Water Bridges Play a Key Role in Affinity and Selectivity for Malarial Protease Falcipain‑2
Hernández González, Jorge Enrique, Hernández Alvarez, Lilian, Leite, Vitor B. P, Pascutti, Pedro Geraldo
Published in Journal of chemical information and modeling (23.11.2020)
Published in Journal of chemical information and modeling (23.11.2020)
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Journal Article
Three Decades of Targeting Falcipains to Develop Antiplasmodial Agents: What have we Learned and What can be Done Next?
González, Jorge Enrique Hernández, Salas-Sarduy, Emir, Alvarez, Lilian Hernández, Valiente, Pedro Alberto, Arni, Raghuvir Krishnaswamy, Pascutti, Pedro Geraldo
Published in Current medicinal chemistry (01.01.2024)
Published in Current medicinal chemistry (01.01.2024)
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Journal Article
Prediction of Noncompetitive Inhibitor Binding Mode Reveals Promising Site for Allosteric Modulation of Falcipain‑2
Hernández González, Jorge Enrique, Hernández Alvarez, Lilian, Pascutti, Pedro Geraldo, Leite, Vitor B. P
Published in The journal of physical chemistry. B (29.08.2019)
Published in The journal of physical chemistry. B (29.08.2019)
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Journal Article
Computational study on the allosteric mechanism of Leishmania major IF4E-1 by 4E-interacting protein-1: Unravelling the determinants of m7GTP cap recognition
Hernández-Alvarez, Lilian, Oliveira Jr, Antonio B, Hernández-González, Jorge Enrique, Chahine, Jorge, Pascutti, Pedro Geraldo, de Araujo, Alexandre Suman, de Souza, Fátima Pereira
Published in Computational and structural biotechnology journal (01.01.2021)
Published in Computational and structural biotechnology journal (01.01.2021)
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Journal Article
Insights into the Interactions of Fasciola hepatica Cathepsin L3 with a Substrate and Potential Novel Inhibitors through In Silico Approaches
Hernández Alvarez, Lilian, Naranjo Feliciano, Dany, Hernández González, Jorge Enrique, Soares, R O, Soares, Rosemberg de Oliveira, Barreto Gomes, Diego Enry, Pascutti, Pedro Geraldo
Published in PLoS neglected tropical diseases (01.05.2015)
Published in PLoS neglected tropical diseases (01.05.2015)
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Journal Article
Predicting binding modes of reversible peptide‐based inhibitors of falcipain‐2 consistent with structure–activity relationships
Hernández González, Jorge Enrique, Hernández Alvarez, Lilian, Pascutti, Pedro Geraldo, Valiente, Pedro A.
Published in Proteins, structure, function, and bioinformatics (01.09.2017)
Published in Proteins, structure, function, and bioinformatics (01.09.2017)
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Journal Article
In silico identification of noncompetitive inhibitors targeting an uncharacterized allosteric site of falcipain-2
Hernández González, Jorge Enrique, Salas-Sarduy, Emir, Hernández Alvarez, Lilian, Barreto Gomes, Diego Enry, Pascutti, Pedro Geraldo, Oostenbrink, Chris, Leite, Vitor B. P.
Published in Journal of computer-aided molecular design (01.10.2021)
Published in Journal of computer-aided molecular design (01.10.2021)
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Journal Article
Proteomic Study to Survey the CIGB-552 Antitumor Effect
Musacchio-Lasa, Alexis, Padrón, Gabriel, González López, Luis J., Besada, Vladimir, Vallespí, Maribel G., Sánchez-Puente, Aniel, García, Dayana, Oliva Argüelles, Brizaida, Flores, Lisandra, Hernández-Álvarez, Lilian, Ramos, Yassel, Gil, Jeovanis, Rodríguez-Ulloa, Arielis, Fernández-de-Cossio, Jorge
Published in BioMed research international (01.01.2015)
Published in BioMed research international (01.01.2015)
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Journal Article
Deciphering the emergence, genetic diversity and evolution of classical swine fever virus
Rios, Liliam, Coronado, Liani, Naranjo-Feliciano, Dany, Martínez-Pérez, Orlando, Perera, Carmen L, Hernandez-Alvarez, Lilian, Díaz de Arce, Heidy, Núñez, José I, Ganges, Llilianne, Pérez, Lester J
Published in Scientific reports (20.12.2017)
Published in Scientific reports (20.12.2017)
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Journal Article
Predicting binding modes of reversible peptide-based inhibitors of falcipain-2 consistent with structure-activity relationships: Binding Modes of Peptide-Based Inhibitors to FP-2
Hernández González, Jorge Enrique, Hernández Alvarez, Lilian, Pascutti, Pedro Geraldo, Valiente, Pedro A.
Published in Proteins, structure, function, and bioinformatics (01.09.2017)
Published in Proteins, structure, function, and bioinformatics (01.09.2017)
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Journal Article
Computational study on the allosteric mechanism of Leishmania major IF4E-1 by 4E-interacting protein-1: Unravelling the determinants of m 7 GTP cap recognition
Hernández-Alvarez, Lilian, Oliveira, Jr, Antonio B, Hernández-González, Jorge Enrique, Chahine, Jorge, Pascutti, Pedro Geraldo, de Araujo, Alexandre Suman, de Souza, Fátima Pereira
Published in Computational and structural biotechnology journal (2021)
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Published in Computational and structural biotechnology journal (2021)
Journal Article
Insights into the Interactions of Fasciola hepatica Cathepsin L3 with a Substrate and Potential Novel Inhibitors through In Silico Approaches: e0003759
Alvarez, Lilian Hernández, Feliciano, Dany Naranjo, González, Jorge EnriqueHernández, Soares, Rosemberg deOliveira, Gomes, Diego EnryBarreto, Pascutti, Pedro Geraldo
Published in PLoS neglected tropical diseases (01.05.2015)
Published in PLoS neglected tropical diseases (01.05.2015)
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Journal Article
Intramolecular Interactions Enhance the Potency of Gallinamide A Analogues against Trypanosoma cruzi
Barbosa Da Silva, Elany, Sharma, Vandna, Hernandez-Alvarez, Lilian, Tang, Arthur H, Stoye, Alexander, O’Donoghue, Anthony J, Gerwick, William H, Payne, Richard J, McKerrow, James H, Podust, Larissa M
Published in Journal of medicinal chemistry (10.03.2022)
Published in Journal of medicinal chemistry (10.03.2022)
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Journal Article
La inteligencia emocional en la formación de profesionales de Trabajo Social en salud
Cañizares Espinosa, Yamiley, Bernal, Leticia, Hernández Álvarez, Lilian Blaza, Espinosa Navarro, Serguey, Rojas Gómez, María Caridad de, Ramos Cuellar, Saily
Published in Edumecentro (2019)
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Published in Edumecentro (2019)
Journal Article
Intramolecular interactions enhance the potency of gallinamide A analogs against Trypanosoma cruzi
Elany Barbosa Da Silva, Sharma, Vandna, Hernandez-Alvarez, Lilian, Tang, Arthur H, Stoye, Alexander, O'donoghue, Anthony J, Gerwick, William H, Payne, Richard J, Mckerrow, James H, Podust, Larissa M
Published in bioRxiv (23.12.2021)
Published in bioRxiv (23.12.2021)
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