Understanding a high-risk acute myeloid leukemia by analyzing the interactome of its major driver mutation
Chiriches, Claudia, Nicolaisen, Nathalie, Wieske, Maria, Elhaddad, Heba, Mehmetbeyoglu, Ecmel, Alvares, Caroline, Becher, Dörte, Hole, Paul, Ottmann, Oliver Gerhard, Ruthardt, Martin
Published in PLoS genetics (26.10.2022)
Published in PLoS genetics (26.10.2022)
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Combination of a mitogen‐activated protein kinase inhibitor with the tyrosine kinase inhibitor pacritinib combats cell adhesion‐based residual disease and prevents re‐expansion of FLT3‐ITD acute myeloid leukaemia
Zabkiewicz, Joanna, Lazenby, Michelle, Edwards, Gareth, Bygrave, Ceri A., Omidvar, Nader, Zhuang, Lihui, Knapper, Steve, Guy, Carol, Hills, Robert K., Burnett, Alan K., Alvares, Caroline L.
Published in British journal of haematology (01.10.2020)
Published in British journal of haematology (01.10.2020)
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Inhibitors of the tyrosine kinases FMS-like tyrosine kinase-3 and WEE1 induce apoptosis and DNA damage synergistically in acute myeloid leukemia cells
Hieber, Christoph, Mustafa, Al-Hassan M., Neuroth, Sarah, Henninger, Sven, Wollscheid, Hans-Peter, Zabkiewicz, Joanna, Lazenby, Michelle, Alvares, Caroline, Mahboobi, Siavosh, Butter, Falk, Brenner, Walburgis, Bros, Matthias, Krämer, Oliver H.
Published in Biomedicine & pharmacotherapy (01.08.2024)
Published in Biomedicine & pharmacotherapy (01.08.2024)
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A phase 1b study of venetoclax and alvocidib in patients with relapsed/refractory acute myeloid leukemia
Jonas, Brian A, Hou, Jing-Zhou, Roboz, Gail J, Alvares, Caroline L, Jeyakumar, Deepa, Edwards, John R, Erba, Harry P, Kelly, Richard J, Röllig, Christoph, Fiedler, Walter, Brackman, Deanna, Siddani, Satya R, Chyla, Brenda, Hilger-Rolfe, Jacqueline, Watts, Justin M
Published in Hematological oncology (01.10.2023)
Published in Hematological oncology (01.10.2023)
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Characterization of milk production systems in the county of Alegrete, RS, Brazil, based on productive indexes
Caroline Alvares Silva, Leonardo Ereno Tadielo, Neliton Flores Kasper, Othon Dalla Colletta Altermann, Taiani Ourique Gayer, Rodrigo Holz Krolow, Ricardo Pedroso Oaigen, Deise Dalazen Castagnara
Published in Bioscience journal (01.01.2021)
Published in Bioscience journal (01.01.2021)
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The role of second autografts in the management of myeloma at first relapse
Alvares, CL, Davies, FE, Horton, C, Patel, G, Powles, R, Morgan, GJ
Published in Haematologica (Roma) (01.01.2006)
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Published in Haematologica (Roma) (01.01.2006)
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Tyrosine kinase inhibitor insensitivity of non‐cycling CD34+ human acute myeloid leukaemia cells with FMS‐like tyrosine kinase 3 mutations
Alvares, Caroline L., Schenk, Tino, Hulkki, Sanna, Min, Toon, Vijayaraghavan, Gowri, Yeung, Jenny, Gonzalez, David, So, Chi W. E., Greaves, Mel, Titley, Ian, Bartolovic, Kerol, Morgan, Gareth
Published in British journal of haematology (01.08.2011)
Published in British journal of haematology (01.08.2011)
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The combination of cyclophosphomide, thalidomide and dexamethasone is an effective alternative to cyclophosphamide - vincristine - doxorubicin - methylprednisolone as induction chemotherapy prior to autologous transplantation for multiple myeloma: a case-matched analysis
Wu, Ping, Davies, Faith E., Horton, Clive, Jenner, Matthew W., Krishnan, Biju, Alvares, Caroline L., Saso, Radovan, Mccormack, Rita, Dines, Sharon, Treleaven, Jennifer G., Potter, Michael N., Ethell, Mark E., Morgan, Gareth J
Published in Leukemia & lymphoma (01.11.2006)
Published in Leukemia & lymphoma (01.11.2006)
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Long‐term outcomes of previously untreated myeloma patients: responses to induction chemotherapy and high‐dose melphalan incorporated within a risk stratification model can help to direct the use of novel treatments
Alvares, Caroline L., Davies, Faith E., Horton, Clive, Patel, Gita, Powles, Ray, Sirohi, Bhawna, Zuha, Roslin, Gatt, Alex, Saso, Radovan, Treleaven, Jennifer G., Dearden, Claire E., Potter, Michael N., Ethell, Mark E., Morgan, Gareth J.
