Multiorgan and Renal Tropism of SARS-CoV-2
Puelles, Victor G, Lütgehetmann, Marc, Lindenmeyer, Maja T, Sperhake, Jan P, Wong, Milagros N, Allweiss, Lena, Chilla, Silvia, Heinemann, Axel, Wanner, Nicola, Liu, Shuya, Braun, Fabian, Lu, Shun, Pfefferle, Susanne, Schröder, Ann S, Edler, Carolin, Gross, Oliver, Glatzel, Markus, Wichmann, Dominic, Wiech, Thorsten, Kluge, Stefan, Pueschel, Klaus, Aepfelbacher, Martin, Huber, Tobias B
Published in New England Journal of Medicine (06.08.2020)
Published in New England Journal of Medicine (06.08.2020)
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Proliferation of primary human hepatocytes and prevention of hepatitis B virus reinfection efficiently deplete nuclear cccDNA in vivo
Allweiss, Lena, Volz, Tassilo, Giersch, Katja, Kah, Janine, Raffa, Giuseppina, Petersen, Joerg, Lohse, Ansgar W, Beninati, Concetta, Pollicino, Teresa, Urban, Stephan, Lütgehetmann, Marc, Dandri, Maura
Published in Gut (01.03.2018)
Published in Gut (01.03.2018)
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Human liver chimeric mice as a new model of chronic hepatitis E virus infection and preclinical drug evaluation
Allweiss, Lena, Gass, Sofia, Giersch, Katja, Groth, Anne, Kah, Janine, Volz, Tassilo, Rapp, Gianna, Schöbel, Anja, Lohse, Ansgar W, Polywka, Susanne, Pischke, Sven, Herker, Eva, Dandri, Maura, Lütgehetmann, Marc
Published in Journal of hepatology (01.05.2016)
Published in Journal of hepatology (01.05.2016)
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Hepatitis Delta co-infection in humanized mice leads to pronounced induction of innate immune responses in comparison to HBV mono-infection
Giersch, Katja, Allweiss, Lena, Volz, Tassilo, Helbig, Martina, Bierwolf, Jeanette, Lohse, Ansgar W, Pollok, Joerg M, Petersen, Joerg, Dandri, Maura, Lütgehetmann, Marc
Published in Journal of hepatology (01.08.2015)
Published in Journal of hepatology (01.08.2015)
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Humanized chimeric uPA mouse model for the study of hepatitis B and D virus interactions and preclinical drug evaluation
Lütgehetmann, Marc, Mancke, Lida V., Volz, Tassilo, Helbig, Martina, Allweiss, Lena, Bornscheuer, Till, Pollok, Joerg M., Lohse, Ansgar W., Petersen, J., Urban, Stephan, Dandri, Maura
Published in Hepatology (Baltimore, Md.) (01.03.2012)
Published in Hepatology (Baltimore, Md.) (01.03.2012)
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Hepatitis B Virus Particles Activate Toll‐Like Receptor 2 Signaling Initially Upon Infection of Primary Human Hepatocytes
Zhang, Zhenhua, Trippler, Martin, Real, Catherine I., Werner, Melanie, Luo, Xufeng, Schefczyk, Stefan, Kemper, Thekla, Anastasiou, Olympia E., Ladiges, Yvonne, Treckmann, Juergen, Paul, Andreas, Baba, Hideo A., Allweiss, Lena, Dandri, Maura, Gerken, Guido, Wedemeyer, Heiner, Schlaak, Joerg F., Lu, Mengji, Broering, Ruth
Published in Hepatology (Baltimore, Md.) (01.09.2020)
Published in Hepatology (Baltimore, Md.) (01.09.2020)
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Binding of hepatitis B virus to its cellular receptor alters the expression profile of genes of bile acid metabolism
Oehler, Nicola, Volz, Tassilo, Bhadra, Oliver D., Kah, Janine, Allweiss, Lena, Giersch, Katja, Bierwolf, Jeanette, Riecken, Kristoffer, Pollok, Jörg M., Lohse, Ansgar W., Fehse, Boris, Petersen, Joerg, Urban, Stephan, Lütgehetmann, Marc, Heeren, Joerg, Dandri, Maura
Published in Hepatology (Baltimore, Md.) (01.11.2014)
Published in Hepatology (Baltimore, Md.) (01.11.2014)
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Multiscale modeling of HBV infection integrating intra- and intercellular viral propagation to analyze extracellular viral markers
Kitagawa, Kosaku, Kim, Kwang Su, Iwamoto, Masashi, Hayashi, Sanae, Park, Hyeongki, Nishiyama, Takara, Nakamura, Naotoshi, Fujita, Yasuhisa, Nakaoka, Shinji, Aihara, Kazuyuki, Perelson, Alan S, Allweiss, Lena, Dandri, Maura, Watashi, Koichi, Tanaka, Yasuhito, Iwami, Shingo
