Elective nodal irradiation mitigates local and systemic immunity generated by combination radiation and immunotherapy in head and neck tumors
Darragh, Laurel B, Gadwa, Jacob, Pham, Tiffany T, Van Court, Benjamin, Neupert, Brooke, Olimpo, Nicholas A, Nguyen, Khoa, Nguyen, Diemmy, Knitz, Michael W, Hoen, Maureen, Corbo, Sophia, Joshi, Molishree, Zhuang, Yonghua, Amann, Maria, Wang, Xiao-Jing, Dow, Steven, Kedl, Ross M, Samedi, Von, Boss, Mary-Keara, Karam, Sana D
Published in Nature communications (16.11.2022)
Published in Nature communications (16.11.2022)
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Journal Article
CD25 targeting with the afucosylated human IgG1 antibody RG6292 eliminates regulatory T cells and CD25+ blasts in acute myeloid leukemia
Pousse, Laurène, Korfi, Koorosh, Medeiros, Bruno C, Berrera, Marco, Kumpesa, Nadine, Eckmann, Jan, Hutter, Idil Karakoc, Griesser, Vera, Karanikas, Vaios, Klein, Christian, Amann, Maria
Published in Frontiers in oncology (02.05.2023)
Published in Frontiers in oncology (02.05.2023)
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Journal Article
Abstract 6135: Tumor-bearing non-human primates: An unrivaled model for translational cancer immunology research
Ceppi, Maurizio, Hettich, Michael, Teichgräber, Volker, Driessen, Wouter, Tuerck, Dietrich, Marrer-Berger, Estelle, Evers, Stefan, Crameri, Flavio, Gomes, Bruno, Bachl, Jürgen, Klein, Christian, Claus, Christina, Amann, Maria, Krieter, Oliver, Dugan, Greg, Caudell, David, Grayson, Jason, Kiran, Sai Kumar Solingapuram, Cline, Mark
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Fibroblast activation protein-targeted-4-1BB ligand agonist amplifies effector functions of intratumoral T cells in human cancer
Trüb, Marta, Uhlenbrock, Franziska, Claus, Christina, Herzig, Petra, Thelen, Martin, Karanikas, Vaios, Bacac, Marina, Amann, Maria, Albrecht, Rosemarie, Ferrara-Koller, Claudia, Thommen, Daniela, Rothschield, Sacha, Savic Prince, Spasenija, Mertz, Kirsten D, Cathomas, Gieri, Rosenberg, Robert, Heinzelmann-Schwarz, Viola, Wiese, Mark, Lardinois, Didier, Umana, Pablo, Klein, Christian, Laubli, Heinz, Kashyap, Abhishek S, Zippelius, Alfred
Published in Journal for immunotherapy of cancer (01.07.2020)
Published in Journal for immunotherapy of cancer (01.07.2020)
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Journal Article
Experimental blunt chest trauma-induced myocardial inflammation and alteration of gap-junction protein connexin 43
Kalbitz, Miriam, Amann, Elisa Maria, Bosch, Belinda, Palmer, Annette, Schultze, Anke, Pressmar, Jochen, Weber, Birte, Wepler, Martin, Gebhard, Florian, Schrezenmeier, Hubert, Brenner, Rolf, Huber-Lang, Markus
Published in PloS one (09.11.2017)
Published in PloS one (09.11.2017)
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Journal Article
Inflammatory response of mesenchymal stromal cells after in vivo exposure with selected trauma-related factors and polytrauma serum
Amann, Elisa Maria, Groß, Alexander, Rojewski, Markus Thomas, Kestler, Hans Armin, Kalbitz, Miriam, Brenner, Rolf Erwin, Huber-Lang, Markus, Schrezenmeier, Hubert
Published in PloS one (14.05.2019)
Published in PloS one (14.05.2019)
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Journal Article
Effect of High-Dose Irradiation on Human Bone-Marrow-Derived Mesenchymal Stromal Cells
Fekete, Natalie, Erle, Alexander, Amann, Elisa Maria, Fürst, Daniel, Rojewski, Markus Thomas, Langonné, Alain, Sensebé, Luc, Schrezenmeier, Hubert, Schmidtke-Schrezenmeier, Gerlinde
