI MIKI, MISUMI AYAKA, MUTO TAKANORI, KUROKI KAZUAKI
Year of Publication 15.06.2023
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Year of Publication 15.06.2023
Patent
Pharmacological properties of JTE-052: a novel potent JAK inhibitor that suppresses various inflammatory responses in vitro and in vivo
Tanimoto, Atsuo, Ogawa, Yoshihiro, Oki, Chika, Kimoto, Yukari, Nozawa, Keisuke, Amano, Wataru, Noji, Satoru, Shiozaki, Makoto, Matsuo, Akira, Shinozaki, Yuichi, Matsushita, Mutsuyoshi
Published in Inflammation research (01.01.2015)
Published in Inflammation research (01.01.2015)
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Journal Article
Improvement of spontaneous locomotor activity with JAK inhibition by JTE-052 in rat adjuvant-induced arthritis
Tanimoto, Atsuo, Shinozaki, Yuichi, Nozawa, Keisuke, Kimoto, Yukari, Amano, Wataru, Matsuo, Akira, Yamaguchi, Takayuki, Matsushita, Mutsuyoshi
Published in BMC musculoskeletal disorders (06.11.2015)
Published in BMC musculoskeletal disorders (06.11.2015)
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Journal Article
Coronary risk factor management in primary practice in Shibuya, Tokyo
Nakamura, Jo, Amano, Wataru, Araki, You, Ishii, Kazuchika, Uchida, Yoshihiro, Kon, Toshio, Sato, Yasuo, Shiozaki, Masahide, Takada, Kazuko, Naito, Hirokuni, Nagaiwa, Jiro, Nakajima, Kiyotaka, Yoshida, Katsuya, Watanabe, Yutaka, Tomaru, Takanobu, Aoyagi, Teruhiko
Published in Journal of cardiology (01.11.2003)
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Published in Journal of cardiology (01.11.2003)
Journal Article
SKIN BARRIER FUNCTION IMPROVING AGENT
AMANO WATARU, TANIMOTO ATSUO, KIMOTO YUKARI, KABASHIMA KENJI, UEDA YOSHIFUMI
Year of Publication 04.12.2014
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Year of Publication 04.12.2014
Patent
FACILITY INSPECTION ASSISTANCE DEVICE
AMANO WATARU, MIURA HARUYOSHI, SAITO HITOSHI, TAKEMOTO TAKESHI, HONMA TAKESHI, HATAYAMA MASAMI, TAKEDA RYU
Year of Publication 12.05.2016
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Year of Publication 12.05.2016
Patent