Anticancer Potential of Sulfonamide Moieties via In-Vitro and In-Silico Approaches: Comparative Investigations for Future Drug Development
Wani, Tanveer A, Zargar, Seema, Alkahtani, Hamad M, Altwaijry, Nojood, Al-Rasheed, Lamees S
Published in International journal of molecular sciences (27.04.2023)
Published in International journal of molecular sciences (27.04.2023)
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Journal Article
Evaluation of the Possible Pathways Involved in the Protective Effects of Quercetin, Naringenin, and Rutin at the Gene, Protein and miRNA Levels Using In-Silico Multidimensional Data Analysis
Zargar, Seema, Altwaijry, Nojood, Wani, Tanveer A, Alkahtani, Hamad M
Published in Molecules (Basel, Switzerland) (21.06.2023)
Published in Molecules (Basel, Switzerland) (21.06.2023)
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Journal Article
Synthesis and Evaluation of New Coumarin Derivatives as Antioxidant, Antimicrobial, and Anti-Inflammatory Agents
Alshibl, Hanan M, Al-Abdullah, Ebtehal S, Haiba, Mogedda E, Alkahtani, Hamad M, Awad, Ghada E A, Mahmoud, Ahlam H, Ibrahim, Bassant M M, Bari, Ahmed, Villinger, Alexander
Published in Molecules (Basel, Switzerland) (16.07.2020)
Published in Molecules (Basel, Switzerland) (16.07.2020)
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Journal Article
Targeting Transcriptional CDKs 7, 8, and 9 with Anilinopyrimidine Derivatives as Anticancer Agents: Design, Synthesis, Biological Evaluation and In Silico Studies
Eskandrani, Razan, Al-Rasheed, Lamees S, Ansari, Siddique Akber, Bakheit, Ahmed H, Almehizia, Abdulrahman A, Almutairi, Maha, Alkahtani, Hamad M
Published in Molecules (Basel, Switzerland) (23.05.2023)
Published in Molecules (Basel, Switzerland) (23.05.2023)
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Journal Article
In Vitro Evaluation and Bioinformatics Analysis of Schiff Bases Bearing Pyrazole Scaffold as Bioactive Agents: Antioxidant, Anti-Diabetic, Anti-Alzheimer, and Anti-Arthritic
Alkahtani, Hamad M, Almehizia, Abdulrahman A, Al-Omar, Mohamed A, Obaidullah, Ahmad J, Zen, Amer A, Hassan, Ashraf S, Aboulthana, Wael M
Published in Molecules (Basel, Switzerland) (01.10.2023)
Published in Molecules (Basel, Switzerland) (01.10.2023)
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Journal Article
Antitumor properties of certain spirooxindoles towards hepatocellular carcinoma endowed with antioxidant activity
Al-Rashood, Sara T., Hamed, Ahmed R., Hassan, Ghada S., Alkahtani, Hamad M., Almehizia, Abdulrahman A., Alharbi, Amal, Al-Sanea, Mohammad M., Eldehna, Wagdy M.
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2020)
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2020)
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Journal Article
New quinoxaline-based VEGFR-2 inhibitors: design, synthesis, and antiproliferative evaluation with in silico docking, ADMET, toxicity, and DFT studies
Alanazi, Mohammed M, Elkady, Hazem, Alsaif, Nawaf A, Obaidullah, Ahmad J, Alkahtani, Hamad M, Alanazi, Manal M, Alharbi, Madhawi A, Eissa, Ibrahim H, Dahab, Mohammed A
Published in RSC advances (06.09.2021)
Published in RSC advances (06.09.2021)
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Journal Article
New bis([1,2,4]triazolo)[4,3-a:3′,4′-c]quinoxaline derivatives as VEGFR-2 inhibitors and apoptosis inducers: Design, synthesis, in silico studies, and anticancer evaluation
Alanazi, Mohammed M., Mahdy, Hazem A., Alsaif, Nawaf A., Obaidullah, Ahmad J., Alkahtani, Hamad M., Al-Mehizia, Abdulrahman A., Alsubaie, Sultan M., Dahab, Mohammed A., Eissa, Ibrahim H.
