NLRP3 inflammasome activation downstream of cytoplasmic LPS recognition by both caspase‐4 and caspase‐5
Baker, Paul J., Boucher, Dave, Bierschenk, Damien, Tebartz, Christina, Whitney, Paul G., D'Silva, Damian B., Tanzer, Maria C., Monteleone, Mercedes, Robertson, Avril A. B., Cooper, Matthew A., Alvarez‐Diaz, Silvia, Herold, Marco J., Bedoui, Sammy, Schroder, Kate, Masters, Seth L.
Published in European journal of immunology (01.10.2015)
Published in European journal of immunology (01.10.2015)
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The effects of 1,25-dihydroxyvitamin D3 on colon cancer cells depend on RhoA-ROCK-p38MAPK-MSK signaling
ORDONEZ-MORAN, Paloma, ALVAREZ-DIAZ, Silvia, VALLE, Noelia, LARRIBA, María Jesús, BONILLA, Félix, MUNOZ, Alberto
Published in Journal of steroid biochemistry and molecular biology (01.07.2010)
Published in Journal of steroid biochemistry and molecular biology (01.07.2010)
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Conference Proceeding
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The Pseudokinase MLKL and the Kinase RIPK3 Have Distinct Roles in Autoimmune Disease Caused by Loss of Death-Receptor-Induced Apoptosis
Alvarez-Diaz, Silvia, Dillon, Christopher P., Lalaoui, Najoua, Tanzer, Maria C., Rodriguez, Diego A., Lin, Ann, Lebois, Marion, Hakem, Razq, Josefsson, Emma C., O’Reilly, Lorraine A., Silke, John, Alexander, Warren S., Green, Douglas R., Strasser, Andreas
Published in Immunity (Cambridge, Mass.) (20.09.2016)
Published in Immunity (Cambridge, Mass.) (20.09.2016)
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Journal Article
Aberrant miR-182 expression promotes melanoma metastasis by repressing FOXO3 and microphthalmia-associated transcription factor
Segura, Miguel F, Hanniford, Douglas, Menendez, Silvia, Reavie, Linsey, Zou, Xuanyi, Alvarez-Diaz, Silvia, Zakrzewski, Jan, Blochin, Elen, Rose, Amy, Bogunovic, Dusan, Polsky, David, Wei, Jianjun, Lee, Peng, Belitskaya-Levy, Ilana, Bhardwaj, Nina, Osman, Iman, Hernando, Eva
Published in Proceedings of the National Academy of Sciences - PNAS (10.02.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (10.02.2009)
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MicroRNA-22 is induced by vitamin D and contributes to its antiproliferative, antimigratory and gene regulatory effects in colon cancer cells
ALVAREZ-DIAZ, Silvia, VALLE, Noelia, FERRER-MAYORGA, Gemma, LOMBARDIA, Luis, HERRERA, Mercedes, DOMINGUEZ, Orlando, SEGURA, Miguel F, BONILLA, Félix, HERNANDO, Eva, MUNOZ, Alberto
Published in Human molecular genetics (15.05.2012)
Published in Human molecular genetics (15.05.2012)
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Linear ubiquitin chain assembly complex coordinates late thymic T-cell differentiation and regulatory T-cell homeostasis
Teh, Charis E., Lalaoui, Najoua, Jain, Reema, Policheni, Antonia N., Heinlein, Melanie, Alvarez-Diaz, Silvia, Sheridan, Julie M., Rieser, Eva, Deuser, Stefanie, Darding, Maurice, Koay, Hui-Fern, Hu, Yifang, Kupresanin, Fiona, O’Reilly, Lorraine A., Godfrey, Dale I., Smyth, Gordon K., Bouillet, Philippe, Strasser, Andreas, Walczak, Henning, Silke, John, Gray, Daniel H. D.
