Supplementing clinical lactation studies with PBPK modeling to inform drug therapy in lactating mothers: Prediction of primaquine exposure as a case example
Pan, Xian, Abduljalil, Khaled, Almond, Lisa M., Pansari, Amita, Yeo, Karen Rowland
Published in CPT: pharmacometrics and systems pharmacology (01.03.2024)
Published in CPT: pharmacometrics and systems pharmacology (01.03.2024)
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Journal Article
PBPK‐led assessment of antimalarial drugs as candidates for Covid‐19: Simulating concentrations at the site of action to inform repurposing strategies
Abla, Nada, Almond, Lisa M., Bonner, Jennifer J., Richardson, Naomi, Wells, Timothy N. C., Möhrle, Jörg J.
Published in Clinical and translational science (01.07.2024)
Published in Clinical and translational science (01.07.2024)
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Journal Article
Development and application of a PBPK modeling strategy to support antimalarial drug development
Abla, Nada, Howgate, Eleanor, Rowland‐Yeo, Karen, Dickins, Maurice, Bergagnini‐Kolev, Mackenzie C., Chen, Kuan‐Fu, McFeely, Savannah, Bonner, Jennifer J., Santos, Laura G. A., Gobeau, Nathalie, Burt, Howard, Barter, Zoe, Jones, Hannah M., Wesche, David, Charman, Susan A., Möhrle, Jörg J., Burrows, Jeremy N., Almond, Lisa M.
Published in CPT: pharmacometrics and systems pharmacology (01.09.2023)
Published in CPT: pharmacometrics and systems pharmacology (01.09.2023)
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Journal Article
Physiologically‐Based Pharmacokinetic‐Led Guidance for Patients With Cystic Fibrosis Taking Elexacaftor‐Tezacaftor‐Ivacaftor With Nirmatrelvir‐Ritonavir for the Treatment of COVID‐19
Hong, Eunjin, Almond, Lisa M., Chung, Peter S., Rao, Adupa P., Beringer, Paul M.
Published in Clinical pharmacology and therapeutics (01.06.2022)
Published in Clinical pharmacology and therapeutics (01.06.2022)
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Journal Article
Impact of Disease on Plasma and Lung Exposure of Chloroquine, Hydroxychloroquine and Azithromycin: Application of PBPK Modeling
Rowland Yeo, Karen, Zhang, Mian, Pan, Xian, Ban Ke, Alice, Jones, Hannah M., Wesche, David, Almond, Lisa M.
Published in Clinical pharmacology and therapeutics (01.11.2020)
Published in Clinical pharmacology and therapeutics (01.11.2020)
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Journal Article
Safety of elexacaftor/tezacaftor/ivacaftor dose reduction: Mechanistic exploration through physiologically based pharmacokinetic modeling and a clinical case series
Hong, Eunjin, Li, Regina, Shi, Alan, Almond, Lisa M., Wang, Joshua, Khudari, Amin Z., Haddad, Soumar, Sislyan, Sarkis, Angelich, Marissa, Chung, Peter S., Rao, Adupa P., Beringer, Paul M.
Published in Pharmacotherapy (01.04.2023)
Published in Pharmacotherapy (01.04.2023)
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Journal Article
Prediction of Drug-Drug Interactions Arising from CYP3A induction Using a Physiologically Based Dynamic Model
Almond, Lisa M, Mukadam, Sophie, Gardner, Iain, Okialda, Krystle, Wong, Susan, Hatley, Oliver, Tay, Suzanne, Rowland-Yeo, Karen, Jamei, Masoud, Rostami-Hodjegan, Amin, Kenny, Jane R
Published in Drug metabolism and disposition (01.06.2016)
Published in Drug metabolism and disposition (01.06.2016)
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Journal Article
Incorporating population variability and susceptible subpopulations into dosimetry for high-throughput toxicity testing
Wetmore, Barbara A, Allen, Brittany, Clewell, 3rd, Harvey J, Parker, Timothy, Wambaugh, John F, Almond, Lisa M, Sochaski, Mark A, Thomas, Russell S
Published in Toxicological sciences (01.11.2014)
Published in Toxicological sciences (01.11.2014)
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Journal Article
Application of a Systems Approach to the Bottom-Up Assessment of Pharmacokinetics in Obese Patients: Expected Variations in Clearance
Ghobadi, Cyrus, Johnson, Trevor N., Aarabi, Mohsen, Almond, Lisa M., Allabi, Aurel Constant, Rowland-Yeo, Karen, Jamei, Masoud, Rostami-Hodjegan, Amin
Published in Clinical pharmacokinetics (01.12.2011)
Published in Clinical pharmacokinetics (01.12.2011)
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Journal Article
Intracellular and plasma pharmacokinetics of nevirapine in human immunodeficiency virus-infected individuals
Almond, Lisa M, Edirisinghe, Damitha, Dalton, Mark, Bonington, Alec, Back, David J, Khoo, Saye H
Published in Clinical pharmacology and therapeutics (01.08.2005)
Published in Clinical pharmacology and therapeutics (01.08.2005)
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Journal Article
The relationship between nevirapine plasma concentrations and abnormal liver function tests
Almond, Lisa M, Boffito, Marta, Hoggard, Patrick G, Bonora, Stefano, Raiteri, Riccardo, Reynolds, Helen E, Garazzino, Silvia, Sinicco, Alessandro, Khoo, Saye H, Back, David J, Di Perri, Giovanni
Published in AIDS research and human retroviruses (01.07.2004)
Published in AIDS research and human retroviruses (01.07.2004)
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Journal Article
A tutorial on physiologically based pharmacokinetic approaches in lactation research
Pansari, Amita, Pan, Xian, Almond, Lisa M, Rowland-Yeo, Karen
Published in CPT: pharmacometrics and systems pharmacology (16.09.2024)
Published in CPT: pharmacometrics and systems pharmacology (16.09.2024)
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Journal Article
Time-dependent changes in HIV nucleoside analogue phosphorylation and the effect of hydroxyurea
HOGGARD, Patrick G, KEWN, Stephen, KHOO, Saye H, MAHERBE, Anlie, WOOD, Robin, ALMOND, Lisa M, SALES, Sean D, GOULD, Jayne, LOU, Yu, DE VRIES, Corry, BACK, David J
Published in AIDS (London) (06.12.2002)
Published in AIDS (London) (06.12.2002)
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Journal Article
Application of a Systems Approach to the Bottom-Up Assessment of Pharmacokinetics in Obese Patients
Ghobadi, Cyrus, Johnson, Trevor N, Aarabi, Mohsen, Almond, Lisa M, Allabi, Aurel Constant, Rowland-Yeo, Karen, Jamei, Masoud, Rostami-Hodjegan, Amin
Published in Clinical pharmacokinetics (01.12.2011)
Published in Clinical pharmacokinetics (01.12.2011)
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Journal Article