Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation
Rogers, Corey, Erkes, Dan A., Nardone, Alexandria, Aplin, Andrew E., Fernandes-Alnemri, Teresa, Alnemri, Emad S.
Published in Nature communications (11.04.2019)
Published in Nature communications (11.04.2019)
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Journal Article
The NLRP6 Inflammasome Recognizes Lipoteichoic Acid and Regulates Gram-Positive Pathogen Infection
Hara, Hideki, Seregin, Sergey S., Yang, Dahai, Fukase, Koichi, Chamaillard, Mathias, Alnemri, Emad S., Inohara, Naohiro, Chen, Grace Y., Núñez, Gabriel
Published in Cell (29.11.2018)
Published in Cell (29.11.2018)
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Journal Article
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
Fernandes-Alnemri, Teresa, Yu, Je-Wook, Datta, Pinaki, Wu, Jianghong, Alnemri, Emad S.
Published in Nature (26.03.2009)
Published in Nature (26.03.2009)
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Journal Article
Mutant BRAF and MEK Inhibitors Regulate the Tumor Immune Microenvironment via Pyroptosis
Erkes, Dan A, Cai, Weijia, Sanchez, Ileine M, Purwin, Timothy J, Rogers, Corey, Field, Conroy O, Berger, Adam C, Hartsough, Edward J, Rodeck, Ulrich, Alnemri, Emad S, Aplin, Andrew E
Published in Cancer discovery (01.02.2020)
Published in Cancer discovery (01.02.2020)
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Journal Article
The mitochondrial antiviral protein MAVS associates with NLRP3 and regulates its inflammasome activity
Park, Sangjun, Juliana, Christine, Hong, Sujeong, Datta, Pinaki, Hwang, Inhwa, Fernandes-Alnemri, Teresa, Yu, Je-Wook, Alnemri, Emad S
Published in The Journal of immunology (1950) (15.10.2013)
Published in The Journal of immunology (1950) (15.10.2013)
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Journal Article
Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3
Kang, Seokwon, Fernandes-Alnemri, Teresa, Rogers, Corey, Mayes, Lindsey, Wang, Ying, Dillon, Christopher, Roback, Linda, Kaiser, William, Oberst, Andrew, Sagara, Junji, Fitzgerald, Katherine A., Green, Douglas R., Zhang, Jianke, Mocarski, Edward S., Alnemri, Emad S.
Published in Nature communications (24.06.2015)
Published in Nature communications (24.06.2015)
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Journal Article
SUMO-mediated regulation of NLRP3 modulates inflammasome activity
Barry, Rachael, John, Sidonie Wicky, Liccardi, Gianmaria, Tenev, Tencho, Jaco, Isabel, Chen, Chih-Hong, Choi, Justin, Kasperkiewicz, Paulina, Fernandes-Alnemri, Teresa, Alnemri, Emad, Drag, Marcin, Chen, Yuan, Meier, Pascal
Published in Nature communications (01.08.2018)
Published in Nature communications (01.08.2018)
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Journal Article
Anti-inflammatory Compounds Parthenolide and Bay 11-7082 Are Direct Inhibitors of the Inflammasome
Juliana, Christine, Fernandes-Alnemri, Teresa, Wu, Jianghong, Datta, Pinaki, Solorzano, Leobaldo, Yu, Je-Wook, Meng, Rong, Quong, Andrew A., Latz, Eicke, Scott, Charles P., Alnemri, Emad S.
Published in The Journal of biological chemistry (26.03.2010)
Published in The Journal of biological chemistry (26.03.2010)
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Journal Article
The Yersinia pestis Effector YopM Inhibits Pyrin Inflammasome Activation
Ratner, Dmitry, Orning, M Pontus A, Proulx, Megan K, Wang, Donghai, Gavrilin, Mikhail A, Wewers, Mark D, Alnemri, Emad S, Johnson, Peter F, Lee, Bettina, Mecsas, Joan, Kayagaki, Nobuhiko, Goguen, Jon D, Lien, Egil
Published in PLoS pathogens (02.12.2016)
Published in PLoS pathogens (02.12.2016)
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Journal Article
Inflammasome priming by lipopolysaccharide is dependent upon ERK signaling and proteasome function
Ghonime, Mohammed G, Shamaa, Obada R, Das, Srabani, Eldomany, Ramadan A, Fernandes-Alnemri, Teresa, Alnemri, Emad S, Gavrilin, Mikhail A, Wewers, Mark D
Published in The Journal of immunology (1950) (15.04.2014)
Published in The Journal of immunology (1950) (15.04.2014)
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Journal Article
Chloride sensing by WNK1 regulates NLRP3 inflammasome activation and pyroptosis
Mayes-Hopfinger, Lindsey, Enache, Aura, Xie, Jian, Huang, Chou-Long, Köchl, Robert, Tybulewicz, Victor L. J., Fernandes-Alnemri, Teresa, Alnemri, Emad S.
Published in Nature communications (27.07.2021)
Published in Nature communications (27.07.2021)
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Journal Article
The AIM2 inflammasome is critical for innate immunity to Francisella tularensis
Fernandes-Alnemri, Teresa, Datta, Pinaki, Huang, Lan, Juliana, Christine, Eisenlohr, Laurence, Yu, Je-Wook, Landel, Carlisle P, Alnemri, Emad S, Kang, Seokwon, Solorzano, Leobaldo, McCormick, Margaret, Wu, Jianghong, McDermott, Erin
Published in Nature immunology (01.05.2010)
Published in Nature immunology (01.05.2010)
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Journal Article
Raptinal Induces Gasdermin E-Dependent Pyroptosis in Naïve and Therapy-Resistant Melanoma
Vernon, Megane, Wilski, Nicole A, Kotas, Daniel, Cai, Weijia, Pomante, Danielle, Tiago, Manoela, Alnemri, Emad S, Aplin, Andrew E
Published in Molecular cancer research (02.12.2022)
Published in Molecular cancer research (02.12.2022)
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Journal Article
Inactivation of Omi/HtrA2 protease leads to the deregulation of mitochondrial Mulan E3 ubiquitin ligase and increased mitophagy
Cilenti, Lucia, Ambivero, Camilla T., Ward, Nathan, Alnemri, Emad S., Germain, Doris, Zervos, Antonis S.
Published in Biochimica et biophysica acta (01.07.2014)
Published in Biochimica et biophysica acta (01.07.2014)
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