Introduction of the 4-(4-bromophenyl)benzenesulfonyl group to hydrazide analogs of Ilomastat leads to potent gelatinase B (MMP-9) inhibitors with improved selectivity
LeDour, Gwennaël, Moroy, Gautier, Rouffet, Matthieu, Bourguet, Erika, Guillaume, Dominique, Decarme, Martine, ElMourabit, Haquima, Augé, Franck, Alix, Alain J.P., Laronze, Jean-Yves, Bellon, Georges, Hornebeck, William, Sapi, Janos
Published in Bioorganic & medicinal chemistry (15.09.2008)
Published in Bioorganic & medicinal chemistry (15.09.2008)
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Inhibition of human leukocyte elastase, plasmin and matrix metalloproteinases by oleic acid and oleoyl-galardin derivative(s)
Moroy, Gautier, Bourguet, Erika, Decarme, Martine, Sapi, Janos, Alix, Alain J.P., Hornebeck, William, Lorimier, Sandrine
Published in Biochemical pharmacology (01.03.2011)
Published in Biochemical pharmacology (01.03.2011)
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Neutrophil elastase as a target in lung cancer
Moroy, Gautier, Alix, Alain J P, Sapi, Janos, Hornebeck, William, Bourguet, Erika
Published in Anti-cancer agents in medicinal chemistry (01.07.2012)
Published in Anti-cancer agents in medicinal chemistry (01.07.2012)
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Kinetics and Thermodynamics of Type VIII β-Turn Formation: A CD, NMR, and Microsecond Explicit Molecular Dynamics Study of the GDNP Tetrapeptide
Fuchs, Patrick F.J., Bonvin, Alexandre M.J.J., Bochicchio, Brigida, Pepe, Antonietta, Alix, Alain J.P., Tamburro, Antonio M.
Published in Biophysical journal (15.04.2006)
Published in Biophysical journal (15.04.2006)
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Simultaneous presence of unsaturation and long alkyl chain at P'1 of ilomastat confers selectivity for gelatinase A (MMP-2) over gelatinase B (MMP-9) inhibition as shown by molecular modelling studies
MOROY, Gautier, DENHEZ, Clément, ALIX, Alain J. P, HORNEBECK, William, BOURGUET, Erika, HAQUIMA EL MOURABIT, TORIBIO, Alix, DASSONVILLE, Alexandra, DECARME, Martine, RENAULT, Jean-Hugues, MIRAND, Catherine, BELLON, Georges, SAPI, Janos
Published in Bioorganic & medicinal chemistry (15.07.2007)
Published in Bioorganic & medicinal chemistry (15.07.2007)
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DNA Binding by Fagaronine and Ethoxidine, Inhibitors of Human DNA Topoisomerases I and II, Probed by SERS and Flow Linear Dichroism Spectroscopy
Ianoul, Anatoli, Fleury, Fabrice, Duval, Olivier, Waigh, Roger, Jardillier, Jean-Claude, Alix, Alain J. P, Nabiev, Igor
Published in The journal of physical chemistry. B (18.03.1999)
Published in The journal of physical chemistry. B (18.03.1999)
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Journal Article
The secondary structure and architecture of human elastin
Debelle, Laurent, Alix, Alain J. P., Wei, Shao M., Jacob, Marie‐Paule, Huvenne, Jean‐Pierre, Berjot, Maurice, Legrand, Pierre
Published in European Journal of Biochemistry (01.12.1998)
Published in European Journal of Biochemistry (01.12.1998)
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Raman and CD Spectroscopy of Recombinant 68-kDa DNA Human Topoisomerase I and Its Complex with Suicide DNA−Substrate
Fleury, Fabrice, Ianoul, Anatoli, Kryukov, Eugene, Sukhanova, Alyona, Kudelina, Irina, Wynne-Jones, Abigai, Bronstein, Igor B, Maizieres, Michaël, Berjot, Maurice, Dodson, Guy G, Wilkinson, Anthony J, Holden, Joseph A, Feofanov, Alexei V, Alix, Alain J. P, Jardillier, Jean-Claude, Nabiev, Igor
Published in Biochemistry (Easton) (13.10.1998)
Published in Biochemistry (Easton) (13.10.1998)
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Elastin as a matrikine
Duca, Laurent, Floquet, Nicolas, Alix, Alain J.P, Haye, Bernard, Debelle, Laurent
Published in Critical reviews in oncology/hematology (01.03.2004)
Published in Critical reviews in oncology/hematology (01.03.2004)
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Conformational Dependence of Collagenase (Matrix Metalloproteinase-1) Up-regulation by Elastin Peptides in Cultured Fibroblasts
Brassart, Bertrand, Fuchs, Patrick, Huet, Eric, Alix, Alain J.P., Wallach, Jean, Tamburro, Antonio M., Delacoux, Frédéric, Haye, Bernard, Emonard, Hervé, Hornebeck, William, Debelle, Laurent
Published in The Journal of biological chemistry (16.02.2001)
Published in The Journal of biological chemistry (16.02.2001)
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Structural and Antitumor Properties of the YSNSG Cyclopeptide Derived from Tumstatin
Thevenard, Jessica, Floquet, Nicolas, Ramont, Laurent, Prost, Elise, Nuzillard, Jean-Marc, Dauchez, Manuel, Yezid, Hocine, Alix, Alain J.P., Maquart, François-Xavier, Monboisse, Jean-Claude, Brassart-Pasco, Sylvie
Published in Chemistry & biology (01.12.2006)
Published in Chemistry & biology (01.12.2006)
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A fibrillin-1-fragment containing the elastin-binding-protein GxxPG consensus sequence upregulates matrix metalloproteinase-1: biochemical and computational analysis
Booms, Patrick, Ney, Andreas, Barthel, Frank, Moroy, Gautier, Counsell, Damian, Gille, Christoph, Guo, Gao, Pregla, Reinhard, Mundlos, Stefan, Alix, Alain J.P., Robinson, Peter N.
Published in Journal of molecular and cellular cardiology (01.02.2006)
Published in Journal of molecular and cellular cardiology (01.02.2006)
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Vibrations moléculaires du nitrate de di-μ-hydroxo-bis(diammine) platine (II) [(NH3)2Pt(OH)2Pt(NH3)2](NO3)2. Partie 2: analyse en coordonnées normales
Alix, Alain J. P, Manfait, Michel, Krug, Odile, Theophanides, Théophile
Published in Canadian journal of chemistry (01.09.1982)
Published in Canadian journal of chemistry (01.09.1982)
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