Phase I dose-escalating trial of Escherichia coli purine nucleoside phosphorylase and fludarabine gene therapy for advanced solid tumors
Rosenthal, E.L., Chung, T.K., Parker, W.B., Allan, P.W., Clemons, L., Lowman, D., Hong, J., Hunt, F.R., Richman, J., Conry, R.M., Mannion, K., Carroll, W.R., Nabell, L., Sorscher, E.J.
Published in Annals of oncology (01.07.2015)
Published in Annals of oncology (01.07.2015)
Get full text
Journal Article
SYNTHESIS AND BIOLOGICAL ACTIVITY OF 2-FLUORO ADENINE AND 6-METHYL PURINE NUCLEOSIDE ANALOGS AS PRODRUGS FOR SUICIDE GENE THERAPY OF CANCER
Silamkoti, A. V., Allan, P. W., Hassan, A. E. A., Fowler, A. T., Sorscher, E. J., Parker, W. B., Secrist, J. A.
Published in Nucleosides, nucleotides & nucleic acids (01.01.2005)
Published in Nucleosides, nucleotides & nucleic acids (01.01.2005)
Get full text
Journal Article
Characterization of a Chinese hamster ovary cell line with acquired resistance to the bisdioxopiperazine dexrazoxane (ICRF-187) catalytic inhibitor of topoisomerase II
Hasinoff, Brian B., Kuschak, Theodore I., Creighton, Andrew M., Fattman, Cheryl L., Allan, William P., Thampatty, Padmakumari, Yalowich, Jack C.
Published in Biochemical pharmacology (15.06.1997)
Published in Biochemical pharmacology (15.06.1997)
Get full text
Journal Article
Toxicity of Cordycepin in Combination with the Adenosine Deaminase Inhibitor 2′-Deoxycoformycin in Beagle Dogs
Rodman, Larry E., Farnell, Daniel R., Coyne, John M., Allan, Paula W., Hill, Donald L., Duncan, Kimberly L.K., Tomaszewski, Joseph E., Smith, Adaline C., Page, John G.
Published in Toxicology and applied pharmacology (01.11.1997)
Published in Toxicology and applied pharmacology (01.11.1997)
Get full text
Journal Article
Differential induction of etoposide-mediated apoptosis in human leukemia HL-60 and K562 cells
Ritke, M K, Rusnak, J M, Lazo, J S, Allan, W P, Dive, C, Heer, S, Yalowich, J C
Published in Molecular pharmacology (01.10.1994)
Get full text
Published in Molecular pharmacology (01.10.1994)
Journal Article
Purine nucleoside phosphorylase inhibitors: biochemical and pharmacological studies with 9-benzyl-9-deazaguanine and related compounds
L L Bennett, Jr, P W Allan, P E Noker, L M Rose, S Niwas, J A Montgomery, M D Erion
Published in The Journal of pharmacology and experimental therapeutics (01.08.1993)
Get full text
Published in The Journal of pharmacology and experimental therapeutics (01.08.1993)
Journal Article
Reduced phosphorylation of topoisomerase II in etoposide-resistant human leukemia K562 cells
Ritke, M K, Allan, W P, Fattman, C, Gunduz, N N, Yalowich, J C
Published in Molecular pharmacology (01.07.1994)
Get full text
Published in Molecular pharmacology (01.07.1994)
Journal Article
Increased c- jun/AP-1 levels in etoposide-resistant human leukemia K562 cells
Ritke, Mary K., Bergoltz, Vladimir V., Allan, William P., Yalowich, Jack C.
Published in Biochemical pharmacology (03.08.1994)
Published in Biochemical pharmacology (03.08.1994)
Get full text
Journal Article
Metabolism in human cells of the D and L enantiomers of the carbocyclic analog of 2'-deoxyguanosine: Substrate activity with deoxycytidine kinase, mitochondrial deoxyguanosine kinase, and 5'-nucleotidase
BENNETT, L. L, ALLAN, P. W, ARNETT, G, SHEALY, Y. F, SHEWACH, D. S, MASON, W. S, FOUREL, I, PARKER, W. B
Published in Antimicrobial agents and chemotherapy (01.05.1998)
Published in Antimicrobial agents and chemotherapy (01.05.1998)
Get full text
Journal Article
Phosphorylation of the enantiomers of the carbocyclic analog of 2'-deoxyguanosine in cells infected with herpes simplex virus type 1 and in uninfected cells. Lack of enantiomeric selectivity with the viral thymidine kinase
L L Bennett, Jr, W B Parker, P W Allan, L M Rose, Y F Shealy, J A Secrist, 3rd, J A Montgomery, G Arnett, R L Kirkman, W M Shannon
Published in Molecular pharmacology (01.12.1993)
Get full text
Published in Molecular pharmacology (01.12.1993)
Journal Article
The histone deacetylase inhibitor sodium butyrate induces DNA topoisomerase II alpha expression and confers hypersensitivity to etoposide in human leukemic cell lines
Kurz, E U, Wilson, S E, Leader, K B, Sampey, B P, Allan, W P, Yalowich, J C, Kroll, D J
Published in Molecular cancer therapeutics (01.12.2001)
Get full text
Published in Molecular cancer therapeutics (01.12.2001)
Journal Article
Antitumor activity of 2-fluoro-2'-deoxyadenosine against tumors that express Escherichia coli purine nucleoside phosphorylase
Parker, William B, Allan, Paula W, Hassan, Abdalla E A, Secrist, 3rd, John A, Sorscher, Eric J, Waud, William R
Published in Cancer gene therapy (01.01.2003)
Published in Cancer gene therapy (01.01.2003)
Get full text
Journal Article
Reduction of phenoxyl radicals of the antitumour agent etoposide (VP-16) by glutathione and protein sulfhydryls in human leukaemia cells: Implications for cytotoxicity
Yalowich, J.C., Tyurina, Y.Y., Tyurin, V.A., Allan, W.P., Kagan, V.E.
Published in Toxicology in vitro (01.02.1996)
Published in Toxicology in vitro (01.02.1996)
Get full text
Journal Article