Published in British journal of haematology (01.06.2005)
Published in British journal of haematology (01.06.2005)
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Isolated Bone Marrow Involvement in Diffuse Large B Cell Lymphoma: A Report of Three Cases with Review of Morphological, Immunophenotypic and Cytogenetic Findings
Alvares, Caroline L, Matutes, Estella, Scully, Marie A, Swansbury, John, Min, Toon, Gruszka-Westwood, Alicja M, Atkinson, Shayne, Hilditch, Benjamin, Morilla, Ricardo, Wotherspoon, Andrew C, Catovsky, Daniel
Published in Leukemia & lymphoma (01.04.2004)
Published in Leukemia & lymphoma (01.04.2004)
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Adipogeneis in the Bone Marrow Microenvironment Confers a Proliferative Advantage in Residual Leukaemic Cell Populations in Acute Myeloid Leukaemia after Allogeneic Stem Cell Transplantation
May, Felicity, Alvares, Caroline, Ottmann, Oliver G., Zabkiewicz, Joanna
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy
Dolton, Garry, Rius, Cristina, Wall, Aaron, Szomolay, Barbara, Bianchi, Valentina, Galloway, Sarah A.E., Hasan, Md Samiul, Morin, Théo, Caillaud, Marine E., Thomas, Hannah L., Theaker, Sarah, Tan, Li Rong, Fuller, Anna, Topley, Katie, Legut, Mateusz, Attaf, Meriem, Hopkins, Jade R., Behiry, Enas, Zabkiewicz, Joanna, Alvares, Caroline, Lloyd, Angharad, Rogers, Amber, Henley, Peter, Fegan, Christopher, Ottmann, Oliver, Man, Stephen, Crowther, Michael D., Donia, Marco, Svane, Inge Marie, Cole, David K., Brown, Paul E., Rizkallah, Pierre, Sewell, Andrew K.
Published in Cell (03.08.2023)
Published in Cell (03.08.2023)
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Extracellular Microvesicle Cytokines Secreted from Bone Marrow Mesenchymal Cells Mediate Proliferative and Survival Advantage in Acute Myeloid Leukaemia
Lazenby, Michelle, Ottmann, Oliver G., Wilson, Keith, Alvares, Caroline, Zabkiewicz, Joanna
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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Bone Marrow Stromal Cells Mediate Adhesion Based Drug Resistance in Acute Myeloid Leukaemia through Reciprocal Feedback of the β-Catenin/CD44 Signalling Axis
Zhuang, Lihui, Darley, Richard, Ottmann, Oliver G., Zabkiewicz, Joanna, Alvares, Caroline
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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Successful molecular targeted treatment of AML in pregnancy with Azacitidine and Sorafenib with no adverse fetal outcomes
Mahdi, Ali J., Gosrani, Deepan, Chakraborty, Mallinath, Rees, Alexandra, Conner, Christine, Wilson, Keith, Rayment, Rachel, Alvares, Caroline
Published in British journal of haematology (01.02.2018)
Published in British journal of haematology (01.02.2018)
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Pacritinib Suppresses Leukemic Outgrowth from FLT3-ITD Positive Stroma-Adherent Primary AML Cells
Marrin, Ceri, Edwards, Gareth, Knapper, Steven, Burnett, Alan K., Zabkiewicz, Joanna, Alvares, Caroline
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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Characterization of milk production systems in the county of Alegrete, RS, Brazil, based on productive indexes
Caroline Alvares Silva, Leonardo Ereno Tadielo, Neliton Flores Kasper, Othon Dalla Colletta Altermann, Taiani Ourique Gayer, Rodrigo Holz Krolow, Ricardo Pedroso Oaigen, Deise Dalazen Castagnara
Published in Bioscience journal (01.06.2021)
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Published in Bioscience journal (01.06.2021)
Journal Article
Non-Cycling Cells From Acute Myeloid Leukemia Patients Harbor the FLT3-ITD Mutation and Are Insensitive to TKI258, a Potent FLT3-Directed Inhibitor, in Vitro
Alvares, Caroline L, Schenk, Tino, Hulkki, Sanna, Min, Toon, Vijayaraghavan, Gowri, Jenny, Yeung, Gonzalez, David, So, Eric, Greaves, Mel, Titley, Ian, Bartolovic, Kerol, Morgan, Gareth
Published in Blood (20.11.2009)
Published in Blood (20.11.2009)
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The Tyrosine Kinase Inhibitor TK258 Differentially Targets Proliferating Human Hematopoietic Progenitor Cells but Does Not Eliminate the Quiescent Fraction
Alvares, Caroline, Titley, Ian, Greaves, Mel, Potter, Michael, Kearney, Lyndal, Morgan, Gareth, Bartolovic, Kerol
Published in Blood (16.11.2007)
Published in Blood (16.11.2007)
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