Published in Tissue engineering. Part C, Methods (01.02.2015)
Published in Tissue engineering. Part C, Methods (01.02.2015)
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Journal Article
Alternatives to the use of fetal bovine serum: human platelet lysates as a serum substitute in cell culture media
Rauch, Caroline, Feifel, Elisabeth, Amann, Eva-Maria, Spötl, Hans Peter, Schennach, Harald, Pfaller, Walter, Gstraunthaler, Gerhard
Published in ALTEX, alternatives to animal experimentation (2011)
Published in ALTEX, alternatives to animal experimentation (2011)
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Journal Article
Tumor-targeted 4-1BB agonists for combination with T cell bispecific antibodies as off-the-shelf therapy
Claus, Christina, Ferrara, Claudia, Xu, Wei, Sam, Johannes, Lang, Sabine, Uhlenbrock, Franziska, Albrecht, Rosmarie, Herter, Sylvia, Schlenker, Ramona, Hüsser, Tamara, Diggelmann, Sarah, Challier, John, Mössner, Ekkehard, Hosse, Ralf J, Hofer, Thomas, Brünker, Peter, Joseph, Catherine, Benz, Jörg, Ringler, Philippe, Stahlberg, Henning, Lauer, Matthias, Perro, Mario, Chen, Stanford, Küttel, Christine, Bhavani Mohan, Preethi L, Nicolini, Valeria, Birk, Martina Carola, Ongaro, Amandine, Prince, Christophe, Gianotti, Reto, Dugan, Gregory, Whitlow, Christopher T, Solingapuram Sai, Kiran Kumar, Caudell, David L, Burgos-Rodriguez, Armando G, Cline, J Mark, Hettich, Michael, Ceppi, Maurizio, Giusti, Anna Maria, Crameri, Flavio, Driessen, Wouter, Morcos, Peter N, Freimoser-Grundschober, Anne, Levitsky, Victor, Amann, Maria, Grau-Richards, Sandra, von Hirschheydt, Thomas, Tournaviti, Stella, Mølhøj, Michael, Fauti, Tanja, Heinzelmann-Schwarz, Viola, Teichgräber, Volker, Colombetti, Sara, Bacac, Marina, Zippelius, Alfred, Klein, Christian, Umaña, Pablo
Published in Science translational medicine (12.06.2019)
Published in Science translational medicine (12.06.2019)
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Journal Article
Optimizing Early Clinical Investigations in Cancer Immunotherapy: The Translational Journey of RG6292, a Novel, Selective Treg-Depleting Antibody
Belli, Sara, Amann, Maria, Hutchinson, Lucy, Pousse, Laurène, Abdolzade-Bavil, Afsaneh, Justies, Nicole, Jacobsen, Bjoern, Ploix, Corinne, Tselempi, Eleni, Tosevski, Vinko, Koll, Hans, Schnetzler, Gabriel, Boetsch, Christophe, Marrer-Berger, Estelle
Published in Clinical pharmacology and therapeutics (01.09.2024)
Published in Clinical pharmacology and therapeutics (01.09.2024)
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Journal Article
CD25 Targeting Eliminates Regulatory T Cells and CD25+ Blasts in Acute Myeloid Leukemia
Pousse, Laurene, Medeiros, Bruno C., Korfi, Koorosh, Berrera, Marco, Kumpesa, Nadine, Griesser, Vera, Eckmann, Jan, Karanikas, Vaios, Klein, Christian, Amann, Maria
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
Simultaneous targeting of PD-1 and IL-2Rβγ with radiation therapy inhibits pancreatic cancer growth and metastasis
Piper, Miles, Hoen, Maureen, Darragh, Laurel B., Knitz, Michael W., Nguyen, Diemmy, Gadwa, Jacob, Durini, Greta, Karakoc, Idil, Grier, Abby, Neupert, Brooke, Van Court, Benjamin, Abdelazeem, Khalid N.M., Yu, Justin, Olimpo, Nicholas A., Corbo, Sophia, Ross, Richard Blake, Pham, Tiffany T., Joshi, Molishree, Kedl, Ross M., Saviola, Anthony J., Amann, Maria, Umaña, Pablo, Codarri Deak, Laura, Klein, Christian, D’Alessandro, Angelo, Karam, Sana D.
