Development of a precision medicine pipeline to identify personalized treatments for colorectal cancer
Altunel, Erdem, Roghani, Roham S, Chen, Kai-Yuan, Kim, So Young, McCall, Shannon, Ware, Kathryn E, Shen, Xiling, Somarelli, Jason A, Hsu, David S
Published in BMC cancer (24.06.2020)
Published in BMC cancer (24.06.2020)
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Journal Article
From the Clinic to the Bench and Back Again in One Dog Year: How a Cross-Species Pipeline to Identify New Treatments for Sarcoma Illuminates the Path Forward in Precision Medicine
Rao, Sneha R, Somarelli, Jason A, Altunel, Erdem, Selmic, Laura E, Byrum, Mark, Sheth, Maya U, Cheng, Serene, Ware, Kathryn E, Kim, So Young, Prinz, Joseph A, Devos, Nicolas, Corcoran, David L, Moseley, Arthur, Soderblom, Erik, Hsu, S David, Eward, William C
Published in Frontiers in oncology (11.02.2020)
Published in Frontiers in oncology (11.02.2020)
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Journal Article
Therapeutic potential of dual CDK12 and 13 inhibition in colorectal cancer
Altunel, Erdem, Zokaasadi, Mohammad, Somarelli, Jason A., McCall, Shannon J., Gultawatvichai, Patan, Whalen, Giles Francis, Pitarresi, Jason, Hsu, David S.
Published in Journal of clinical oncology (01.06.2023)
Published in Journal of clinical oncology (01.06.2023)
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Journal Article
A precision medicine strategy to identify the FGFR pathway as a novel target in colorectal cancer liver metastasis
Altunel, Erdem, Somarelli, Jason, Kim, So Young, Glover, Wayne, Rupprecht, Gabrielle, Hsu, Shiaowen David
Published in Journal of clinical oncology (01.02.2018)
Published in Journal of clinical oncology (01.02.2018)
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Journal Article
A precision medicine drug discovery pipeline to identify dual CDK2/9 inhibition as a novel treatment for colorectal cancer
Salman Roghani, Roham, Sanjari moghaddam, Ali, Rupprecht, Gabrielle, Altunel, Erdem, Kim, So Young, McCall, Shannon, Thomas, Beatrice, Ware, Katie, Somarelli, Jason, Hsu, David S.
Published in Journal of clinical oncology (20.05.2020)
Published in Journal of clinical oncology (20.05.2020)
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Journal Article
A Precision Medicine Drug Discovery Pipeline Identifies Combined CDK2 and 9 Inhibition as a Novel Therapeutic Strategy in Colorectal Cancer
Somarelli, Jason A, Roghani, Roham Salman, Moghaddam, Ali Sanjari, Thomas, Beatrice C, Rupprecht, Gabrielle, Ware, Kathryn E, Altunel, Erdem, Mantyh, John B, Kim, So Young, McCall, Shannon J, Shen, Xiling, Mantyh, Christopher R, Hsu, David S
Published in Molecular cancer therapeutics (01.12.2020)
Published in Molecular cancer therapeutics (01.12.2020)
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Journal Article
A Comparative Oncology Drug Discovery Pipeline to Identify and Validate New Treatments for Osteosarcoma
Somarelli, Jason A., Rupprecht, Gabrielle, Altunel, Erdem, Flamant, Etienne M., Rao, Sneha, Sivaraj, Dharshan, Lazarides, Alexander L., Hoskinson, Sarah M., Sheth, Maya U., Cheng, Serene, Kim, So Young, Ware, Kathryn E., Agarwal, Anika, Cullen, Mark M., Selmic, Laura E., Everitt, Jeffrey I., McCall, Shannon J., Eward, Cindy, Eward, William C., Hsu, David S.
Published in Cancers (11.11.2020)
Published in Cancers (11.11.2020)
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Journal Article
Abstract 1061: Exportin 1 (XPO1) inhibition alone or in combination as a novel therapeutic strategy in osteosarcoma
Graves, Laurie, Rupprecht, Gabrielle, Altunel, Erdem, Flamant, Etienne M., Rao, Sneha, Sivara, Dharshan, Lazarides, Alexander L., Hoskinson, Sarah M., Sheth, Maya U., Cheng, Serene, Kim, So Young, Ware, Kathryn E., Agarwal, Anika, Cullen, Mark M., Syal, Casey, Selmic, Laura E., Everitt, Jeffrey I., McCall, Shannon J., Eward, Cindy, Kashyap, Trinayan, Maloof, Marie, Walker, Christopher J., Landesman, Yosef, Wagner, Lars, Eward, William C., Hsu, David S., Somarelli, Jason A.
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Journal Article
Characterization of the Epidermal Growth Factor Receptor T790M Mutation in Colorectal Cancer
Altunel, Erdem, Aljamal, Abed Alhalim, Mantyh, John, Deak, Kristen, Glover, Wayne, McCall, Shannon J, Datto, Michael, Strickler, John, Hsu, David S
Published in JCO precision oncology (01.11.2018)
Published in JCO precision oncology (01.11.2018)
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Journal Article
Development of a precision medicine pipeline to identify personalized treatments for colorectal cancer
Erdem Altunel, Roghani, Roham S, Kai-Yuan, Chen, So Young Kim, McCall, Shannon, Ware, Kathryn E, Shen, Xiling, Somarelli, Jason A, Hsu, David S
Published in BMC Cancer (01.04.2020)
Published in BMC Cancer (01.04.2020)
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Web Resource
A cross-species drug discovery pipeline to identify and validate new treatments for osteosarcoma
Somarelli, Jason A, Rupprecht, Gabrielle, Erdem Altunel, Flamant, Etienne M, Rao, Sneha, Dharshan Sivaraj, Lazarides, Alexander L, Hoskinson, Sarah M, Sheth, Maya U, Cheng, Serene, So Young Kim, Ware, Kathryn E, Agarwal, Anika, Cullen, Mark M, Selmic, Laura E, Everitt, Jeffrey I, Mccall, Shannon J, Eward, Cindy, Eward, William C, Hsu, S David
Published in bioRxiv (21.10.2020)
Published in bioRxiv (21.10.2020)
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Paper
From the clinic to the bench and back again in one dog year: identifying new treatments for sarcoma using a cross-species personalized medicine pipeline
Rao, Sneha, Somarelli, Jason A, Erdem Altunel, Selmic, Laura E, Byrum, Mark, Sheth, Maya U, Cheng, Serene, Ware, Kathryn E, So Young Kim, Prinz, Joseph A, Devos, Nicolas, Corcoran, David L, Moseley, Arthur, Soderblom, Erik, Hsu, S David, Eward, William C
Published in bioRxiv (10.01.2019)
Published in bioRxiv (10.01.2019)
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Paper