Published in PLoS computational biology (11.03.2024)
Published in PLoS computational biology (11.03.2024)
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Both interferon alpha and lambda can reduce all intrahepatic HDV infection markers in HBV/HDV infected humanized mice
Giersch, Katja, Homs, Maria, Volz, Tassilo, Helbig, Martina, Allweiss, Lena, Lohse, Ansgar W., Petersen, Jörg, Buti, Maria, Pollicino, Teresa, Sureau, Camille, Dandri, Maura, Lütgehetmann, Marc
Published in Scientific reports (16.06.2017)
Published in Scientific reports (16.06.2017)
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Down-regulation of cell membrane localized NTCP expression in proliferating hepatocytes prevents hepatitis B virus infection
Yan, Ying, Allweiss, Lena, Yang, Danli, Kang, Jingting, Wang, Jianwen, Qian, Xiangjun, Zhang, Ting, Liu, Hui, Wang, Lu, Liu, Shuhong, Sui, Jianhua, Chen, Xiangmei, Dandri, Maura, Zhao, Jingmin, Lu, Fengmin
Published in Emerging microbes & infections (01.01.2019)
Published in Emerging microbes & infections (01.01.2019)
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Strong Replication Interference Between Hepatitis Delta Viruses in Human Liver Chimeric Mice
Giersch, Katja, Hermanussen, Lennart, Volz, Tassilo, Volmari, Annika, Allweiss, Lena, Sureau, Camille, Casey, John, Huang, Jiabin, Fischer, Nicole, Lütgehetmann, Marc, Dandri, Maura
Published in Frontiers in microbiology (08.07.2021)
Published in Frontiers in microbiology (08.07.2021)
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Strain-specific responsiveness of hepatitis D virus to interferon-alpha treatment
Giersch, Katja, Perez-Gonzalez, Paulina, Hendricks, Lennart, Goldmann, Nora, Kolbe, Jonathan, Hermanussen, Lennart, Bockmann, Jan-Hendrick, Volz, Tassilo, Volmari, Annika, Allweiss, Lena, Petersen, Joerg, Glebe, Dieter, Lütgehetmann, Marc, Dandri, Maura
Published in JHEP reports (01.04.2023)
Published in JHEP reports (01.04.2023)
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Specificity protein 2 (Sp2) is essential for mouse development and autonomous proliferation of mouse embryonic fibroblasts
Baur, Frank, Nau, Kerstin, Sadic, Dennis, Allweiss, Lena, Elsässer, Hans-Peter, Gillemans, Nynke, de Wit, Ton, Krüger, Imme, Vollmer, Marion, Philipsen, Sjaak, Suske, Guntram
Published in PloS one (08.03.2010)
Published in PloS one (08.03.2010)
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Serum HBV pgRNA as a clinical marker for cccDNA activity
Giersch, Katja, Allweiss, Lena, Volz, Tassilo, Dandri, Maura, Lütgehetmann, Marc
Published in Journal of hepatology (01.02.2017)
Published in Journal of hepatology (01.02.2017)
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Neuropathology of patients with COVID-19 in Germany: a post-mortem case series
Matschke, Jakob, Lütgehetmann, Marc, Hagel, Christian, Sperhake, Jan P, Schröder, Ann Sophie, Edler, Carolin, Mushumba, Herbert, Fitzek, Antonia, Allweiss, Lena, Dandri, Maura, Dottermusch, Matthias, Heinemann, Axel, Pfefferle, Susanne, Schwabenland, Marius, Sumner Magruder, Daniel, Bonn, Stefan, Prinz, Marco, Gerloff, Christian, Püschel, Klaus, Krasemann, Susanne, Aepfelbacher, Martin, Glatzel, Markus
Published in Lancet neurology (01.11.2020)
Published in Lancet neurology (01.11.2020)
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IFN-α inhibits HBV transcription and replication in cell culture and in humanized mice by targeting the epigenetic regulation of the nuclear cccDNA minichromosome
Belloni, Laura, Allweiss, Lena, Guerrieri, Francesca, Pediconi, Natalia, Volz, Tassilo, Pollicino, Teresa, Petersen, Joerg, Raimondo, Giovanni, Dandri, Maura, Levrero, Massimo
Published in The Journal of clinical investigation (01.02.2012)
Published in The Journal of clinical investigation (01.02.2012)
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