Published in Cancer cell (08.05.2023)
Published in Cancer cell (08.05.2023)
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Journal Article
Preclinical models for prediction of immunotherapy outcomes and immune evasion mechanisms in genetically heterogeneous multiple myeloma
Larrayoz, Marta, Garcia-Barchino, Maria J, Celay, Jon, Etxebeste, Amaia, Jimenez, Maddalen, Perez, Cristina, Ordoñez, Raquel, Cobaleda, Cesar, Botta, Cirino, Fresquet, Vicente, Roa, Sergio, Goicoechea, Ibai, Maia, Catarina, Lasaga, Miren, Chesi, Marta, Bergsagel, P Leif, Larrayoz, Maria J, Calasanz, Maria J, Campos-Sanchez, Elena, Martinez-Cano, Jorge, Panizo, Carlos, Rodriguez-Otero, Paula, Vicent, Silvestre, Roncador, Giovanna, Gonzalez, Patricia, Takahashi, Satoru, Katz, Samuel G, Walensky, Loren D, Ruppert, Shannon M, Lasater, Elisabeth A, Amann, Maria, Lozano, Teresa, Llopiz, Diana, Sarobe, Pablo, Lasarte, Juan J, Planell, Nuria, Gomez-Cabrero, David, Kudryashova, Olga, Kurilovich, Anna, Revuelta, Maria V, Cerchietti, Leandro, Agirre, Xabier, San Miguel, Jesus, Paiva, Bruno, Prosper, Felipe, Martinez-Climent, Jose A
Published in Nature medicine (01.03.2023)
Published in Nature medicine (01.03.2023)
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Journal Article
CD25-T reg -depleting antibodies preserving IL-2 signaling on effector T cells enhance effector activation and antitumor immunity
Solomon, Isabelle, Amann, Maria, Goubier, Anne, Arce Vargas, Frederick, Zervas, Dimitrios, Qing, Chen, Henry, Jake Y, Ghorani, Ehsan, Akarca, Ayse U, Marafioti, Teresa, Śledzińska, Anna, Werner Sunderland, Mariana, Franz Demane, Dafne, Clancy, Joanne Ruth, Georgiou, Andrew, Salimu, Josephine, Merchiers, Pascal, Brown, Mark Adrian, Flury, Reto, Eckmann, Jan, Murgia, Claudio, Sam, Johannes, Jacobsen, Bjoern, Marrer-Berger, Estelle, Boetsch, Christophe, Belli, Sara, Leibrock, Lea, Benz, Joerg, Koll, Hans, Sutmuller, Roger, Peggs, Karl S, Quezada, Sergio A
Published in Nature cancer (01.12.2020)
Published in Nature cancer (01.12.2020)
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Journal Article
Simultaneous targeting of PD-1 and IL-2Rβγ with radiation therapy to inhibit pancreatic cancer growth and metastasis
Piper, Miles, Hoen, Maureen, Darragh, Laurel B, Knitz, Michael, Nugyen, Diemmy, Gadwa, Jacob, Durini, Greta, Karakoc, Idil, Grier, Abby, Neupert, Brooke, Van Court, Benjamin, Abdelazeem, Khalid N M, Yu, Justin, Olimpo, Nicholas, Corbo, Sophia, Ross, Richard Blake, Pham, Tiffany, Joshi, Molishree, Kedl, Ross M, Saviola, Anthony, Amann, Maria, Umaña, Pablo, Codarri-Deak, Laura, Klein, Christian, D’Alessandro, Angelo, Karam, Sana D
Published in Cancer cell (27.04.2023)
Published in Cancer cell (27.04.2023)
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Journal Article
CEA/CD3 bispecific antibody MEDI-565/AMG 211 activation of T cells and subsequent killing of human tumors is independent of mutations commonly found in colorectal adenocarcinomas
Oberst, Michael D, Fuhrmann, Stacy, Mulgrew, Kathy, Amann, Maria, Cheng, Lily, Lutterbuese, Petra, Richman, Laura, Coats, Steve, Baeuerle, Patrick A, Hammond, Scott A
Published in mAbs (2014)
Published in mAbs (2014)
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Journal Article
Abstract 4553: The CD25 antibody RG6292 selectively depletes Tregs while preserving IL-2 signaling and CTL activity for tumor control
Amann, Maria, Schnetzler, Gabriel, Theresa, Kolben, Solomon, Isabelle, Boetsch, Christophe, Marrer-Berger, Estelle, Flury, Reto, Murgia, Claudio, Karanikas, Vaios, Sam, Johannes, Sutmuller, Roger, Eckmann, Jan, Koll, Hans, Belli, Sara, Vargas, Frederic Arce, Zervas, Dimitrios, Qing, Chen, Brown, Mark A., Salimu, Josephine, Goubier, Anne, Neumann, Sebastian, Peggs, Karl S., Quezada, Sergio A.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Abstract 3634: A novel tumor-targeted 4-1BB agonist and its combination with T-cell bispecific antibodies: an off-the-shelf cancer immunotherapy alternative to CAR T-cells
Claus, Christina, Ferrara, Claudia, Lang, Sabine, Albrecht, Rosmarie, Herter, Sylvia, Amann, Maria, Richards-Grau, Sandra, Sam, Johannes, Colombetti, Sara, Bacac, Marina, Klein, Christian, Umana, Pablo
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Abstract 6709: P329G-Engager: A novel universal antibody-based adaptor platform for cancer immunotherapy
Surowka, Marlena, Hutter-Karakoc, Idil, Darowski, Diana, Claus, Christina, Koller, Claudia Ferrara, Freimoser-Grundschober, Anne, Hofer, Thomas, Sobieniecki, Andrzej, Assisi, Denis, Leclair, Stephane, Moessner, Ekkehard, Umaña, Pablo, Amann, Maria, Klein, Christian
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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