No synergistic effect of subtherapeutic doses of donepezil and EVP-6124 in healthy elderly subjects in a scopolamine challenge model
Baakman, Anne Catrien, Alvarez-Jimenez, Ricardo, Loewen, Gordon, de Kam, Marieke L., Broekhuizen, Karen, Hilt, Dana C., Groeneveld, Geert Jan
Published in Alzheimer's & dementia : translational research & clinical interventions (2019)
Published in Alzheimer's & dementia : translational research & clinical interventions (2019)
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Post-burn hypertrophic scars are characterized by high levels of IL-1β mRNA and protein and TNF-α type I receptors
Salgado, Rosa M, Alcántara, Luz, Mendoza-Rodríguez, C. Adriana, Cerbón, Marco, Hidalgo-González, Christian, Mercadillo, Patricia, Moreno, Luis M, Álvarez-Jiménez, Ricardo, Krötzsch, Edgar
Published in Burns (01.08.2012)
Published in Burns (01.08.2012)
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EEG machine learning for accurate detection of cholinergic intervention and Alzheimer's disease
Simpraga, Sonja, Alvarez-Jimenez, Ricardo, Mansvelder, Huibert D, van Gerven, Joop M A, Groeneveld, Geert Jan, Poil, Simon-Shlomo, Linkenkaer-Hansen, Klaus
Published in Scientific reports (18.07.2017)
Published in Scientific reports (18.07.2017)
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Model‐based exposure‐response analysis to quantify age related differences in the response to scopolamine in healthy subjects
Alvarez‐Jimenez, Ricardo, Groeneveld, Geert Jan, Gerven, Joop M. A., Goulooze, Sebastiaan C., Baakman, Anne Catrien, Hay, Justin L., Stevens, Jasper
Published in British journal of clinical pharmacology (01.10.2016)
Published in British journal of clinical pharmacology (01.10.2016)
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Journal Article
Reversal of mecamylamine‐induced effects in healthy subjects by nicotine receptor agonists: Cognitive and (electro) physiological responses
Alvarez‐Jimenez, Ricardo, Hart, Ellen P., Prins, Samantha, Kam, Marieke, Gerven, Joop M.A., Cohen, Adam F., Groeneveld, Geert Jan
Published in British journal of clinical pharmacology (01.05.2018)
Published in British journal of clinical pharmacology (01.05.2018)
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Journal Article
An anti‐nicotinic cognitive challenge model using mecamylamine in comparison with the anti‐muscarinic cognitive challenge using scopolamine
Baakman, Anne Catrien, Alvarez‐Jimenez, Ricardo, Rissmann, Robert, Klaassen, Erica S., Stevens, Jasper, Goulooze, Sebastiaan C., Burger, Jeroen C. G., Swart, Eleonora L., Gerven, Joop M. A., Groeneveld, Geert Jan
Published in British journal of clinical pharmacology (01.08.2017)
Published in British journal of clinical pharmacology (01.08.2017)
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Journal Article
Dexmedetomidine Clearance Decreases with Increasing Drug Exposure: Implications for Current Dosing Regimens and Target-controlled Infusion Models Assuming Linear Pharmacokinetics
Alvarez-Jimenez, Ricardo, Weerink, Maud A S, Hannivoort, Laura N, Su, Hong, Struys, Michel M R F, Loer, Stephan A, Colin, Pieter J
Published in Anesthesiology (Philadelphia) (01.02.2022)
Published in Anesthesiology (Philadelphia) (01.02.2022)
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Journal Article
Pharmacotherapy in pediatric epilepsy: from trial and error to rational drug and dose selection - a long way to go
van Dijkman, Sven C., Alvarez-Jimenez, Ricardo, Danhof, Meindert, Della Pasqua, Oscar
Published in Expert opinion on drug metabolism & toxicology (02.10.2016)
Published in Expert opinion on drug metabolism & toxicology (02.10.2016)
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Journal Article
A Computerized Test Battery to Study Pharmacodynamic Effects on the Central Nervous System of Cholinergic Drugs in Early Phase Drug Development
Hart, Ellen P., Alvarez-Jimenez, Ricardo, Davidse, Esther, Doll, Robert Jan, Cohen, Adam F., Van Gerven, Joop M.A., Groeneveld, Geert Jan
Published in Journal of visualized experiments (11.02.2019)
Published in Journal of visualized experiments (11.02.2019)
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Journal Article
Pharmacokinetics and pharmacodynamics of oral mecamylamine - development of a nicotinic acetylcholine receptor antagonist cognitive challenge test using modelling and simulation
Alvarez-Jimenez, Ricardo, Baakman, Anne Catrien, Stevens, Jasper, Goulooze, Sebastiaan C, Hart, Ellen P, Rissmann, Robert, van Gerven, Joop Ma, Groeneveld, Geert Jan
Published in Journal of psychopharmacology (Oxford) (01.02.2017)
Published in Journal of psychopharmacology (Oxford) (01.02.2017)
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Journal Article
A Computerized Test Battery to Study Pharmacodynamic Effects on the Central Nervous System of Cholinergic Drugs in Early Phase Drug Development
Hart, Ellen P, Alvarez-Jimenez, Ricardo, Davidse, Esther, Doll, Robert Jan, Cohen, Adam F, Van Gerven, Joop M A, Groeneveld, Geert Jan
Published in Journal of visualized experiments (11.02.2019)
Published in Journal of visualized experiments (11.02.2019)
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Journal Article
Heparina en quemaduras de segundo grado profundo en un modelo murino
Sigler, Luis, Krotzsch, Edgar, Bretón-Mora, Fernando, Padilla, Luis, DiSilvio, Mauricio, Álvarez-Jiménez, Ricardo
Published in Cirujano general : órgano oficial científico de la Asociación Mexicana de Cirugiía General (01.06.2011)
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Published in Cirujano general : órgano oficial científico de la Asociación Mexicana de Cirugiía General (01.06.2011)
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