Does Enhanced Structural Maturity of hiPSC-Cardiomyocytes Better for the Detection of Drug-Induced Cardiotoxicity?
Van de Sande, Dieter, Ghasemi, Mohammadreza, Watters, Taylor, Burton, Francis, Pham, Ly, Altrocchi, Cristina, Gallacher, David J, Lu, Huarong, Smith, Godfrey
Published in Biomolecules (Basel, Switzerland) (01.04.2023)
Published in Biomolecules (Basel, Switzerland) (01.04.2023)
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High-Throughput Screening Assay for Detecting Drug-Induced Changes in Synchronized Neuronal Oscillations and Potential Seizure Risk Based on Ca2+ Fluorescence Measurements in Human Induced Pluripotent Stem Cell (hiPSC)-Derived Neuronal 2D and 3D Cultures
Lu, Hua-Rong, Seo, Manabu, Kreir, Mohamed, Tanaka, Tetsuya, Yamoto, Rie, Altrocchi, Cristina, van Ammel, Karel, Tekle, Fetene, Pham, Ly, Yao, Xiang, Teisman, Ard, Gallacher, David J.
Published in Cells (Basel, Switzerland) (21.03.2023)
Published in Cells (Basel, Switzerland) (21.03.2023)
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INA Loss-of-Function by Compound Variants in SCN5A from a Large Founder Population with Excess Sudden Cardiac Death
Altrocchi, Cristina, Spätjens, Roel R.L., Sutanto, Henry, ter Bekke, Rachel M.A., Seyen, Sandrine, Heijman, Jordi, Moreno, Cristina, Volders, Paul G.A.
Published in Biophysical journal (02.02.2018)
Published in Biophysical journal (02.02.2018)
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Repolarization instability and arrhythmia by IKr block in single human-induced pluripotent stem cell-derived cardiomyocytes and 2D monolayers
Altrocchi, Cristina, de Korte, Tessa, Bernardi, Joyce, Spätjens, Roel L H M G, Braam, Stefan R, Heijman, Jordi, Zaza, Antonio, Volders, Paul G A
Published in Europace (London, England) (01.09.2020)
Published in Europace (London, England) (01.09.2020)
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Macrocyclic Carbon-Linked Pyrazoles As Novel Inhibitors of MCL‑1
Demin, Samuël, Peschiulli, Aldo, Velter, Adriana I., Vos, Ann, De Boeck, Benoît, Miller, Bradley, Rombouts, Frederik J. R., Reuillon, Tristan, Lento, William, Blanco, Maria Dominguez, Jouffroy, Matthieu, Steyvers, Helena, Bekkers, Mariette, Altrocchi, Cristina, Pietrak, Beth, Koo, Seong Joo, Szewczuk, Lawrence, Attar, Ricardo, Philippar, Ulrike
Published in ACS medicinal chemistry letters (13.07.2023)
Published in ACS medicinal chemistry letters (13.07.2023)
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High-Throughput Screening Assay for Detecting Drug-Induced Changes in Synchronized Neuronal Oscillations and Potential Seizure Risk Based on Ca 2+ Fluorescence Measurements in Human Induced Pluripotent Stem Cell (hiPSC)-Derived Neuronal 2D and 3D Cultures
Lu, Hua-Rong, Seo, Manabu, Kreir, Mohamed, Tanaka, Tetsuya, Yamoto, Rie, Altrocchi, Cristina, van Ammel, Karel, Tekle, Fetene, Pham, Ly, Yao, Xiang, Teisman, Ard, Gallacher, David J
Published in Cells (Basel, Switzerland) (21.03.2023)
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Published in Cells (Basel, Switzerland) (21.03.2023)
Journal Article
High-Throughput Screening Assay for Detecting Drug-Induced Changes in Synchronized Neuronal Oscillations and Potential Seizure Risk Based on Ca[sup.2+] Fluorescence Measurements in Human Induced Pluripotent Stem Cell -Derived Neuronal 2D and 3D Cultures
Lu, Hua-Rong, Seo, Manabu, Kreir, Mohamed, Tanaka, Tetsuya, Yamoto, Rie, Altrocchi, Cristina, van Ammel, Karel, Tekle, Fetene, Pham, Ly, Yao, Xiang, Teisman, Ard, Gallacher, David J
Published in Cells (Basel, Switzerland) (01.03.2023)
Published in Cells (Basel, Switzerland) (01.03.2023)
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Abstract 2133: In pursuit of MCL-1 inhibitors with improved therapeutic window for the treatment of hematological malignancies: Discovery of JNJ-4355
Rombouts, Frederik J., William, Lento, Velter, Ingrid, Vos, Ann, Peschiulli, Aldo, Tristan, Reuillon, Blanco, Maria Dominguez, Jouffroy, Matthieu, McQueen, Lisa, Steyvers, Helena, Bekkers, Mariette, Altrocchi, Cristina, Pietrak, Beth, Koo, Seong Joo, Szewczuk, Lawrence, Walker, David, Packman, Kathryn, Bueters, Ruud, Vinken, Petra, Johnson, Amy, Attar, Ricardo, Philippar, Ulrike
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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