Published in Bioorganic chemistry (01.07.2021)
Published in Bioorganic chemistry (01.07.2021)
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Journal Article
Synthesis and in vitro anticancer activity of certain novel 1-(2-methyl-6-arylpyridin-3-yl)-3-phenylureas as apoptosis-inducing agents
Eldehna, Wagdy M., Hassan, Ghada S., Al-Rashood, Sara T., Al-Warhi, Tarfah, Altyar, Ahmed E., Alkahtani, Hamad M., Almehizia, Abdulrahman A., Abdel-Aziz, Hatem A.
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2019)
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2019)
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Journal Article
Erlotinib-Loaded Dendrimer Nanocomposites as a Targeted Lung Cancer Chemotherapy
Fatani, Wafa K, Aleanizy, Fadilah S, Alqahtani, Fulwah Y, Alanazi, Mohammed M, Aldossari, Abdullah A, Shakeel, Faiyaz, Haq, Nazrul, Abdelhady, Hosam, Alkahtani, Hamad M, Alsarra, Ibrahim A
Published in Molecules (Basel, Switzerland) (08.05.2023)
Published in Molecules (Basel, Switzerland) (08.05.2023)
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Journal Article
A Series of Isatin-Hydrazones with Cytotoxic Activity and CDK2 Kinase Inhibitory Activity: A Potential Type II ATP Competitive Inhibitor
Al-Salem, Huda S, Arifuzzaman, Md, Alkahtani, Hamad M, Abdalla, Ashraf N, Issa, Iman S, Alqathama, Aljawharah, Albalawi, Fatemah S, Rahman, A F M Motiur
Published in Molecules (Basel, Switzerland) (25.09.2020)
Published in Molecules (Basel, Switzerland) (25.09.2020)
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Journal Article
Discovery of new 3-methylquinoxalines as potential anti-cancer agents and apoptosis inducers targeting VEGFR-2: design, synthesis, and in silico studies
Alanazi, Mohammed M., Elwan, Alaa, Alsaif, Nawaf A., Obaidullah, Ahmad J., Alkahtani, Hamad M., Al-Mehizia, Abdulrahman A., Alsubaie, Sultan M., Taghour, Mohammed S., Eissa, Ibrahim H.
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2021)
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2021)
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Journal Article
Multi-stage structure-based virtual screening approach towards identification of potential SARS-CoV-2 NSP13 helicase inhibitors
El Hassab, Mahmoud A., Eldehna, Wagdy M., Al-Rashood, Sara T., Alharbi, Amal, Eskandrani, Razan O., Alkahtani, Hamad M., Elkaeed, Eslam B., Abou-Seri, Sahar M.
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2022)
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2022)
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Journal Article
Quercetin and Kaempferol as Multi-Targeting Antidiabetic Agents against Mouse Model of Chemically Induced Type 2 Diabetes
Ali, Muhammad, Hassan, Mudassir, Ansari, Siddique Akber, Alkahtani, Hamad M, Al-Rasheed, Lamees S, Ansari, Shoeb Anwar
Published in Pharmaceuticals (Basel, Switzerland) (08.06.2024)
Published in Pharmaceuticals (Basel, Switzerland) (08.06.2024)
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Journal Article
New Indazol-Pyrimidine-Based Derivatives as Selective Anticancer Agents: Design, Synthesis, and In Silico Studies
Al-Tuwaijri, Hanaa M, Al-Abdullah, Ebtehal S, El-Rashedy, Ahmed A, Ansari, Siddique Akber, Almomen, Aliyah, Alshibl, Hanan M, Haiba, Mogedda E, Alkahtani, Hamad M
Published in Molecules (Basel, Switzerland) (23.04.2023)
Published in Molecules (Basel, Switzerland) (23.04.2023)
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Journal Article
Synthesis, Cytotoxic Evaluation, and Structure-Activity Relationship of Substituted Quinazolinones as Cyclin-Dependent Kinase 9 Inhibitors
Alkahtani, Hamad M, Zen, Amer Alhaj, Obaidullah, Ahmad J, Alanazi, Mohammed M, Almehizia, Abdulrahman A, Ansari, Siddique Akber, Aleanizy, Fadilah Sfouq, Alqahtani, Fulwah Yahya, Aldossari, Rana M, Algamdi, Raghad Abdullah, Al-Rasheed, Lamees S, Abdel-Hamided, Sami G, Abdel-Aziz, Alaa A-M, El-Azab, Adel S
Published in Molecules (Basel, Switzerland) (23.12.2022)
Published in Molecules (Basel, Switzerland) (23.12.2022)
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