Exploring the structural origins of cryptic sites on proteins
Beglov, Dmitri, Hall, David R., Wakefield, Amanda E., Luo, Lingqi, Allen, Karen N., Kozakov, Dima, Whitty, Adrian, Vajda, Sandor
Published in Proceedings of the National Academy of Sciences - PNAS (10.04.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (10.04.2018)
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Journal Article
Construction and Analysis of Two Genome-Scale Deletion Libraries for Bacillus subtilis
Koo, Byoung-Mo, Kritikos, George, Farelli, Jeremiah D., Todor, Horia, Tong, Kenneth, Kimsey, Harvey, Wapinski, Ilan, Galardini, Marco, Cabal, Angelo, Peters, Jason M., Hachmann, Anna-Barbara, Rudner, David Z., Allen, Karen N., Typas, Athanasios, Gross, Carol A.
Published in Cell systems (22.03.2017)
Published in Cell systems (22.03.2017)
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Journal Article
Evolutionary Genomics of the HAD Superfamily: Understanding the Structural Adaptations and Catalytic Diversity in a Superfamily of Phosphoesterases and Allied Enzymes
Burroughs, A. Maxwell, Allen, Karen N., Dunaway-Mariano, Debra, Aravind, L.
Published in Journal of molecular biology (01.09.2006)
Published in Journal of molecular biology (01.09.2006)
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Journal Article
Panoramic view of a superfamily of phosphatases through substrate profiling
Huang, Hua, Pandya, Chetanya, Liu, Chunliang, Al-Obaidi, Nawar F., Wang, Min, Zheng, Li, Keating, Sarah Toews, Aono, Miyuki, Love, James D., Evans, Brandon, Seidel, Ronald D., Hillerich, Brandan S., Garforth, Scott J., Almo, Steven C., Mariano, Patrick S., Dunaway-Mariano, Debra, Allen, Karen N., Farelli, Jeremiah D.
Published in Proceedings of the National Academy of Sciences - PNAS (21.04.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (21.04.2015)
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Journal Article
Ligand deconstruction: Why some fragment binding positions are conserved and others are not
Kozakov, Dima, Hall, David R., Jehle, Stefan, Luo, Lingqi, Ochiana, Stefan O., Jones, Elizabeth V., Pollastri, Michael, Allen, Karen N., Whitty, Adrian, Vajda, Sandor
Published in Proceedings of the National Academy of Sciences - PNAS (19.05.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (19.05.2015)
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Journal Article
Interaction Energetics and Druggability of the Protein–Protein Interaction between Kelch-like ECH-Associated Protein 1 (KEAP1) and Nuclear Factor Erythroid 2 Like 2 (Nrf2)
Zhong, Mengqi, Lynch, Andrew, Muellers, Samantha N, Jehle, Stefan, Luo, Lingqi, Hall, David R, Iwase, Reina, Carolan, James P, Egbert, Megan, Wakefield, Amanda, Streu, Kristina, Harvey, Christine M, Ortet, Paula C, Kozakov, Dima, Vajda, Sandor, Allen, Karen N, Whitty, Adrian
Published in Biochemistry (Easton) (04.02.2020)
Published in Biochemistry (Easton) (04.02.2020)
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Journal Article
Encoded loop-lanthanide-binding tags for long-range distance measurements in proteins by NMR and EPR spectroscopy
Barthelmes, Dominic, Gränz, Markus, Barthelmes, Katja, Allen, Karen N., Imperiali, Barbara, Prisner, Thomas, Schwalbe, Harald
Published in Journal of biomolecular NMR (01.11.2015)
Published in Journal of biomolecular NMR (01.11.2015)
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Journal Article
Phosphoryl group transfer: evolution of a catalytic scaffold
Allen, Karen N., Dunaway-Mariano, Debra
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.09.2004)
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.09.2004)
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Journal Article
Double-Lanthanide-Binding Tags: Design, Photophysical Properties, and NMR Applications
Martin, Langdon J, Hähnke, Martin J, Nitz, Mark, Wöhnert, Jens, Silvaggi, Nicholas R, Allen, Karen N, Schwalbe, Harald, Imperiali, Barbara
Published in Journal of the American Chemical Society (06.06.2007)
Published in Journal of the American Chemical Society (06.06.2007)
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Journal Article
The origin of the electrostatic perturbation in acetoacetate decarboxylase
Ho, Meng-Chiao, Ménétret, Jean-François, Tsuruta, Hiro, Allen, Karen N.
Published in Nature (London) (21.05.2009)
Published in Nature (London) (21.05.2009)
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Journal Article
Quaternary Ammonium Oxidative Demethylation: X-ray Crystallographic, Resonance Raman, and UV–Visible Spectroscopic Analysis of a Rieske-Type Demethylase
Daughtry, Kelly D, Xiao, Youli, Stoner-Ma, Deborah, Cho, Eunsun, Orville, Allen M, Liu, Pinghua, Allen, Karen N
Published in Journal of the American Chemical Society (08.02.2012)
Published in Journal of the American Chemical Society (08.02.2012)
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Journal Article
Divergence of Structure and Function in the Haloacid Dehalogenase Enzyme Superfamily: Bacteroides thetaiotaomicron BT2127 Is an Inorganic Pyrophosphatase
Huang, Hua, Patskovsky, Yury, Toro, Rafael, Farelli, Jeremiah D, Pandya, Chetanya, Almo, Steven C, Allen, Karen N, Dunaway-Mariano, Debra
Published in Biochemistry (Easton) (18.10.2011)
Published in Biochemistry (Easton) (18.10.2011)
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Journal Article
Consequences of domain insertion on sequence-structure divergence in a superfold
Pandya, Chetanya, Brown, Shoshana, Pieper, Ursula, Sali, Andrej, Dunaway-Mariano, Debra, Babbitt, Patricia C, Xia, Yu, Allen, Karen N
Published in Proceedings of the National Academy of Sciences - PNAS (03.09.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (03.09.2013)
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Journal Article
Structure of the trehalose-6-phosphate phosphatase from Brugia malayi reveals key design principles for anthelmintic drugs
Farelli, Jeremiah D, Galvin, Brendan D, Li, Zhiru, Liu, Chunliang, Aono, Miyuki, Garland, Megan, Hallett, Olivia E, Causey, Thomas B, Ali-Reynolds, Alana, Saltzberg, Daniel J, Carlow, Clotilde K S, Dunaway-Mariano, Debra, Allen, Karen N
Published in PLoS pathogens (01.07.2014)
Published in PLoS pathogens (01.07.2014)
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