L1-associated genomic regions are deleted in somatic cells of the healthy human brain
Erwin, Jennifer A, Paquola, Apuã C M, Singer, Tatjana, Gallina, Iryna, Novotny, Mark, Quayle, Carolina, Bedrosian, Tracy A, Alves, Francisco I A, Butcher, Cheyenne R, Herdy, Joseph R, Sarkar, Anindita, Lasken, Roger S, Muotri, Alysson R, Gage, Fred H
Published in Nature neuroscience (01.12.2016)
Published in Nature neuroscience (01.12.2016)
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Altered network and rescue of human neurons derived from individuals with early-onset genetic epilepsy
Negraes, Priscilla D., Trujillo, Cleber A., Yu, Nam-Kyung, Wu, Wei, Yao, Hang, Liang, Nicholas, Lautz, Jonathan D., Kwok, Ellius, McClatchy, Daniel, Diedrich, Jolene, de Bartolome, Salvador Martinez, Truong, Justin, Szeto, Ryan, Tran, Timothy, Herai, Roberto H., Smith, Stephen E. P., Haddad, Gabriel G., Yates, John R., Muotri, Alysson R.
Published in Molecular psychiatry (01.11.2021)
Published in Molecular psychiatry (01.11.2021)
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Journal Article
Differential L1 regulation in pluripotent stem cells of humans and apes
Marchetto, Maria C. N., Narvaiza, Iñigo, Denli, Ahmet M., Benner, Christopher, Lazzarini, Thomas A., Nathanson, Jason L., Paquola, Apuã C. M., Desai, Keval N., Herai, Roberto H., Weitzman, Matthew D., Yeo, Gene W., Muotri, Alysson R., Gage, Fred H.
Published in Nature (London) (29.11.2013)
Published in Nature (London) (29.11.2013)
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Journal Article
Autism-linked Cullin3 germline haploinsufficiency impacts cytoskeletal dynamics and cortical neurogenesis through RhoA signaling
Amar, Megha, Pramod, Akula Bala, Yu, Nam-Kyung, Herrera, Victor Munive, Qiu, Lily R., Moran-Losada, Patricia, Zhang, Pan, Trujillo, Cleber A., Ellegood, Jacob, Urresti, Jorge, Chau, Kevin, Diedrich, Jolene, Chen, Jiaye, Gutierrez, Jessica, Sebat, Jonathan, Ramanathan, Dhakshin, Lerch, Jason P., Yates, John R., Muotri, Alysson R., Iakoucheva, Lilia M.
Published in Molecular psychiatry (01.07.2021)
Published in Molecular psychiatry (01.07.2021)
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Journal Article
Pharmacological reversal of synaptic and network pathology in human MECP2‐KO neurons and cortical organoids
Trujillo, Cleber A, Adams, Jason W, Negraes, Priscilla D, Carromeu, Cassiano, Tejwani, Leon, Acab, Allan, Tsuda, Ben, Thomas, Charles A, Sodhi, Neha, Fichter, Katherine M, Romero, Sarah, Zanella, Fabian, Sejnowski, Terrence J, Ulrich, Henning, Muotri, Alysson R
Published in EMBO molecular medicine (11.01.2021)
Published in EMBO molecular medicine (11.01.2021)
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The contribution of GTF2I haploinsufficiency to Williams syndrome
Chailangkarn, Thanathom, Noree, Chalongrat, Muotri, Alysson R.
Published in Molecular and cellular probes (01.08.2018)
Published in Molecular and cellular probes (01.08.2018)
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Journal Article
Ataxia telangiectasia mutated (ATM) modulates long interspersed element-1 (L1) retrotransposition in human neural stem cells
Coufal, Nicole G, Garcia-Perez, Josè Luis, Peng, Grace E, Marchetto, Maria C. N, Muotri, Alysson R, Mu, Yangling, Carson, Christian T, Macia, Angela, Moran, John V, Gage, Fred H
Published in Proceedings of the National Academy of Sciences - PNAS (20.12.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (20.12.2011)
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Journal Article
Noncoding RNAs in the mammalian central nervous system
Cao, Xinwei, Yeo, Gene, Muotri, Alysson R, Kuwabara, Tomoko, Gage, Fred H
Published in Annual review of neuroscience (01.01.2006)
Published in Annual review of neuroscience (01.01.2006)
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Journal Article
Molecular neuroanatomy of anorexia nervosa
Howard, Derek, Negraes, Priscilla, Voineskos, Aristotle N., Kaplan, Allan S., Muotri, Alysson R., Duvvuri, Vikas, French, Leon
Published in Scientific reports (10.07.2020)
Published in Scientific reports (10.07.2020)
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Journal Article
Neuronal hyperexcitability and ion channel dysfunction in CDKL5-deficiency patient iPSC-derived cortical organoids
Wu, Wei, Yao, Hang, Negraes, Priscilla D., Wang, Juan, Trujillo, Cleber A., de Souza, Janaina S., Muotri, Alysson R., Haddad, Gabriel G.