Published in Nature communications (18.11.2016)
Published in Nature communications (18.11.2016)
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Journal Article
Cystatin D is a candidate tumor suppressor gene induced by vitamin D in human colon cancer cells
Alvarez-Díaz, Silvia, Valle, Noelia, García, José Miguel, Peña, Cristina, Freije, José M P, Quesada, Víctor, Astudillo, Aurora, Bonilla, Félix, López-Otín, Carlos, Muñoz, Alberto
Published in The Journal of clinical investigation (01.08.2009)
Published in The Journal of clinical investigation (01.08.2009)
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Journal Article
Vitamin D: Proteases, protease inhibitors and cancer
Álvarez-Díaz, Silvia, Larriba, María Jesús, López-Otín, Carlos, Muñoz, Alberto
Published in Cell cycle (Georgetown, Tex.) (01.01.2010)
Published in Cell cycle (Georgetown, Tex.) (01.01.2010)
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Journal Article
Cystatin D Locates in the Nucleus at Sites of Active Transcription and Modulates Gene and Protein Expression
Ferrer-Mayorga, Gemma, Alvarez-Díaz, Silvia, Valle, Noelia, De Las Rivas, Javier, Mendes, Marta, Barderas, Rodrigo, Canals, Francesc, Tapia, Olga, Casal, J. Ignacio, Lafarga, Miguel, Muñoz, Alberto
Published in The Journal of biological chemistry (30.10.2015)
Published in The Journal of biological chemistry (30.10.2015)
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Journal Article
The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism
Murphy, James M., Czabotar, Peter E., Hildebrand, Joanne M., Lucet, Isabelle S., Zhang, Jian-Guo, Alvarez-Diaz, Silvia, Lewis, Rowena, Lalaoui, Najoua, Metcalf, Donald, Webb, Andrew I., Young, Samuel N., Varghese, Leila N., Tannahill, Gillian M., Hatchell, Esme C., Majewski, Ian J., Okamoto, Toru, Dobson, Renwick C.J., Hilton, Douglas J., Babon, Jeffrey J., Nicola, Nicos A., Strasser, Andreas, Silke, John, Alexander, Warren S.
Published in Immunity (Cambridge, Mass.) (19.09.2013)
Published in Immunity (Cambridge, Mass.) (19.09.2013)
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Journal Article
Necroptosis is dispensable for the development of inflammation-associated or sporadic colon cancer in mice
Alvarez-Diaz, Silvia, Preaudet, Adele, Samson, Andre L., Nguyen, Paul M., Fung, Ka Yee, Garnham, Alexandra L., Alexander, Warren S., Strasser, Andreas, Ernst, Matthias, Putoczki, Tracy L., Murphy, James M.
Published in Cell death and differentiation (01.05.2021)
Published in Cell death and differentiation (01.05.2021)
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Synthesis and Biological Evaluation of 1 alpha,25-Dihydroxyvitamin D-3 Analogues with a Long Side Chain at C12 and Short C17 Side Chains
Carballa, Diego M., Seoane, Samuel, Zacconi, Flavia, Perez, Xenxo, Rumbo, Antonio, Alvarez-Diaz, Silvia, Jesus Larriba, Maria, Perez-Fernandez, Roman, Munoz, Alberto, Maestro, Miguel, Mourino, Antonio, Torneiro, Mercedes
Published in Journal of medicinal chemistry (25.10.2012)
Published in Journal of medicinal chemistry (25.10.2012)
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Journal Article
Loss of RIPK3 does not impact MYC-driven lymphomagenesis or chemotherapeutic drug-induced killing of malignant lymphoma cells
Thijssen, Rachel, Alvarez-Diaz, Silvia, Grace, Clea, Gao, Ming-yuan, Segal, David H., Xu, Zhen, Strasser, Andreas, Huang, David C. S.
