A Highly Efficient Human Pluripotent Stem Cell Microglia Model Displays a Neuronal-Co-culture-Specific Expression Profile and Inflammatory Response
Haenseler, Walther, Sansom, Stephen N., Buchrieser, Julian, Newey, Sarah E., Moore, Craig S., Nicholls, Francesca J., Chintawar, Satyan, Schnell, Christian, Antel, Jack P., Allen, Nicholas D., Cader, M. Zameel, Wade-Martins, Richard, James, William S., Cowley, Sally A.
Published in Stem cell reports (06.06.2017)
Published in Stem cell reports (06.06.2017)
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Mutant huntingtin confers cell-autonomous phenotypes on Huntington’s disease iPSC-derived microglia
Stöberl, Nina, Donaldson, Jasmine, Binda, Caroline S., McAllister, Branduff, Hall-Roberts, Hazel, Jones, Lesley, Massey, Thomas H., Allen, Nicholas D.
Published in Scientific reports (22.11.2023)
Published in Scientific reports (22.11.2023)
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FAN1 controls mismatch repair complex assembly via MLH1 retention to stabilize CAG repeat expansion in Huntington’s disease
Goold, Robert, Hamilton, Joseph, Menneteau, Thomas, Flower, Michael, Bunting, Emma L., Aldous, Sarah G., Porro, Antonio, Vicente, José R., Allen, Nicholas D., Wilkinson, Hilary, Bates, Gillian P., Sartori, Alessandro A., Thalassinos, Konstantinos, Balmus, Gabriel, Tabrizi, Sarah J.
Published in Cell reports (Cambridge) (31.08.2021)
Published in Cell reports (Cambridge) (31.08.2021)
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Huntington's Disease Patient-Derived Astrocytes Display Electrophysiological Impairments and Reduced Neuronal Support
Garcia, Veronica J, Rushton, David J, Tom, Colton M, Allen, Nicholas D, Kemp, Paul J, Svendsen, Clive N, Mattis, Virginia B
Published in Frontiers in neuroscience (28.06.2019)
Published in Frontiers in neuroscience (28.06.2019)
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Nucleosome dynamics of human iPSC during neural differentiation
Harwood, Janet C, Kent, Nicholas A, Allen, Nicholas D, Harwood, Adrian J
Published in EMBO reports (01.06.2019)
Published in EMBO reports (01.06.2019)
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Electric field stimulation boosts neuronal differentiation of neural stem cells for spinal cord injury treatment via PI3K/Akt/GSK-3β/β-catenin activation
Liu, Qian, Telezhkin, Vsevolod, Jiang, Wenkai, Gu, Yu, Wang, Yan, Hong, Wei, Tian, Weiming, Yarova, Polina, Zhang, Gaofeng, Lee, Simon Ming-Yuen, Zhang, Peng, Zhao, Min, Allen, Nicholas D, Hirsch, Emilio, Penninger, Josef, Song, Bing
Published in Cell & bioscience (09.01.2023)
Published in Cell & bioscience (09.01.2023)
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Case Report: Right Insular Stroke Causing Simultaneous Onset of a Functional Vestibular Disorder and Psychiatric Disorder-Persistent Postural-Perceptual Dizziness and Post-stroke Depression
Fipps, David C, Staab, Jeffrey P, Allen, Nicholas D
Published in Frontiers in psychiatry (21.04.2022)
Published in Frontiers in psychiatry (21.04.2022)
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Improving and accelerating the differentiation and functional maturation of human stem cell‐derived neurons: role of extracellular calcium and GABA
Kemp, Paul J., Rushton, David J., Yarova, Polina L., Schnell, Christian, Geater, Charlene, Hancock, Jane M., Wieland, Annalena, Hughes, Alis, Badder, Luned, Cope, Emma, Riccardi, Daniela, Randall, Andrew D., Brown, Jonathan T., Allen, Nicholas D., Telezhkin, Vsevolod
Published in The Journal of physiology (15.11.2016)
Published in The Journal of physiology (15.11.2016)
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Discovery of a Novel Polymer for Human Pluripotent Stem Cell Expansion and Multilineage Differentiation
Celiz, Adam D., Smith, James G. W., Patel, Asha K., Hook, Andrew L., Rajamohan, Divya, George, Vinoj T., Flatt, Luke, Patel, Minal J., Epa, Vidana C., Singh, Taranjit, Langer, Robert, Anderson, Daniel G., Allen, Nicholas D., Hay, David C., Winkler, David A., Barrett, David A., Davies, Martyn C., Young, Lorraine E., Denning, Chris, Alexander, Morgan R.
Published in Advanced materials (Weinheim) (15.07.2015)
Published in Advanced materials (Weinheim) (15.07.2015)
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Aberrant Development Corrected in Adult-Onset Huntington's Disease iPSC-Derived Neuronal Cultures via WNT Signaling Modulation
Smith-Geater, Charlene, Hernandez, Sarah J., Lim, Ryan G., Adam, Miriam, Wu, Jie, Stocksdale, Jennifer T., Wassie, Brook T., Gold, Maxwell Philip, Wang, Keona Q., Miramontes, Ricardo, Kopan, Lexi, Orellana, Iliana, Joy, Shona, Kemp, Paul J., Allen, Nicholas D., Fraenkel, Ernest, Thompson, Leslie M.