Published in Neurobiology of disease (01.11.2022)
Published in Neurobiology of disease (01.11.2022)
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Journal Article
Effects of acute low-moderate dose ionizing radiation to human brain organoids
Oyefeso, Foluwasomi A, Goldberg, Gabriela, Opoku, Nana Yaa P S, Vazquez, Marcelo, Bertucci, Antonella, Chen, Zhong, Wang, Charles, Muotri, Alysson R, Pecaut, Michael J
Published in PloS one (31.05.2023)
Published in PloS one (31.05.2023)
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Journal Article
Intact piRNA pathway prevents L1 mobilization in male meiosis
Newkirk, Simon J., Lee, Suman, Grandi, Fiorella C., Gaysinskaya, Valeriya, Rosser, James M., Vanden Berg, Nicole, Hogarth, Cathryn A., Marchetto, Maria C. N., Muotri, Alysson R., Griswold, Michael D., Ye, Ping, Bortvin, Alex, Gage, Fred H., Boeke, Jef D., An, Wenfeng
Published in Proceedings of the National Academy of Sciences - PNAS (11.07.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (11.07.2017)
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Journal Article
Environmental influence on L1 retrotransposons in the adult hippocampus
Muotri, Alysson R., Zhao, Chunmei, Marchetto, Maria C.N., Gage, Fred H.
Published in Hippocampus (01.10.2009)
Published in Hippocampus (01.10.2009)
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Journal Article
Species-specific maturation profiles of human, chimpanzee and bonobo neural cells
Marchetto, Maria C, Hrvoj-Mihic, Branka, Kerman, Bilal E, Yu, Diana X, Vadodaria, Krishna C, Linker, Sara B, Narvaiza, Iñigo, Santos, Renata, Denli, Ahmet M, Mendes, Ana Pd, Oefner, Ruth, Cook, Jonathan, McHenry, Lauren, Grasmick, Jaeson M, Heard, Kelly, Fredlender, Callie, Randolph-Moore, Lynne, Kshirsagar, Rijul, Xenitopoulos, Rea, Chou, Grace, Hah, Nasun, Muotri, Alysson R, Padmanabhan, Krishnan, Semendeferi, Katerina, Gage, Fred H
Published in eLife (07.02.2019)
Published in eLife (07.02.2019)
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Journal Article
Transcription Factor 4 loss-of-function is associated with deficits in progenitor proliferation and cortical neuron content
Papes, Fabio, Camargo, Antonio P., de Souza, Janaina S., Carvalho, Vinicius M. A., Szeto, Ryan A., LaMontagne, Erin, Teixeira, José R., Avansini, Simoni H., Sánchez-Sánchez, Sandra M., Nakahara, Thiago S., Santo, Carolina N., Wu, Wei, Yao, Hang, Araújo, Barbara M. P., Velho, Paulo E. N. F., Haddad, Gabriel G., Muotri, Alysson R.
Published in Nature communications (02.05.2022)
Published in Nature communications (02.05.2022)
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Journal Article
Towards a 21st-century roadmap for biomedical research and drug discovery: consensus report and recommendations
Langley, Gillian R., Adcock, Ian M., Busquet, François, Crofton, Kevin M., Csernok, Elena, Giese, Christoph, Heinonen, Tuula, Herrmann, Kathrin, Hofmann-Apitius, Martin, Landesmann, Brigitte, Marshall, Lindsay J., McIvor, Emily, Muotri, Alysson R., Noor, Fozia, Schutte, Katrin, Seidle, Troy, van de Stolpe, Anja, Van Esch, Hilde, Willett, Catherine, Woszczek, Grzegorz
Published in Drug discovery today (01.02.2017)
Published in Drug discovery today (01.02.2017)
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MeCP2 controls neural stem cell fate specification through miR-199a-mediated inhibition of BMP-Smad signaling
Nakashima, Hideyuki, Tsujimura, Keita, Irie, Koichiro, Imamura, Takuya, Trujillo, Cleber A., Ishizu, Masataka, Uesaka, Masahiro, Pan, Miao, Noguchi, Hirofumi, Okada, Kanako, Aoyagi, Kei, Andoh-Noda, Tomoko, Okano, Hideyuki, Muotri, Alysson R., Nakashima, Kinichi
Published in Cell reports (Cambridge) (18.05.2021)
Published in Cell reports (Cambridge) (18.05.2021)
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Journal Article
Metabolic and Organelle Morphology Defects in Mice and Human Patients Define Spinocerebellar Ataxia Type 7 as a Mitochondrial Disease
Ward, Jacqueline M., Stoyas, Colleen A., Switonski, Pawel M., Ichou, Farid, Fan, Weiwei, Collins, Brett, Wall, Christopher E., Adanyeguh, Isaac, Niu, Chenchen, Sopher, Bryce L., Kinoshita, Chizuru, Morrison, Richard S., Durr, Alexandra, Muotri, Alysson R., Evans, Ronald M., Mochel, Fanny, La Spada, Albert R.
Published in Cell reports (Cambridge) (29.01.2019)
Published in Cell reports (Cambridge) (29.01.2019)
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Journal Article
Multipotent Stem Cells from Umbilical Cord: Cord Is Richer than Blood
Secco, Mariane, Zucconi, Eder, Vieira, Natassia M., Fogaça, Luciana L.Q., Cerqueira, Antonia, Carvalho, Maria Denise F., Jazedje, Tatiana, Okamoto, Oswaldo K., Muotri, Alysson R., Zatz, Mayana
Published in Stem cells (Dayton, Ohio) (01.01.2008)
Published in Stem cells (Dayton, Ohio) (01.01.2008)
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