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Palencia, Andrés, Liu, Ru-Juan, Lukarska, Maria, Gut, Jiri, Bougdour, Alexandre, Touquet, Bastien, Wang, En-Duo, Li, Xianfeng, Alley, M R K, Freund, Yvonne R, Rosenthal, Philip J, Hakimi, Mohamed-Ali, Cusack, Stephen
Published in Antimicrobial agents and chemotherapy (01.10.2016)
Published in Antimicrobial agents and chemotherapy (01.10.2016)
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Epetraborole, a leucyl-tRNA synthetase inhibitor, demonstrates murine efficacy, enhancing the in vivo activity of ceftazidime against Burkholderia pseudomallei, the causative agent of melioidosis
Cummings, Jason E, Lunde, Christopher S, Alley, M R K, Slayden, Richard A
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Published in PLoS neglected tropical diseases (01.11.2023)
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Discovery of a Potent and Specific M. tuberculosis Leucyl-tRNA Synthetase Inhibitor: (S)‑3-(Aminomethyl)-4-chloro-7-(2-hydroxyethoxy)benzo[c][1,2]oxaborol-1(3H)‑ol (GSK656)
Li, Xianfeng, Hernandez, Vincent, Rock, Fernando L, Choi, Wai, Mak, Yvonne S. L, Mohan, Manisha, Mao, Weimin, Zhou, Yasheen, Easom, Eric E, Plattner, Jacob J, Zou, Wuxin, Pérez-Herrán, Esther, Giordano, Ilaria, Mendoza-Losana, Alfonso, Alemparte, Carlos, Rullas, Joaquín, Angulo-Barturen, Iñigo, Crouch, Sabrinia, Ortega, Fátima, Barros, David, Alley, M. R. K
Published in Journal of medicinal chemistry (12.10.2017)
Published in Journal of medicinal chemistry (12.10.2017)
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Clinical and veterinary trypanocidal benzoxaboroles target CPSF3
Wall, Richard J., Rico, Eva, Lukac, Iva, Zuccotto, Fabio, Elg, Sara, Gilbert, Ian H., Freund, Yvonne, Alley, M. R. K., Field, Mark C., Wyllie, Susan, Horn, David
Published in Proceedings of the National Academy of Sciences - PNAS (18.09.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (18.09.2018)
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Antimalarial Benzoxaboroles Target Plasmodium falciparum Leucyl-tRNA Synthetase
Sonoiki, Ebere, Palencia, Andres, Guo, Denghui, Ahyong, Vida, Dong, Chen, Li, Xianfeng, Hernandez, Vincent S, Zhang, Yong-Kang, Choi, Wai, Gut, Jiri, Legac, Jennifer, Cooper, Roland, Alley, M R K, Freund, Yvonne R, DeRisi, Joseph, Cusack, Stephen, Rosenthal, Philip J
Published in Antimicrobial agents and chemotherapy (01.08.2016)
Published in Antimicrobial agents and chemotherapy (01.08.2016)
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Groundwater depletion and sustainability of irrigation in the US High Plains and Central Valley
Scanlon, Bridget R, Faunt, Claudia C, Longuevergne, Laurent, Reedy, Robert C, Alley, William M, McGuire, Virginia L, McMahon, Peter B
Published in Proceedings of the National Academy of Sciences - PNAS (12.06.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (12.06.2012)
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Antifungal Agent Inhibits an Aminoacyl-tRNA Synthetase by Trapping tRNA in the Editing Site
Rock, Fernando L, Mao, Weimin, Yaremchuk, Anya, Tukalo, Mikhail, Crépin, Thibaut, Zhou, Huchen, Zhang, Yong-Kang, Hernandez, Vincent, Akama, Tsutomu, Baker, Stephen J, Plattner, Jacob J, Shapiro, Lucy, Martinis, Susan A, Benkovic, Stephen J, Cusack, Stephen, Alley, M.R.K
Published in Science (American Association for the Advancement of Science) (22.06.2007)
Published in Science (American Association for the Advancement of Science) (22.06.2007)
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Discovery of Novel Oral Protein Synthesis Inhibitors of Mycobacterium tuberculosis That Target Leucyl-tRNA Synthetase
Palencia, Andrés, Li, Xianfeng, Bu, Wei, Choi, Wai, Ding, Charles Z, Easom, Eric E, Feng, Lisa, Hernandez, Vincent, Houston, Paul, Liu, Liang, Meewan, Maliwan, Mohan, Manisha, Rock, Fernando L, Sexton, Holly, Zhang, Suoming, Zhou, Yasheen, Wan, Baojie, Wang, Yuehong, Franzblau, Scott G, Woolhiser, Lisa, Gruppo, Veronica, Lenaerts, Anne J, O'Malley, Theresa, Parish, Tanya, Cooper, Christopher B, Waters, M Gerard, Ma, Zhenkun, Ioerger, Thomas R, Sacchettini, James C, Rullas, Joaquín, Angulo-Barturen, Iñigo, Pérez-Herrán, Esther, Mendoza, Alfonso, Barros, David, Cusack, Stephen, Plattner, Jacob J, Alley, M R K
Published in Antimicrobial agents and chemotherapy (01.10.2016)
Published in Antimicrobial agents and chemotherapy (01.10.2016)
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A potent antimalarial benzoxaborole targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue
Sonoiki, Ebere, Ng, Caroline L., Lee, Marcus C. S., Guo, Denghui, Zhang, Yong-Kang, Zhou, Yasheen, Alley, M. R. K., Ahyong, Vida, Sanz, Laura M., Lafuente-Monasterio, Maria Jose, Dong, Chen, Schupp, Patrick G., Gut, Jiri, Legac, Jenny, Cooper, Roland A., Gamo, Francisco-Javier, DeRisi, Joseph, Freund, Yvonne R., Fidock, David A., Rosenthal, Philip J.