Published in Stem cell reports (10.03.2020)
Published in Stem cell reports (10.03.2020)
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Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer's disease
Baker, Emily, Sims, Rebecca, Leonenko, Ganna, Frizzati, Aura, Harwood, Janet C, Grozeva, Detelina, Morgan, Kevin, Passmore, Peter, Holmes, Clive, Powell, John, Brayne, Carol, Gill, Michael, Mead, Simon, Bossù, Paola, Spalletta, Gianfranco, Goate, Alison M, Cruchaga, Carlos, Maier, Wolfgang, Heun, Reinhard, Jessen, Frank, Peters, Oliver, Dichgans, Martin, FröLich, Lutz, Ramirez, Alfredo, Jones, Lesley, Hardy, John, Ivanov, Dobril, Hill, Matthew, Holmans, Peter, Allen, Nicholas D, Morgan, B Paul, Seshadri, Sudha, Schellenberg, Gerard D, Amouyel, Philippe, Williams, Julie, Escott-Price, Valentina
Published in PloS one (08.07.2019)
Published in PloS one (08.07.2019)
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Influence of Pressure on the Composition of Gaseous Reference Materials
Brewer, Paul J, Brown, Richard J. C, Resner, Kate V, Hill-Pearce, Ruth E, Worton, David R, Allen, Nicholas D. C, Blakley, Kevin C, Benucci, Daniel, Ellison, Matthew R
Published in Analytical chemistry (Washington) (06.03.2018)
Published in Analytical chemistry (Washington) (06.03.2018)
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Nuclear ERK1/2 signaling potentiation enhances neuroprotection and cognition via Importinα1/KPNA2
Indrigo, Marzia, Morella, Ilaria, Orellana, Daniel, d'Isa, Raffaele, Papale, Alessandro, Parra, Riccardo, Gurgone, Antonia, Lecca, Daniela, Cavaccini, Anna, Tigaret, Cezar M, Cagnotto, Alfredo, Jones, Kimberley, Brooks, Simon, Ratto, Gian Michele, Allen, Nicholas D, Lelos, Mariah J, Middei, Silvia, Giustetto, Maurizio, Carta, Anna R, Tonini, Raffaella, Salmona, Mario, Hall, Jeremy, Thomas, Kerrie, Brambilla, Riccardo, Fasano, Stefania
Published in EMBO molecular medicine (08.11.2023)
Published in EMBO molecular medicine (08.11.2023)
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Early transcriptional changes linked to naturally occurring Huntington's disease mutations in neural derivatives of human embryonic stem cells
FEYEUX, Maxime, BOURGOIS-ROCHA, Fany, JONES, Lesley, PESCHANSKI, Marc, ALLEN, Nicholas D, PERRIER, Anselme L, REDFERN, Amanda, GILES, Peter, LEFORT, Nathalie, AUBERT, Sophie, BONNEFOND, Caroline, BUGI, Aurore, RUIZ, Marta, DEGLON, Nicole
Published in Human molecular genetics (01.09.2012)
Published in Human molecular genetics (01.09.2012)
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Activin/Nodal inhibition alone accelerates highly efficient neural conversion from human embryonic stem cells and imposes a caudal positional identity
Patani, Rickie, Compston, Alastair, Puddifoot, Clare A, Wyllie, David J A, Hardingham, Giles E, Allen, Nicholas D, Chandran, Siddharthan
Published in PloS one (06.10.2009)
Published in PloS one (06.10.2009)
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First remote sensing observations of trifluoromethane (HFC-23) in the upper troposphere and lower stratosphere
Harrison, Jeremy J., Boone, Christopher D., Brown, Alexander T., Allen, Nicholas D. C., Toon, Geoffrey C., Bernath, Peter F.
Published in Journal of Geophysical Research: Atmospheres (16.03.2012)
Published in Journal of Geophysical Research: Atmospheres (16.03.2012)
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Novel epigenetic clock for fetal brain development predicts prenatal age for cellular stem cell models and derived neurons
Steg, Leonard C, Shireby, Gemma L, Imm, Jennifer, Davies, Jonathan P, Franklin, Alice, Flynn, Robert, Namboori, Seema C, Bhinge, Akshay, Jeffries, Aaron R, Burrage, Joe, Neilson, Grant W A, Walker, Emma M, Perfect, Leo W, Price, Jack, McAlonan, Grainne, Srivastava, Deepak P, Bray, Nicholas J, Cope, Emma L, Jones, Kimberley M, Allen, Nicholas D, Pishva, Ehsan, Dempster, Emma L, Lunnon, Katie, Mill, Jonathan, Hannon, Eilis
Published in Molecular brain (26.06.2021)
Published in Molecular brain (26.06.2021)
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Mice Lacking the Giant Protocadherin mFAT1 Exhibit Renal Slit Junction Abnormalities and a Partially Penetrant Cyclopia and Anophthalmia Phenotype
Ciani, Lorenza, Patel, Anjla, Allen, Nicholas D., ffrench-Constant, Charles
Published in Molecular and Cellular Biology (01.05.2003)
Published in Molecular and Cellular Biology (01.05.2003)
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