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A first-in-man phase I/II study of OBI-3424, an AKR1C3-selective bis-alkylating agent prodrug, in subjects with advanced cancer, including hepatocellular carcinoma (HCC) and castrate-resistant prostate cancer (CRPC)
Tsimberidou, Apostolia Maria, Verschraegen, Claire F., Hsu, Pei, Pearce, Tillman E.
Published in Journal of clinical oncology (20.05.2020)
Published in Journal of clinical oncology (20.05.2020)
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Methoxyamine sensitizes the resistant glioblastoma T98G cell line to the alkylating agent temozolomide
Montaldi, Ana P., Sakamoto-Hojo, Elza T.
Published in Clinical and experimental medicine (01.11.2013)
Published in Clinical and experimental medicine (01.11.2013)
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Mature Follow up from a Phase 2 Study of PI3K-Delta Inhibitor Idelalisib in Patients with Double (Rituximab and Alkylating agent)-Refractory Indolent B-Cell Non-Hodgkin Lymphoma (iNHL)
Gopal, Ajay K., Kahl, Brad S., de Vos, Sven, Wagner-Johnston, Nina D., Schuster, Stephen J., Jurczak, Wojciech, Flinn, Ian W., Flowers, Christopher R., Martin, Peter, Viardot, Andreas, Blum, Kristie A., Goy, Andre, Davies, Andrew, Zinzani, Pier Luigi, Dreyling, Martin H., Holes, Leanne M., Sorensen, Bess, Godfrey, Wayne R., Salles, Gilles Andre
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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ET-18VAL-083 IS A NOVEL N7 ALKYLATING AGENT THAT INHIBITS THE GROWTH OF GLIOMA STEM AND NON-STEM CULTURES, INCLUDING TEMOZOLOMIDE-RESISTANT LINES
Fouse, Shaun, Steino, Anne, Butowski, Nicholas, Bacha, Jeffrey, Brown, Dennis, Costello, Joseph
Published in Neuro-oncology (Charlottesville, Va.) (01.11.2014)
Published in Neuro-oncology (Charlottesville, Va.) (01.11.2014)
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ET-18 VAL-083 IS A NOVEL N7 ALKYLATING AGENT THAT INHIBITS THE GROWTH OF GLIOMA STEM AND NON-STEM CULTURES, INCLUDING TEMOZOLOMIDE-RESISTANT LINES
Fouse, S., Steino, A., Butowski, N., Bacha, J., Brown, D., Costello, J.
Published in Neuro-oncology (Charlottesville, Va.) (01.11.2014)
Published in Neuro-oncology (Charlottesville, Va.) (01.11.2014)
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In vitro susceptibilities in lymphocytes from mothers and cord blood to the monofunctional alkylating agent EMS
Wyatt, NP, Falque-Gonzalez, C, Farrar, D, Tuffnell, D, Whitelaw, D, Knudsen, LE, Anderson, D
Published in Mutagenesis (01.03.2007)
Published in Mutagenesis (01.03.2007)
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Clerocidin-mediated DNA footprinting discriminates among different G-quadruplex conformations and detects tetraplex folding in a duplex environment
Nadai, Matteo, Sattin, Giovanna, Palù, Giorgio, Palumbo, Manlio, Richter, Sara N.
Published in Biochimica et biophysica acta (01.10.2013)
Published in Biochimica et biophysica acta (01.10.2013)
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alkylating agent
Published in Oxford Dictionary of Biochemistry and Molecular Biology
(01.01.2006)
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Pharmacotherapy of scleritis: current paradigms and future directions
Beardsley, Robert M, Suhler, Eric B, Rosenbaum, James T, Lin, Phoebe
Published in Expert opinion on pharmacotherapy (01.03.2013)
Published in Expert opinion on pharmacotherapy (01.03.2013)
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Enhanced sensitivity to alkylating agent in lymphocytes from patients with multiple endocrine neoplasia type 1
Itakura, Y., Sakurai, A., Katai, M., Ikeo, Y., Hashizume, K.
Published in Biomedicine & pharmacotherapy (01.06.2000)
Published in Biomedicine & pharmacotherapy (01.06.2000)
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Application of bone marrow gene marker in predicting marrow cleaning sensitivity of sulfonic acid alkylating agent
LI DEGUAN, BAI LIN, GAO KAI, SHI GUIYING, MENG AIMIN, GUAN BOWEN, SUN YUHANG
Year of Publication 14.02.2025
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Year of Publication 14.02.2025
Patent
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CAR T cell therapy in patients who have undergone previous anti-cancer alkylating agent therapy
CAMPBELL TRIONA, FULLER JOHN, RYTLEWSKI, JEFFREY, A, MASATI-HOSSAIN, AMIR
Year of Publication 22.09.2023
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Year of Publication 22.09.2023
Patent
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Investigation of bendamustine HCL in a Phase 2 study in women with resistant ovarian cancer
Baker, Amanda F., Roe, Denise J., Laughren, Cynthia, Cohen, Janice L., Wright, Heather M., Clouser, Mary C., Cui, Haiyan, Alberts, David S., Chambers, Setsuko K.
Published in Investigational new drugs (01.02.2013)
Published in Investigational new drugs (01.02.2013)
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Monofunctional alkylating agent-induced S-phase-dependent DNA damage
Schwartz, Jeffrey L.
Published in Mutation Research/Environmental Mutagenesis and Related Subjects (01.04.1989)
Published in Mutation Research/Environmental Mutagenesis and Related Subjects (01.04.1989)
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