Published in Nature communications (06.03.2017)
Published in Nature communications (06.03.2017)
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Discovery of a New Boron-Containing Antifungal Agent, 5-Fluoro-1,3-dihydro-1-hydroxy-2,1- benzoxaborole (AN2690), for the Potential Treatment of Onychomycosis
Baker, Stephen J, Zhang, Yong-Kang, Akama, Tsutomu, Lau, Agnes, Zhou, Huchen, Hernandez, Vincent, Mao, Weimin, Alley, M. R. K, Sanders, Virginia, Plattner, Jacob J
Published in Journal of medicinal chemistry (27.07.2006)
Published in Journal of medicinal chemistry (27.07.2006)
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Potency and Spectrum of Activity of AN3365, a Novel Boron-Containing Protein Synthesis Inhibitor, Tested against Clinical Isolates of Enterobacteriaceae and Nonfermentative Gram-Negative Bacilli
MENDES, Rodrigo E, ALLEY, M. R. K, SADER, Helio S, BIEDENBACH, Douglas J, JONES, Ronald N
Published in Antimicrobial Agents and Chemotherapy (01.06.2013)
Published in Antimicrobial Agents and Chemotherapy (01.06.2013)
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Discovery of a Novel Class of Boron-Based Antibacterials with Activity against Gram-Negative Bacteria
HERNANDEZ, Vincent, CREPIN, Thibaut, MEEWAN, Maliwan, MOHAN, Manisha, WEIMIN MAO, ROCK, Fernando L, SEXTON, Holly, SHEORAN, Anita, YANCHEN ZHANG, ZHANG, Yong-Kang, ZHOU, Yasheen, NIEMAN, James A, PALENCIA, Andrés, MAHIPAL REDDY ANUGULA, EL MEHDI KERAMANE, SAVARIRAJ, Kingsley, SHEKHAR REDDY, D, SHARMA, Rashmi, SUBEDI, Rajendra, SINGH, Rajeshwar, O'LEARY, Ann, SIMON, Nerissa L, DE MARSH, Peter L, CUSACK, Stephen, MUSHTAQ, Shazad, WARNER, Marina, LIVERMORE, David M, ALLEY, M. R. K, PLATTNER, Jacob J, AKAMA, Tsutomu, BAKER, Stephen J, WEI BU, LISA FENG, FREUND, Yvonne R, LIANG LIU
Published in Antimicrobial Agents and Chemotherapy (01.03.2013)
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Efficacy and Improved Resistance Potential of a Cofactor-Independent InhA Inhibitor of Mycobacterium tuberculosis in the C3HeB/FeJ Mouse Model
Robertson, Gregory T, Ektnitphong, Victoria A, Scherman, Michael S, McNeil, Matthew B, Dennison, Devon, Korkegian, Aaron, Smith, Anthony J, Halladay, Jason, Carter, David S, Xia, Yi, Zhou, Yasheen, Choi, Wai, Berry, Pamela W, Mao, Weimin, Hernandez, Vincent, Alley, M R K, Parish, Tanya, Lenaerts, Anne J
Published in Antimicrobial agents and chemotherapy (01.04.2019)
Published in Antimicrobial agents and chemotherapy (01.04.2019)
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Boron-based phosphodiesterase inhibitors show novel binding of boron to PDE4 bimetal center
Freund, Yvonne R., Akama, Tsutomu, Alley, M.R.K., Antunes, Joana, Dong, Chen, Jarnagin, Kurt, Kimura, Richard, Nieman, James A., Maples, Kirk R., Plattner, Jacob J., Rock, Fernando, Sharma, Rashmi, Singh, Rajeshwar, Sanders, Virginia, Zhou, Yasheen
Published in FEBS letters (21.09.2012)
Published in FEBS letters (21.09.2012)
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Electric Properties Change during Morphological Evolution of CeO2 Nanostructures: Synergy between Bulk and Surface Defects
Macchi, Carlos, Procópio, Alley M. S., Rocha, Leandro S. R., Ortega, Pedro P., Aldao, Celso M., Granone, Luis I., Nascimento, Hugo M. S., Longo, Elson, Castro, Miriam S., Ivorra, Fernando D., Somoza, Alberto, Moura, Francisco, Ponce, Miguel A.
Published in ACS omega (15.10.2024)
Published in ACS omega (15.10.2024)
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Synthesis and SAR of novel benzoxaboroles as a new class of β-lactamase inhibitors
Xia, Yi, Cao, Kathy, Zhou, Yasheen, Alley, M.R.K., Rock, Fernando, Mohan, Manisha, Meewan, Maliwan, Baker, Stephen J., Lux, Sarah, Ding, Charles Z., Jia, Guofeng, Kully, Maureen, Plattner, Jacob J.
Published in Bioorganic & medicinal chemistry letters (15.04.2011)
Published in Bioorganic & medicinal chemistry letters (15.04.2011)
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A Novel 6-Benzyl Ether Benzoxaborole Is Active against Mycobacterium tuberculosis In Vitro
Patel, Nipul, O'Malley, Theresa, Zhang, Yong-Kang, Xia, Yi, Sunde, Bjorn, Flint, Lindsay, Korkegian, Aaron, Ioerger, Thomas R, Sacchettini, Jim, Alley, M R K, Parish, Tanya
Published in Antimicrobial agents and chemotherapy (01.09.2017)
Published in Antimicrobial agents and chemotherapy (01.09.2017)
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