Published in Cell death and differentiation (01.08.2020)
Published in Cell death and differentiation (01.08.2020)
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Journal Article
The inhibition of Wnt/β-catenin signalling by 1α,25-dihydroxyvitamin D3 is abrogated by Snail1 in human colon cancer cells
Larriba, María Jesús, Valle, Noelia, Pálmer, Héctor G, Ordóñez-Morán, Paloma, Álvarez-Díaz, Silvia, Becker, Karl-Friedrich, Gamallo, Carlos, de Herreros, Antonio García, González-Sancho, José Manuel, Muñoz, Alberto
Published in Endocrine-related cancer (01.03.2007)
Published in Endocrine-related cancer (01.03.2007)
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LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis
Peltzer, Nieves, Darding, Maurice, Montinaro, Antonella, Draber, Peter, Draberova, Helena, Kupka, Sebastian, Rieser, Eva, Fisher, Amanda, Hutchinson, Ciaran, Taraborrelli, Lucia, Hartwig, Torsten, Lafont, Elodie, Haas, Tobias L., Shimizu, Yutaka, Böiers, Charlotta, Sarr, Aida, Rickard, James, Alvarez-Diaz, Silvia, Ashworth, Michael T., Beal, Allison, Enver, Tariq, Bertin, John, Kaiser, William, Strasser, Andreas, Silke, John, Bouillet, Philippe, Walczak, Henning
Published in Nature (London) (01.05.2018)
Published in Nature (London) (01.05.2018)
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Journal Article
Synthesis and Biological Evaluation of 1α,25-Dihydroxyvitamin D3 Analogues with a Long Side Chain at C12 and Short C17 Side Chains
Carballa, Diego M, Seoane, Samuel, Zacconi, Flavia, Pérez, Xenxo, Rumbo, Antonio, Alvarez-Díaz, Silvia, Larriba, María Jesús, Pérez-Fernández, Román, Muñoz, Alberto, Maestro, Miguel, Mouriño, Antonio, Torneiro, Mercedes
Published in Journal of medicinal chemistry (25.10.2012)
Published in Journal of medicinal chemistry (25.10.2012)
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Is SIRT2 required for necroptosis?
Newton, Kim, Hildebrand, Joanne M., Shen, Zhirong, Rodriguez, Diego, Alvarez-Diaz, Silvia, Petersen, Sean, Shah, Saumil, Dugger, Debra L., Huang, Chunzi, Auwerx, Johan, Vandenabeele, Peter, Green, Douglas R., Ashkenazi, Avi, Dixit, Vishva M., Kaiser, William J., Strasser, Andreas, Degterev, Alexei, Silke, John
Published in Nature (London) (27.02.2014)
Published in Nature (London) (27.02.2014)
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The effects of 1,25-dihydroxyvitamin D sub(3) on colon cancer cells depend on RhoA-ROCK-p38MAPK-MSK signaling
Ordonez-Moran, Paloma, Alvarez-Diaz, Silvia, Valle, Noelia, Larriba, Maria Jesus, Bonilla, Felix, Munoz, Alberto
Published in The Journal of steroid biochemistry and molecular biology (01.07.2010)
Published in The Journal of steroid biochemistry and molecular biology (01.07.2010)
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Journal Article
The effects of 1,25-dihydroxyvitamin D 3 on colon cancer cells depend on RhoA-ROCK-p38MAPK-MSK signaling
Ordóñez-Morán, Paloma, Álvarez-Díaz, Silvia, Valle, Noelia, Larriba, María Jesús, Bonilla, Félix, Muñoz, Alberto
Published in The Journal of steroid biochemistry and molecular biology (01.07.2010)
Published in The Journal of steroid biochemistry and molecular biology (01.07.2010)
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Journal Article
The inhibition of Wnt/beta-catenin signalling by 1alpha,25-dihydroxyvitamin D3 is abrogated by Snail1 in human colon cancer cells
Larriba, María Jesús, Valle, Noelia, Pálmer, Héctor G, Ordóñez-Morán, Paloma, Alvarez-Díaz, Silvia, Becker, Karl-Friedrich, Gamallo, Carlos, de Herreros, Antonio García, González-Sancho, José Manuel, Muñoz, Alberto
Published in Endocrine-related cancer (01.03.2007)
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Published in Endocrine-related cancer (01.03.2007)
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