Lipophilic nanocrystal prodrug-release defines the extended pharmacokinetic profiles of a year-long cabotegravir
Gautam, Nagsen, McMillan, JoEllyn M., Kumar, Devendra, Bade, Aditya N., Pan, Qiaoyu, Kulkarni, Tanmay A., Li, Wenkuan, Sillman, Brady, Smith, Nathan A., Shetty, Bhagya L. Dyavar, Szlachetka, Adam, Edagwa, Benson J., Gendelman, Howard E., Alnouti, Yazen
Published in Nature communications (08.06.2021)
Published in Nature communications (08.06.2021)
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Transformation of tenofovir into stable ProTide nanocrystals with long-acting pharmacokinetic profiles
Cobb, Denise A., Smith, Nathan, Deodhar, Suyash, Bade, Aditya N., Gautam, Nagsen, Shetty, Bhagya Laxmi Dyavar, McMillan, JoEllyn, Alnouti, Yazen, Cohen, Samuel M., Gendelman, Howard E., Edagwa, Benson
Published in Nature communications (16.09.2021)
Published in Nature communications (16.09.2021)
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Modulation of the intestinal bile acid/farnesoid X receptor/fibroblast growth factor 15 axis improves alcoholic liver disease in mice
Hartmann, Phillipp, Hochrath, Katrin, Horvath, Angela, Chen, Peng, Seebauer, Caroline T., Llorente, Cristina, Wang, Lirui, Alnouti, Yazen, Fouts, Derrick E., Stärkel, Peter, Loomba, Rohit, Coulter, Sally, Liddle, Christopher, Yu, Ruth T., Ling, Lei, Rossi, Stephen J., DePaoli, Alex M., Downes, Michael, Evans, Ronald M., Brenner, David A., Schnabl, Bernd
Published in Hepatology (Baltimore, Md.) (01.06.2018)
Published in Hepatology (Baltimore, Md.) (01.06.2018)
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Journal Article
A year-long extended release nanoformulated cabotegravir prodrug
Kulkarni, Tanmay A., Bade, Aditya N., Sillman, Brady, Shetty, Bhagya Laxmi Dyavar, Wojtkiewicz, Melinda S., Gautam, Nagsen, Hilaire, James R., Sravanam, Sruthi, Szlachetka, Adam, Lamberty, Benjamin G., Morsey, Brenda M., Fox, Howard S., Alnouti, Yazen, McMillan, JoEllyn M., Mosley, R. Lee, Meza, Jane, Domanico, Paul L., Yue, Tai-Yuen, Moore, Gary, Edagwa, Benson J., Gendelman, Howard E.
Published in Nature materials (01.08.2020)
Published in Nature materials (01.08.2020)
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Species differences in bile acids II. Bile acid metabolism
Thakare, Rhishikesh, Alamoudi, Jawaher Abdullah, Gautam, Nagsen, Rodrigues, A. David, Alnouti, Yazen
Published in Journal of applied toxicology (01.10.2018)
Published in Journal of applied toxicology (01.10.2018)
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Journal Article
Creation of a long-acting nanoformulated dolutegravir
Sillman, Brady, Bade, Aditya N., Dash, Prasanta K., Bhargavan, Biju, Kocher, Ted, Mathews, Saumi, Su, Hang, Kanmogne, Georgette D., Poluektova, Larisa Y., Gorantla, Santhi, McMillan, JoEllyn, Gautam, Nagsen, Alnouti, Yazen, Edagwa, Benson, Gendelman, Howard E.
Published in Nature communications (06.02.2018)
Published in Nature communications (06.02.2018)
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Quantitative-profiling of bile acids and their conjugates in mouse liver, bile, plasma, and urine using LC–MS/MS
Alnouti, Yazen, Csanaky, Iván L., Klaassen, Curtis D.
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.10.2008)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.10.2008)
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A combination of Omega-3 PUFAs and COX inhibitors: A novel strategy to manage obesity-linked dyslipidemia and adipose tissue inflammation
Saraswathi, Viswanathan, Heineman, Robert, Alnouti, Yazen, Shivaswamy, Vijay, Desouza, Cyrus V.
Published in Journal of diabetes and its complications (01.02.2020)
Published in Journal of diabetes and its complications (01.02.2020)
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Impaired synaptic development in a maternal immune activation mouse model of neurodevelopmental disorders
Coiro, Pierluca, Padmashri, Ragunathan, Suresh, Anand, Spartz, Elizabeth, Pendyala, Gurudutt, Chou, Shinnyi, Jung, Yoosun, Meays, Brittney, Roy, Shreya, Gautam, Nagsen, Alnouti, Yazen, Li, Ming, Dunaevsky, Anna
Published in Brain, behavior, and immunity (01.11.2015)
Published in Brain, behavior, and immunity (01.11.2015)
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Transformation of dolutegravir into an ultra-long-acting parenteral prodrug formulation
Deodhar, Suyash, Sillman, Brady, Bade, Aditya N., Avedissian, Sean N., Podany, Anthony T., McMillan, JoEllyn M., Gautam, Nagsen, Hanson, Brandon, Dyavar Shetty, Bhagya L., Szlachetka, Adam, Johnston, Morgan, Thurman, Michellie, Munt, Daniel J., Dash, Alekha K., Markovic, Milica, Dahan, Arik, Alnouti, Yazen, Yazdi, Alborz, Kevadiya, Bhavesh D., Byrareddy, Siddappa N., Cohen, Samuel M., Edagwa, Benson, Gendelman, Howard E.
Published in Nature communications (09.06.2022)
Published in Nature communications (09.06.2022)
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Journal Article
Development and characterization of a long-acting nanoformulated abacavir prodrug
Singh, Dhirender, McMillan, JoEllyn, Hilaire, James, Gautam, Nagsen, Palandri, Diana, Alnouti, Yazen, Gendelman, Howard E, Edagwa, Benson
Published in Nanomedicine (London, England) (01.08.2016)
Published in Nanomedicine (London, England) (01.08.2016)
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Crosstalk of hepatocyte nuclear factor 4a and glucocorticoid receptor in the regulation of lipid metabolism in mice fed a high-fat-high-sugar diet
Lu, Hong, Lei, Xiaohong, Winkler, Rebecca, John, Savio, Kumar, Devendra, Li, Wenkuan, Alnouti, Yazen
Published in Lipids in health and disease (25.05.2022)
Published in Lipids in health and disease (25.05.2022)
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Increased glycine-amidated hyocholic acid correlates to improved early weight loss after sleeve gastrectomy
Kindel, Tammy L., Krause, Crystal, Helm, Melissa C., McBride, Corrigan L., Oleynikov, Dmitry, Thakare, Rhishikesh, Alamoudi, Jawaher, Kothari, Vishal, Alnouti, Yazen, Kohli, Rohit
Published in Surgical endoscopy (01.02.2018)
Published in Surgical endoscopy (01.02.2018)
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Optimizing the preparation and stability of decorated antiretroviral drug nanocrystals
Zhou, Tian, Lin, Zhiyi, Puligujja, Pavan, Palandri, Diana, Hilaire, James, Araínga, Mariluz, Smith, Nathan, Gautam, Nagsen, McMillan, JoEllyn, Alnouti, Yazen, Liu, Xinming, Edagwa, Benson, Gendelman, Howard E
Published in Nanomedicine (London, England) (01.04.2018)
Published in Nanomedicine (London, England) (01.04.2018)
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